JP2002500889A - Ｉｌ−１６の変異体、その製造方法およびその使用 - Google Patents

Ｉｌ−１６の変異体、その製造方法およびその使用

Info

Publication number
JP2002500889A
JP2002500889A JP2000528688A JP2000528688A JP2002500889A JP 2002500889 A JP2002500889 A JP 2002500889A JP 2000528688 A JP2000528688 A JP 2000528688A JP 2000528688 A JP2000528688 A JP 2000528688A JP 2002500889 A JP2002500889 A JP 2002500889A
Authority
JP
Japan
Prior art keywords
nucleic acid
variant
sequence
prokaryotic
host cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2000528688A
Other languages
English (en)
Japanese (ja)
Inventor
クルト ラインハルト
バイアー ミヒャエル
ヴェルナー アルブレヒト
アンブロジウス ドロテー
ラング クルト
ランツェンデルファー マルティン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bundesrepublik Deutschland
Original Assignee
Bundesrepublik Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bundesrepublik Deutschland filed Critical Bundesrepublik Deutschland
Publication of JP2002500889A publication Critical patent/JP2002500889A/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5446—IL-16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2000528688A 1998-01-24 1999-01-22 Ｉｌ−１６の変異体、その製造方法およびその使用 Ceased JP2002500889A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98101232.1 1998-01-24
EP98101232 1998-01-24
PCT/EP1999/000428 WO1999037781A1 (en) 1998-01-24 1999-01-22 Mutants of il-16, processes for their production, and their use

Publications (1)

Publication Number Publication Date
JP2002500889A true JP2002500889A (ja) 2002-01-15

Family

ID=8231307

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000528688A Ceased JP2002500889A (ja) 1998-01-24 1999-01-22 Ｉｌ−１６の変異体、その製造方法およびその使用

Country Status (8)

Country Link
EP (1) EP1049782A1 (es)
JP (1) JP2002500889A (es)
AU (1) AU2424399A (es)
BR (1) BR9907216A (es)
CA (1) CA2320624A1 (es)
EA (1) EA200000769A1 (es)
MX (1) MXPA00006059A (es)
WO (1) WO1999037781A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003507011A (ja) * 1999-08-05 2003-02-25 リサーチ コーポレイション テクノロジーズ，インコーポレイテッド Ｉｌ−１６拮抗剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994028134A1 (en) * 1993-05-21 1994-12-08 The Trustees Of Boston University Lymphocyte chemoattractant factor and uses thereof
CA2239704A1 (en) * 1995-12-22 1997-07-03 Bundesrepublik Dutschland, Vertreten Durch Den Bundesminister Fur Gesundheit Polypeptides with interleukin 16 activity, process for the preparation and use thereof
DE19617202A1 (de) * 1996-04-30 1997-11-06 Boehringer Mannheim Gmbh Prozessierte Polypeptide mit IL-16-Aktivität, Verfahren zu ihrer Herstellung und Verwendung
US6444202B1 (en) * 1996-11-25 2002-09-03 Bundesrepublic Deutschland, Vertreten Durch Den Bundesminister Fur Gesundheit Processed polypeptides with IL-16 activity, processes for their production and their use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003507011A (ja) * 1999-08-05 2003-02-25 リサーチ コーポレイション テクノロジーズ，インコーポレイテッド Ｉｌ−１６拮抗剤

Also Published As

Publication number Publication date
CA2320624A1 (en) 1999-07-29
WO1999037781A1 (en) 1999-07-29
EA200000769A1 (ru) 2001-02-26
BR9907216A (pt) 2000-10-24
EP1049782A1 (en) 2000-11-08
MXPA00006059A (es) 2003-08-01
AU2424399A (en) 1999-08-09

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Legal Events

Date Code Title Description
A045 Written measure of dismissal of application

Free format text: JAPANESE INTERMEDIATE CODE: A045

Effective date: 20040123