JP2002360230A - Displaying sheet releasing volatile agent at sustained rate - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a displaying sheet releasing a volatile agent at a sustained rate, printable with a printer, enabling individual design at small lot, and having displayed information without using a display label. SOLUTION: The displaying sheet releasing a volatile agent at a sustained rate has a printing layer printable with a printer on one surface of a substrate sheet and an adhesive layer containing impregnated volatile agent on the other surface of the sheet.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a volatile drug sustained release sheet holding a volatile drug so as to be capable of sustained release. The present invention relates to a volatile drug sustained-release display sheet having a print surface enabling printing and also being used as a display sheet such as a quality display label and a freshness maintaining sheet.

[0002]

2. Description of the Related Art Conventionally, for example, in order to maintain the freshness of bread, an adhesive formed on one surface of a film having a high barrier property (hereinafter referred to as "gas barrier property") to a volatile agent such as a polyester film. The layer is impregnated and held with an antibacterial agent such as isothiocyanate, and is stuck to the outer surface side of the individual bag of bread using this adhesive layer, and the isothiocyanate is gradually released in the individual bag. A freshness holding sheet that holds the freshness of bread inside has been proposed in Japanese Patent No. 3121887. Alternatively, a balun-shaped freshness retaining sheet obtained by laminating a gas barrier film such as a polyester film via an adhesive layer impregnated and held with an antibacterial agent such as isothiocyanate is disclosed in Utility Model Registration No. 25812.
No. 35 proposes this.

[0003]

The above-mentioned volatile drug sustained release sheet is convenient for use for purposes such as maintaining freshness, but a gas barrier film such as a polyester film is not suitable for a printer. However, in general, only a uniform design was applied to a large number of lots. Therefore, it is not suitable for individual design in small lots, and information such as the expiration date cannot be displayed on the user side, and a label for display must be prepared separately from the volatile drug sustained release sheet It had the inconvenience of. Accordingly, the present invention provides a volatile drug sustained release display that enables printing by a printer, enables individual design in small lots, and does not require a separate label for display, and enables information display on itself. The purpose is to provide a sheet. In addition, the volatile chemicals can be released slowly during use in a humid environment, and can be printed by a printer. Individual designs can be made in small lots, and no separate label is required. It is an object of the present invention to provide a volatile drug sustained release display sheet capable of displaying information on itself.

[0004]

According to the present invention, there is provided a volatile drug sustained-release display sheet according to the present invention, in which a printing layer on one side of a base sheet is printable by a printer. And an adhesive layer for impregnating and holding a volatile agent is provided on the other surface. Also,
The volatile drug sustained-release display sheet according to the second aspect is the first aspect.
The volatile drug sustained-release display sheet according to the above, wherein the base sheet is a polyethylene terephthalate (PET) film. In addition, the volatile drug sustained release display sheet according to claim 3 is the volatile drug sustained release display sheet according to claim 1, wherein the base sheet is paper or a nonwoven fabric, and the base sheet and the adhesive sheet. A gas barrier layer made of a hydrophilic polymer that forms a sustained release film in response to moisture is provided between the gas barrier layer and the agent layer. The volatile drug sustained release display sheet according to claim 4 is the volatile drug sustained release display sheet according to any one of claims 1 to 3, wherein the printing layer is a thermosensitive coloring layer. . A volatile drug sustained release display sheet according to claim 5 is the volatile drug sustained release display sheet according to any one of claims 1 to 4, wherein the volatile drug is an isothiocyanate. I do. The volatile drug sustained release display sheet according to claim 6 is the volatile drug sustained release display sheet according to any one of claims 1 to 5, wherein a release sheet is attached to the adhesive layer. I do. Further, the volatile drug sustained release display sheet according to claim 7 is the volatile drug sustained release display sheet according to any one of claims 1 to 5, wherein a cover sheet is attached to the adhesive layer. I do. The volatile drug sustained release display sheet according to claim 8 is the volatile drug sustained release display sheet according to claim 7, wherein the cover sheet is any one of a polyethylene film, a polypropylene film, and a polymethylpentene film. It is characterized by. Further, the volatile drug sustained release display sheet according to claim 9 is characterized in that the volatile drug sustained release sheet according to any one of claims 1 to 8 is configured as a quality display label and freshness holding sheet. .

[0005]

BEST MODE FOR CARRYING OUT THE INVENTION The volatile agents to be retained in the pressure-sensitive adhesive layer include isothiocyanate esters such as allyl isothiocyanate, mustard and wasabi extracts,
Natural essences such as 8-cineole, cinnamon, garlic and the like, synthetic oils thereof, ethanol, propylene glycol and the like can be used arbitrarily according to the purpose of use. Isothiocyanates such as allyl isothiocyanate, which have an effect, are preferred.

The pressure-sensitive adhesive constituting the pressure-sensitive adhesive layer for impregnating and holding the volatile agent includes various types of acrylic, urethane, silicone, rubber, and vinyl ether based on the type of the volatile agent to be impregnated and held. An adhesive can be used, and in particular, when an isothiocyanate is used as a volatile agent, it is preferable to use an acrylic adhesive. After forming the pressure-sensitive adhesive layer by the pressure-sensitive adhesive, the pressure-sensitive adhesive layer impregnated with the volatile agent can be formed by impregnating and holding the volatile agent. The holding amount at this time is optional depending on the purpose of use,
A holding amount of about 1 to 100 parts by weight with respect to parts by weight is preferable.

[0007] As the printing layer, paper, synthetic paper, non-woven fabric having printability, coated paper provided with a coating layer for improving printability, art paper, cast coated paper, or a heat-sensitive layer is provided. Paper and synthetic paper. There is no particular limitation on the method of laminating the paper or the like having the printing suitability to the base sheet, and the lamination is performed using an adhesive or an adhesive, or the synthetic resin such as a polyethylene resin is melt-extruded and laminated on the base sheet. You can also. In addition, polyester resin, acrylic resin, urethane resin,
A resin layer such as a styrene resin, a clay coat layer in which a filler or a pigment is blended with these resins, a pressure-sensitive coloring layer, or a heat-sensitive coloring layer may be provided. It is preferable to provide a thermosensitive coloring layer on the base sheet, which does not make the sheet thick and is easy to print with a printer.

Examples of the base sheet include a polyethylene terephthalate film having a high gas barrier property, a polyamide film, a polyvinylidene chloride film, a polyacrylonitrile film, a metal foil, a sheet obtained by combining them, and a polyethylene film having a low gas barrier property. A polypropylene film, a polymethylpentene film, a polyethylene naphthalate film, a polyvinyl chloride film, a paper, a nonwoven fabric, a synthetic paper, and a sheet in which pores are provided in the base sheet having a high gas barrier property. Among these, the volatile drug sustained-release display sheet of the present invention is attached to the outer surface of a product packaged with paper, polyethylene film, or polypropylene film having a low gas barrier property, for example, a food material packaging material film. And
When a volatile agent is passed through the packaging material to obtain an antibacterial and antifungal effect, the substrate sheet is preferably a substrate sheet having a high gas barrier property, and among them, a polyethylene terephthalate film is particularly preferable. It is preferable for long-lasting effects and from an economic viewpoint.

[0009] In addition, products packed with a high gas barrier property, for example, polyethylene terephthalate film,
For example, when affixing to the inner surface of a packaging material film for foods, the base material sheet is antibacterial by passing a volatile agent, and in order to obtain an antifungal effect, particularly, the base material sheet having a low gas barrier property is preferable. At the same time, the volatile agent is retained until the volatile agent sustained release display sheet is attached, and after the application, the volatile agent is dissolved by the moisture of the product (foods) and the volatile agent can be slowly released. It is preferable to provide a gas barrier layer of molecules between the base sheet and the pressure-sensitive adhesive layer that holds the volatile agent impregnated. In this case, when water droplets adhere to the substrate sheet having a low gas barrier property, paper or nonwoven fabric which absorbs the water droplets and is easily diffused is preferable.

Examples of the hydrophilic polymer include polyvinyl alcohol, carboxymethyl cellulose, ethylene / vinyl alcohol copolymer, vinyl acetate / vinyl alcohol copolymer, hydroxypropyl cellulose, cellophane and the like. The amount of the hydrophilic polymer applied or the amount of extrusion molding is not particularly limited, but is usually 3 to 50.
g / ^{m 2,} in particular, 5 to 40 g / ^{m 2} is preferred. 3g /
If it is less than m ² , sufficient gas barrier properties may not be obtained, and if it exceeds 50 g / m ² , the time until the effect is obtained may be too long.

According to the above-described structure, a volatile drug sustained release display sheet capable of uniformly releasing a volatile drug uniformly when used in an environment with high humidity can be provided. That is, the function of the gas barrier layer made of a hydrophilic polymer that becomes a sustained release film in response to moisture is, for example, used by sticking a drug sustained release display sheet inside a gas barrier container containing foodstuffs. When
Since the gas barrier property is reduced by plasticization due to the moisture in the container, the volatile agent can be released from paper or nonwoven fabric, but the release of the volatile agent can be suppressed until use. In addition, since the water in the container can be evenly distributed and held in the non-woven fabric by the capillary action, the medicine can be uniformly released from the medicine-impregnated holding layer. In addition, the presence of paper or nonwoven fabric can prevent contact with a hydrophilic polymer, which is not always preferred.
In addition, for example, as disclosed in Japanese Patent Application Laid-Open No. H11-319044, a volatile polymer layer is laminated on a volatile drug layer to release the volatile drug slowly in the presence of moisture. However, when water droplets come into contact with the water-permeable polymer film, the gas barrier property of only that portion is reduced, and it may be difficult to uniformly release the drug uniformly. However, in the present embodiment, it is possible to always release the medicine uniformly without such inconvenience.

The release sheet to be adhered to the pressure-sensitive adhesive layer is preferably a release treatment using a release agent such as a silicone resin on one surface of the film having a high gas barrier property in order to prevent the release of a drug before use from the pressure-sensitive adhesive layer. It is preferable to use a release sheet subjected to the following.

Further, a cover sheet is attached to the pressure-sensitive adhesive layer, and the pressure-sensitive adhesive layer impregnated and held with the volatile agent is sandwiched between the base sheet and the cover sheet so as to be placed in the packaged product. A volatile drug sustained-release display sheet for obtaining a bactericidal and antifungal effect may be used. In this case, it is preferable to use a sheet having a low gas barrier property for at least one of the base sheet and the cover sheet. In this case, the same cover sheet as the base sheet having low gas barrier property can be used. Among them, particularly, it is stable that any one of a polyethylene film, a polypropylene film and a polymethylpentene film is used. It is preferable to obtain a sustained release effect of the volatile drug. Further, it is optional whether or not to form a print layer on the cover sheet that enables printing by a printer.

FIG. 1 to FIG. 3 show an example of the constitution of the volatile drug sustained-release display sheet of the present invention, and a base sheet 1 made of a polyethylene terephthalate film having a gas barrier property.
On one side, a printing layer 2 made of, for example, coated paper or a thermosensitive coloring layer is formed, and on the other side, a pressure-sensitive adhesive layer 3 in which a volatile agent is impregnated and held is provided. A release sheet 4 obtained by applying a silicone release agent treatment to a polyester film is attached. Printed layer 2 of volatile chemical sustained release display sheet provided on thermosensitive coloring layer
By using a thermal printer, information such as a product name, a maker, a seller, and a best-before date is printed, the release sheet is peeled off, and, as shown in FIGS. By sticking to the outer surface of the non-gas-barrier packaging sheet 30, it can be used as a so-called externally-attached quality display label and freshness holding sheet.

FIG. 4 to FIG. 6 show other constitutional examples of the volatile drug sustained-release display sheet of the present invention. For example, one side of a base sheet 1 made of paper or non-woven fabric having low gas barrier property has the above-mentioned structure. A similar printing layer 2 is formed, and a gas barrier layer 5 made of a hydrophilic polymer, which forms a sustained release film in response to moisture on the other surface, a pressure-sensitive adhesive layer 3 impregnating and holding a volatile agent, and a release sheet 4 are sequentially formed on the other surface. It is provided. If the printing layer 2 is provided with a thermosensitive coloring layer, information such as a product name, a manufacturer, and a seller is printed by a thermal printer, the release sheet 4 is peeled off, and as shown in FIGS. By sticking it on the inner surface of the lid of a gas barrier packaging container 31 made of polyethylene terephthalate having a thickness of 125 μm and wrapping the Japanese confectionery 21, it can be used as a so-called internally applied product display label and freshness holding sheet. . Further, in the case of this internal application type, by making the pressure-sensitive adhesive layer, the base material sheet, and the print layer transparent, and making the print reverse characters, the print can be confirmed from outside the packaging material.

[0016]

Next, specific examples of the volatile drug sustained-release display sheet of the present invention will be described. (Example 1) An acrylic pressure-sensitive adhesive (trade name “PA-T1”, manufactured by Lintec Corporation) was applied to one surface of a polyethylene terephthalate film (thickness: 25 μm) using a knife coater, and then dried to obtain a solid content of 30 g / m ^2. Was formed. 2. Allyl isothiocyanate was added to the pressure-sensitive adhesive layer.
A pressure-sensitive adhesive layer impregnated and held with a volatile agent was formed by impregnating and holding 0 g / m ² . Next, on the other side of the polyethylene terephthalate film, a polyester nonwoven fabric (polyester spunlace 40 g / m ² ) having printability was coated with an acrylic pressure-sensitive adhesive (trade name “P” manufactured by Lintec Corporation).
A-T1 "solid content application amount 5 g / m ² )
A printing layer was formed. A release sheet obtained by treating a polyester film (thickness: 25 μm) with a silicone release agent was attached to the pressure-sensitive adhesive layer.

When a printing test for printing was performed using an ink jet printer (trade name “PM-800C” manufactured by Epson Corporation) for the printing layer, all printing was clearly readable and excellent printability was obtained. confirmed. In addition, an antibacterial test was performed. This test was specifically performed as follows. That is, first, Escherichia col (Escherichia col) was placed in a 200 ml Erlenmeyer flask.
iJCM1649) 1ase was cultured overnight in brain heart infusion broth (37 ° C), and diluted with sterile phosphate buffer to 1 / 100,000 to prepare a bacterial solution. Next, 0.1 ml of the bacterial solution was applied to a desoxycholate medium prepared in advance in a 55 mm diameter petri dish, and the petri dish was placed in a 1 mm thick polyethylene terephthalate container (180 mm × 120 mm × 40 mm) with the lid removed. Are arranged so that the release sheet is removed from one volatile drug sustained-release display sheet (165 mm × 110 mm) obtained in this example, and the surface of the adhesive layer is simultaneously covered with the mouths of the six petri dishes. And immediately covered. At this time, a system (control) without the sample sheet was also created. 2 at 30 ℃ (more than 90% RH)
The mixture was allowed to stand for 4 hours, and the occurrence of colonies was observed. When the antibacterial properties were tested, colonies appeared in the untreated (control) medium, but no colonies appeared in the medium to which the volatile drug sustained-release display sheet of the present invention was adhered.

(Example 2) Art paper (trade name "NK Art", manufactured by Nippon Kaishi Co., Ltd., basis weight 84.9 g / m ² ) instead of the polyester nonwoven fabric of the volatile chemical sustained release display sheet of Example 1 A volatile drug sustained release display sheet was prepared in the same manner as in Example 1 except that the printing layer was formed by the method described in Example 1. When the same printing property and antibacterial property test as in Example 1 were performed, excellent printability and excellent antibacterial property were confirmed as in Example 1.

(Example 3) Synthetic paper provided with a thermosensitive coloring layer instead of the polyester non-woven fabric of the volatile drug sustained release display sheet of Example 1 (trade name "Yupo VTO" manufactured by Oji Yuka Synthetic Paper Co., Ltd.) A volatile drug sustained release display sheet was prepared in the same manner as in Example 1 except that a print layer having a thickness of 100 μm) was formed. A printability test using a thermal printer (trade name “MR400” manufactured by Sato Co., Ltd.) and an antibacterial test similar to that of Example 1 were performed. As a result, the printability was good, and the printability was excellent as in Example 1. Antibacterial properties could be confirmed.

(Example 4) Polyester nonwoven fabric (Polyester nonwoven fabric)
Stealth spun lace 40g / m²) With hydrophilic polymer
A certain polyvinyl alcohol (Kuraray Co., Ltd. product name
220 Kuraray Povar CP-1220-T10)
Extrusion at 20 ° C, solid content 20g / m²Gas barrier layer
A nonwoven fabric / PVA composite film provided with was prepared. Separately,
Silicone peeling on polyester film (25μm thickness)
Acrylic on the release agent-treated surface of the release sheet
Adhesive (Product name "PA-T" manufactured by Lintec Corporation)
1)) is applied with a knife coater and then dried to obtain a solid content.
30g / m ²Was formed. This adhesive layer
3.0 g / m 2 of allyl sothiocyanate²Impregnated,
A pressure-sensitive adhesive layer impregnated and held with a volatile agent was formed. The compound
Impregnated with gas barrier layer (PVA layer) and volatile chemicals of composite membrane
The held pressure-sensitive adhesive layer was stuck.

When the same printability test as in Example 1 was conducted, the printability was good. An antibacterial test was conducted in the same manner as in Example 1 except that 10 ml of distilled water was placed in a polystyrene container, and a volatile drug sustained-release display sheet was attached to the inside of the lid of the polystyrene container. As a result, excellent antibacterial properties were confirmed as in Example 1. Further, the release behavior of allyl isothiocyanate was confirmed. That is, the humidity and temperature were 23 ° C. × 50% and 40 ° C. × 9.
The volatile drug sustained-release display sheet was allowed to stand for 6 hours in an atmosphere of 5%, and the residual ratio of allyl isothiocyanate was measured. The residual ratio was determined from the weight change before and after the measurement of the sample. As a result, the temperature and humidity were 23 ° C. × 50% and the residual ratio was 98.0%.
At a humidity of 40 ° C. × 95%, the residual ratio was 17.5%.

Example 5 Example 5 was repeated except that the release sheet attached to the pressure-sensitive adhesive layer of Example 1 was replaced by a polypropylene film (trade name “Trefane NO3301”, 30 μm, manufactured by Toray Synthetic Film Co., Ltd., 30 μm) as a cover sheet. In the same manner as in Example 1, a volatile drug sustained release display sheet was prepared. When the same printing property and antibacterial property test as in Example 1 were performed, excellent printability and excellent antibacterial property were confirmed as in Example 1. The antibacterial test was performed in the same manner as in Example 1, except that the surface of the polypropylene film was covered with a petri dish.

[0023]

As described above, according to the volatile drug sustained-release display sheet of the present invention, since a printing layer that enables printing by a printer is formed on the sheet base, printing by the printer is enabled. Individual design is possible in small lots, and information can be displayed on its own without the need for a separate display label. Further, when the substrate sheet is paper or non-woven fabric, and provided a gas barrier layer of a hydrophilic polymer that becomes a sustained release film in response to moisture between the substrate sheet and the pressure-sensitive adhesive layer Is capable of uniformly releasing volatile chemicals when used in an environment with high humidity, enables printing with a printer, enables individual design in small lots, and does not require separate display labels. , The information can be displayed on itself.

[Brief description of the drawings]

FIG. 1 is a structural cross-sectional view showing one structural example of a volatile drug sustained-release display sheet of the present invention.

FIG. 2 is a sectional view showing the configuration in the same use state.

FIG. 3 is a perspective view showing the same use state.

FIG. 4 is a sectional view showing another example of the configuration of the volatile drug sustained-release display sheet of the present invention.

FIG. 5 is a sectional view of the configuration showing the same use state.

FIG. 6 is a perspective view showing the same use state.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Base sheet 2 Printing layer (thermosensitive coloring layer) 3 Adhesive layer 4 Release sheet 5 Gas barrier layer 20 Isobe mochi 21 Japanese confectionery 30 Packaging sheet with low gas barrier property 31 Packaging container with high gas barrier property

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI Theme coat ゛ (Reference) C09J 7/02 C09J 7/02 Z 4F100 11/02 11/02 4J004 201/00 201/00 4J040 D06M 13 / 272 D06M 13/272 4L033 13/322 13/322 4L055 D21H 27/00 D21H 27/00 A // A61L 2/20 A61L 2/20 G B05D 7/00 B05D 7/00 F 7/04 7/04 (72 ) Inventor Koshiro Nagaoka 23-23 Honcho, Itabashi-ku, Tokyo F-term in Lintec Co., Ltd. (reference) 4B021 LA15 LA16 LA17 LW09 MC01 MK24 MP07 4C058 AA21 BB07 CC09 EE02 EE13 EE15 EE16 JJ16 JJ21 4D075 AE19 CA12 CA13 CA35 CA45 CA47 DA04 DB01 DB18 DB36 DB38 DB43 DB53 DC36 EA06 EA07 EB19 EB52 EC07 4F100 AH04C AK01D AK04E AK07E AK08E AK25C AK41B AK41E AK42A AK52E AR00E AT00A BA03 BA04 BA05 BA07 BA10B BA10C CA12C CA16C DG10A DG15A DG15B GB15 HB31B JB05D JC00 JC00C JD02D JL13C JL14E JN28B 4J004 AA17 AB01 CA06 CB01 CB02 CC02 CC03 CD02 DB03 FA01 4J040 CA001 DD051 DF001 EF001 EK001 KA29 LA11 NA06 4L033 AA07 AB07 BA23 BA25 BA44 4L055 AG36 AG46 AG64 AH50 AJ02 AJ03 BE08 BE14 FA30 GA12 GA27 GA42

Claims (9)

[Claims] 1. A volatile chemical release agent comprising a printing layer provided on one side of a base sheet and capable of being printed by a printer, and an adhesive layer holding and impregnating and holding a volatile agent on the other side. Release display sheet. 2. The volatile drug sustained-release display sheet according to claim 1, wherein the base sheet is a polyethylene terephthalate film. 3. The method according to claim 1, wherein the base sheet is paper or nonwoven fabric, and a gas barrier layer made of a hydrophilic polymer which becomes a sustained release film in response to moisture between the base sheet and the adhesive layer. 2. The volatile drug sustained-release display sheet according to claim 1, wherein the sheet is provided. 4. The volatile drug sustained release display sheet according to claim 1, wherein the printing layer is a thermosensitive coloring layer. 5. The volatile drug sustained-release display sheet according to claim 1, wherein the volatile drug is an isothiocyanate. 6. The volatile drug sustained-release display sheet according to claim 1, wherein a release sheet is attached to the pressure-sensitive adhesive layer. 7. The volatile drug sustained-release display sheet according to claim 1, wherein a cover sheet is attached to the pressure-sensitive adhesive layer. 8. The volatile drug sustained release display sheet according to claim 7, wherein the cover sheet is any one of a polyethylene film, a polypropylene film and a polymethylpentene film. 9. The volatile chemical sustained release display sheet according to claim 1, wherein the volatile chemical sustained release display sheet is configured as a quality display label / freshness maintaining sheet.