JP2002255838A - Method for improving taste and taste-improved lotus embryo extract preparation - Google Patents
Method for improving taste and taste-improved lotus embryo extract preparationInfo
- Publication number
- JP2002255838A JP2002255838A JP2001058145A JP2001058145A JP2002255838A JP 2002255838 A JP2002255838 A JP 2002255838A JP 2001058145 A JP2001058145 A JP 2001058145A JP 2001058145 A JP2001058145 A JP 2001058145A JP 2002255838 A JP2002255838 A JP 2002255838A
- Authority
- JP
- Japan
- Prior art keywords
- taste
- germ extract
- lotus
- lotus germ
- extract preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
Description
【０００1】[0001]
【発明の属する技術分野】本発明は、ハス胚芽抽出物に
デンプン加水分解物を配合することにより、ハス胚芽抽
出物特有の渋味、収斂味等の呈味を改善する方法及び呈
味が改善されたハス胚芽抽出物製剤に関するものであ
る。TECHNICAL FIELD The present invention relates to a method for improving the taste, such as astringency and astringency, unique to a lotus germ extract by adding a starch hydrolyzate to the lotus germ extract, and to improving the taste. The present invention relates to a prepared lotus germ extract preparation.
【０００２】[0002]
【従来の技術】ハスは古来より、その実は食され、ある
いは漢方薬として使用されており、その安全性は確立さ
れている。このハスの種子の胚芽を用いたものとして、
例えば、特開昭６３−６６１２６号に、水や水混和性の
有機溶媒などを用いて抽出された抽出物が血圧降下作用
を有するとして、更には、特開昭６４−９０１２９号
に、同じくハスの胚芽から水や低級アルコールなどの溶
媒を用いて抽出された抽出物が、高血圧などの循環器疾
患や気管支喘息などの呼吸器疾患、不眠症などの中枢神
経疾患などに作用するとして、それぞれ開示されてい
る。2. Description of the Related Art Lotus has been eaten or used as a Chinese medicine since ancient times, and its safety has been established. Using the lotus seed germ,
For example, JP-A-63-66126 discloses that an extract extracted using water or a water-miscible organic solvent has a blood pressure lowering effect. Extracts extracted from the germ of the germ using a solvent such as water or lower alcohol are disclosed as acting on cardiovascular diseases such as hypertension, respiratory diseases such as bronchial asthma, central nervous diseases such as insomnia, etc. Have been.
【０００３】ハス胚芽には、アミノ酸を起源とする含窒
素有機化合物等に起因する渋味、収斂味等を有するため
服用の際、不快感を生じていた。この渋味等を取り除く
ため、カゼインなどのタンパク質との反応が試みられて
いるが、この方法では水不溶物が形成され、噴霧乾燥な
どの方法が用いられず、安価に生産することが困難であ
ると共に呈味改善の程度も十分ではなかった。The lotus germ has an astringent taste, an astringent taste, and the like due to nitrogen-containing organic compounds derived from amino acids and the like, and thus has caused discomfort when taken. In order to remove such astringency, a reaction with a protein such as casein has been attempted. However, this method forms water-insoluble substances, does not use a method such as spray drying, and is difficult to produce at low cost. In addition, the degree of taste improvement was not sufficient.
【０００４】[0004]
【発明が解決しようとする課題】本発明の目的は、食品
に使用するハス胚芽抽出物の渋味等を改善することによ
り、固有の渋味等により使用量及び用途範囲が制限され
ていたハス胚芽抽出物の使用量及び用途を拡大すること
にある。SUMMARY OF THE INVENTION An object of the present invention is to improve the astringency of a lotus germ extract used in foods, so that the amount and range of use of the lotus germ extract are limited by the inherent astringency. An object of the present invention is to expand the use amount and use of an embryo extract.
【０００５】[0005]
【課題を解決するための手段】本発明により提供された
呈味改善法及び呈味改善ハス胚芽抽出物製剤は、ハス胚
芽抽出物に分子量が１０００〜２０００のデンプン加水
分解物を混合溶解した後、噴霧乾燥、真空乾燥等の方法
を行うことを特徴とする。Means for Solving the Problems The taste improving method and the taste improving lotus germ extract preparation provided by the present invention are obtained by mixing and dissolving a starch hydrolyzate having a molecular weight of 1,000 to 2,000 in the lotus germ extract. , Spray drying, vacuum drying and the like.
【０００６】また、本発明により提供された呈味改善ハ
ス胚芽抽出物製剤は、上記本発明の方法により、ハス胚
芽抽出物に対して分子量が１０００〜２０００のデンプ
ン加水分解物を１０重量％以上加えた混合物を乾燥した
ものである。[0006] Further, according to the method of the present invention, the taste-improved lotus germ extract preparation provided by the present invention comprises a starch hydrolyzate having a molecular weight of 1,000 to 2,000 based on the lotus germ extract in an amount of 10% by weight or more. The added mixture is dried.
【０００７】[0007]
【発明の実施の形態】本発明に用いるハス胚芽抽出物と
は、すいれん科ハス属のハス（Nelumbo nucifera）の種
子中にある胚（胚芽）が用いられる。胚芽は、通常緑色
で棒状をしており、採取した種子から取り出し、直ちに
乾燥させる。BEST MODE FOR CARRYING OUT THE INVENTION As a lotus germ extract used in the present invention, an embryo (germ) in the seeds of a lotus (Nelumbo nucifera) belonging to the genus Lotus of the tremorous family is used. Embryos are usually green and rod-shaped and are removed from the collected seeds and dried immediately.
【０００８】ハス胚芽抽出物は、この胚芽を、水やメタ
ノール、エタノール、イソプロパノール等の各種脂肪族
低級アルコール、１，３−ブチレングリコール、エチレ
ングリコール、グリセリンなどの親水性有機溶媒、これ
ら親水性有機溶媒の混合物及びこれらの親水性有機溶媒
と水との混液などの各種水系溶媒を用いて抽出すること
により得られるものである。[0008] The lotus germ extract is prepared by converting the germ into water, various aliphatic lower alcohols such as methanol, ethanol and isopropanol; hydrophilic organic solvents such as 1,3-butylene glycol, ethylene glycol and glycerin; It is obtained by extraction using various aqueous solvents such as a mixture of solvents and a mixture of these hydrophilic organic solvents and water.
【０００９】また、本発明で言うデンプン加水分解物と
は、例えば、ばれいしょ、小麦粉、トウモロコシ、タピ
オカ等を原料とする澱粉を酵素または無機酸によって加
水分解処理して分子量が１０００〜２０００に分解した
ものを主成分としたものである。The starch hydrolyzate referred to in the present invention is, for example, a starch obtained from a potato, flour, corn, tapioca or the like as a raw material, which is hydrolyzed with an enzyme or an inorganic acid to a molecular weight of 1,000 to 2,000. It is mainly composed of
【００１０】分子量が１０００以下のデンプン加水分解
物では、ハス胚芽抽出物の呈味改善効果はほとんど無
く、また、分子量２０００以上のデンプン加水分解物
は、多少の改善効果は見られるものの、十分な効果では
ない。また、分子量が２０００以上のデンプン加水分解
物は、水への溶解性が悪く、取扱いの面でも本発明に用
いることは難しい。A starch hydrolyzate having a molecular weight of 1,000 or less has almost no effect of improving the taste of a lotus germ extract, and a starch hydrolyzate having a molecular weight of 2,000 or more has a sufficient effect, although a slight improvement is observed. Not an effect. A starch hydrolyzate having a molecular weight of 2,000 or more has poor solubility in water and is difficult to use in the present invention in terms of handling.
【００１１】デンプン加水分解物は、呈味改善対象であ
るハス胚芽抽出物に対して１０重量％から５００重量
％、好ましくは１００重量％から３００重量％を添加し
て、十分に混合し溶解する。デンプン加水分解物の添加
量が多い場合は、予めデンプン加水分解物を水で溶解し
た液とハス胚芽抽出物を混合しても良い。The starch hydrolyzate is added in an amount of 10% by weight to 500% by weight, preferably 100% by weight to 300% by weight, based on the lotus germ extract to be taste-improved, and sufficiently mixed and dissolved. . When the starch hydrolyzate is added in a large amount, a liquid prepared by dissolving the starch hydrolyzate with water and a lotus germ extract may be mixed.
【００１２】ハス胚芽抽出物とデンプン加水分解物の溶
解液は、直接乾燥するか必要に応じて濃縮した後、乾燥
する。The solution of the lotus germ extract and the starch hydrolyzate is dried directly or, if necessary, concentrated, and then dried.
【００１３】乾燥方法としては、加熱真空乾燥、凍結乾
燥、熱風乾燥、噴霧乾燥等の何れの方法を用いることも
できるが、コスト面や後工程の粉末化を考慮すると噴霧
乾燥が好ましい。As the drying method, any method such as heating vacuum drying, freeze drying, hot air drying and spray drying can be used. However, spray drying is preferred in view of cost and powdering in a later step.
【００１４】このように得られた乾燥ハス胚芽抽出物製
剤は、元のハス胚芽抽出物特有の渋味や収斂味をほとん
ど呈せず、経口で服用するに当たり、人に対し何ら不快
感を感じることの無い呈味の改善された製剤である。The dried lotus germ extract preparation thus obtained hardly exhibits the astringent or astringent taste peculiar to the original lotus germ extract, and feels unpleasant to humans when taken orally. It is a formulation with an improved taste without any problems.
【００１５】さらに、本発明の方法を付した呈味改善ハ
ス胚芽抽出物製剤は、服用した後、消化器官において容
易にデンプン加水分解物が消化され、ハス胚芽抽出物本
来の薬理を示す。[0015] Further, after taking the taste-improved lotus germ extract preparation to which the method of the present invention is applied, the starch hydrolyzate is easily digested in the digestive tract and shows the original pharmacology of the lotus germ extract.
【００１６】本発明の呈味改善されたハス胚芽抽出物
は、顆粒、錠剤、粉末、チュアブル、カプセル等、各種
形態に使用することが出来る。また、使用用途として
は、抗菌素材、消臭素材、苦味素材に利用することが出
来る。さらに、食品や菓子類などに用いることが出来
る。例えば、パン、チューインガム、キャンディ、グ
ミ、ゼリー、錠菓などには容易に用いることが出来る。The lotus germ extract of the present invention having an improved taste can be used in various forms such as granules, tablets, powders, chewables and capsules. In addition, it can be used for antibacterial materials, deodorant materials, and bitter materials. Furthermore, it can be used for foods and confectionery. For example, it can be easily used for bread, chewing gum, candy, gummy, jelly, tablet and the like.
【００１７】[0017]
【実施例】以下、製造例及び配合例を示して本発明を説
明するが、本発明はこれらに限定されるものではない。
なお、本実施例で用いるハス胚芽抽出物は、ハス胚芽の
粗砕物を５０重量％のエタノール水溶液により抽出した
抽出物を使用した。EXAMPLES The present invention will be described below with reference to Production Examples and Formulation Examples, but the present invention is not limited thereto.
The lotus germ extract used in this example was an extract obtained by extracting a crushed lotus germ with a 50% by weight aqueous ethanol solution.
【００１８】〔製造例１〕平均分子量１５００（商品
名：パインデックスＮｏ.２、松谷化学工業社製）５０g
を水５００mＬに溶かし、分画分子量１０００の透析膜
（商品名：スペクトラ／ポアＣＥ、分子量１０００、メ
デシナルインダストリー社製）に入れ、水道水流水中で
４８時間透析し、膜内液を減圧濃縮後、真空乾燥した。
ハス胚芽抽出物５gに透析内液乾燥物５gを混合溶解し、
減圧乾燥後、真空乾燥・粉砕によりハス胚芽抽出物製剤
９.２gを得た。[Production Example 1] 50 g of average molecular weight 1500 (trade name: Paindex No. 2, manufactured by Matsutani Chemical Industry Co., Ltd.)
Was dissolved in 500 mL of water, placed in a dialysis membrane having a molecular weight cut off of 1,000 (trade name: Spectra / Pore CE, molecular weight: 1,000, manufactured by Medicinal Industries), dialyzed in running tap water for 48 hours, and concentrated in the membrane under reduced pressure. And vacuum dried.
5 g of lotus germ extract was mixed and dissolved with 5 g of dried dialysis solution,
After drying under reduced pressure, 9.2 g of a lotus germ extract preparation was obtained by vacuum drying and pulverization.
【００１９】〔製造例２〕平均分子量２０００（商品
名：パインデックスＮｏ.１、松谷化学工業社製）５０g
を水１０００mＬに溶かし、分画分子量２０００の透析
膜（商品名：スペクトラ／ポアＣＥ、分子量２０００、
メデシナルインダストリー社製）に入れ、各６０００m
Ｌの水に対し、３回透析（温度５℃、１０時間、３回）
し、透析外液を減圧濃縮後、真空乾燥した。ハス胚芽抽
出物１５gに透析外液乾燥物５gを混合溶解し、減圧乾燥
後、真空乾燥・粉砕によりハス胚芽抽出物製剤１９.６g
を得た。[Production Example 2] 50 g of average molecular weight 2000 (trade name: Paindex No. 1, manufactured by Matsutani Chemical Industry Co., Ltd.)
Was dissolved in 1000 mL of water, and a dialysis membrane having a molecular weight cutoff of 2000 (trade name: Spectra / Pore CE, molecular weight 2000,
6000m each
Dialysis against L water 3 times (temperature 5 ° C, 10 hours, 3 times)
Then, the dialysate was concentrated under reduced pressure, and then dried under vacuum. 5 g of the dried dialysis solution was mixed and dissolved in 15 g of the lotus germ extract, dried under reduced pressure, vacuum dried and pulverized to obtain 19.6 g of the lotus germ extract preparation.
I got
【００２０】〔製造例３〕ハス胚芽抽出物２００ｇにデ
ンプン加水分解物として、平均分子量：１５００（市販
名：パインデックスNo.２、松谷化学工業社製）６００
ｇを混合溶解し、１６５℃の噴霧乾燥機で噴霧乾燥さ
せ、ハス胚芽抽出物製剤６９４gを得た。Production Example 3 200 g of Lotus germ extract as starch hydrolyzate, average molecular weight: 1500 (trade name: Paindex No. 2, manufactured by Matsutani Chemical Industry Co., Ltd.) 600
g of the mixture was spray-dried with a spray dryer at 165 ° C. to obtain 694 g of a lotus germ extract preparation.
【００２１】〔製造例４〕ハス胚芽抽出物２００ｇにデ
ンプン加水分解物として、平均分子量：２０００（パイ
ンデックスNo.１、松谷化学工業社製）２０ｇを混合溶
解し、１６５℃の噴霧乾燥機で噴霧乾燥させ、ハス胚芽
抽出物製剤２０３gを得た。[Production Example 4] 200 g of lotus germ extract was mixed with 20 g of a starch hydrolyzate having an average molecular weight of 2,000 (Paindex No. 1, manufactured by Matsutani Chemical Industry Co., Ltd.) and dissolved in a spray dryer at 165 ° C. By spray drying, 203 g of a lotus germ extract preparation was obtained.
【００２２】〔比較例１〕ハス胚芽抽出物２０ｇにデン
プン加水分解物として、製造例２で処理した透析内液乾
燥物１０ｇを混合溶解し、減圧乾燥後、粉砕してハス胚
芽抽出物製剤２８．９gを得た。[Comparative Example 1] As a starch hydrolyzate, 20 g of a lotus germ extract was mixed and dissolved as a starch hydrolyzate with 10 g of a dried dialysis inner liquid, dried under reduced pressure, and crushed to prepare a lotus germ extract preparation 28. 0.9 g was obtained.
【００２３】〔比較例２〕ハス胚芽抽出物１００ｇにデ
ンプン加水分解物として、平均分子量６５０（パインデ
ックスNo.３、松谷化学工業社製）１００ｇを混合溶解
し、１６５℃で噴霧乾燥し、ハス胚芽抽出物製剤１８３
gを得た。[Comparative Example 2] 100 g of a starch hydrolyzate having an average molecular weight of 650 (Paindex No. 3, manufactured by Matsutani Chemical Industry Co., Ltd.) was mixed and dissolved in 100 g of a lotus germ extract, and spray dried at 165 ° C. Germ extract preparation 183
g was obtained.
【００２４】〔試験例１〕 呈味改善確認試験 製造例１から４及び比較例１、２で得られたハス胚芽抽
出物製剤(以下、供試粉末という。)を用いて、ハス胚芽
抽出物のマスキングについて試験を行った。パネラーは
１８歳から５５歳までの男女各５人ずつで、各パネラー
に供試粉末０.５gを直接口に含んで唾液で口中に分散し
て呈味を確認し、「渋味、収斂味が強い（味が強い）」
「渋味、収斂味が感じられる（味を感じる）」「渋味、
収斂味なし（味がない）」の３段階評価で行った。[Test Example 1] Taste improvement confirmation test Using the lotus germ extract preparations (hereinafter referred to as test powders) obtained in Production Examples 1 to 4 and Comparative Examples 1 and 2, a lotus germ extract was used. Was tested for masking. The panelists consisted of 5 males and 5 females aged 18 to 55, each containing 0.5 g of the test powder directly in their mouth, dispersing them in the mouth with saliva, and checking the taste. Is strong (the taste is strong) "
"Astringent, astringent taste is felt (feel the taste)""Astringent,
No astringent taste (no taste) ".
【００２５】 ＜表１＞ 呈味改善試験結果ハス胚芽抽出物製剤 味が強い 味を感じる 味がない 製造例１ ０名 ０名 １０名 製造例２ ０名 ０名 １０名 製造例３ ０名 ０名 １０名 製造例４ ０名 １名 ９名 比較例１ ３名 ６名 １名 比較例２ ７名 ３名 ０名[0025] <Table 1> Preparation there is no taste to taste-improving test results lotus germ extract preparation taste feel a strong taste 1 0 people 0 people 10 people Production Example 2 0 people 0 people 10 people Production Example 3 0 people 0 Name 10 Manufacture example 4 0 1 1 9 Comparative example 1 3 6 1 Comparative example 2 7 3 0
【００２６】上記の結果から明らかなように、ハス胚芽
抽出物に対し、分子量１０００〜２０００のデンプン加
水分解物を１０重量％以上混合溶解した液を乾燥したハ
ス胚芽抽出物製剤は、呈味が改善されていた。As is clear from the above results, the lotus germ extract preparation obtained by drying a liquid obtained by mixing and dissolving a starch hydrolyzate having a molecular weight of 1,000 to 2,000 by 10% by weight or more with the lotus germ extract has a taste. Had been improved.
【００２７】〔配合例１〕 常法に従い、錠剤状健康食
品を製造した。 粉糖 １００g デキストリン ８０g モノグリセリン脂肪酸エステル ２０g 製造例３のハス胚芽抽出物製剤 １００g[Formulation Example 1] A tablet-shaped health food was produced according to a conventional method. Powdered sugar 100 g dextrin 80 g monoglycerin fatty acid ester 20 g lotus germ extract preparation of Production Example 3 100 g
【００２８】〔配合例２〕 常法に従い、ハス胚芽抽出
物製剤入りキャンディーを製造した。 グラニュー糖 ６５g 酵素糖化水飴 ３５g サイクロデキストリン ０．５g 香料 ０．１g 製造例３のハス胚芽抽出物製剤 １g 水 ２０g[Formulation Example 2] A candy containing a lotus germ extract preparation was produced according to a conventional method. Granulated sugar 65 g Enzymatic saccharified starch syrup 35 g Cyclodextrin 0.5 g Flavor 0.1 g Production lotion 3 lotus germ extract preparation 1 g Water 20 g
【００２９】〔配合例３〕 常法に従い、ハス胚芽抽出
物製剤入りチューインガムを製造した。 チューインガムベース ２０g グラニュー糖 ５０g 水飴 １５g 軟化剤 ５g 香料 ０．１g 製造例２のハス胚芽抽出物製剤 １g[Formulation Example 3] A chewing gum containing a lotus germ extract preparation was produced according to a conventional method. Chewing gum base 20g Granulated sugar 50g Syrup syrup 15g Softener 5g Flavor 0.1g Production lotion 1 lotus germ extract preparation 1g
【００３０】[0030]
【発明の効果】本発明により、ハス胚芽抽出物特有の渋
み、収斂味が改善されたハス胚芽抽出物製剤が提供さ
れ、それにより従来より広い範囲の食品に利用すること
が可能となった。Industrial Applicability According to the present invention, a lotus germ extract preparation having improved astringency and astringency unique to a lotus germ extract is provided, thereby making it possible to use it in a wider range of foods than before.
───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.7 識別記号 ＦＩ テーマコート゛(参考） Ａ６１Ｐ 25/20 Ａ６１Ｐ 25/20 // Ａ２３Ｇ 3/00 １０１ Ａ２３Ｇ 3/00 １０１ 3/30 3/30 Ｆターム(参考） 4B014 GB06 GB13 GG17 GL11 GP23 GP27 4B018 LB01 LE01 MD36 MD61 ME04 ME14 MF01 MF06 4C076 AA29 BB01 CC11 CC15 CC40 EE38 FF52 GG01 4C088 AB39 AC20 BA08 CA05 CA06 CA08 MA04 MA43 MA52 NA09 ZA05 ZA42 ZA59 ──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. 7 Identification symbol FI Theme coat ゛ (Reference) A61P 25/20 A61P 25/20 // A23G 3/00 101 A23G 3/00 101 3/30 3/30 F Term (Reference) 4B014 GB06 GB13 GG17 GL11 GP23 GP27 4B018 LB01 LE01 MD36 MD61 ME04 ME14 MF01 MF06 4C076 AA29 BB01 CC11 CC15 CC40 EE38 FF52 GG01 4C088 AB39 AC20 BA08 CA05 CA06 CA08 MA04 MA43 MA52 NA09 ZA05 Z42
Claims (2)
水分解物とハス胚芽抽出物を混合溶解した後、乾燥する
ことを特徴とするハス胚芽抽出物の呈味を改善する方
法。1. A method for improving the taste of a lotus germ extract, comprising mixing and dissolving a starch hydrolyzate having a molecular weight of 1,000 to 2,000 and a lotus germ extract, followed by drying.
０〜２０００のデンプン加水分解物１０重量％以上を混
合溶解した後、乾燥してなる呈味改善ハス胚芽抽出物製
剤。2. A lotus germ extract having a molecular weight of 100
A taste-improved lotus germ extract preparation prepared by mixing and dissolving 10% by weight or more of 0 to 2000 starch hydrolyzate and then drying.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001058145A JP4786041B2 (en) | 2001-03-02 | 2001-03-02 | Method for reducing astringency and astringency and lotus germ extract preparation for reducing astringency and astringency |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001058145A JP4786041B2 (en) | 2001-03-02 | 2001-03-02 | Method for reducing astringency and astringency and lotus germ extract preparation for reducing astringency and astringency |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002255838A true JP2002255838A (en) | 2002-09-11 |
| JP4786041B2 JP4786041B2 (en) | 2011-10-05 |
Family
ID=18917914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001058145A Expired - Fee Related JP4786041B2 (en) | 2001-03-02 | 2001-03-02 | Method for reducing astringency and astringency and lotus germ extract preparation for reducing astringency and astringency |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4786041B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018100247A (en) * | 2016-12-21 | 2018-06-28 | 松浦薬業株式会社 | Dextrin formulation |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6366123A (en) * | 1986-08-21 | 1988-03-24 | ベスタ−・インコ−ポレイテツド | Improved therapy for general mycotic infection by polyene antimycotic antibiotic enclosed in lipid particle |
| JPS6490123A (en) * | 1987-09-30 | 1989-04-06 | Nippon Kayaku Kk | Nitroglycerol spray agent |
| JPH02207768A (en) * | 1989-02-08 | 1990-08-17 | Maruzen Kasei Co Ltd | Removal of bitter taste from glycyrrhizin-containing solution |
-
2001
- 2001-03-02 JP JP2001058145A patent/JP4786041B2/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6366123A (en) * | 1986-08-21 | 1988-03-24 | ベスタ−・インコ−ポレイテツド | Improved therapy for general mycotic infection by polyene antimycotic antibiotic enclosed in lipid particle |
| JPS6490123A (en) * | 1987-09-30 | 1989-04-06 | Nippon Kayaku Kk | Nitroglycerol spray agent |
| JPH02207768A (en) * | 1989-02-08 | 1990-08-17 | Maruzen Kasei Co Ltd | Removal of bitter taste from glycyrrhizin-containing solution |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018100247A (en) * | 2016-12-21 | 2018-06-28 | 松浦薬業株式会社 | Dextrin formulation |
Also Published As
| Publication number | Publication date |
|---|---|
| JP4786041B2 (en) | 2011-10-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5866179A (en) | Medicated chewing gum and a process for preparation thereof | |
| CN100484551C (en) | Xylitol green tea preparation for clearing mouth smell and preventing decayed tooth and its preparation process | |
| EP1970366A1 (en) | Isohumulone compound clathrate and composition containing the same | |
| JP2005526854A (en) | Chewable composition containing psyllium gel-forming extract | |
| CN112074195A (en) | Apple vinegar nutritional supplement | |
| JP7018019B2 (en) | Beverage powder plant extract and its manufacturing method | |
| JP4057163B2 (en) | Beauty food | |
| US11533929B2 (en) | Green tea film composition | |
| JPH04316459A (en) | Solid material containing propolis, its production and its use | |
| WO2005094859A1 (en) | Agent improving moisture-retention function of skin | |
| JPH08191664A (en) | Production of new coffee extract | |
| KR101841950B1 (en) | Method for reducing unpleasant taste | |
| JP2742868B2 (en) | Beverages containing propolis extract | |
| JP2010166876A (en) | Fermented black turmeric and method for producing the same | |
| JP2001199886A (en) | Taste-improving method and proanthocyanidin preparation for improving taste | |
| JP2002255838A (en) | Method for improving taste and taste-improved lotus embryo extract preparation | |
| KR102604237B1 (en) | Composition for enhancing the bioavailability of fat-soluble vitamins | |
| JP2960703B2 (en) | Method for producing Maitake extract powder and preparation containing Maitake extract powder | |
| JP5083504B2 (en) | Oral hair restorer and oral composition for hair growth | |
| JP2001103918A (en) | Method for improving gustatoriness and gustatoriness- improved persimmon juice preparation | |
| JP4456785B2 (en) | Moon peach leaf and stem extract composition, moon peach leaf and stem extract-containing food and drink, and method for improving taste of moon peach leaf and stem extract | |
| JP3034652B2 (en) | Composition for removing or suppressing bad breath | |
| JPH04148654A (en) | Honey-containing powder and its production | |
| JP4503951B2 (en) | Diabetes disease prevention and treatment agent | |
| TWI825159B (en) | Composition for oral ingestion that contains ingredients derived from turmeric and is chewed and/or dissolved in the oral cavity |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20071127 |
|
| RD03 | Notification of appointment of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7423 Effective date: 20071127 |
|
| RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20071214 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20110315 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20110516 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20110628 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20110713 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 Ref document number: 4786041 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20140722 Year of fee payment: 3 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |