JP2002193786A - Bath agent - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a bath agent enhancing the moisturizing action of bath agent and the cleaning effect to the skin, excellent in ameliorating effect to a rough or damaged skin and imparting a sufficient moist feeling, smooth feeling and flexibility to the skin after taking bath by using plants belonging to genus Bidens or their extract. SOLUTION: This bath agent having enhanced ameliorating effect especially action to a cutaneous symptom in other words prickly heat, eczema, pimple, rough skin or the like by formulating plants belonging to genus Bidens, especially Bidens pilosa L or its extract.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a bath preparation which has an excellent effect of improving skin symptoms such as rash, eczema, acne, inflammation, cracks and irritations.

[0002]

2. Description of the Related Art A bathing agent is a mixture of an inorganic salt, a crude drug, an enzyme, an organic acid, a humectant, and the like, and a fragrance, a coloring agent, and the like. These bath additives enhance the warm bath effect and skin cleansing effect of bathing,
It moisturizes the skin and relaxes the body and mind. Many organic acids, crude drug extracts, oils and fats, essential oil components, and the like have been used as moisturizing agents, but their moisturizing and smoothing feeling after bathing are not sufficient.
Therefore, the present invention has an excellent bathing effect, especially an excellent moisturizing effect and a cleansing effect, and an excellent effect of improving rough or damaged skin.
It is an object of the present invention to provide an excellent bathing agent which gives a sufficiently moist feeling, a smooth feeling and a suppleness to the skin after bathing.

[0003]

[Means for Solving the Problems] The genus Sendangsa, especially Bidens pirosa, is a weed of the Asteraceae family native to tropical and subtropical regions. In addition to being taken as a folk medicine for diseases, it is also used for diabetes and rheumatism, and is also used externally to wash wounds and gargle with extracts. The present inventor focused on the usefulness of the present plant, and as a result of various studies, recognized various excellent effects in animal experiments. From the user of the present invention, it was found that when drinking as a tea and then putting in hot water at the time of bathing, the feeling of use was extremely excellent and two birds per stone. Therefore, as a result of intensive research conducted by blending this with a bath salt, among those generally considered to be the effects of bath salts, it is particularly useful for skin, that is, it is extremely effective in improving skin symptoms such as rash, eczema, acne, roughness. The inventor found that the usability was good, and completed the present invention.

The Asteraceae family of the genus Asteraceae used in the present invention is described in detail in Japanese Patent Application No. 2000-105559.
A group of plants called Bidens in the scientific name, and they cross each other in a wide variety of species. Although it is extremely difficult to do this, the Sendangusa plants used in the present invention include those listed below.

[0005] Bidens pilosa L. (Bidens pilosa, Koshironosendangusa, Xianfeng grass) Bidens pilosa L.var. Minor (Blume ) Sherff ( Shirobanasendangusa, Jono Bidens, Koshironosendangusa, Bidens pilosa, Xianfeng grass) Bidens pilosa L.var. Bisetosa Ohtani et S. Suzuki
(Millet Yuki Bidens) Bidens pilosa Lf decumbens Scherff (high millet snow Bidens) Bidens pilosa L.var. Radiata Scherff (Tachi millet Yuki Bidens, which may include a high-bubbles snow Bidens) Bidens pilosa L.var. Radiata Schultz Bipontinus ( Jono Bidens, Oba nano Bidens) Bidens biternata Lour.Merrill et Sherff (Bidens) Bidens bipinnata L. (edge Roh Bidens, Bidens) Bidens cernua L. (willow Bidens Tripartita) Bidens frndosa L. (Bidens frondosa, Say Takata Acanthopanax) Bidens parviflora Willd ( e buckwheat Roh Bidens) Bidens radiata Thuill.var. pinnatifida (Turcz .) Kitam
ura (Ezonotaucogi) Bidens tripartita L. (Taukogi)

[0006] This plant is mainly called Xianfeng in China and Taiwan, but it is also known by a lot of synonyms. There are names such as shrimp grass, sign cause grass, mark cause head, red stake, Kanasa silver board, wind sown, south wind sward, shrimp shears, scrutinized certain pupils, etc., and which scientific name each corresponds to Not clear.

[0007] The flowers are peculiar to the Asteraceae family, with several tongue-like flowers, such as white or yellow round petals, and a large number of yellow-brown tubular flowers in the center. Some lack tongue-shaped flowers. The stem has square, light purple colored nodes. The leaves, which are divided into three or five wings, have a handle, and the edges are jagged, and many of them are opposed to each other.

In Japan, it is found south of the warm region of Honshu, Taiwan,
It is distributed throughout China and the tropics of the world, and its plant height is 25 cm to about 1 m. It is usually an annual plant, but when it is blessed with mild climatic conditions, it overwinters and flowers bloom all year round. There are needles with barbs at the top of the black-brown seeds carried on the clothes of animals and humans, and the number of needles is often uneven due to mating. In China, it is called Onikosa.

[0009] The plant of the genus Sendangsa is usually used by drying the above-ground part, but whole plants including roots may be used. The drying method may be sun drying, shade drying, or ventilation drying with a dryer, but drying at 80 ° C. or less is desirable. The harvest may be made at any time, but since seeds with needles are attached after the flowers, it is desirable to have as few seeds as possible, that is, before the flowers bloom or until the flowers.

In order to use the plant of the genus Sendanga used in the present invention as a bathing agent, the plant is used as a medicinal plant bathing agent.
Alternatively, the dried and chopped product may be packed together with other medicinal plants in Japanese paper, cloth, nonwoven fabric, or the like. An extract or a soluble dry extract powder may be blended with a bathing agent mainly containing ordinary salts.

To prepare the extract, an organic solvent such as methanol or ethanol, or propylene glycol or butylene glycol may be used. However, if a dry powder is obtained immediately, the extract may be extracted with warm water. The extraction temperature is desirably 80 ° C. or less as much as possible. The extract may be used as it is, or if necessary, decolorized or purified by a standard method,
It may be used after being concentrated. The powder may be used as a powder by a suitable method such as spray drying or drum drying.

When the plant of the genus Sendangsa is used as a bath product as a dry product, it is preferable to use 1 g to 100 g, preferably 2 g to 30 g per serving of about 200 L of hot water in a home tub. When used as an extract or extract powder, a considerable amount may be used in terms of the original dried plant.
That is, a bathing agent is usually used at home for 10 g to 3 g per dose.
Since 0 g is used, in the case of a medicinal plant bath agent, it is used alone or in combination with other medicinal plants. In the case of a bath agent mainly composed of salts, for example, the extract powder is obtained in a yield of 10% from the original dried plant. If the extract powder is 0.1g per serving
10 to 10 g, preferably 0.2 to 3 g.

The bathing agent of the present invention may contain any components which are usually added to the bathing agent, in addition to the plant of the genus Genus or the extract thereof. The dosage form is powder type, granule type, tablet type, liquid type,
Alternatively, a bag type may be used.

Hereinafter, the present invention will be described with reference to Test Examples and Examples, but the present invention is not limited thereto.

[0015]

[Test Example 1] Moisturizing action 92 g of water was added to 8 g of the dried matter of Pirosa and extracted at 80 ° C for 72 hours with occasional stirring. 1 g of the filtrate was spread thinly on a petri dish and kept at 0% humidity for up to 24 hours. The remaining weight was measured. As a control, 1 g of pure water was similarly placed in a petri dish, and the weight was measured similarly. As shown in Table 1, it was confirmed that the filtrate of Bidens-Pirosa extract was less likely to evaporate than pure water regardless of humidity conditions, that is, it had a moisturizing property.

Table 1 Elapsed time 0 3 6 924 Extract 100 63.0 36.5 23.8 18.6 Pure water 100 43.5 8.16 3.96 0.20

[0017]

Test Example 2 Anti-Inflammatory Activity Five-week-old male mice were preliminarily reared for one week, and then each group was divided into three mice. Each extract of Example 4 was applied at 1 mg / 20 μL to the inside and outside of the right pinna of the mice. Acetone 20 in control group
μL and 0.5 mg / 20 indomethacin for the positive control group.
μL was applied. After 30 minutes, TPA (12-O-Tetr
adecanoylphorbol-13-acetat
e) 0.5 mg / 20 μL was applied to the same site of all mice to cause artificial inflammation, and the thickness of the pinna was measured 5 hours later. As a result, the inflammation inhibitory effect of indomethacin, a medical anti-inflammatory agent, was 79.4%, that of the product of the present invention was 53.3%, and that of methanol extract was 79.1%, as compared with the control group. In particular, methanol extract showed an anti-inflammatory effect comparable to indomethacin. % Inhibition control group 0.0 indomethacin group 79.4 ^* ethyl acetate extract group 53.3 ^** methanol extract group ^{79.1 ** *: p <0.005 (} Student's t-test) **: p <0 .0005 (Student's t-test)

[0018]

Example 1 Extraction of 1,3-butylene glycol of Bidens-Pirosa 1,000 g of 1,3-butyleneglycol was added to 50 g of dried whole plant of Bidens-Pirosa (cosendangsa) and extracted at room temperature for 10 days. After filtration and concentration under reduced pressure, 100 g of a 1,3-butylene glycol extract of Bidens pirosa was obtained. 1 g of this product is equivalent to about 0.5 g of dried Bidens-Pirosa.

[0019]

Example 2 Ethanol Extract of Bidens Pirosa Ethanol 2,000 g was added to 100 g of dried whole plant of Bidens Pirosa (Shirobanasendangusa), extracted at room temperature for 7 days, filtered, and the filtrate was concentrated to dryness. By solidification, 8.0 g of an ethanol extract of Bidens pirosa was obtained.
1 g of this product is equivalent to about 12.5 g of dried Bidens-Pirosa.

[0020]

Example 3 Hot water extract of Bidens-Pirosa A 2 L water was added to 100 g of dried whole plant of Bidens-Pirosa, and extracted for 5 hours at 90-100 ° C with occasional stirring, followed by filtration. The filtrate was concentrated to dryness to obtain 23.1 g of Bidens-Pirosa hot water extract. 1 g of this product is equivalent to about 4.3 g of dry matter of Bidens-Pirosa.

[0021]

EXAMPLE 4 Ethyl acetate and methanol extract of Bidens pirosa 108 kg of the above-ground part of Bidens pirosa was washed with water and steamed. I got something. 4kg
The mixture was added with 9 L of ethyl acetate, extracted with heating under reflux for 3 hours and filtered. The solvent was evaporated to 89 g.
Was obtained. The residue was similarly extracted with methanol to obtain 185 g of an extract. About 1 part of this ethyl acetate extract
g and about 2 g of the methanol extract, it is equivalent to about 45 g of dried Bidens-Pirosa.

[0022]

Example 5 Liquid Bath Agent (for Home Use 5 Times) Bidens-Pirosa Extract Obtained in Example 1 30.0 Chimney Extract 2.0 Ethanol 35.0 Methyl Benzoate 0.1 Solubilizer 1.9 Perfume Dye Trace water Total appropriate amount 100.0 The above components were taken in a weight ratio, and the total amount was set to 100 with water to obtain a liquid bath agent. As a control, a preparation was prepared using the same amount of 1,3-butylene glycol instead of the Bidens-Pirosa extract.

[0023]

[Example 6] Powdered bath agent (for household use 5 times) Bidence pilosa extract obtained in Example 2 4.0 Sodium sulfate 75.0 Sodium bicarbonate 15.0 Dispersant 0.5 Fragrance / pigment Trace dextrin Appropriate total amount 100.0 Take the above components in a weight ratio, and add the total amount to 1 with dextrin.
It was set to 00 as a powdered bath agent. As a control, a preparation was prepared using the same amount of dextrin instead of the Bidens-Pirosa extract.

[0024]

Example 7 Medicinal plant bath agent (for household use) 10 g of dry matter of Bidence Pirosa (Tachiawayukisendangusa), 2 g of dry matter of Shoub, 10 sodium sulfate
g, 3 g of sodium carbonate and 5 g of sodium chloride were packed in a nonwoven bag to prepare a medicinal plant bath agent. As a control, a mixture of the same amount of dried chamomile instead of the dried Bidens-Pirosa was prepared.

[0025]

Example 8 Powdered Bubble Bath Bath Agent (for 3 Household Uses) Bidence Pirosa Extract Obtained in Example 3 10.0 Sodium Sulfate 40.0 Sodium Lauryl Sulfate 34.0 Silicic Anhydride 10.0 Titanium Oxide 5 0.0 EDTA 1.0 Perfume / dye Trace total 100.0 The above components were taken in a weight ratio to prepare a powder bubble bath bath agent. As a control, a preparation was prepared using the same amount of sodium chloride instead of the Bidens-Pirosa extract.

[0026]

[Example 9] Granule type bath salt (for home use 5 times) Ethyl acetate extract obtained in Example 4 2.0 Same methanol extract 4.0 Sodium sulfate 70.0 Sodium carbonate 70.0 Sodium carboxymethyl cellulose 2. 0 Perfume / Dye Trace total 150.0 The above components were taken in a weight ratio, and if necessary, a small amount of water was added, kneaded and mixed uniformly, extruded and granulated, and then dried by ventilation to prepare a granular type bath preparation. As a control, a preparation was prepared using the same amount of sodium chloride instead of the Bidens-Pirosa extract.

[0027]

[Evaluation method] The bath preparations of Examples 5 to 9 were distributed to volunteers who had a family living together and were taking a bath using the bath preparation in a normal household, and investigated the feeling of use including 2 to 5 families. .
In other words, one volunteer was asked to compare and evaluate one kind of bath salt with a control, and one kind of bath salt was evaluated by at least 10 people, so that a total of five kinds (including each control) 10 prototypes). To the evaluator, simply give No. 1 and No. 2 so that the prototype and the control product cannot be distinguished. For the same liquid bath agent, Evaluator A controls No. 1 and Evaluator B controls No. 2 Although it was not a strict double-blind test, we took care to avoid prejudice as much as possible. In the evaluation, evaluation was made by focusing on four items: feeling of hot water during bathing, feeling of moistness of the skin after bathing, smoothness of the skin after bathing, and heat retaining effect after bathing.

The evaluator was a high school student or higher. The bathing temperature was 40 ° C., the time for immersion in the bathtub was 4 to 5 minutes, and the evaluation score was given about 30 minutes after bathing. Table 2 summarizes the evaluation results.

[0029]

[Evaluation results] Table 2 Total of control products for both Bidens-PirosaIt is better to enter   Example 5 7 8 7 7 3 2 3 2 1 1 1 2 11 Example 6 4 7 7 7 6 6 3 2 2 2 2 3 3 12 Example 7 7 9 9 6 4 1 1 3 0 0 0 1 10 Example 8 5 9 9 7 5 1 1 3 1 1 1 1 1 11Example 9 5 6 8 6 6 5 3 3 4 2 2 2 3 13 Feeling of hot water during bathing Moist feeling of skin after bathing Smoothness of skin after bathing Warming effect after bathing

That is, it was overwhelmingly evaluated that all of the bath preparations having different dosage forms of Examples 5 to 9 had better contain Bidens Pirosa. Then, from November to December, when I asked the applicant to use the prototype with Bidence Pirosa for 1 to 1.5 months,
As a feeling of use, it seems that those with Bidens Pirosa healed children's abrasions faster, healed small cuts held by a cut bun, healed fingertips rough, heels There were many reports that the feeling of cramps on the soles and feet was considerably reduced.

From the above, it has been confirmed that a bath containing the component of Bidens pirosa exhibits an excellent effect of improving the condition of the skin among various requirements expected of the bath.

Claims (2)

[Claims] 1. A bath preparation comprising a plant of the genus Sendangsa or an extract thereof. 2. The bath preparation according to claim 1, wherein the plant of the genus Sendangsa is Bidens pirosa.