JP2002047199A - Method for enhancing efficacy of crude drug - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a new crude drug therapeutic agent utilizing vital energy in crude drug therapy. SOLUTION: This method for enhancing the efficacy of the crude drug is characterized by subjecting a crude drug extract liquid to treatment with electromagnetic waves at 50-250 MHz and 100-300 W for 30 s to 10 min, energization at 30-100 kHz and 3-10 V for 30-60 s, magnetic treatment at 10-3,000 Gausses and treatment with ultrasonic waves at 100-300 W for 3-10 min alone or in combination simultaneously.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a method for enhancing the efficacy of a crude drug.

[0002]

2. Description of the Related Art Oriental medicine using crude drugs has a long history and achievements, but further improvement is required for treatment of intractable diseases such as cancer, AIDS and collagen disease.

[0003]

In view of the state of the art as described above, the present invention seeks to provide a method for enhancing the efficacy of crude drugs used in Oriental medicine.

[0004]

As a result of various studies to solve the above-mentioned problems, the present inventor has applied "ki" in oriental medicine, specifically, "careful" or The above problem was solved by "generating the energy". More specifically, the present inventor has first found that the above problem can be solved by applying a predetermined electromagnetic wave to a crude drug, and has completed the present invention. Therefore, the present invention applies three electromagnetic waves of 50 to 250 MHz to the crude drug extract.
Provided is a method for enhancing the effect of a crude drug, which is performed for 0 second to 30 minutes.

[0005]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The method of the present invention can be applied to various crude drugs, and is not particularly limited. For example, the method can be applied to crude drugs such as indigenous parasites, Kousan and Tenjusan. Diseases that can be treated with the crude drug treated by the method of the present invention are not particularly limited, but are effective for treating various cancers, such as intractable diseases, AIDS, collagen disease, rheumatoid arthritis, and the like. Examples of the types of cancer include lung cancer, breast cancer, liver cancer, and skin cancer.

In the present invention, a crude drug extract as described above is treated. The extract is obtained by treating a crude drug with water or hot water according to a conventional method, and a specific method has been established in the art for each crude drug and application. The extract is irradiated with electromagnetic waves of 50 to 250 MHz for 30 seconds to
Obtained by applying for 30 minutes. The intensity of the electromagnetic wave is preferably from 100 to 300 W. As the generator of the electromagnetic wave, a common generator or the like can be used.

[0007] In a preferred embodiment of the present invention, the effectiveness is enhanced by applying electricity, ultrasonic waves or magnetism to the treatment with electromagnetic waves. As the magnetism, magnetism that does not change periodically is applied. The magnetic strength is preferably from 1,000 to 3,000 Gauss. Energization is 30kHz ~ 100kHz, 3 ~ 10V, 30 ~
More preferably, the ultrasonic wave is added at 100 to 300 W for 3 to 10 minutes for 60 seconds. When these two types are applied to the electromagnetic wave, the order may be any order. The treatment by electromagnetic waves, ultrasonic waves or magnetism, for example, while passing the herbal extract through, for example, a synthetic resin tube that passes magnetism,
It can be performed by applying electromagnetic waves or magnetism from outside. Further, instead of the electromagnetic wave, a light stimulus which is considered to have substantially the same physical effect may be applied.

[0008]

Next, the present invention will be described more specifically with reference to examples. Embodiment 1 FIG. A daily amount of crude drug (Changakusan), 28 g, was extracted with 500 mL of water at 100 ° C. to obtain a drug extract. Extract liquid
In the case where no electromagnetic wave treatment was performed, administration was carried out as it was, and in the case of electromagnetic wave treatment, a 117 MHz electromagnetic wave having an intensity of 200 W was applied for about 1 minute. The patient's immunity is measured by using immune lymphocytes (NK
Or the number and balance of T cells
In Oriental medicine, it was measured by the intensity of "sanity" by pulse diagnosis.

A crude drug extract which had not been subjected to electromagnetic wave treatment was administered to a 53-year-old male lung cancer patient at a dose of 28 g for 2 months, but there was no marked increase in immunity. Subsequently, when the crude drug extract subjected to the electromagnetic wave treatment was administered for 3 months, the immunity increased with time. The result is shown in FIG. Immunity started to increase from the point where the administration of the crude drug extract without electromagnetic wave treatment was changed to the administration of the crude drug extract treated with electromagnetic wave, confirming the effect of the electromagnetic wave treatment on the crude drug extract.

Embodiment 2 FIG . Crude drug (Tenjusan (No. 7)) 2
Eight grams were extracted with 300 mL of water at 100 ° C., and administered without treatment with electromagnetic waves, and applied with 117 W electromagnetic waves of 200 W intensity for about 1 minute when treated with electromagnetic waves. The patient's immunity was measured as in Example 1.

When a 52-year-old male lung cancer patient was treated with the above-mentioned dose of the herb extract treated with electromagnetic waves for 2 months, the immunity increased with time. Thereafter, when the administration was switched to administration of a crude drug extract that had not been subjected to electromagnetic wave treatment, the immunity decreased over time. The result is shown in FIG. From these results, it is clear that electromagnetic wave treatment of the crude drug extract is effective for improving immunity in cancer-bearing patients.

Case 1. (71-year-old woman) Right mastectomy (T _2n1 M ₀ = St, October 1979)
age II). Postoperatively, radiation therapy, MMC and 5FU
Provided chemotherapy until 1983. Thereafter, no recurrence was found, and the patient was followed up because his general condition was good.

In March 1988, he returned due to general malaise and dyspnea. Numerous metastatic recurrences were found in the lungs and liver. The chemotherapy treatment was started immediately, but the side effects were remarkable and the efficacy against the tumor was not recognized. Therefore, the chemotherapy was discontinued, and the treatment was changed to a Chinese medicine treatment mainly comprising Changhakusan and Astol BW. The tumor marker value at this point was CEA (71.
7), CA15-3 (6110). In addition, CE
A is a special protein produced by cancer cells with a blood measurement value of 2.5 or more in cancer-bearing patients. CA15-3 is a tumor marker specific to breast cancer and has a normal value of 35 or less.

Chohaku-san is a herbal medicine complex for increasing immunity and fully exerting its function.
Bukuryo, seaweed and licorice are the main agents. Astol is a plant extract that can improve immunity and measure cell properties. In each case, the enforcement conditions were electromagnetic waves (200 W, 117
MHz), magnetic (1800 gauss), ultrasonic (130 W,
5 minutes), and electromagnetic waves and magnetism were applied through a polyurethane tube.

[0015] In April 1988, the above symptoms improved,
L (Quality of Life; quality of life) improved significantly, and she was discharged soon. January 1989, CT
Above, the metastatic image completely disappeared and there was no subjective symptom. 199
In May 2000, there was no recurrence and no CT abnormalities.
September 1990, tumor marker values CEA (3.5), C
A15-3 (32.5).

FIG. 3 shows the course of treatment. FIG. 4 shows an X-ray CT image of the liver at the time of readmission. A large number of circularly dark portions are cancer metastasis images. Fig. 4 shows the crude drug (Changakusan +
(Astol) CT image of liver 3 months after the start of treatment. The metastases appear to have gradually melted. FIG. 7 is a liver CT image 6 months after the crude drug treatment. The tumor image of cancer metastasis is gradually disappearing. Fig. 7 shows C one year after starting crude drug treatment.
It is a T image. Metastatic cancer has almost completely disappeared. FIG.
Is a CT image of the lung before the herbal medicine treatment, and many small circular cancer shadows are observed. FIG. 8 is a CT image of the lung 6 months after the start of the crude drug treatment, and the small circular shadow has almost disappeared.

Case 2. (68-year-old woman) After undergoing a left mastectomy in April 1989, she received various treatments.
On the moon, a number of metastatic lesions were found on the cervical vertebra, thoracic vertebra, lumbar vertebra, left and right ribs, pelvis, etc. on a bone scintigraph (FIG. 9). 1
From February to March 996, anorexia was remarkable and almost inedible, and the tumor marker CA15-3 rose to nearly 4,000.

In May 1996, Changhakusan and Astol
Oriental medical treatment was started with BW (treated in the same manner as in case 1), the pain gradually decreased, the appetite gradually recovered, and the tumor markers gradually improved. 1996
In July, he gained weight, his appetite almost recovered, and his tumor markers continued to decline. In September 1996, metastatic lesions almost disappeared in bone scintigraphy (FIG. 10). 199
In October 2006, the tumor marker AC15-3 recovered to 40.2, and almost daily life became possible.

[0019]

As described above, the pharmacological effect of a crude drug is remarkably improved by subjecting the crude drug to electromagnetic wave treatment, ultrasonic wave, electric current and magnetic treatment according to the present invention.

[Brief description of the drawings]

FIG. 1 is a graph showing that administration of a crude drug treated with electromagnetic waves of the present invention significantly increases immunity compared to administration of a crude drug not treated with electromagnetic waves.

FIG. 2 is a graph showing that the increased immunity due to the administration of a crude drug treated with electromagnetic waves of the present invention decreases with the administration of an untreated crude drug.

FIG. 3 is an example of a graph showing the progress of treatment in the case of treating liver and lung metastases of breast cancer with a crude drug treated according to the present invention.

FIG. 4 is a photograph showing a CT image of the liver at the start of the treatment according to the present invention, and is a drawing substitute photograph showing the form of an organism.

FIG. 5 is a photograph showing a CT image of the liver three months after the start of the herbal medicine treatment of the present invention, and is a drawing substitute photograph showing the form of an organism.

FIG. 6 is a photograph showing a CT image of a liver 6 months after the start of the herbal medicine treatment of the present invention, and is a drawing substitute photograph showing the form of an organism.

FIG. 7 is a photograph showing a CT image of the liver one year after the start of the herbal medicine treatment of the present invention, and is a drawing substitute photograph showing the form of an organism.

FIG. 8 is a photograph showing a CT image of the lung at the start of the treatment according to the present invention, and is a drawing substitute photograph showing the form of an organism.

FIG. 9 is a photograph showing a CT image of the lung 12 months after the start of treatment with the crude drug of the present invention, and is a drawing substitute photograph showing the form of an organism.

FIG. 10 is a bone scintigraph of Case 2, taken in January 1996 (at the start of treatment with the crude drug of the present invention), and is a photograph substituted for a drawing, showing the morphology of an organism.

FIG. 11 is a bone scintigraph in September 1996 in Case 2, which is a drawing-substituting photograph showing the form of an organism.

Claims (3)

[Claims] 1. A method for enhancing the efficacy of a crude drug, comprising applying an electromagnetic wave of 50 to 250 MHz to the crude drug extract for 30 seconds to 30 minutes. 2. The method according to claim 1, further comprising applying a magnetic field of 1000 to 3000 Gauss. 3. The method according to claim 1, wherein the potentiating effect is enhancing the immunopotentiating / modulating action of the crude drug.