JP2002034956A - Component measuring device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a component measuring device capable of measuring a prescribed component in blood accurately and securely in a short period of time. SOLUTION: The component measuring device 1 mainly comprises a main body 2, a finger rest part 3, a puncture means 4 stored in a housing 5, a chip retracting mechanism 6, a pump 8, an electromagnetic valve, and a measuring means 7 for detecting collection of blood and measuring a prescribed component in the collected blood. The chip 13 is mounted on the housing 5, and the top of the chip 13 is sealed with a finger pressing against the finger rest part 3. By pressing an operation button 222, a puncture needle of the chip 13 punctures the finger tip, and the pump 8 reduces the pressure inside the housing 5 and the punctured part. Then blood is sucked from the punctured part and when the collection of blood is detected, the pump 8 is stopped, the electromagnetic valve opened, the reduced pressure condition released. After that, the prescribed component of blood is measured by the measuring means 7, processed by a control means 11, and the result of the measurement is displayed on a display part 12.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a component measuring apparatus, and more particularly, to a blood test, in which a fingertip is punctured with a puncture needle to collect blood and to determine the amount of a specific component such as glucose in the blood. The present invention relates to a component measuring device for measuring.

[0002]

2. Description of the Related Art In recent years, with the increase in the number of diabetic patients, self-monitoring of blood glucose, which monitors daily fluctuations in blood glucose level, has been recommended.

In order to measure the blood glucose level, a test paper that develops a color according to the amount of glucose in the blood is mounted, blood is supplied to the test paper, the blood is developed, and the color is developed. The measurement (colorimetry) is performed using a blood glucose measuring device that quantifies the blood glucose level.

Prior to this measurement, as a method for the patient to collect his or her own blood, the patient's skin is punctured using a puncture device equipped with a puncture needle or a scalpel, and the area around the puncture is pressed with a finger or the like. The blood is squeezed out.

[0005] However, the fingertips are concentrated in capillaries and are suitable for collecting blood. On the other hand, the nerves are concentrated and painful. Because it involves fear,
Many patients are unable to continue their own blood glucose measurements.

In a conventional blood glucose measurement, a puncture operation and
Since the blood collection operation and the measurement operation are performed separately, the operability is also poor.

[0007]

SUMMARY OF THE INVENTION An object of the present invention is to provide a component measuring apparatus capable of accurately and reliably measuring a predetermined component in blood in a short time.

[0008]

This and other objects are achieved by the present invention which is defined below as (1) to (10).

(1) A component measuring device which is used by mounting a chip provided with a puncture needle and a test paper, wherein a finger contact portion for applying a finger to be punctured, and a finger applied to the finger contact portion are provided. Puncturing means for operating the puncture needle to puncture,
Decompression means for reducing the pressure of the puncture site of the finger with the puncture needle together with the storage space for the puncture needle and the test paper, and the amount of the predetermined component in the blood collected from the puncture site and spread on the test paper Measuring means for measuring the blood sampling, blood sampling detecting means for detecting the blood sampling, and at least reduced pressure releasing means for releasing or relaxing the reduced pressure state of the storage space for the test paper, the blood sampling detecting means When the collection of blood is detected, at least the reduced pressure state of the storage space for the test paper is released or relaxed by the decompression releasing means, and then the amount of the predetermined component in the collected blood is measured by the measuring means. A component measuring device characterized by being configured as described above.

(2) The component measuring apparatus according to (1), wherein the measurement requires a predetermined component in the atmosphere.

(3) The component measuring device according to the above (1) or (2), wherein the decompression releasing means has a flow path for communicating the storage space with the outside, and a valve for opening and closing the flow path.

(4) The decompression releasing means has a flow path communicating the storage space with the outside, and the flow path has at least a portion having a relatively large air passage resistance. The component measuring device according to (1) or (2).

(5) The component measuring device according to any one of (1) to (4), wherein at least a part of the measuring means and at least a part of the blood sampling detecting means are also used mutually. .

(6) The component measuring device has a housing that holds the chip and houses the puncturing means.
The component measuring device according to any one of the above (1) to (5), wherein the pressure reducing unit sets the storage space in the housing in a reduced pressure state.

(7) The component measuring device according to the above (6), wherein the decompression releasing means releases or reduces the decompressed state of the storage space in the housing.

(8) The component measuring apparatus according to any one of (1) to (7), wherein the operation of the puncturing means and the operation of the pressure reducing means can be started almost simultaneously.

(9) The chip according to the above (1) to (8), wherein the chip has a contact portion for contacting a finger, and is used so as to close an opening formed inside the contact portion with the finger. The component measuring device according to any one of the above.

(10) The component measuring apparatus according to any one of (1) to (9), wherein the test paper is a test paper for measuring blood glucose.

[0019]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The present inventor has developed a blood glucose measuring device which integrates a puncturing device and a measuring device and has a suction means for squeezing blood in order to solve the conventional problems. Patent applications have been filed (Japanese Patent Application Nos. 10-183794 and 10-330057).

In these blood glucose measuring devices, first, a fingertip is pressed against the tip of the chip, and the opening of the tip is sealed so as to maintain airtightness.

Next, after the fingertip is punctured with a puncture needle protruding from the distal end opening, the suction means is operated (in a reduced pressure state) in this state, blood is sucked from the punctured site, and the blood is collected. Then, the blood glucose level of the collected blood is measured by the measuring device. The following shows an example of a chemical reaction formula between glucose (D-Glucose) in blood and a reagent when measuring a blood glucose level.

[0022]

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As can be seen from the above chemical reaction formula, a sufficient amount of oxygen is required for measuring the blood sugar level, and if the amount of oxygen is insufficient, an accurate blood sugar level cannot be obtained.

However, the blood glucose measuring device may measure the blood glucose level in a reduced pressure state, and in this case, there is a possibility that the blood glucose level is insufficient and an accurate blood glucose level cannot be obtained.

In order to solve such a drawback, the present inventor releases or alleviates the depressurized state prior to the measurement, thereby sufficiently supplying oxygen (atmospheric components necessary for the measurement). The inventors have found that the present invention can be performed, and have completed the present invention.

Hereinafter, a component measuring apparatus of the present invention will be described in detail based on a preferred embodiment shown in the accompanying drawings.

FIG. 1 is a perspective view schematically showing a first embodiment of a component measuring apparatus according to the present invention. FIG. 2 is a longitudinal sectional view showing an example of the configuration of a chip used in the present invention.
Are respectively a longitudinal sectional view showing a configuration example of a puncturing means and a housing incorporating a puncturing means included in the component measuring device of the first embodiment, and FIGS. 5 to 10 are respectively components of the component measuring device of the first embodiment. FIG. 11 is a longitudinal sectional view showing a configuration example of a main part, FIG. 11 is a block diagram showing a circuit configuration of the component measuring device of the first embodiment, and FIG. 12 is a control operation of a control unit of the component measuring device of the first embodiment ( (Partially includes an operation of an operator, etc.). 1 to 10
The middle and right sides are described as “base end” and the left side as “top end”.

As shown in FIGS. 1, 5 and 11, a component measuring device (blood component measuring device) 1 according to the first embodiment comprises:
The main body 2, a finger pad 3 installed on the main body 2, a puncturing means 4 housed in a housing 5, a tip retracting mechanism 6 provided on a base end side of the housing 5, and detection of blood collection Measuring means 7 for measuring a predetermined component in blood collected together with the pump; and a pump 8 for reducing the pressure inside the housing 5
And a solenoid valve 26 for releasing, relaxing or holding the reduced pressure state in the housing 5, a battery (power supply) 9, a control unit 11 provided on a circuit board 10, and a display unit 12.

The component measuring apparatus 1 is used with a chip 13 attached thereto, and is used for measuring a predetermined component in the air (for example, oxygen, carbon dioxide, water vapor, etc.) in a chemical reaction when measuring a predetermined component in blood. I need. Hereinafter, each component will be described.

The main body 2 is composed of a housing 21 and a lid 22 facing each other. The main body 2 has a storage space 23 formed therein. In the storage space 23, the puncturing means 4, the housing 5, the tip retreat mechanism 6, the measuring means 7, the pump 8, the solenoid valve 26, and the battery 9, circuit board 10,
The control means 11 and the display unit 12 are respectively housed.

An opening 21 penetrating through the inside and outside of the housing 21 and having a circular cross section is formed in a wall portion 211 on the distal end side of the housing 21.
2 are formed. The chip 13 is mounted (held) on the housing 5 described later via the opening 212.

On the surface on the tip end side of the wall portion 211, a finger pad 3 corresponding to the shape of the fingertip (finger) is provided so as to surround the outer periphery of the opening 212. This finger rest 3
A finger contact surface 31 is formed on the distal end side of. The component measuring device 1 is operated while the fingertip is in contact with the finger contact portion 3 (finger contact surface 31). Thereby, the fingertip is punctured, and the amount of a predetermined component (hereinafter, glucose is described as a representative in the present embodiment) in the collected blood is measured.

On the upper surface of the lid 22, a display window (opening) 221 is formed which penetrates the inside and outside of the lid 22, and the display window 221 is closed by a plate-like member made of a transparent material. Have been.

The storage space 23 corresponding to the display window 221
The display unit 12 is installed at a position inside the inside. Therefore, various information displayed on the display unit 12 can be confirmed through the display window 221.

The display section 12 is, for example, a liquid crystal display element (L
CD) and the like. The display unit 12 can display, for example, power on / off, power supply voltage (remaining battery level), measured value, measurement date and time, error display, operation guidance, and the like.

An operation button 2 is provided on the upper surface of the lid 22.
22 are installed. In the component measuring device 1, by pressing the operation button 222, the puncturing means
Subsequently, the pump (pressure reducing means) 8 is configured to operate sequentially or almost simultaneously.

The power of the component measuring device 1 may be turned on by pressing the operation button 222.

On the lower side of the display section 12 in FIG.
The control means 11 constituted by a microcomputer is mounted on the circuit board 10.
The control unit 11 controls various operations of the component measuring device 1, such as determining whether or not blood has been collected. Also,
The control means 11 has a built-in arithmetic unit for calculating the amount of glucose in blood (blood sugar level) based on a signal from the measuring means 7.

On the lower left side of the circuit board 10 in FIG. 1, a pump 8 is provided as a decompression means (suction means). The pump 8 is operated by electric power, and is connected via a tube 81 to an air passage 54 formed in the housing 5 described later. This tube 81 has flexibility, for example, polyvinyl chloride, polyethylene,
Polypropylene, ethylene-vinyl acetate copolymer (EV
A) such as polyolefins, polyamides, polyesters,
It is made of a polymer material such as silicone rubber and polyurethane.

The pump 8 is provided in the cavity 5 of the housing 5.
By sucking and discharging the air in the housing 2, the housing 5
Of the inner cavity 52 is set in a reduced pressure state.

The pump 8 is capable of sucking blood from the puncture site of the fingertip (for example, 100 to 40).
(About 0 mmHg) as long as the inner cavity 52 of the housing 5 and the puncture site of the fingertip can be brought into a reduced pressure state.

On the lower right side of the circuit board 10 in FIG. 1, a battery 9 is installed as a power source. The battery 9 is electrically connected to the pump 8, the electromagnetic valve 26, the control unit 11, the display unit 12, and the like, and supplies power necessary for the operation thereof.

On the front side of the pump 8 in FIG.
Is installed. This measuring means 7 includes a chip 1 described later.
3 optically detects the supply (collection) of blood to the test paper 18 provided in the test paper 3 and optically measures the amount of glucose in the blood spread on the test paper 18. In a state where the chip 13 is mounted and held in the housing 5, the tip 13 is located near the side where the test paper 18 is located.

As described above, the measuring means 7 has both the function of detecting the collection of blood and the function of measuring the amount of glucose (predetermined component) in the blood spread on the test paper 18. The number of parts can be reduced, the configuration can be simplified, and the number of assembling steps of the apparatus can be reduced as compared with the case where the means are separately provided.

The measuring means 7 has a light emitting element (light emitting diode) 71 and a light receiving element (photodiode) 72.

The light emitting element 71 is electrically connected to the control means 11, and the light receiving element 72 is electrically connected to the control means 11 via the amplifier 24 and the A / D converter 25.

The light emitting element 71 operates according to a signal from the control means 11 and emits light. This light is preferably pulsed light that emits intermittently at predetermined time intervals.

When the light emitting element 71 is turned on with the chip 13 mounted on the housing 5, the light emitted from the light emitting element 71 is applied to the test paper 18, and the reflected light is received by the light receiving element 72. It is photoelectrically converted. Light receiving element 72
Outputs an analog signal corresponding to the amount of received light, and after the signal is amplified as desired by the amplifier 24,
The signal is converted into a digital signal by the / D converter 25 and input to the control means 11.

The control means 11 determines whether or not blood has been collected, that is, whether or not blood has been spread on the test paper 18 of the chip 13 based on the input signal.

Further, the control means 11 performs predetermined arithmetic processing on the basis of the input signal and, if necessary, performs correction calculation to obtain the amount of glucose in blood (blood glucose level). The obtained blood sugar level is displayed on the display unit 12.

1, a housing 5 containing the puncturing means 4 and a tip retracting mechanism 6 connected to the base end of the housing 5 are provided on the near side of the measuring means 7 in FIG.

The chip retracting mechanism 6 is fixed to the casing 21, while the housing 5 is not fixed to the casing 21, but is moved in the axial direction (left and right directions in FIG. 1) by the chip retracting mechanism 6. It is installed so that it can be moved.

As described above, this component measuring device 1
The chip 13 is mounted on the housing 5 for use. As shown in FIG. 2, the tip 13 includes a puncture needle 14, a first housing 15 for slidably storing the puncture needle 14,
A second housing 16 installed on an outer peripheral portion of the first housing 15, a test paper fixing portion 17 installed on an outer peripheral portion of the second housing 16, and a test paper 18 fixed on the test paper fixing portion 17. It is composed of

The puncture needle 14 includes a needle 141 and a needle 141.
And a hub 142 fixed to the base end side of the first housing 15, and housed in the lumen 152 of the first housing 15.

The needle body 141 is formed of a hollow member or a solid member made of a metal material such as stainless steel, aluminum, an aluminum alloy, titanium, and a titanium alloy, and has a sharp cutting edge (needle tip) at its tip. Is formed. With this cutting edge, the surface (skin) of the fingertip is punctured.

The hub 142 is formed of a substantially columnar member, and its outer peripheral portion slides while being in contact with the inner peripheral surface 151 of the first housing 15.

A reduced diameter portion 143 is formed at the base end of the hub 142. The reduced diameter portion 143 is used for the needle holder 4 of the plunger 41 constituting the puncturing means 4 described later.
11 is fitted.

The first housing 15 is formed of a bottomed cylindrical member having a wall 153 as a bottom, and has a lumen 152 formed therein.

At a substantially central portion of the wall 153, a hole 154 having a circular cross section is formed. This hole 154
The needle 141 passes through when the fingertip (finger) is punctured. The diameter of the hole 154 is set smaller than the outer diameter of the tip of the hub 142. For this reason, when the puncture needle 14 moves toward the distal end of the lumen 152 and the distal end of the hub 142 abuts against the proximal end of the wall 153, the puncture needle 14 is prevented from further moving in the distal direction. Is done. Therefore, the length of protrusion of the needle body 141 from the tip of the tip 13 is kept constant when the fingertip is punctured. Therefore, it is possible to more reliably prevent the blade tip of the needle body 141 from piercing the fingertip deeper than necessary.

Further, a mechanism for adjusting the moving distance of the plunger 41 described later may be provided so that the puncturing depth of the fingertip by the cutting edge of the needle body 141 may be adjusted.

The outer periphery of the first housing 15 is
Is fixedly mounted.

The second housing 16 is formed of a substantially cylindrical member, and has a lumen 161 formed therein.

At the tip of the second housing 16,
A contact portion 163 projecting in a ring shape is formed. The contact portion 163 is a portion against which a fingertip is pressed, and inside the contact portion 163, a distal end opening (opening) 16 through which the lumen portion 161 opens.
2 are formed. The outer peripheral edge of the distal end of the contact portion 163 has a shape suitable for exerting an effect of stimulating a peripheral portion of the puncture when pressed against a fingertip and reducing pain at the time of puncture. Further, when the pressure is reduced by the pump 8, the shape is such that the inflow of air from between the tip of the contact portion 163 and the surface of the fingertip can be suppressed as much as possible. In addition,
The contact portion 163 may not be provided at the tip of the second housing 16, and the tip surface of the second housing 16 may constitute a flat surface.

The second housing 16 has a contact portion 163
A ring-shaped flange 164 that protrudes outward is formed on the outer peripheral portion near the base end. This flange 1
Reference numeral 64 designates a position with respect to the housing 5 in a state in which the base end thereof abuts on the distal end of the housing 5 when mounted on the housing 5 described later.

A concave portion 165 is formed on the outer peripheral portion of the second housing 16, and a test paper fixing portion 17 on which a disk-shaped test paper 18 is set is mounted in the concave portion 165.

The blood introduction guide 1 protruding toward the inner cavity 161 is provided on the inner peripheral surface of the second housing 16.
66 are formed. This blood introduction guide 166
It has a function of receiving blood (sample) flowing into the lumen 161 from the distal end opening 162 after the fingertip puncture.

In such a chip 13, a blood passage 19 communicating between the inner cavity 161 of the second housing 16 and the outside is formed through the second housing 16 and the test paper fixing portion 17. The blood passage 19 is a flow passage for guiding blood obtained by puncturing to the test paper 18, and has a passage opening 191 opened to the lumen 161 and a passage opening 192 opened to the outside of the chip 13. ing. The passage opening 192 is located at the center of the test paper 18.

The blood introduction guide 166 is formed near the passage opening 191. For this reason, the blood received by the blood introduction guide 166 efficiently passes through the passage opening 1.
It is led from 91 to the blood passage 19. This blood reaches the passage opening 192 by capillary action, and the passage opening 192
Is supplied to the central portion of the test paper 18 installed so as to close the surface, and develops radially.

The test paper 18 has a reagent supported on a carrier capable of absorbing and developing blood.

Examples of the carrier include a sheet-like porous material such as a nonwoven fabric, a woven fabric, and a stretched sheet.
This porous body preferably has hydrophilicity.

The reagent carried on the carrier is appropriately determined depending on the component to be measured in the blood (sample). For example, in the case of blood glucose measurement, glucose oxidase (GOD)
And peroxidase (POD), for example, 4-aminoantipyrine, N-ethyl N- (2-hydroxy-3-
A color-forming agent (color-forming reagent) such as sulfopropyl) -m-toluidine; and those which react with blood components such as ascorbate oxidase, alcohol oxidase, and cholesterol oxidase depending on the components to be measured. And the same coloring agent (coloring reagent). Further, a buffer such as a phosphate buffer may be further contained. Needless to say, the types and components of the reagents are not limited to these.

Such a chip 13 is provided in the housing 2 described above.
It is detachably attached (fitted) to the housing 5 (fitting portion 53) through one opening 212.

As shown in FIGS. 3 and 4, the housing 5 is formed of a cylindrical member having a bottom with a wall 51 as a bottom, and a lumen (storage space) 52 is formed inside the housing. ing. A fitting portion 53 whose inner diameter is reduced corresponding to the shape of the outer periphery of the chip 13 is formed on the tip end side of the housing 5. The chip 13 is inserted into the fitting portion 53 and fitted (fixed). In FIGS. 3 and 4,
To facilitate understanding of the description, the structure of the chip 13 is simplified.

On the side of the housing 5, there is formed a ventilation passage 54 for communicating the inner cavity 52 with the outside.
Is connected to the pump 8 via a tube 81.
The air in the lumen 52 is supplied to the air passage 54 and the tube 81.
The inside of the cavity 52 (including the inside of the chip 13) is depressurized.

As shown in FIG. 5, one end of a tube 82 is connected to the middle of the tube 81, and the other end of the tube 82 is open to the outside of the main body 21. The tube 82 has flexibility and can be made of, for example, the same material as the tube 81.

In the middle of the tube 82, an electromagnetic valve 26 for opening and closing (opening / closing) the flow path is provided.

When the solenoid valve 26 is closed (in the closed state), the reduced pressure state of the inner cavity 52 (including the inside of the chip 13) is maintained, and when the solenoid valve 26 is opened (when it is opened). , A tube 82 in the lumen portion 52 in the decompressed state.
Air (atmosphere) from outside through the air passage 81 and the ventilation path 54
Is introduced, and the reduced pressure state is released or alleviated.

Therefore, the tube (flow path) 81,
The pressure-reducing means is constituted by 82 and the electromagnetic valve 26.

As shown in FIGS. 3 and 4, a hole 511 is formed in the wall portion 51 of the housing 5 at a substantially central portion thereof. A thin tube 65 having an orifice (passage) 651 formed therein is provided in the hole 511. Through the orifice 651, air flows between the lumen 52 provided on both sides of the thin tube 65 and a variable volume chamber 631 described later.

A ring-shaped seal ring (sealing member) 55 is fitted to the tip of the housing 5. Thus, when the chip 13 is mounted on the housing 5, the chip 1
The base end of the third flange 164 and the seal ring 55 are in contact with each other, and the airtightness of the lumen 52 is maintained.

The seal ring 55 is made of an elastic material. Examples of such an elastic body include natural rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, nitrile rubber, chloroprene rubber, butyl rubber, acryl rubber, ethylene-propylene rubber, hydrin rubber, urethane rubber, silicone rubber, and fluorine rubber And various thermoplastic elastomers such as styrene, polyolefin, polyvinyl chloride, polyurethane, polyester, polyamide, polybutadiene, and fluororubber.

The housing 5 has a ring-shaped flange 56 projecting outward on the outer periphery of the base end thereof, and a cylindrical projection 59 formed at the base end thereof.

The puncturing means 4 is housed in the cavity 52 on the proximal side of the fitting portion 53 of the housing 5. The puncture means 4 moves the puncture needle 14 attached thereto in the distal direction, and punctures the surface of the fingertip with the cutting edge of the needle body 141.

The puncturing means 4 includes a plunger 41 and a coil spring (biasing member) for biasing the plunger 41 in the distal direction.
42 and a coil spring (biasing member) 43 for biasing the plunger 41 in the proximal direction.

At the tip of the plunger 41, a cup-shaped needle holder 411 is provided. This needle holder 411
, The reduced diameter portion 143 of the puncture needle 14 is detachably fitted. At the base end of the plunger 41, there is provided an elastically deformable elastic piece 412 having a protruding locking portion 413 at the distal end.

In a state before the tip 13 is mounted on the housing 5, that is, before the puncture needle 14 is mounted on the plunger 41 (see FIG. 3), the locking portion 413 is moved by the elastic force of the elastic piece 412. 3, and is urged upward in the middle to abut the inner peripheral surface of the housing 5. On the other hand, when the tip 13 is mounted on the housing 5, that is, when the puncture needle 14 is mounted on the plunger 41 (see FIG. 4), the locking portion 413 is formed so as to penetrate through the inside and outside of the housing 5. Inserted into 57 and locked to its edge. Thereby, the movement of the plunger 41 in the tip direction is restricted. The opening 57 is closed by a flat sealing member (sealing member) 58, and the airtightness of the lumen 52 is maintained. The seal member 58 can be made of the same material as the seal ring 55.

The coil spring (spring for puncturing) 42 is installed on the base end side of the plunger 41, and both ends thereof are
It is in contact with plunger 41 and wall 51. on the other hand,
The coil spring (push-back spring) 43 includes a plunger 41.
And both ends thereof are in contact with the plunger 41 and the fitting portion 53, respectively.

As shown in FIG. 3 and FIG. 4, an unlocking portion is provided on the outside of the housing 5 so that the locking portion 413 can be moved into the inner cavity 52 (in the direction of the arrow in the drawing). A member 223 is provided. This unlocking member 2
23 moves in conjunction with the pressing of the operation button 222 described above.

When the locking portion 413 is locked in the opening 57, the coil spring 42 is in a compressed state and urges the plunger 41 toward the distal end. Press the operation button 222 to move the unlocking member 223 in the direction of the arrow in the figure,
When the locking state of the locking portion 413 is released, the coil spring 42 is released.
Extends, moves the plunger 41 in the distal direction, and the cutting edge of the needle 141 pierces the surface (skin) of the fingertip.

On the other hand, at this time, the coil spring 43 is compressed and urges the plunger 41 in the proximal direction, that is, tries to push the plunger 41 back in the proximal direction. afterwards,
The plunger 41 performs a damping movement and stops at a position where the elastic force of the coil spring 42 and the elastic force of the coil spring 43 are balanced.

When the plunger 41 is stationary, the cutting edge of the needle 141 is stored in the tip 13.

A tip retracting mechanism 6 is provided on the base end side of the housing 5. The chip retracting mechanism 6 moves the housing 5 and the chip 13 attached thereto in a direction away from the fingertip 200 (base end direction).

The tip retracting mechanism 6 has a main body 61, a seal ring 64, and a thin tube 65, as shown in FIGS.

The main body 61 is formed of a bottomed cylindrical member having a wall 62 as a bottom, and has a lumen 63 formed therein. The proximal end side of the housing 5 is inserted into the lumen 63.

At the tip of the main body 61, a ring-shaped convex portion 611 protruding toward the center thereof is formed. In the state before the tip retreat mechanism 6 is operated, the protrusion 611
And the distal end of the flange 56 are in contact with each other. Thereby, the movement of the housing 5 in the distal direction is restricted. That is, it is possible to prevent the housing 5 from falling out of the main body 61.

At this time, the tip of the contact portion 163 is
It is almost the same position as the finger contact surface 31 or the finger contact surface 3
1 slightly (see FIG. 5). Thus, when the fingertip 200 comes into contact with the finger contact portion 3, the surface of the fingertip 200 surely comes into contact with the contact portion 163, and the tip opening 162 can be closed.

The wall portion 62 has a recess 621 having a circular cross section at a substantially central portion thereof. The diameter of the concave portion 621 is set substantially equal to the outer diameter of the convex portion 59, and the convex portion 59 is inserted into the concave portion 621. The outer diameter of the flange 56 is set substantially equal to the inner diameter of the main body 61. With such a configuration, regardless of the axial position of the housing 5, for example, a vertical displacement in the figure (a displacement between the center of the housing 5 and the main body 61) can be more reliably prevented. .

The outer periphery of the projection 59, that is, the housing 5
A ring-shaped seal ring 64 is provided between the base end of the base member and a surface 622 on the front end side of the wall portion 62. The seal ring 64 is in airtight contact with each of the base end of the housing 5 and the surface 622. As a result, in a region surrounded by the seal ring 64, the base end of the housing 5, the surface 622, and the inner surface of the recess 621, an airtight variable volume chamber (decompression chamber) 631 is defined.

The seal ring 64 is made of an elastic material, and operates the tip retracting mechanism 6 (the state shown in FIG. 8).
Then, the housing 5 is urged in the distal direction by the elastic force. That is, the seal ring 64 also functions as an urging means. As such an elastic body, a material similar to that of the seal ring 55 or the like can be used.

The thin tube 65 is formed of a cylindrical member, and has an orifice (passage) 651 formed therein. The orifice 651 is provided in the cavity 5 of the housing 5.
2 and the variable volume chamber 631 are communicated with each other. Such orifice 6
The diameter of 51 is not particularly limited.
It is preferably about 0.3 mm. Orifice 651
By setting the diameter within the above range, a necessary and sufficient air passage (flow) resistance can be obtained.

By adjusting the diameter of the orifice 651, the timing of starting the operation of the pump 8 and the operation of the tip retracting mechanism 6 can be adjusted.

The thin tube 65 is not limited to the one shown in the figure.
There may be more than one.

In such a chip retracting mechanism 6, when the fingertip 200 is brought into contact with the contact part 163 and the pump 8 is operated with the tip end opening 162 sealed, first, the inner cavity 52
(Including the inside of the chip 13) is decompressed, and the air in the variable volume chamber 631 flows through the orifice 651 into the lumen 5.
2 and the decompression of the variable volume chamber 631 is started.
Since the air passage resistance of the orifice 651 is high, the volume of the variable volume chamber 631 gradually decreases, and the housing 5 and the chip 13 attached thereto move gradually in the direction away from the fingertip 200.

Eventually, the base end 591 of the convex portion 59 and the concave portion 62
When the bottom surface of the housing 5 comes into contact with the housing 5, the movement of the housing 5 and the chip 13 mounted thereon toward the base end is stopped (see FIG. 8). Therefore, by adjusting the length of the protrusion 59 in the axial direction, the tip 13 can be prevented from being unnecessarily separated from the fingertip 200. That is, the chip 1 is formed by the convex portion 59 and the bottom surface of the concave portion 621 abutting thereon.
Means (moving distance defining means) for defining the moving distance (maximum retreat distance) from the third fingertip 200 is configured.

The separation distance between the chip 13 and the fingertip 200 (maximum retreat distance of the chip 13) is not particularly limited, but is preferably, for example, about 0.2 to 2.5 mm, and 0.5 to 2.5 mm. More preferably, it is about 1.5 mm. By setting the separation distance within the above range, a sufficient amount of blood can be secured more reliably and in a shorter time. In addition, it is possible to more reliably prevent the fingertip 200 from coming off the tip opening 162.

The tip retracting mechanism 6 operates following the operation of the pump 8. That is, the tip retracting mechanism 6
Reduces the pressure in the inner cavity 52 by the pump 8 and
After sucking the fingertip 200 at 62, the tip 13 is gradually retracted (moved) in the proximal direction. For this reason, the tip retreat mechanism 6 is used to
While maintaining 10 in a reduced pressure state, the tip 13 is
Can be separated from.

[0107] Such a chip retracting mechanism 6 is provided with a pump 8
It operates using the decompression force generated by. In other words, the pump (decompression means) 8 can be said to be one of the components of the chip retracting mechanism 6.

Further, since such a chip retreat mechanism 6 does not require the addition of another driving source, it is advantageous for reducing the size and weight of the component measuring device 1 and reducing the manufacturing cost.

Further, in this component measuring device 1, as shown in FIG. 6, when the fingertip 200 is pressed against the finger contact portion 3, the surface of the fingertip 200 comes into contact with the tip of the contact portion 163. Capillaries around the puncture site 210 are compressed by the tip of the part 163, but the puncture site 21 of the fingertip 200 is compressed.
Since the tip 13 can be separated from the fingertip 200 while maintaining the pressure 0 at a reduced pressure, the capillaries around the puncture site 210 that have been pressed by the tip of the contact portion 163 are opened, and the blood 220 is more The blood is sucked out of the puncture site 210 reliably and in a short time, and a sufficient and necessary blood volume for measuring the glucose amount can be secured.

The operating state of the chip retracting mechanism 6 (FIG. 8)
), The housing 5 moves in the proximal direction,
The seal ring 64 is in a compressed state. As described above, since the seal ring 64 is formed of an elastic body, the seal 5 urges the housing 5 in the distal direction in the state shown in FIG. Therefore, when the solenoid valve 26 is opened to release this depressurized state, the seal ring 64 returns to its original shape by its own elastic force, and moves the housing 5 toward the distal end (see FIGS. 9 and 10). At this time, the distal end of the flange 56 of the housing 5 comes into contact with the proximal end of the convex portion 611 of the main body 61, and further movement in the distal direction is restricted (see FIG. 10). That is, the housing 5 and the chip 13 attached thereto return to the position before the operation of the chip retracting mechanism 6.

Next, the operation of each part and the control operation of the control means when performing puncture, blood collection, expansion and blood sugar level measurement using the component measuring apparatus 1 will be described with reference to the flow charts shown in FIGS. 2 to 10 and FIG. This will be described with reference to FIG.

[1] First, the tip 13 is inserted into the fitting portion 53 of the housing 5 through the opening 212 of the housing 21, and the reduced diameter portion 143 of the puncture needle 14 is fitted into the needle holder 411 (FIG. 4).

Further, when the tip 13 is pushed in the proximal direction, the plunger 41 is pressed against the urging force of the coil spring 42.
Moves in the proximal direction. The locking portion 413 includes an elastic piece 412.
Is pressed by the resilient force of the above and is in contact with the inner peripheral surface of the inner cavity 52. When the locking portion 413 comes to the position of the opening 57, it is inserted into the opening 57 (see FIG. 4). Thereby, even if the pressing force in the proximal direction by the tip 13 is released, the locking portion 4
13 is locked in the opening 57, and movement of the plunger 41 in the distal direction is restricted. At this time, the coil spring 42 is in a compressed state. In this state, preparation for puncturing by the puncturing means 4 and preparation for blood (sample) collection are completed.

[2] Next, a power switch (not shown) is turned on. Thereby, each part of the component measuring device 1 is activated, and becomes in a measurable state. Note that the solenoid valve 26 is closed.

[3] Next, the fingertip (finger) 2
Press 0. Thereby, the contact portion 16 of the chip 13
The fingertip 200 is crimped to 3. At this time, the tip opening 162 is placed at the fingertip 2 so that air leakage is minimized.
00 (see FIG. 5).

[4] Next, the operation button 222 is pressed to puncture the surface of the fingertip 200 (step S101 in FIG. 12).

When the operation button 222 is pressed, the unlocking member 223 connected to the operation button 222 moves downward in FIG. As a result, the lock release member 223 comes into contact with the lock portion 413 and pushes it back toward the inner cavity 52. As a result, the engagement of the engagement portion 413 is released, and the plunger 41 moves in the distal direction by the elastic force of the compressed coil spring 42, the needle 141 projects from the distal opening 162, and punctures the surface of the fingertip 200. (See FIG. 6). Needle 1
Bleeding occurs from the puncture site 210 due to 41.

When the operation button 222 is pressed, the operation switch (not shown) of the pump 8 is turned on almost simultaneously.

[5] After the needle body 141 punctures the fingertip 200, the coil spring 43 pushes the plunger 41 back in the proximal direction. The plunger 41 stops at a position where the elastic force of the coil spring 42 and the elastic force of the coil spring 43 are balanced through the damping movement (see FIG. 7). At this time, the cutting edge of the needle 141 is housed in the tip 13. in this way,
The cutting edge of the needle 141 does not protrude from the distal end opening 162 except at the time of puncturing, so that it does not injure the skin or the like accidentally, can prevent infection, and is highly safe.

[6] When the operation switch of the pump 8 is turned on, the control means operates the pump 8 (FIG. 12).
Step S102).

That is, almost at the same time as the operation [4], the pump 8 operates, and the suction of the air in the lumen 52 of the housing 5 is started. As a result, the pressure of the lumen 52 (including the inside of the chip 13) is reduced, and the pressure is reduced.

At this time, the puncture site 210 of the fingertip 200 with the needle 141 is also in a reduced pressure state. However, in this state, the fingertip 200 located inside the contact portion 163 (tip opening 162) rises hill-like toward the inside of the chip 13, and the puncture site 210 where the tip of the contact portion 163 is in contact. In the surrounding area, the capillaries are compressed.

[7] Further, the lumen 5 by the pump 8
When the suction of 2 is continued, the air in the variable volume chamber 631 becomes
Through the orifice 651, the gas gradually flows into the lumen 52, and the volume of the variable volume chamber 631 gradually decreases.
As a result, the housing 5 and the chip 13 attached thereto move in the proximal direction, that is, the fingertip 200.
It gradually starts moving in the direction away from.

At this time, since the depressurized state of the lumen 52 and the puncture site 210 of the fingertip 200 is maintained, the fingertip 200 does not come off from the distal end opening 162. Further, even when the tip 13 moves in the direction away from the fingertip 200, the fingertip 200 does not move following the tip 13 because it is in contact with the finger rest 3. Therefore, the chip 13 is separated from the fingertip 200 without fail.

When the tip 13 is separated from the fingertip 200, the capillaries around the puncture site 210, which have been pressed by the tip of the contact portion 163, are gradually released, and blood 220 is sucked out of the puncture site 210. (See FIG. 8). That is, bleeding is promoted as compared with a case where the fingertip 200 and the chip 13 are not separated from each other, and a necessary blood volume can be secured in a short time.

The minimum pressure generated by the pump 8 is preferably, for example, about 100 to 400 mmHg.

Eventually, the base end 591 of the convex portion 59 and the concave portion 62
1 contacts the bottom surface. As a result, the movement of the housing 5 and the tip 13 attached thereto in the proximal direction is stopped. As described above, the chip 13 stops when it is separated from the fingertip 200 by an appropriate distance, so that the fingertip 200 does not come off from the distal end opening 162. Therefore, it is possible to more reliably prevent the blood 220 sucked from the puncture site 210 from scattering and contaminating the surroundings, and the safety is high.

As described above, in the component measuring device 1, the puncturing operation and the depressurizing operation are performed almost simultaneously by one pressing of the operation button 222, and the retracting operation of the chip 13 is performed by the depressurizing force of the pump 8. Is carried out using
Since the decompression releasing operation described later is also started automatically, the operability is extremely good.

[8] By the operation of [7], the puncture site 2
The blood 220 that has been raised in a granular manner on the blood 10 is sucked into the chip 13, and the blood introduction guide 166 formed inside the chip 13.
To the test paper 18 via the blood passage 19,
It is supplied to the center of the test paper 18 and developed radially (see FIG. 2).

As the blood 220 is supplied and spread on the test paper 18, glucose (a component to be measured) in the blood 220 reacts with the reagent carried on the test paper 18, and the test paper 18
Is colored according to the amount of glucose.

On the other hand, after executing the step S102 shown in FIG. 12, the control means 11 drives the measuring means 7 and monitors the coloration of the test paper 18 via the measuring means 7 (monitor).
Then, it is determined whether or not blood has been collected (step S103 in FIG. 12).

In step S103, if the voltage level of the signal input from the light receiving element 72 of the measuring means 7 exceeds a preset threshold value, it is determined that blood has been collected, and If the voltage level is below the threshold, it is determined that blood has not been collected.

The threshold value is sufficiently higher than the voltage level of the signal before the test paper 18 is colored, and
The value is set to a value sufficiently smaller than the voltage level of the signal when the color is displayed.

If it is determined in step S103 that no blood has been collected, it is determined whether or not the time is up (step S104 in FIG. 12).

If it is determined in step S104 that the time is not up, the process returns to step S102, and steps S102 and subsequent steps are executed again. If it is determined that the time is up, error processing is performed (see FIG. 12). Step S105).

In step S105, the pump 8 is stopped, the solenoid valve 26 is opened to release the reduced pressure state, and a display indicating an error (error display) is displayed on the display unit 12.

The operator (user) can grasp from the error display that the error is an error (there is a problem).

The operation when the electromagnetic valve 26 is opened will be described later in detail. If it is determined in step S103 that blood has been collected, the pump 8 is stopped (step S106 in FIG. 12).

Next, the solenoid valve 26 is opened to release the reduced pressure state (step S107 in FIG. 12).

When the solenoid valve 26 is opened, the tubes 82, 81
Outside air (atmosphere) flows into the lumen portion 52 (including inside the chip 13) and the puncture site 210 through the ventilation path 54, and the lumen portion 52 (including inside the chip 13) and the puncture site 210 become large. It returns to the atmospheric pressure (see FIG. 9).

The seal ring 64 returns to a substantially original shape by its own elastic force, and moves the housing 5 in the distal direction (see FIGS. 9 and 10). At this time, the distal end of the flange 56 of the housing 5 comes into contact with the proximal end of the convex portion 611 of the main body 61, and further movement in the distal direction is restricted (see FIG. 10).

When it is confirmed that the sense of suction around the puncture site 210 of the fingertip 200 has disappeared and the pressure has returned to the atmospheric pressure, the contact portion 163 of the chip 13 is separated from the fingertip 200.

[9] After executing step S107 shown in FIG. 12, the control means 11 measures the degree of coloration of the test paper 18 by the measurement means 7, performs an arithmetic process based on the obtained data, Correction such as correction calculation and hematocrit value correction calculation is performed to quantify the blood sugar level (step S108 in FIG. 12).

In this case, since the depressurized state of the lumen 52 (including the inside of the chip 13), that is, the depressurized state of the storage space for the test paper 18, has been released, the glucose (the component to be measured) in the blood 220 has been released. ) And the components in the atmosphere necessary for the reaction between the reagent carried on the test paper 18 are sufficiently supplied, whereby the blood glucose level can be accurately measured.

Next, the calculated blood sugar level is displayed on the display unit 1.
2 (step S109 in FIG. 12). Thereby, the blood sugar level can be grasped.

As described above, this component measuring device 1
According to the method, a sufficient and necessary amount of blood can be collected for measurement in a short time and the blood sugar level (the amount of a predetermined component in blood) can be accurately and reliably measured.

Further, since the test paper 18 is provided on the chip 13, puncturing, blood collection, development on the test paper 18, and measurement (quantification of components) can be continuously performed.
Blood glucose measurement (component measurement) can be performed easily and in a short time.

Further, the preparation operation at the time of use is easy, and therefore, it is advantageous also when the device is used regularly or repeatedly.

In addition, accidents such as accidental puncturing of the living body surface after puncturing once are prevented, and the safety is high. In addition, since the puncture needle 14 is not directly visible, fear of puncturing is reduced.

As described above, this component measuring device 1
It is suitable for use when the patient himself measures his own blood sugar level and the like.

The component measuring device 1 has a simple structure, is small and lightweight, is inexpensive, and is suitable for mass production.

Next, a second embodiment of the component measuring device of the present invention will be described. The component measuring device according to the second embodiment is different from the component measuring device 1 according to the first embodiment in the configuration of the decompression releasing unit.

FIG. 13 is a longitudinal sectional view showing a configuration example of a main part in the component measuring apparatus according to the second embodiment, and FIG.
It is a block diagram showing the circuit composition of the constituent measuring device of an embodiment.

Hereinafter, differences from the component measuring apparatus 1 of the above-described first embodiment will be mainly described, and description of the same items will be omitted. In the following description, FIG.
3 is referred to as “proximal end” and the left side as “distal end”.

As shown in FIGS. 13 and 14, in the component measuring device 1 of the second embodiment, a thin tube 83 is used instead of the electromagnetic valve 26 of the component measuring device 1 of the first embodiment.
Is provided.

The thin tube 83 is formed of a cylindrical member, and has an orifice (flow path) 831 formed therein. The thin tube 83 is joined (connected) to the end of the tube 82, and the tip of the thin tube 83 (orifice 831) is open to the outside of the main body 21.

Since the orifice 831 of the thin tube 83 has a small diameter, it has a high air passage resistance. The diameter of the orifice 831 is not particularly limited.
It is preferably about 0.3 mm. The length of the orifice 831 is not particularly limited, but is 5 to 15 mm.
It is preferred to be on the order of magnitude. By setting the diameter of the orifice 831 within the above range, necessary and sufficient air passage (flow) resistance can be obtained.

The tubes (flow paths) 81 and 82 and the thin tube 83 constitute a pressure reduction releasing means.

The number of the thin tubes 83 is not limited to that shown in the figure, and the number of the thin tubes 83 and the number of orifices may be plural if necessary.

Next, the operation of the component measuring device 1 will be described with reference to the flowchart shown in FIG. 12, focusing on the differences from the component measuring device 1 of the first embodiment described above.

First, steps S101 to S106 shown in FIG. 12 are almost the same as those of the component measuring device 1 of the first embodiment described above.

In this case, in the component measuring device 1, the flow rate of the air sucked by the operation of the pump 8 is larger (larger) than the flow rate of the outside air (atmosphere) flowing from the orifice 831 of the thin tube 83. Pump 8 in S102
Is activated, the suction of the air in the lumen 52 of the housing 5 is started, whereby the pressure of the lumen 52 (including the inside of the chip 13) is reduced, and the pressure is reduced.

In the component measuring apparatus 1, when the pump 8 is stopped in step S106, the lumen 52 (including the inside of the chip 13) is passed through the orifice 831 of the thin tube 83, the tubes 82 and 81, and the air passage 54. Then, outside air (atmosphere) flows into the puncture site 210, and the reduced pressure state of the lumen 52 (including the inside of the chip 13) and the puncture site 210 is released (Step S107 in FIG. 12). That is, the lumen portion 52 (including the inside of the chip 13) and the puncture site 210
Returns to atmospheric pressure.

Steps S108 and S109 shown in FIG. 12 are the same as those of the component measuring device 1 of the first embodiment described above.

According to the component measuring device 1, the same effects as those of the component measuring device 1 of the first embodiment can be obtained.

The component measuring apparatus of the present invention has been described based on the illustrated embodiments. However, the present invention is not limited to these embodiments. For example, the configuration of each section exhibits the same function. Any configuration that can be obtained can be substituted.

In the above embodiment, glucose (blood sugar level) was described as a representative component to be measured. However, in the present invention, the component to be measured is not limited to this. For example, protein, cholesterol, Inorganic ions such as uric acid, creatinine, alcohol, and sodium may be used.

In the above-described embodiment, the blood sampling detecting means for detecting the blood sampling and the measuring means for measuring the amount of the predetermined component in the blood (in this embodiment, this means is referred to as “measuring means”). However, in the present invention, the blood sampling detecting means and the measuring means may be separately provided.

In the above embodiment, means for optically detecting blood sampling is used as the blood sampling detecting means. However, the present invention is not limited to this.
Means for electrically detecting may be used.

In the present invention, when the blood collection detecting means for optically detecting the blood collection is used, the color (coloring) of the test paper is detected by the reaction between the components in the blood and the reagent as described above. In addition to the above, for example, a device that detects the introduction of blood into a blood passage (blood passage) that supplies blood to the test paper of the chip may be used.

To detect the introduction of blood into the blood passage, for example, at least the vicinity of the blood passage of the chip is formed of a light-transmissive (transparent) member, and the blood collection detecting means The blood passage is irradiated with light, the reflected light or transmitted light is received, photoelectrically converted, and the control means monitors the output voltage from the blood collection detection means. When blood is introduced into the blood passage, the color of the site changes to substantially red-black, whereby the amount of reflected light or transmitted light from the site changes, and the output voltage from the blood collection detection unit changes. Changes, the detection of the change in the output voltage (light amount) is regarded as the detection of blood sampling.

The blood collection detecting means for electrically detecting the collection of blood includes, for example, a sensor (electrode) for detecting (measuring) the impedance of a blood passage or the like of a chip, a biosensor, and the like.

When the biosensor is used, for example, when blood is introduced into the blood passage, the output current from the biosensor changes. By detecting the change in the output current (current value), Detection of blood sampling.

When a sensor for detecting the impedance is used, for example, when blood is introduced into the blood passage, the impedance between the electrodes of the sensor changes. Detection of blood sampling.

Further, the component measuring device of the present invention optically measures (colorimetrically measures) the color intensity of the test paper colored by the reaction between the components in blood and the reagent as described above, and converts the measured value into a measured value. The present invention is not limited to the conversion and display. For example, a potential change generated according to the amount of the component in the sample may be electrically measured, converted to a measured value, and displayed.

Further, in the above-described embodiment, the reduced pressure state is released before the measurement, but in the present invention, the reduced pressure state may be relaxed before the measurement.

In the present invention, the operations of the pressure reducing means and the tip retreating mechanism may be started manually or automatically, respectively. In the latter case, a sensor or the like configured to magnetically sense the movement of the puncture needle in the tip direction at the time of puncturing a fingertip is installed near the side of the fitting portion of the housing, and information of this sensor is provided. , The pressure reducing means and the chip retracting mechanism can be operated.

[0178]

As described above, according to the present invention, it is possible to provide a component measuring apparatus capable of accurately and reliably measuring a predetermined component in blood in a short time.

Further, since the test paper is provided on the chip, puncturing, blood collection, development on the test paper, and measurement (quantification of components) can be continuously performed, and component measurement can be performed easily and in a short time. Can be done in time.

Further, since the preparation operation at the time of use is easy, it is advantageous when the device is used regularly or repeatedly.

Further, accidents such as accidental puncturing of the living body surface after puncturing once are prevented, and the safety is high. Moreover, since the puncture needle is not directly visible, fear of puncturing is reduced.

As described above, the component measuring apparatus of the present invention is suitable for use when a patient himself / herself measures a blood sugar level or the like.

The component measuring apparatus of the present invention has a simple structure, is small, lightweight, inexpensive, and is suitable for mass production.

[Brief description of the drawings]

FIG. 1 is a perspective view schematically showing a first embodiment of a component measuring device of the present invention.

FIG. 2 is a longitudinal sectional view showing a configuration example of a chip used in the present invention.

FIG. 3 is a longitudinal sectional view showing a configuration example of a puncturing means and a housing containing the puncturing means of the component measuring device of the first embodiment (a state before a chip is mounted on the housing).

FIG. 4 is a longitudinal sectional view (with a chip mounted on the housing) showing a configuration example of a puncturing means and a housing containing the puncturing means of the component measuring device of the first embodiment.

FIG. 5 is a longitudinal sectional view showing a configuration example of a main part in the component measuring device according to the first embodiment (a state before operation of a puncturing means).

FIG. 6 is a vertical cross-sectional view showing a configuration example of a main part of the component measuring device according to the first embodiment (a state when the puncturing means is operated).

FIG. 7 is a vertical cross-sectional view showing a configuration example of a main part of the component measuring device according to the first embodiment (a state when the pressure reducing unit is operated).

FIG. 8 is a vertical cross-sectional view showing a configuration example of a main part of the component measuring device according to the first embodiment (a state in which a chip retracting mechanism is operated).

FIG. 9 is a vertical cross-sectional view showing a configuration example of a main part in the component measuring device according to the first embodiment (a state when the decompression releasing means is operated)
It is.

FIG. 10 is a longitudinal sectional view (final state) showing a configuration example of a main part in the component measuring device of the first embodiment.

FIG. 11 is a block diagram illustrating a circuit configuration of the component measuring device according to the first embodiment.

FIG. 12 is a flowchart showing a control operation (partially including an operation of an operator) of a control unit of the component measuring device of the first embodiment.

FIG. 13 is a longitudinal perspective view showing a main part of a component measuring device according to a second embodiment of the present invention.

FIG. 14 is a block diagram illustrating a circuit configuration of a component measurement device according to a second embodiment.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Component measuring apparatus 2 Main body 21 Housing 211 Wall part 212 Opening 22 Lid 221 Display window 222 Operation button 223 Lock release member 23 Storage space 3 Finger contact part 31 Finger contact surface 4 Puncturing means 41 Plunger 411 Needle holder 412 Elastic piece 413 Locking part 42 Coil spring 43 Coil spring 5 Housing 51 Wall part 511 Hole 52 Lumen part 53 Fitting part 54 Air passage 55 Seal ring 56 Flange 57 Opening 58 Seal member 59 Convex part 591 Base end 6 Chip retreating mechanism 61 Main part 611 Convex part 62 Wall part 621 Concave part 622 Surface 63 Lumen part 631 Variable volume chamber 64 Seal ring 65 Thin tube 651 Orifice 7 Measuring means 71 Light emitting element 72 Light receiving element 8 Pump 81, 82 Tube 83 Thin tube 831 Orifice 9 Battery 10 Circuit board 11 Control Means 1 Display unit 13 Tip 14 Puncture needle 141 Needle body 142 Hub 143 Reduced diameter part 15 First housing 151 Inner peripheral surface 152 Inner cavity 153 Wall 154 Hole 16 Second housing 161 Inner cavity 162 Tip opening 163 Contact part 164 Flange 165 Recess 166 Blood introduction guide 17 Test paper fixing part 18 Test paper 19 Blood passage 191 Passage opening 192 Passage opening 24 Amplifier 25 A / D converter 26 Solenoid valve 200 Fingertip 210 Puncturing site 220 Blood S101 to S109 Step

Claims (10)

[Claims] 1. A component measuring device which is used by mounting a tip provided with a puncture needle and a test paper, wherein: a finger contact portion for applying a finger to be punctured; and a finger applied to the finger contact portion for puncturing. Puncturing means for actuating the puncture needle so that the puncture needle and the test paper are stored together with a storage space for the puncture needle and the test paper. Measuring means for measuring the amount of a predetermined component in blood spread on paper; blood sampling detecting means for detecting blood sampling; and decompression releasing means for releasing or relaxing at least the decompressed state of the test paper storage space. When the blood collection is detected by the blood collection detection unit, the decompression release unit releases or relaxes at least the reduced pressure state of the storage space for the test paper, and then, Component measuring apparatus characterized by being configured to measure the amount of a given component in blood which is the taken by the constant unit. 2. The component measuring apparatus according to claim 1, wherein the measurement requires a predetermined component in the atmosphere. 3. The component measuring device according to claim 1, wherein the decompression releasing unit has a flow path that communicates the storage space with the outside, and a valve that opens and closes the flow path. 4. The decompression releasing means has a flow path communicating the storage space with the outside, and the flow path has, at least in part, a portion having a relatively high air passage resistance. 3. The component measuring device according to 1 or 2. 5. The component measuring device according to claim 1, wherein at least a part of said measuring means and at least a part of said blood sampling detecting means are also used mutually. 6. The component measuring device has a housing that holds the chip and houses the puncturing means, and the decompression means puts the storage space in the housing in a decompressed state. The component measuring device according to any one of the above. 7. The component measuring device according to claim 6, wherein the decompression releasing unit releases or reduces the decompressed state of the storage space in the housing. 8. The component measuring apparatus according to claim 1, wherein the operation of the puncturing means and the operation of the pressure reducing means can be started almost simultaneously. 9. The chip according to claim 1, wherein the chip has a contact portion that contacts a finger, and the tip is used so as to close an opening formed inside the contact portion with the finger. Component measuring device. 10. The component measuring device according to claim 1, wherein the test paper is a blood glucose measurement test paper.