JP2002020224A - Skin care preparation - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a skin care preparation having humectant effects with a slight load on the skin by formulating deep water subjected to an electrodialytic treatment. SOLUTION: This skin care preparation is characterized as comprising 5-80% of the deep water subjected to a desalinating treatment by an electrodialysis and containing <=0.20% of sodium ion and 0.05-0.15% of magnesium ion in the deep water.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an external preparation for skin containing deep water obtained by subjecting deep water to desalting treatment by electrodialysis, and more particularly, to a skin having a small load on the skin and having a moisturizing effect. For external preparations.

[0002]

2. Description of the Related Art Deep water, which is rich in inorganic salts, exhibits an excellent moisturizing effect when incorporated in an external preparation for skin.

[0003]

There are many skin external preparations containing deep water, but the deep water is still seawater. In addition, since deep water contains a salt content of 3% or more, some people rarely feel tingling or tingling when blended in a high concentration in an external preparation for skin. Moreover, when blended into emulsion-type preparations such as emulsions and creams,
In some cases, the emulsified particles may be destroyed, and it is difficult to mix them at a high concentration.

[0004]

Means for Solving the Problems The present inventors have made it possible to reduce the moisturizing effect inherent in deep water without impairing the moisturizing effect.
As a result of intensive research to obtain a skin external preparation that reduces the burden on the skin, the deep water is desalted by electrodialysis to further reduce the burden on the skin without impairing the moisturizing effect. And completed the present invention.

[0005] That is, the present invention is an external preparation for skin characterized by containing deep water that has been desalted by electrodialysis. The details will be described below.

[0006]

BEST MODE FOR CARRYING OUT THE INVENTION Deep water is seawater at a depth of 200 m or less, where sunlight cannot reach. The deep water is not particularly limited as long as it is deeper than 200 m, for example, deep water off Muroto Kochi, deep water off Namerikawa in Toyama, deep water off Itoman in Okinawa,
Deep water off Kumejima Island in Okinawa Prefecture and deep water off Shiretoko Rus in Hokkaido are known. As the electrodialysis apparatus, for example, an asilizer manufactured by Asahi Kasei Corporation is known. Electrodialysis is
This is a separation technique that utilizes the electrophoresis of ionic substances in a solution and the property that an ion exchange membrane selectively transmits cations and anions. In the present invention, deep water subjected to desalination treatment is obtained by selectively desalting monovalent ions, particularly sodium ions, using this electrodialysis apparatus. The amount of desalted monovalent sodium ions is not particularly limited, but is preferably 0.2% or less of deep water.

[0007] The content of deep water in the desalination treatment in the external preparation for skin of the present invention is not particularly limited, but is preferably 2 to 10.
100%, and more preferably 5 to 80%.
If the amount is less than 2%, the effect of the present invention may not be sufficiently exhibited, and even if the amount is more than 80%, no further increase in the effect may be observed.

The external preparation for skin of the present invention can be prepared by blending deep-treated water with various types of bases known as conventional external preparations for skin according to a conventional method.

The external preparation for skin of the present invention includes oily components, surfactants and the like, which are generally used as external skin preparation components, in addition to the above essential components, as long as the effects of the present invention are not impaired.
Components normally used in external preparations for skin, such as humectants, ultraviolet absorbers, chelating agents, pH adjusters, preservatives, thickeners, pigments, and fragrances can be appropriately compounded.

The external preparation for skin of the present invention can take any dosage form such as an oily preparation, an emulsion preparation, an aqueous preparation and the like, and is suitable as an external preparation for skin requiring a moisturizing effect.

The external preparation for skin of the present invention may contain an oily component in addition to the above essential components to further enhance the moisturizing effect. As the oily component, any known oily substances for external preparations for skin, such as oils and fats, waxes, hydrocarbon oils, esters, and silicone oil, may be used.
Jojoba oil, glycerin trioctanoate, glycerin triisopalmitate and the like. Solid oils and fats include palm oil, hardened tallow, hardened oil, hardened castor oil and the like. Examples of waxes include beeswax, candelilla wax, carnauba wax, lanolin, and liquid lanolin. Examples of the hydrocarbon oil include liquid paraffin, squalane, paraffin, ceresin, vaseline, and microcrystalline wax. As ester oils, isopropyl myristate,
And octyldodecyl myristate. Examples of the silicone oil include chain polysiloxanes such as dimethylpolysiloxane, methylphenylpolysiloxane and methylhydrogenpolysiloxane, and cyclic polysiloxanes such as decamethylpolysiloxane.

As the surfactant, for example, anionic,
Any of cationic, amphoteric, nonionic natural and synthetic surfactants can be blended. These surfactants act as emulsifying and solubilizing agents for oily components.

The water-soluble components include 1,3-butylene glycol, ethylene glycol, glycerin, diglycerin, and the like for the purpose of usability, homogenous stabilization, viscosity adjustment, and the like.
Polyhydric alcohols such as propylene glycol, dipropylene glycol, polyethylene glycol, polyglycerin, and polypropylene glycol, and water-soluble polymers such as sodium alginate, xanthan gum, methylcellulose, hydroxypropylcellulose, carboxymethylcellulose, carboxyvinyl polymers, polyvinylpyrrolidone, and gelatin Can be used.

The external preparation for skin of the present invention is emulsified by blending an oily component and a water-soluble component in addition to the transparent or translucent composition prepared with the above-mentioned components, and emulsified into a milky or creamy form. be able to.

[0015]

Next, the effects of the present invention will be described in more detail with reference to Reference Examples, Experimental Examples and Examples, but the present invention is not limited thereto.

(Reference Example 1) Deep water desalination treatment off Kumejima, Okinawa Prefecture In a sea area of 2,200 m off Kumejima, Okinawa Prefecture, a depth of 600
m was used as deep water. Deep water off the coast of Kumejima, Okinawa Prefecture was subjected to desalting treatment using an electrodialyzer asilizer manufactured by Asahi Kasei Corporation. As shown in Table 1, deep water off Kumejima, Okinawa Prefecture, contains abundant sodium ions compared to deep water subjected to desalination, but divalent ions such as magnesium ions and calcium ions
It was almost the same.

[0017]

[Table 1]

(Water Retention Test) Since deep water contains abundant minerals, it is considered that a remarkable moisturizing effect can be expected as compared with purified water. Therefore, the following water retention test was performed. Dried pork skin (Aroask manufactured by Taiho Pharmaceutical Co., Ltd.) is cut into strips of about 50 mm x 10 mm, and the deep water off Kumejima, the surface water off Kumejima, Okinawa, and the deep seawater off Kumejima, Okinawa, respectively. It was immersed in water and purified water for 20 minutes to make the amount of permeated water saturated. After wiping off the moisture on the sample surface, the sample was dried in a constant temperature oven at 37 ° C. and a humidity of 22%.
After 10 minutes and 30 minutes, the weight was measured, and the water content was calculated. The results are shown in Table 2 with the residual water content after drying expressed as a percentage, with the saturated water content before drying being 100.
(5 samples)

[0019]

[Table 2] A: Deep water off Kumejima, Okinawa B: Surface water off Kumejima, Okinawa C: Desalination deepwater off Kumejima, Okinawa D: Purified water

From the results in Table 2, it can be seen that the deep water off Kumejima, Okinawa Prefecture and the desalinated deep water off Kumejima, Okinawa have higher residual rates than the surface water off Okinawa, Kumajima and purified water, and the evaporation of water. It can be seen that the water retention effect is excellent.

Reference Example 2 Deep water desalination treatment off Shiretoko-Rusu, Hokkaido In a sea area of 1200 m off Shiretoko-Rasu, Hokkaido, a depth of 3
Seawater sampled from 00m was used as deep water. Deep water off the coast of Shiretoko, Hokkaido, was desalted using an electrodialyzer Ashirazer manufactured by Asahi Kasei Corporation. As shown in Table 3, deep sea water off Shiretoko Rusu in Hokkaido has an extremely low sodium ion content as compared with deep seawater subjected to desalination.
However, divalent ions such as magnesium ions and calcium ions contained almost the same amount.

[0022]

[Table 3]

The following are experimental examples of the present invention, but the present invention is not limited to these experimental examples.

Skin external preparations formulated as shown in Tables 4 and 5 were prepared, and their moisturizing effects were evaluated by the following test methods.

According to a questionnaire survey in advance, 10 persons each were selected as test subjects who suffer from bulkiness due to dry skin. The subjects were given an appropriate amount of skin cosmetics daily for 2 weeks at the part where the above symptoms were worrisome, and evaluated on a 5-point scale according to the following criteria. Tables 4 and 5 show the average scores. 5: Significant effect. 4: Very effective. 3: There is some effect. 2: Almost no effect. 1: No effect.

Experimental Example 1 Lotion A lotion having the composition shown in Table 4 was prepared and its moisturizing effect was examined.

[0027]

[Table 4] * Deep water desalination off the coast of Shiretoko, Hokkaido: Sodium ion concentration 0.01% Magnesium ion concentration 0.08%

From the results shown in Table 4, it can be seen that the skin external preparation of the present invention, which is a deep-sea water subjected to desalination off the coast of Shiretoko-Rusu in Hokkaido, has an excellent moisturizing effect at 5 to 100%.

Experimental Example 2 Lotion A lotion having the composition shown in Table 5 was prepared and its moisturizing effect was examined.

[0030]

[Table 5] * Deep water desalination off Kumejima, Okinawa Prefecture: sodium ion concentration 0.008% magnesium ion concentration 0.09%

From the results shown in Table 5, it can be seen that the skin external preparation of the present invention, which is a deep water desalinated off Kumejima Island in Okinawa, has an excellent moisturizing effect in the range of 5 to 80%.

Experimental Example 3 Cream A cream having the composition shown in Table 6 was prepared and its moisturizing effect was examined.

[0033]

[Table 6] * Deep water desalination off Kumejima, Okinawa: Sodium ion concentration 0.08% Magnesium ion concentration 0.06%

(Preparation method) A: Components 1 to 6 are mixed and heated to 80 ° C. B: Heat components 7-8 and maintain at 85 ° C. C: B is added to A, emulsified and mixed, and then cooled. D: Component 9 was added and mixed at 60 ° C, and cooled to 30 ° C to obtain a cream.

(Test Method) Twenty people aged 35 to 45 years old suffering from dry skin were taken as panels, and the skin condition before the start of the test was photographed with a microskin scope camera, and the score was obtained according to the following criteria. In the test, the test cream was applied twice a day, in the morning and at night, for 7 days, and after 1, 3, 5, and 7 days, the skin condition score was determined as described above. The scores were averaged to evaluate the moisturizing effect.

(Skin condition score) (Score) (State) 1 Skin groove of skin is unclear and exfoliation of keratin is recognized. 2 Skin crevices are slightly unclear and keratin peeling is slightly observed. 3 Skin sulcus is recognized and there is no exfoliation of keratin. 4 Skin sulcus is recognized and slightly reticulated. 5 Skin crevices are clearly recognized and have a beautiful mesh shape. The results obtained by the above evaluation method are also shown in Table 6.

As is evident from the results in Table 6, the creams containing the deep seawater desalinated off Kumejima, Okinawa, according to the present invention have a high moisturizing effect when applied to the skin.

Experimental Example 4 Lotion A lotion having the composition shown in Table 7 was prepared, and the presence or absence of burning and tingling upon application was examined.

[0039]

[Table 7] * Deep water desalination off Kumejima, Okinawa Prefecture: sodium ion concentration 0.04% magnesium ion concentration 0.11%

An appropriate amount of the lotion 16 shown in Table 7 is applied to the face. I noticed burning and tingling at the time of application 2
0 subjects (the following criteria: average 4.4) were set as subjects. Subjects were applied with the lotion 17 continuously for one week in the morning and evening, and a questionnaire survey was conducted to determine whether they felt burning and tingling when applied. The questionnaire was evaluated on a 5-point scale based on the following criteria. 5: The burning and tingling sensations are remarkably felt. 4: A considerable tingling and tingling sensation is felt. 3: A slight tingling or tingling sensation is felt. 2: There is almost no tingling or tingling sensation. 1: There is no tingling or tingling sensation at all.

The average of the questionnaire results of 20 subjects who applied the lotion 17 continuously for one week in the morning and evening was 2.2. Desalted deep water obtained by electrodialysis of deep water off Kumejima off Okinawa Prefecture has significantly less tingling and tingling sensation than deep water, and it is considered that the burden on the skin is small.

The present invention will be described in more detail with reference to examples.
The present invention is not limited to the embodiments.

Example 1 Lotion Component% 1. Desalination deep water off Kumejima, Okinawa 80.0 2. Denatured alcohol 10.0 3. Methylparaben 0.3 4.1, 3 butylene glycol 5.0 5.0. Total volume of purified water 100.0 * Deep water desalination off Kumejima, Okinawa Prefecture: sodium ion concentration 0.01% magnesium ion concentration 0.12%

(Preparation method) Component 3 was dissolved in Component 2 and Component 1 was dissolved.
To be added. The remaining components 4 and 5 were added and mixed with stirring to obtain a lotion. Example 1 had an excellent moisturizing effect and the stability of the preparation was also excellent.

Example 2 Emulsion Ingredient% A POE (20) behenyl alcohol 2.4 Sorbitan monopalmitate 1.6 Isostearyl palmitate 5.0 Isopropyl myristate 3.0 Lanolin 1.5 Stearic acid 1.5 Cetanol 1. 0 Milwax 2.0 Paraffin wax 2.0 Methyl paraben 0.2 B Desalination deep water off the coast of Namerikawa, Toyama Prefecture 10.0 Carboxyvinyl polymer 0.2 Aminomethylpropanediol 0.1 1, 3 Butylene glycol 10.0 Purified water 100.0 C Fragrance 0.1 * Desalination deep water off the coast of Namerikawa, Toyama Prefecture: Sodium ion concentration 0.007% Magnesium ion concentration 0.07%

(Preparation method) A is heated to 80 ° C. to dissolve it.
After dispersion of B, the temperature is raised to 85 ° C. Add B to A and stir and mix. After cooling, C is added at 70 ° C.
After cooling to 30 ° C., an emulsion was obtained. Example 2 had an excellent moisturizing effect and the stability of the preparation was also excellent.

Example 3 Cream Ingredient% A PEG monostearate (40EO) 3.0 Sorbitan monopalmitate 1.0 Cetyl isooctanoate 10.0 Isopropyl myristate 5.0 Liquid paraffin (# 70) 5.0 Stearic acid 5.0 Cetanol 3.0 Paraffin wax 3.0 Lanolin 2.0 Methyl paraben 0.3 B Desalination deep water off Kumejima, Okinawa 20.0 Bentonite 0.5 Glycerin 5.0 Total amount with purified water 100.0 C Perfume 0.2 * Deep water desalination off Kumejima, Okinawa Prefecture: sodium ion concentration 0.007% magnesium ion concentration 0.11%

(Preparation method) A is heated to 80 ° C. and dissolved.
After dispersion of B, the temperature is raised to 85 ° C. Add B to A and stir and mix. After cooling, C is added at 70 ° C.
Cooling to 30 ° C. gave a cream. Example 3 had an excellent moisturizing effect and the stability of the preparation was also excellent.

Example 4 Gel Ingredient% Desalination deep water off Kumejima, Okinawa 5.0 2. The total amount is 100.0 with purified water. Carboxyvinyl polymer 0.25 4. Potassium hydroxide 0.15. Glycerin 5.0 6. Denatured alcohol 5.0 7. Methylparaben 10.0 * Deep water desalination off Kumejima, Okinawa Prefecture: sodium ion concentration 0.009% magnesium ion concentration 0.10%

(Preparation method) Component 7 is dissolved in Component 6. Component 3 is dispersed in Components 1 and 2, and Component 4 is added. Thereafter, the remaining components were added and mixed with stirring to obtain a gel. Example 4
Was excellent in moisturizing effect when applied to the skin, and had no burning or tingling sensation.

 ──────────────────────────────────────────────────続 き Continuing on the front page (72) Kunihiro Miyamoto 2-7 Torimicho, Nishi-ku, Nagoya-shi, Aichi Japan Inside of Menard Cosmetics Co., Ltd. (72) Satoru Nakata 2- Torimicho, Nishi-ku, Nagoya-shi, Aichi 7 Japan Term Cosmetics Co., Ltd. F-term (reference) 4C083 AA082 AB032 AB051 AB052 AC012 AC022 AC072 AC102 AC122 AC182 AC242 AC352 AC402 AC442 AC482 AC542 AD092 AD512 AD532 BB51 CC04 CC05 DD31 DD41

Claims (3)

[Claims] 1. An external preparation for skin comprising deep water which has been subjected to a desalination treatment by electrodialysis. 2. Deep water which has been subjected to desalination treatment by electrodialysis contains deep water in which sodium ion is 0.20% or less and magnesium ion is 0.05 to 0.15%. External preparation for skin. 3. The external preparation for skin according to claim 1, wherein the blending amount of the deep water subjected to the desalting treatment by the electrodialysis device is 5 to 80%.