JP2001278768A - Skin care preparation - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a skin care preparation which has a skin moisture-retaining effect, a skin moisture retention-persisting effect, and an anti-stinging effect. SOLUTION: This skin care preparation contains sea deep water collected from the offshore of Kumejima island in Okinawa prefecture.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an external preparation for skin containing deep water off Kumejima Island, Okinawa, and more specifically, a skin having excellent moisturizing effect, long lasting moisturizing effect and anti-stinging effect. For external preparations.

[0002]

2. Description of the Related Art The stratum corneum of normal skin usually has a thickness of 10 to 20%.
% Moisture, and retains its elasticity, flexibility and protection function. However, when it becomes 10% or less due to changes in the external environment such as temperature and humidity, it becomes a state called dry skin. It is known that the skin loses its elasticity and protective function and causes various troubles. Therefore, for the purpose of repairing or preventing such dry skin, a moisturizing agent and the like have been conventionally added to a skin external preparation.

[0003]

However, these moisturizing agents do not penetrate into the stratum corneum in normal skin, but remain on the skin, so that the moisturizing effect is weak and the effect is temporary. There was a drawback that it was a thing.

[0004]

DISCLOSURE OF THE INVENTION The present inventors have conducted intensive studies to obtain an external preparation for skin having a moisturizing effect, a sustained high moisturizing effect and an anti-stinging effect, and as a result, have found that off Kumejima off Okinawa Prefecture It has been found that the addition of deep water increases the moisturizing effect and the persistence of the effect, and furthermore, has an anti-stinging effect, thereby completing the present invention.
In the present invention, stinging is a general term for pain such as transient tingling, tingling, tingling, and ginseng caused by application of an external preparation for skin.

[0005] That is, the present invention is an external preparation for skin characterized by containing deep water off Kumejima, Okinawa Prefecture. Less than,
This will be described in detail.

[0006]

BEST MODE FOR CARRYING OUT THE INVENTION The deep water off Kumejima Island in Okinawa Prefecture of the present invention is offshore 1500 which is taken off by a water intake device installed at a deep seawater research facility in northern Kumejima, about 100 km west of Okinawa Main Island. ~ 3000m, preferably 2000 ~
2500 m, and the water intake depth is 200-700 m, preferably 550-650 m.

[0007] The content of deep water off Kumejima in Okinawa in the external preparation for skin of the present invention is not particularly limited, but is preferably 5 to 80%, more preferably 10 to 50%.
It is. If the amount is less than 5%, the effects of the present invention will not be sufficiently exhibited, and even if the amount exceeds 80%, no further increase in the effect will be observed.

The external preparation for skin of the present invention can be prepared by blending the deep water off Kumejima Island in Okinawa with various types of bases known as ordinary external preparations for skin in accordance with a conventional method.

The external preparation for skin of the present invention includes oily components, surfactants, humectants, and ultraviolet rays which are generally used as external preparation components in addition to the above essential components as long as the effects of the present invention are not impaired. Absorbent, chelating agent, pH adjuster, preservative,
Components normally used in external preparations for skin, such as thickeners, pigments, and fragrances, can be appropriately blended.

The external preparation for skin of the present invention can take any dosage form such as an oily preparation, an emulsion preparation, an aqueous preparation and the like, and is suitable as an external preparation for skin requiring a moisturizing effect such as rough skin.

The external preparation for skin of the present invention may contain an oily component in addition to the above essential components to further enhance the moisturizing effect. As the oily component, any known oily substances for external preparations for skin, such as oils and fats, waxes, hydrocarbon oils, esters, and silicone oil, may be used.
Jojoba oil, glycerin trioctanoate, glycerin triisopalmitate and the like. Solid oils and fats include palm oil, hardened tallow, hardened oil, hardened castor oil and the like. Examples of waxes include beeswax, candelilla wax, carnauba wax, lanolin, and liquid lanolin. Examples of the hydrocarbon oil include liquid paraffin, squalane, paraffin, ceresin, vaseline, and microcrystalline wax. As ester oils, isopropyl myristate,
And octyldodecyl myristate. Examples of the silicone oil include chain polysiloxanes such as dimethylpolysiloxane, methylphenylpolysiloxane and methylhydrogenpolysiloxane, and cyclic polysiloxanes such as decamethylpolysiloxane.

As the surfactant, for example, anionic,
Any of cationic, amphoteric, nonionic natural and synthetic surfactants can be blended. These surfactants act as emulsifying and solubilizing agents for the oil component, and the amount of the surfactant is preferably 0 to 30% of the whole composition.

The water-soluble components include 1,3-butylene glycol, ethylene glycol, glycerin, diglycerin, and the like for the purpose of usability, homogenous stabilization, viscosity adjustment, and the like.
Polyhydric alcohols such as propylene glycol, dipropylene glycol, polyethylene glycol, polyglycerin, and polypropylene glycol, and water-soluble polymers such as sodium alginate, xanthan gum, methylcellulose, hydroxypropylcellulose, carboxymethylcellulose, carboxyvinyl polymers, polyvinylpyrrolidone, and gelatin Can be used.

The external preparation for skin of the present invention is emulsified by blending an oily component and a water-soluble component in addition to the transparent or translucent composition prepared with the above-mentioned components, and emulsified into a milky or creamy form. be able to.

[0015]

Next, the effects of the present invention will be described in more detail with reference to Reference Examples, Experimental Examples and Examples, but the present invention is not limited thereto.

(Reference Example) Deep water off Kumejima, Okinawa Prefecture In a sea area of 2,200 m off Kumejima, Okinawa Prefecture, a depth of 600
m was used as deep water. As shown in Table 1 below, the deep water was rich in nutrients as compared with the surface water. In addition, the deep water off the coast of Namerikawa in Toyama Prefecture and the deep water off the coast of Muroto in Kochi Prefecture are also shown for comparison, but the water quality and nutrient composition are completely different.

[0017]

[Table 1]

(Water retention test) Deep water off Kumejima, Okinawa Prefecture,
It is thought that a remarkable moisturizing effect can be expected as compared with surface water and purified water. Therefore, the following water retention test was performed. Cut dry pork skin (Aroask manufactured by Taiho Pharmaceutical Co., Ltd.) into strips of about 50 mm x 10 mm, and immerse them in deep water off Kumejima, Okinawa, surface water off Kumejima, and purified water for 20 minutes. The volume was saturated. After wiping off the moisture on the sample surface, the sample was dried in a constant temperature dryer at 37 ° C. and a humidity of 22%, and after 10 minutes and 30 minutes, the weight was measured to calculate the moisture content. The results are expressed as a percentage of the residual water content after drying, with the saturated water content before drying being 100, and Table 2
It was shown to. (Number of samples: 5) In addition, a water retention test was performed for the deep water off the coast of Namerikawa in Toyama Prefecture for comparison.

[0019]

[Table 2]

From the results in Table 2, it can be seen that the deep water off Kumejima, Okinawa Prefecture has a higher residual rate than the surface water off Kumejima, Okinawa Prefecture, and the deepwater off Namerikawa, Toyama Prefecture. It turns out that the effect is also excellent.

Examples of the present invention will be described below, but the present invention is not limited to these examples.

Skin external preparations formulated as shown in Tables 3 and 4 were prepared, and the moisturizing effect and the moisturizing sustaining effect were evaluated by the following test methods.

According to a questionnaire survey in advance, 10 persons were selected as subjects who were worried about bulkiness due to dry skin. The subjects were given an appropriate amount of skin cosmetics daily for 2 weeks at the part where the above symptoms were worrisome, and evaluated on a 5-point scale according to the following criteria. Tables 3 and 4 show the average scores. 5: Significant effect. 4: Very effective. 3: There is some effect. 2: Almost no effect. 1: No effect.

Experimental Example 1 Lotion A lotion having the composition shown in Table 3 was prepared, and its moisturizing effect and sustaining effect were examined.

[0025]

[Table 3]

From the results shown in Table 3, it can be seen that the skin external preparation of the present invention, which is deep water off Kumejima Island in Okinawa Prefecture, has excellent moisturizing effect and moisturizing sustaining effect at 5 to 80%.

Experimental Example 2 Lotion A lotion having the composition shown in Table 4 was prepared, and its moisturizing effect and sustaining effect were examined.

[0028]

[Table 4]

From the results shown in Table 4, it can be seen that the skin external preparation of the present invention, the deep water off Kumejima off Okinawa, has an excellent moisturizing effect and a moisturizing sustaining effect in the range of 5 to 80%.

Experimental Example 3 Cream A cream having the composition shown in Table 5 was prepared, and its moisturizing effect and moisturizing sustaining effect were examined.

[0031]

[Table 5]

(Preparation method) A: Components 1 to 6 are mixed and heated to 80 ° C. B: Heat components 7-8 and maintain at 85 ° C. C: B is added to A, emulsified and mixed, and then cooled. D: Component 9 was added and mixed at 60 ° C, and cooled to 30 ° C to obtain a cream.

(Test Method) Twenty people aged 35 to 45 years old suffering from dry skin were used as panels, and the skin condition before the start of the test was photographed with a microskin scope camera, and the score was obtained according to the following criteria. In the test, the test cream was applied twice a day, in the morning and at night, for 7 days, and after 1, 3, 5, and 7 days, the skin condition score was determined as described above. The scores were averaged to evaluate the moisturizing effect.

(Skin Condition Score) (Score) (State) 1 Skin groove of skin is unclear and exfoliation of keratin is recognized. 2 Skin sulcus is slightly unclear and keratin peeling is slightly observed. 3 Skin sulcus is recognized and there is no exfoliation of keratin. 4 Skin sulcus is recognized and slightly reticulated. 5 Skin crevices are clearly recognized and have a beautiful mesh shape. Table 5 also shows the results obtained by the above evaluation method.

As is evident from the results in Table 5, the creams containing the deep water off Kumejima, Okinawa Prefecture according to the present invention have a high moisturizing effect when applied to the skin.

(Anti-Stinging Effect) Stinging-inducing substances include preservatives such as methyl parahydroxybenzoate, phenoxyethanol, citric acid and lactic acid, and ethanol. In order to examine the anti-stinging action of deep water, a stinging test was carried out for stinger against methyl parahydroxybenzoate as a preservative and citric acid as an acid.

Experimental Example 4 Anti-Stinging Test 1 A total of 13 subjects, 8 males and 5 females, previously selected as stinger for methyl parahydroxybenzoate (hereinafter abbreviated as methylparaben) were used as subjects.
The test subjects wash their faces with a facial cleanser before the start of the test, rest for about 30 minutes in an artificial weather chamber (room temperature set at 24 ° C., humidity 50%), and then place them in a fixed area (about 4 cm × 5 cm) on one cheek. The test substance was uniformly applied in an amount of 0.2 ml. As test substances, deep water off Kumejima, Okinawa, distilled water (control substance for deep water), methylparaben (a stinging inducing substance), and carboxymethylcellulose (for preparing a solvent) were used. The application concentration was 1% solution of carboxymethylcellulose [hereinafter referred to as deep water (C
MC), abbreviated as distilled water (CMC)], and used as a solvent for methylparaben, a stinging-inducing substance. Methyl paraben was adjusted to a concentration of 0.3%.

(Judgment method) Stinging feeling induced 5 minutes after application was evaluated by self-report according to the evaluation criteria shown in Table 6. From these results, when two or more evaluation points were recognized, it was judged that there was a feeling of stinging.

[Table 6]

(Results) The results of the stinging test are shown in Table 7. As a result, one subject M is in deep water (CM
Because of the feeling of irritation to C), the anti-stinging effect of deep water off Kumejima, Okinawa Prefecture was evaluated for the remaining 12 persons who did not show irritation to the solvent. Eleven of the twelve subjects complained of stinging to methylparaben prepared using distilled water (CMC). This 11
Eight of the five subjects did not complain of stinging to methylparaben prepared using deep water (CMC). These results suggest that deep water off Kumejima Island, Okinawa Prefecture, suppresses the stinging effect induced by methylparaben.

[0040]

[Table 7]

Experimental Example 5 Anti-Stinging Test 2 A total of 10 subjects, 5 men and 5 women, previously selected as stingers for lactic acid were used as subjects. The test subjects wash their faces with a facial cleanser before the start of the test, rest for about 30 minutes in an artificial weather chamber (room temperature set at 24 ° C., humidity 50%), and then place them in a fixed area (about 4 cm × 5 cm) on one cheek. The test substance was uniformly applied in an amount of 0.2 ml. The test substances used were deep water off Kumejima, Okinawa Prefecture, distilled water (control substance for deep water), lactic acid (a stinging inducing substance), and carboxymethylcellulose (for solvent preparation). The applied concentration is 1% solution of carboxymethylcellulose (hereinafter abbreviated as deep water (CMC) and distilled water (CMC)) using deep water off Kumejima in Okinawa and distilled water, respectively, and is a stinging-inducing substance. Used as a solvent for lactic acid. Lactic acid is 10.0%
The concentration was adjusted.

(Determination method) Stinging feeling induced for 5 minutes after application was evaluated by self-report according to the evaluation criteria shown in Table 6. From these results, when two or more evaluation points were recognized, it was judged that there was a feeling of stinging.

(Results) Table 8 shows the results of the stinging test. As a result, 9 out of 10 subjects
The lactic acid prepared using (CMC) exhibited a feeling of stinging. Eight of the nine subjects did not complain of stinging to lactic acid prepared using deep water (CMC). These results suggest that deep water off Kumejima Island in Okinawa Prefecture suppresses the stinging effect induced by lactic acid.

[0044]

[Table 8]

The present invention will be described in more detail with reference to Examples.
The present invention is not limited to the embodiments.

Example 1 Lotion Component% 1. Deep water off Kumejima Island, Okinawa 20.0 2. Denatured alcohol 10.0 3. Methylparaben 0.3 4.1, 3 butylene glycol 5.0 5.0. 100.0 total with purified water

(Preparation method) Component 3 was dissolved in Component 2 and Component 1 was dissolved.
To be added. The remaining components 4 and 5 were added and mixed with stirring to obtain a lotion. Example 1 had an excellent moisturizing effect and an excellent effect of maintaining the moisturizing effect.

Example 2 Emulsion Ingredient% A POE (20) behenyl alcohol 2.4 Sorbitan monopalmitate 1.6 Isostearyl palmitate 5.0 Isopropyl myristate 3.0 Lanolin 1.5 Stearic acid 1.5 Cetanol 1. 0 Milwax 2.0 Paraffin wax 2.0 Methyl paraben 0.2 B Deep water off Kumejima, Okinawa Prefecture 10.0 Carboxyvinyl polymer 0.2 Aminomethylpropanediol 0.1 1, 3 Butylene glycol 10.0 Total amount with purified water 100.0 C fragrance 0.1

(Preparation method) A is heated to 80 ° C. to dissolve it.
After dispersion of B, the temperature is raised to 85 ° C. Add B to A and stir and mix. After cooling, C is added at 70 ° C.
After cooling to 30 ° C., an emulsion was obtained. Example 2 had an excellent moisturizing effect, and also had a sustained moisturizing effect and an excellent anti-stinging effect.

Example 3 Cream Ingredient% A PEG monostearate (40EO) 3.0 Sorbitan monopalmitate 1.0 Cetyl isooctanoate 10.0 Isopropyl myristate 5.0 Liquid paraffin (# 70) 5.0 Stearic acid 5.0 Cetanol 3.0 Paraffin wax 3.0 Lanolin 2.0 Methyl paraben 0.3 B Deep water off Kumejima Island, Okinawa Prefecture 20.0 Bentonite 0.5 Glycerin 5.0 Total amount with purified water 100.0 C Fragrance 0. 2

(Preparation method) A is heated to 80 ° C. to dissolve it.
After dispersion of B, the temperature is raised to 85 ° C. Add B to A and stir and mix. After cooling, C is added at 70 ° C.
Cooling to 30 ° C. gave a cream. Example 3 had an excellent moisturizing effect, and also had a sustained moisturizing effect and an excellent anti-stinging effect.

[0052]

(Preparation method) Component 7 is dissolved in Component 6. Component 3 is dispersed in Components 1 and 2, and Component 4 is added. Thereafter, the remaining components were added and mixed with stirring to obtain a gel. Example 4
Had excellent moisturizing effect, sustained moisturizing effect and anti-stinging effect.

 ──────────────────────────────────────────────────続 き Continued on the front page (72) Kunihiro Miyamoto 2-7 Tomicho, Nishi-ku, Nagoya-shi, Aichi Japan Inside of Menard Cosmetics Co., Ltd. (72) Inventor Jun Sato 2- Tomicho, Nishi-ku, Nagoya-shi, Aichi 7 Japan Menard Cosmetics Co., Ltd. (72) Inventor Satoru Satoru 2-7 Tomicho, Nishi-ku, Nagoya-shi, Aichi F-term (reference) 4C083 AA021 AA022 AB051 AB052 AB501 AB502 AC022 AC072 AC102 AC182 AC442 AC482 AD192 CC02 CC04 CC05 DD23 DD27 DD31 EE11 4C086 AA01 AA02 HA27 HA30 NA14 ZA89 ZA92 ZB11

Claims (3)

[Claims] 1. An external preparation for skin, characterized by containing deep water off Kumejima, Okinawa Prefecture. 2. An external preparation for skin comprising 5 to 80% of deep water off Kumejima, Okinawa Prefecture. 3. An anti-stinging agent comprising deep water off Kumejima, Okinawa Prefecture.