JP2001527079A5 - - Google Patents

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Publication number
JP2001527079A5
JP2001527079A5 JP2000526515A JP2000526515A JP2001527079A5 JP 2001527079 A5 JP2001527079 A5 JP 2001527079A5 JP 2000526515 A JP2000526515 A JP 2000526515A JP 2000526515 A JP2000526515 A JP 2000526515A JP 2001527079 A5 JP2001527079 A5 JP 2001527079A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000526515A
Other languages
Japanese (ja)
Other versions
JP2001527079A (ja
JP4405667B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/027644 external-priority patent/WO1999033836A1/en
Publication of JP2001527079A publication Critical patent/JP2001527079A/ja
Publication of JP2001527079A5 publication Critical patent/JP2001527079A5/ja
Application granted granted Critical
Publication of JP4405667B2 publication Critical patent/JP4405667B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2000526515A 1997-12-31 1998-12-30 K−252aの3’−エピマー誘導体 Expired - Fee Related JP4405667B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7026397P 1997-12-31 1997-12-31
US60/070,263 1997-12-31
PCT/US1998/027644 WO1999033836A1 (en) 1997-12-31 1998-12-30 3'-epimeric k-252a derivatives

Publications (3)

Publication Number Publication Date
JP2001527079A JP2001527079A (ja) 2001-12-25
JP2001527079A5 true JP2001527079A5 (enExample) 2005-12-22
JP4405667B2 JP4405667B2 (ja) 2010-01-27

Family

ID=22094212

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000526515A Expired - Fee Related JP4405667B2 (ja) 1997-12-31 1998-12-30 K−252aの3’−エピマー誘導体

Country Status (15)

Country Link
US (2) US6093713A (enExample)
EP (1) EP1044203B1 (enExample)
JP (1) JP4405667B2 (enExample)
KR (1) KR20010033737A (enExample)
CN (1) CN1285836A (enExample)
AT (1) ATE234308T1 (enExample)
AU (1) AU1947499A (enExample)
BR (1) BR9814543A (enExample)
CA (1) CA2315953C (enExample)
DE (1) DE69812177T2 (enExample)
DK (1) DK1044203T3 (enExample)
ES (1) ES2194385T3 (enExample)
NO (1) NO20003397L (enExample)
PT (1) PT1044203E (enExample)
WO (1) WO1999033836A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE301661T1 (de) 2000-12-08 2005-08-15 Ortho Mcneil Pharm Inc Makroheterocyclische verbindungen als kinase inhibitoren
DE60212836T2 (de) * 2001-05-16 2007-01-25 Gpc Biotech Ag Pyridylpyrimidin-derivate als wirksame verbindungen gegen prionen-krankheiten
US7018999B2 (en) 2001-05-16 2006-03-28 Cephalon, Inc. Methods for the treatment and prevention of pain
DE10161940A1 (de) 2001-12-17 2003-07-03 Nad Ag N-Carbacyclus-monosubstitutierte Indolocarbazole als Proteinkinase-inhibitoren
US6723844B1 (en) * 2003-02-27 2004-04-20 Abbott Laboratories Preparation of K-252a
DE102004025726B4 (de) * 2004-05-26 2006-07-06 Roder, Hanno, Dr. Verwendung eines spezifischen K252a-Derivats zur Verhinderung oder Behandlung der Alzheimerschen Krankheit
US20060058250A1 (en) * 2004-09-10 2006-03-16 Cephalon, Inc. Methods of treating proliferative skin diseases using carbazole derivatives
US20080021013A1 (en) * 2006-07-21 2008-01-24 Cephalon, Inc. JAK inhibitors for treatment of myeloproliferative disorders
AU2007334381B2 (en) * 2006-12-14 2014-02-13 Tautatis, Inc. Compositions and methods for the treatment of cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62155284A (ja) * 1985-12-27 1987-07-10 Kyowa Hakko Kogyo Co Ltd 生理活性物質k−252の誘導体
JPH0826036B2 (ja) 1987-01-22 1996-03-13 協和醗酵工業株式会社 生理活性物質k−252の誘導体
US4923986A (en) * 1987-03-09 1990-05-08 Kyowa Hakko Kogyo Co., Ltd. Derivatives of physiologically active substance K-252
US5461146A (en) * 1992-07-24 1995-10-24 Cephalon, Inc. Selected protein kinase inhibitors for the treatment of neurological disorders
US5621100A (en) * 1992-07-24 1997-04-15 Cephalon, Inc. K-252a derivatives for treatment of neurological disorders
WO1994027982A1 (en) 1993-05-28 1994-12-08 Cephalon, Inc. Use of indolocarbazole derivatives to treat a pathological condition of the prostate
US5468872A (en) * 1993-09-16 1995-11-21 Cephalon, Inc. K-252a functional derivatives potentiate neurotrophin-3 for the treatment of neurological disorders
CA2170888A1 (en) * 1994-07-04 1996-01-18 Masahiko Kinugawa Process for producing indolocarbazole derivative
AU6657596A (en) 1995-07-31 1997-02-26 Ciba-Geigy Ag Trindene compounds
WO1997007081A2 (en) 1995-08-11 1997-02-27 Yale University Glycosylated indolocarbazole synthesis

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