JP2001523959A5 - - Google Patents

Download PDF

Info

Publication number
JP2001523959A5
JP2001523959A5 JP1998546254A JP54625498A JP2001523959A5 JP 2001523959 A5 JP2001523959 A5 JP 2001523959A5 JP 1998546254 A JP1998546254 A JP 1998546254A JP 54625498 A JP54625498 A JP 54625498A JP 2001523959 A5 JP2001523959 A5 JP 2001523959A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998546254A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001523959A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/007968 external-priority patent/WO1998048009A2/en
Publication of JP2001523959A publication Critical patent/JP2001523959A/ja
Publication of JP2001523959A5 publication Critical patent/JP2001523959A5/ja
Ceased legal-status Critical Current

Links

JP54625498A 1997-04-21 1998-04-21 疾患のリボザイム処置のための物質および方法 Ceased JP2001523959A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4449297P 1997-04-21 1997-04-21
US60/044,492 1997-04-21
US4614797P 1997-05-09 1997-05-09
US60/046,147 1997-05-09
PCT/US1998/007968 WO1998048009A2 (en) 1997-04-21 1998-04-21 Materials and methods for ribozyme treatment of retinal diseases

Publications (2)

Publication Number Publication Date
JP2001523959A JP2001523959A (ja) 2001-11-27
JP2001523959A5 true JP2001523959A5 (OSRAM) 2005-12-02

Family

ID=26721633

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54625498A Ceased JP2001523959A (ja) 1997-04-21 1998-04-21 疾患のリボザイム処置のための物質および方法

Country Status (8)

Country Link
US (1) US6225291B1 (OSRAM)
EP (1) EP0977841A2 (OSRAM)
JP (1) JP2001523959A (OSRAM)
AU (1) AU735788B2 (OSRAM)
BR (1) BR9808606A (OSRAM)
CA (1) CA2287508A1 (OSRAM)
NZ (1) NZ500427A (OSRAM)
WO (1) WO1998048009A2 (OSRAM)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9808606A (pt) 1997-04-21 2000-05-23 Univ Florida Materiais e métodos para tratamento de doenças com ribozimas
DE19956568A1 (de) * 1999-01-30 2000-08-17 Roland Kreutzer Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
US6485976B1 (en) 1999-04-30 2002-11-26 City Of Hope Use of adeno-associated virus (AAV) to deliver genes
WO2000066780A2 (en) * 1999-04-30 2000-11-09 University Of Florida Adeno-associated virus-delivered ribozyme compositions and methods of use
US7829693B2 (en) * 1999-11-24 2010-11-09 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of a target gene
US8546143B2 (en) 2001-01-09 2013-10-01 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of a target gene
US20030003582A1 (en) * 2001-05-08 2003-01-02 Tranzyme, Inc. Trans-viral vector mediated gene transfer to the retina
JP5578388B2 (ja) 2002-04-18 2014-08-27 オプコ ファーマシューティカルズ、エルエルシー 中枢神経システム及び/若しくは眼の細胞及び組織中の遺伝子の特異的阻害のための手段と方法
US7148342B2 (en) 2002-07-24 2006-12-12 The Trustees Of The University Of Pennyslvania Compositions and methods for sirna inhibition of angiogenesis
ATE443764T1 (de) 2002-11-04 2009-10-15 Univ Massachusetts Allelspezifische rna-interferenz
US8680063B2 (en) 2003-09-12 2014-03-25 University Of Massachusetts RNA interference for the treatment of gain-of-function disorders
JP2009504782A (ja) 2005-08-18 2009-02-05 アルナイラム ファーマシューティカルズ インコーポレイテッド 神経疾患を治療するための方法および組成物
CA2683469C (en) 2007-04-12 2019-11-26 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Genetic suppression and replacement
US8470792B2 (en) 2008-12-04 2013-06-25 Opko Pharmaceuticals, Llc. Compositions and methods for selective inhibition of VEGF
US8450473B2 (en) 2009-04-30 2013-05-28 The Research Foundation Of State University Of New York Compositions and methods for therapy of macular degeneration
KR20200047642A (ko) 2010-04-23 2020-05-07 유니버시티 오브 플로리다 리서치 파운데이션, 인크. 레베르 선천성 흑내장-1(lca1)의 치료를 위한 재조합 아데노-관련된 바이러스-구아닐레이트 사이클라제 조성물 및 방법
EP3137497B2 (en) 2014-05-02 2025-03-05 Genzyme Corporation Aav vectors for retinal and cns gene therapy
WO2016044478A1 (en) 2014-09-16 2016-03-24 Genzyme Corporation Adeno-associated viral vectors for treating myocilin (myoc) glaucoma
EP4012035B1 (en) 2014-09-16 2024-11-06 Genzyme Corporation Adeno-associated viral vectors for treating myocilin (myoc) glaucoma
US10426789B2 (en) 2015-02-26 2019-10-01 Ionis Pharmaceuticals, Inc. Allele specific modulators of P23H rhodopsin
US11653636B2 (en) * 2019-11-15 2023-05-23 University Of Ulsan Foundation For Industry Cooperation Method of making a rat model of retinal degeneration and rat model made thereby
JP2023513004A (ja) 2020-01-29 2023-03-30 ジェンザイム・コーポレーション 眼科遺伝子療法のための改変されたアデノ随伴ウイルスカプシドタンパク質およびその使用方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5037746A (en) 1986-12-03 1991-08-06 University Patents, Inc. RNA ribozyme polymerases, and methods
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US5116742A (en) 1986-12-03 1992-05-26 University Patents, Inc. RNA ribozyme restriction endoribonucleases and methods
US5646020A (en) 1992-05-14 1997-07-08 Ribozyme Pharmaceuticals, Inc. Hammerhead ribozymes for preferred targets
US5498539A (en) * 1992-07-02 1996-03-12 Daiichi Pharmaceutical Co., Ltd. Bovine endothelial nitric oxide synthase nucleic acids
US5639655A (en) 1993-01-19 1997-06-17 Ribozyme Pharmaceuticals, Inc. PML-RARA targeted ribozymes
US6410322B1 (en) * 1993-07-27 2002-06-25 Hybridon Inc Antisense oligonucleotide inhibition of vascular endothelial growth factor expression
US5646031A (en) 1995-05-16 1997-07-08 Northern Illinois University SArMV and sCYMVI hairpin ribozymes
GB9519299D0 (en) * 1995-09-21 1995-11-22 Farrar Gwyneth J Genetic strategy
GB9604449D0 (en) 1996-03-01 1996-05-01 Farrar Gwyneth J Genetic strategy ii
BR9809284A (pt) 1997-04-21 2004-08-03 Univ Florida Construto e processo para expressão de polinucleotìdeo em altos nìveis
BR9808606A (pt) 1997-04-21 2000-05-23 Univ Florida Materiais e métodos para tratamento de doenças com ribozimas

Similar Documents

Publication Publication Date Title
JP2000509635A5 (OSRAM)
JP2000507042A5 (OSRAM)
JP2000509912A5 (OSRAM)
JP2000509637A5 (OSRAM)
JP2000509942A5 (OSRAM)
JP2001524836A5 (OSRAM)
JP2001523240A5 (OSRAM)
JP2000509587A5 (OSRAM)
JP2000507369A5 (OSRAM)
JP2000507433A5 (OSRAM)
JP2000508866A5 (OSRAM)
JP2000510793A5 (OSRAM)
JP2001508794A5 (OSRAM)
JP2000508841A5 (OSRAM)
JP2001514522A5 (OSRAM)
JP2000508680A5 (OSRAM)
JP2000509853A5 (OSRAM)
JP2000509755A5 (OSRAM)
JP2001524146A5 (OSRAM)
JP2000510969A5 (OSRAM)
JP2000510247A5 (OSRAM)
JP2000508102A5 (OSRAM)
JP2000508836A5 (OSRAM)
JP2000509520A5 (OSRAM)
JP2000509818A5 (OSRAM)