JP2001523959A5 - - Google Patents
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- Publication number
- JP2001523959A5 JP2001523959A5 JP1998546254A JP54625498A JP2001523959A5 JP 2001523959 A5 JP2001523959 A5 JP 2001523959A5 JP 1998546254 A JP1998546254 A JP 1998546254A JP 54625498 A JP54625498 A JP 54625498A JP 2001523959 A5 JP2001523959 A5 JP 2001523959A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Description
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4449297P | 1997-04-21 | 1997-04-21 | |
US60/044,492 | 1997-04-21 | ||
US4614797P | 1997-05-09 | 1997-05-09 | |
US60/046,147 | 1997-05-09 | ||
PCT/US1998/007968 WO1998048009A2 (en) | 1997-04-21 | 1998-04-21 | Materials and methods for ribozyme treatment of retinal diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2001523959A JP2001523959A (ja) | 2001-11-27 |
JP2001523959A5 true JP2001523959A5 (ja) | 2005-12-02 |
Family
ID=26721633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP54625498A Ceased JP2001523959A (ja) | 1997-04-21 | 1998-04-21 | 疾患のリボザイム処置のための物質および方法 |
Country Status (8)
Country | Link |
---|---|
US (1) | US6225291B1 (ja) |
EP (1) | EP0977841A2 (ja) |
JP (1) | JP2001523959A (ja) |
AU (1) | AU735788B2 (ja) |
BR (1) | BR9808606A (ja) |
CA (1) | CA2287508A1 (ja) |
NZ (1) | NZ500427A (ja) |
WO (1) | WO1998048009A2 (ja) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0977841A2 (en) | 1997-04-21 | 2000-02-09 | University Of Florida | Materials and methods for ribozyme treatment of retinal diseases |
DE19956568A1 (de) * | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
JP2002542805A (ja) | 1999-04-30 | 2002-12-17 | ユニバーシティ オブ フロリダ | アデノ随伴ウイルス送達リボザイム組成物および使用方法 |
WO2000066720A2 (en) * | 1999-04-30 | 2000-11-09 | City Of Hope | The use of adeno-associated virus (aav) deliver cytoprotective genes |
US7829693B2 (en) * | 1999-11-24 | 2010-11-09 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of a target gene |
US8546143B2 (en) | 2001-01-09 | 2013-10-01 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of a target gene |
US20030003582A1 (en) * | 2001-05-08 | 2003-01-02 | Tranzyme, Inc. | Trans-viral vector mediated gene transfer to the retina |
EP1495120B1 (en) | 2002-04-18 | 2012-10-10 | Acuity Pharmaceuticals, Inc | Means and methods for the specific modulation of target genes in the eye |
US7148342B2 (en) | 2002-07-24 | 2006-12-12 | The Trustees Of The University Of Pennyslvania | Compositions and methods for sirna inhibition of angiogenesis |
WO2004042027A2 (en) | 2002-11-04 | 2004-05-21 | University Of Massachusetts | Allele-specific rna interference |
US8680063B2 (en) | 2003-09-12 | 2014-03-25 | University Of Massachusetts | RNA interference for the treatment of gain-of-function disorders |
EP1937066A4 (en) | 2005-08-18 | 2008-12-24 | Alnylam Pharmaceuticals Inc | METHOD AND COMPOSITIONS FOR THE TREATMENT OF NERVOUS DISEASES |
CA2683469C (en) | 2007-04-12 | 2019-11-26 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth | Genetic suppression and replacement |
SG171952A1 (en) | 2008-12-04 | 2011-07-28 | Opko Ophthalmics Llc | Compositions and methods for selective inhibition of pro-angiogenic vegf isoforms |
WO2010127209A2 (en) * | 2009-04-30 | 2010-11-04 | The Research Foundation Of State University Of New York | Compositions and methods for therapy of macular degeneration |
RS58434B1 (sr) | 2010-04-23 | 2019-04-30 | Univ Florida | Sastavi raav-guanilatne ciklaze i postupci tretiranja leberove urođene amauroze-1 (lca1) |
DK3137497T3 (da) | 2014-05-02 | 2021-07-12 | Genzyme Corp | Aav-vektorer til retinal- og cns-genterapi |
CA2961523A1 (en) | 2014-09-16 | 2016-03-24 | Genzyme Corporation | Adeno-associated viral vectors for treating myocilin (myoc) glaucoma |
EP4012035A1 (en) | 2014-09-16 | 2022-06-15 | Genzyme Corporation | Adeno-associated viral vectors for treating myocilin (myoc) glaucoma |
BR112017017178A2 (pt) | 2015-02-26 | 2018-04-03 | Ionis Pharmaceuticals Inc | moduladores específicos de alelo de rodopsina de p23h |
US11653636B2 (en) * | 2019-11-15 | 2023-05-23 | University Of Ulsan Foundation For Industry Cooperation | Method of making a rat model of retinal degeneration and rat model made thereby |
CN115989234A (zh) | 2020-01-29 | 2023-04-18 | 建新公司 | 用于眼部基因疗法的经修饰的腺相关病毒衣壳蛋白及其使用方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5116742A (en) | 1986-12-03 | 1992-05-26 | University Patents, Inc. | RNA ribozyme restriction endoribonucleases and methods |
US5037746A (en) | 1986-12-03 | 1991-08-06 | University Patents, Inc. | RNA ribozyme polymerases, and methods |
US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
US5646020A (en) | 1992-05-14 | 1997-07-08 | Ribozyme Pharmaceuticals, Inc. | Hammerhead ribozymes for preferred targets |
US5498539A (en) * | 1992-07-02 | 1996-03-12 | Daiichi Pharmaceutical Co., Ltd. | Bovine endothelial nitric oxide synthase nucleic acids |
US5639655A (en) | 1993-01-19 | 1997-06-17 | Ribozyme Pharmaceuticals, Inc. | PML-RARA targeted ribozymes |
US6410322B1 (en) | 1993-07-27 | 2002-06-25 | Hybridon Inc | Antisense oligonucleotide inhibition of vascular endothelial growth factor expression |
US5646031A (en) | 1995-05-16 | 1997-07-08 | Northern Illinois University | SArMV and sCYMVI hairpin ribozymes |
GB9519299D0 (en) | 1995-09-21 | 1995-11-22 | Farrar Gwyneth J | Genetic strategy |
GB9604449D0 (en) | 1996-03-01 | 1996-05-01 | Farrar Gwyneth J | Genetic strategy ii |
WO1998048027A2 (en) * | 1997-04-21 | 1998-10-29 | University Of Florida | Materials and methods for treatment of retinal diseases |
EP0977841A2 (en) | 1997-04-21 | 2000-02-09 | University Of Florida | Materials and methods for ribozyme treatment of retinal diseases |
-
1998
- 1998-04-21 EP EP98918493A patent/EP0977841A2/en not_active Withdrawn
- 1998-04-21 WO PCT/US1998/007968 patent/WO1998048009A2/en not_active Application Discontinuation
- 1998-04-21 NZ NZ500427A patent/NZ500427A/xx unknown
- 1998-04-21 JP JP54625498A patent/JP2001523959A/ja not_active Ceased
- 1998-04-21 BR BR9808606-5A patent/BR9808606A/pt not_active IP Right Cessation
- 1998-04-21 AU AU71406/98A patent/AU735788B2/en not_active Ceased
- 1998-04-21 US US09/063,667 patent/US6225291B1/en not_active Expired - Lifetime
- 1998-04-21 CA CA002287508A patent/CA2287508A1/en not_active Abandoned