JP2001523255A - 抗血栓剤 - Google Patents

抗血栓剤

Info

Publication number
JP2001523255A
JP2001523255A JP54737098A JP54737098A JP2001523255A JP 2001523255 A JP2001523255 A JP 2001523255A JP 54737098 A JP54737098 A JP 54737098A JP 54737098 A JP54737098 A JP 54737098A JP 2001523255 A JP2001523255 A JP 2001523255A
Authority
JP
Japan
Prior art keywords
formula
compound
methoxy
compounds
mmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP54737098A
Other languages
English (en)
Japanese (ja)
Inventor
チルガゼ，ニコライ・ユーリ
ハーパー，リチャード・ワルツ
コーン，トッド・ジョナサン
リン，ホ−シェン
マッコワン，ジェファーソン・アール
パルコウィッツ，アラン・デイビッド
サル，ダニエル・ジョン
スミス，ジェラルド・フロイド
タケウチ，クミコ
ワイリー，マイケル・ロバート
ジャン，ミンシェン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JP2001523255A publication Critical patent/JP2001523255A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP54737098A 1997-04-30 1998-04-30 抗血栓剤 Pending JP2001523255A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4517397P 1997-04-30 1997-04-30
US60/045,173 1997-04-30
PCT/US1998/008700 WO1998048798A1 (fr) 1997-04-30 1998-04-30 Agents antithrombotiques

Publications (1)

Publication Number Publication Date
JP2001523255A true JP2001523255A (ja) 2001-11-20

Family

ID=21936403

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54737098A Pending JP2001523255A (ja) 1997-04-30 1998-04-30 抗血栓剤

Country Status (5)

Country Link
EP (1) EP0993300A4 (fr)
JP (1) JP2001523255A (fr)
AU (1) AU7563598A (fr)
CA (1) CA2287901A1 (fr)
WO (1) WO1998048798A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2731184C (fr) 2008-08-22 2017-03-21 Baxter International Inc. Derives de carbonate de benzyle polymeriques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
ZA928276B (en) * 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.

Also Published As

Publication number Publication date
CA2287901A1 (fr) 1998-11-05
EP0993300A4 (fr) 2002-07-31
AU7563598A (en) 1998-11-24
EP0993300A1 (fr) 2000-04-19
WO1998048798A1 (fr) 1998-11-05

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