JP2001521504A5 - - Google Patents

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Publication number
JP2001521504A5
JP2001521504A5 JP1998541945A JP54194598A JP2001521504A5 JP 2001521504 A5 JP2001521504 A5 JP 2001521504A5 JP 1998541945 A JP1998541945 A JP 1998541945A JP 54194598 A JP54194598 A JP 54194598A JP 2001521504 A5 JP2001521504 A5 JP 2001521504A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998541945A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001521504A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/006365 external-priority patent/WO1998043963A1/en
Publication of JP2001521504A publication Critical patent/JP2001521504A/ja
Publication of JP2001521504A5 publication Critical patent/JP2001521504A5/ja
Ceased legal-status Critical Current

Links

JP54194598A 1997-04-01 1998-03-31 メタロプロテイナーゼ阻害薬、それらを含有する薬剤組成物および薬剤としてのそれらの使用 Ceased JP2001521504A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82531897A 1997-04-01 1997-04-01
US08/825,318 1997-04-01
PCT/US1998/006365 WO1998043963A1 (en) 1997-04-01 1998-03-31 Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses

Publications (2)

Publication Number Publication Date
JP2001521504A JP2001521504A (ja) 2001-11-06
JP2001521504A5 true JP2001521504A5 (enExample) 2005-11-24

Family

ID=25243697

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54194598A Ceased JP2001521504A (ja) 1997-04-01 1998-03-31 メタロプロテイナーゼ阻害薬、それらを含有する薬剤組成物および薬剤としてのそれらの使用

Country Status (8)

Country Link
EP (1) EP0973748A1 (enExample)
JP (1) JP2001521504A (enExample)
KR (1) KR20010005940A (enExample)
AU (1) AU747280B2 (enExample)
BR (1) BR9809062A (enExample)
CA (1) CA2285372A1 (enExample)
NZ (1) NZ338082A (enExample)
WO (1) WO1998043963A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69836877D1 (de) 1997-07-22 2007-02-22 Shionogi & Co Verwendung von Matrix- Metalloproteinase Inhibitoren zur Behandlung oder Vorbeugung von Glomerulopathie
BR9810841A (pt) 1997-07-31 2001-07-10 Procter & Gamble Inibidores de metaloprotease alicìclicos
IL127496A0 (en) * 1997-12-19 1999-10-28 Pfizer Prod Inc The use of MMP inhibitors for the treatment of ocular angiogenesis
EP1918278A1 (en) 1998-02-04 2008-05-07 Novartis AG Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases
US6410580B1 (en) 1998-02-04 2002-06-25 Novartis Ag Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases
US6075136A (en) * 1998-02-17 2000-06-13 Incyte Pharmaceuticals, Inc. Prostate-associated serine protease
US6492394B1 (en) 1998-12-22 2002-12-10 Syntex (U.S.A.) Llc Sulfonamide hydroxamates
US6225311B1 (en) 1999-01-27 2001-05-01 American Cyanamid Company Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors
BR0007784A (pt) 1999-01-27 2002-02-05 American Cyanamid Co Composto, método para inibir mudanças patológicas mediadas pela enzima que converte o tnf-alfa (tace) em um mamìfero, composição farmacêutica, e, processo para preparar um composto
US6313123B1 (en) 1999-01-27 2001-11-06 American Cyanamid Company Acetylenic sulfonamide thiol tace inhibitors
US6326516B1 (en) 1999-01-27 2001-12-04 American Cyanamid Company Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors
US6762178B2 (en) 1999-01-27 2004-07-13 Wyeth Holdings Corporation Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6946473B2 (en) 1999-01-27 2005-09-20 Wyeth Holdings Corporation Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors
US6277885B1 (en) 1999-01-27 2001-08-21 American Cyanamid Company Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6753337B2 (en) 1999-01-27 2004-06-22 Wyeth Holdings Corporation Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
US6340691B1 (en) 1999-01-27 2002-01-22 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors
US6200996B1 (en) 1999-01-27 2001-03-13 American Cyanamid Company Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors
MXPA01008855A (es) 1999-03-03 2002-07-02 Procter & Gamble Inhibidores de metaloproteasa que contienen alquenilo y alquinilo.
HK1044935A1 (zh) 1999-03-03 2002-11-08 The Procter & Gamble Company 双异取代的金属蛋白酶抑制剂
US6696456B1 (en) * 1999-10-14 2004-02-24 The Procter & Gamble Company Beta disubstituted metalloprotease inhibitors
CN1610661A (zh) 2001-11-01 2005-04-27 惠氏控股公司 用作基质金属蛋白酶和tace的抑制剂的丙二烯芳基磺酰胺异羟肟酸
PE20030701A1 (es) 2001-12-20 2003-08-21 Schering Corp Compuestos para el tratamiento de trastornos inflamatorios
CA2471814C (en) 2001-12-27 2011-03-15 Sumitomo Pharmaceuticals Co., Ltd. Hydroxamic acid derivative and mmp inhibitor containing the same as active ingredient
EP2428509A1 (en) 2002-06-12 2012-03-14 Symphony Evolution, Inc. Human adam-10 inhibitors
WO2005021489A2 (en) 2002-12-23 2005-03-10 Wyeth Holdings Corporation Acetylenic aryl sulfonate hydroxamic acid tace and matrix metalloproteinase inhibitors
US20090018094A1 (en) * 2006-12-01 2009-01-15 Loma Linda University Medical Center Inhibition of brain enzymes involved in cerebral amyloid angiopathy and macular degeneration
WO2020070239A1 (en) 2018-10-04 2020-04-09 INSERM (Institut National de la Santé et de la Recherche Médicale) Egfr inhibitors for treating keratodermas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT766664E (pt) * 1994-06-22 2000-08-31 British Biotech Pharm Inibidores de metaloproteinases
US5863949A (en) * 1995-03-08 1999-01-26 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
DK0757984T3 (da) * 1995-08-08 2003-03-03 Ono Pharmaceutical Co Hydroxamsyrederivater, der kan anvendes til inhibering af gelatinase
PT874830E (pt) * 1995-12-08 2003-06-30 Agouron Pharma Inibidor de metaloproteinases composicao farmaceutica contendo este inibidor e a utilizacao farmaceutica e metodo util para a sua preparacao
CN100413859C (zh) * 1996-01-23 2008-08-27 盐野义制药株式会社 磺化的氨基酸衍生物及含有它的金属蛋白酶抑制剂

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