|
EP0813065A3
(en)
*
|
1996-06-13 |
1998-07-22 |
F. Hoffmann-La Roche Ag |
Modulation of LC132 (opioid-like) receptor function
|
|
CA2206192A1
(en)
|
1996-06-13 |
1997-12-13 |
F. Hoffmann-La Roche Ag |
Modulation of lc132 (opioid-like) receptor function
|
|
WO1999003880A1
(en)
*
|
1997-07-15 |
1999-01-28 |
Novo Nordisk A/S |
Nociceptin analogues
|
|
WO1999003491A1
(en)
*
|
1997-07-15 |
1999-01-28 |
Novo Nordisk A/S |
New use of nociceptin
|
|
US5929035A
(en)
*
|
1998-04-14 |
1999-07-27 |
Regents Of The University Of Michigan |
Methods of treating intestinal disorders
|
|
GB9815618D0
(en)
*
|
1998-07-18 |
1998-09-16 |
Univ Manchester |
Treatment of dyskinesia
|
|
MA26659A1
(fr)
|
1998-08-06 |
2004-12-20 |
Pfizer |
Dérivés de benzimidazole nouveaux, compositions pharmaceutiques les contenant et procédé pour leur préparation.
|
|
US6582457B2
(en)
*
|
2001-02-15 |
2003-06-24 |
Radiant Medical, Inc. |
Method of controlling body temperature while reducing shivering
|
|
US6849449B2
(en)
*
|
2001-03-01 |
2005-02-01 |
Regents Of The University Of Michigan |
Orphanin FQ receptor nucleic acids
|
|
EP1406629A1
(en)
*
|
2001-07-02 |
2004-04-14 |
Omeros Corporation |
Method for inducing analgesia comprising administration alternatively of an opioid receptor agonist and an opioid receptor like receptor 1 agonist for and an implantable infusion pump
|
|
US20030040479A1
(en)
*
|
2001-07-02 |
2003-02-27 |
Omeros Corporation |
Rotational intrathecal analgesia method and device
|
|
US7049287B2
(en)
*
|
2001-10-09 |
2006-05-23 |
Synvax, Inc. |
Nociceptin-based analgesics
|
|
EP1499888B1
(en)
*
|
2002-04-29 |
2010-07-07 |
Euro-Celtique S.A. |
Conformationally constrained peptides that bind the orl-1 receptor
|
|
WO2004013292A2
(en)
*
|
2002-08-02 |
2004-02-12 |
Incyte Corporation |
Extracellular messengers
|
|
NZ538307A
(en)
|
2002-09-09 |
2008-04-30 |
Janssen Pharmaceutica Nv |
Hydroxy alkyl substituted 1,3,8-triazaspiro[4.5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
|
|
HRP20150037T4
(hr)
|
2003-04-08 |
2022-09-02 |
Progenics Pharmaceuticals, Inc. |
Farmaceutske formulacije koje sadrže metilnaltrekson
|
|
US7173010B2
(en)
*
|
2003-05-19 |
2007-02-06 |
Regents Of The University Of Michigan |
Orphanin FQ receptor
|
|
US9662325B2
(en)
|
2005-03-07 |
2017-05-30 |
The University Of Chicago |
Use of opioid antagonists to attenuate endothelial cell proliferation and migration
|
|
ES2714198T3
(es)
|
2005-03-07 |
2019-05-27 |
Univ Chicago |
Uso de antagonistas opioideos para atenuar la proliferación y la migración de células endoteliales
|
|
US8524731B2
(en)
|
2005-03-07 |
2013-09-03 |
The University Of Chicago |
Use of opioid antagonists to attenuate endothelial cell proliferation and migration
|
|
US8518962B2
(en)
|
2005-03-07 |
2013-08-27 |
The University Of Chicago |
Use of opioid antagonists
|
|
AR057035A1
(es)
|
2005-05-25 |
2007-11-14 |
Progenics Pharm Inc |
SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
|
|
AR057325A1
(es)
|
2005-05-25 |
2007-11-28 |
Progenics Pharm Inc |
Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
|
|
US7655670B2
(en)
|
2005-06-02 |
2010-02-02 |
Janssen Pharmaceutica N.V. |
3-spirocyclic indolyl derivatives useful as ORL-1 receptor modulators
|
|
TWI489984B
(zh)
|
2006-08-04 |
2015-07-01 |
Wyeth Corp |
用於非經腸道傳輸化合物之配方及其用途
|
|
CN103202840B
(zh)
|
2006-11-28 |
2015-02-11 |
詹森药业有限公司 |
3-(3-氨基-2-(r)-羟基-丙基)-1-(4-氟-苯基)-8-(8-甲基-萘-1-基甲基)-1,3,8-三氮杂-螺[4.5]癸烷-4-酮的盐
|
|
MX2009010550A
(es)
|
2007-03-29 |
2009-12-14 |
Progenics Pharm Inc |
Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas.
|
|
SI2565195T1
(sl)
|
2007-03-29 |
2015-09-30 |
Wyeth Llc |
Periferalni opioidni receptorji in antagonisti in njih uporaba
|
|
CL2008000905A1
(es)
|
2007-03-29 |
2008-08-22 |
Progenics Pharm Inc |
Compuestos derivados de morfina, antagonistas del receptor opioide periferico; metodo de preparacion; composicion farmaceutica; y uso para reducir los efectos de la actividad opioide endogena.
|
|
JP5490677B2
(ja)
|
2007-04-09 |
2014-05-14 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
不安及び鬱病の処置のためのｏｒｌ−１受容体リガンドとしての１，３，８−三置換−１，３，８−トリアザ−スピロ［４．５］デカン−４−オン誘導体
|
|
JP2010527980A
(ja)
|
2007-05-22 |
2010-08-19 |
プロシディオン・リミテッド |
代謝障害を治療するための二環状アリールおよびヘテロアリール化合物
|
|
WO2009030962A1
(en)
|
2007-09-07 |
2009-03-12 |
Prosidion Limited |
Bicyclic aryl and heteroaryl receptor modulators
|
|
EP2240489A1
(en)
|
2008-02-06 |
2010-10-20 |
Progenics Pharmaceuticals, Inc. |
Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
|
|
EP2278966B1
(en)
|
2008-03-21 |
2019-10-09 |
The University of Chicago |
Treatment with opioid antagonists and mtor inhibitors
|
|
CA2676881C
(en)
|
2008-09-30 |
2017-04-25 |
Wyeth |
Peripheral opioid receptor antagonists and uses thereof
|
|
RU2492482C1
(ru)
*
|
2012-10-08 |
2013-09-10 |
Игорь Петрович Папышев |
Способ диагностики причины смерти от интоксикации наркотическими веществами группы опиатов
|