JP2001518523A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2001518523A5 JP2001518523A5 JP2000514677A JP2000514677A JP2001518523A5 JP 2001518523 A5 JP2001518523 A5 JP 2001518523A5 JP 2000514677 A JP2000514677 A JP 2000514677A JP 2000514677 A JP2000514677 A JP 2000514677A JP 2001518523 A5 JP2001518523 A5 JP 2001518523A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- contrast agent
- state
- composition
- compositions described
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94298997A | 1997-10-02 | 1997-10-02 | |
| US08/942,989 | 1997-10-02 | ||
| PCT/US1998/020182 WO1999017809A2 (en) | 1997-10-02 | 1998-09-24 | Contrast-enhanced diagnostic imaging method for monitoring interventional therapies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005276942A Division JP2006077020A (ja) | 1997-10-02 | 2005-09-22 | インターベンショナル療法をモニタリングするためのコントラスト増強型診断的画像化方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001518523A JP2001518523A (ja) | 2001-10-16 |
| JP2001518523A5 true JP2001518523A5 (enExample) | 2006-01-05 |
Family
ID=25478927
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000514677A Pending JP2001518523A (ja) | 1997-10-02 | 1998-09-24 | インターベンショナル療法をモニタリングするためのコントラスト増強型診断的画像化方法 |
| JP2005276942A Pending JP2006077020A (ja) | 1997-10-02 | 2005-09-22 | インターベンショナル療法をモニタリングするためのコントラスト増強型診断的画像化方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005276942A Pending JP2006077020A (ja) | 1997-10-02 | 2005-09-22 | インターベンショナル療法をモニタリングするためのコントラスト増強型診断的画像化方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6861045B1 (enExample) |
| EP (1) | EP1019094B1 (enExample) |
| JP (2) | JP2001518523A (enExample) |
| KR (1) | KR20010030854A (enExample) |
| AT (1) | ATE254479T1 (enExample) |
| AU (1) | AU742438C (enExample) |
| BR (1) | BR9812716A (enExample) |
| CA (1) | CA2303426C (enExample) |
| DE (1) | DE69819925T2 (enExample) |
| DK (1) | DK1019094T3 (enExample) |
| ES (1) | ES2206996T3 (enExample) |
| HU (1) | HUP0101245A3 (enExample) |
| IL (1) | IL134985A0 (enExample) |
| IS (1) | IS2041B (enExample) |
| NO (1) | NO321966B1 (enExample) |
| NZ (1) | NZ503402A (enExample) |
| PT (1) | PT1019094E (enExample) |
| SK (1) | SK4842000A3 (enExample) |
| WO (1) | WO1999017809A2 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6495118B1 (en) | 1997-09-26 | 2002-12-17 | Schering Aktiengesellschaft | Lipophilic metal complexes for necrosis and infarction imaging |
| DE69819925T2 (de) * | 1997-10-02 | 2004-09-02 | Epix Medical, Inc., Cambridge | Kontrastverstärktes Diagnosebildererzeugungsverfahren zur Überwachung von therapeutischen Eingriffen |
| US6167297A (en) * | 1999-05-05 | 2000-12-26 | Benaron; David A. | Detecting, localizing, and targeting internal sites in vivo using optical contrast agents |
| EP1237593A1 (en) | 1999-11-22 | 2002-09-11 | Epix Medical, Inc. | Imaging sexual response |
| AU2001231090A1 (en) * | 2000-01-22 | 2001-07-31 | Epix Medical, Inc. | Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage |
| TWI221406B (en) | 2001-07-30 | 2004-10-01 | Epix Medical Inc | Systems and methods for targeted magnetic resonance imaging of the vascular system |
| JP2004537580A (ja) * | 2001-08-10 | 2004-12-16 | エピックス メディカル, インコーポレイテッド | 延長された循環半減期を有するポリペプチド結合体 |
| US7794693B2 (en) | 2002-03-01 | 2010-09-14 | Bracco International B.V. | Targeting vector-phospholipid conjugates |
| US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
| US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
| AU2003278807A1 (en) | 2002-03-01 | 2004-08-13 | Bracco International B.V. | Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy |
| EP2014310B8 (en) | 2002-03-01 | 2012-12-26 | Dyax Corp. | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
| EP1603935A4 (en) | 2003-03-03 | 2007-03-21 | Dyax Corp | SPECIFIC TO HGF RECEPTOR (cMET) BINDING PEPTIDES AND THEIR USE |
| US20050064045A1 (en) * | 2003-09-18 | 2005-03-24 | Sheng-Ping Zhong | Injectable therapeutic formulations |
| EP1747026A1 (en) * | 2004-05-18 | 2007-01-31 | Siemens Aktiengesellschaft | Biomolecular contrast agents for therapy control in radiation therapy with proton or ion beams |
| US7585492B2 (en) | 2004-05-18 | 2009-09-08 | Siemens Aktiengesellschaft | Biomolecular contrast agents for therapy success and dose monitoring in radiation therapy with proton or ion beams |
| JP2006248978A (ja) * | 2005-03-10 | 2006-09-21 | Mebiopharm Co Ltd | 新規なリポソーム製剤 |
| WO2007063454A1 (en) * | 2005-11-29 | 2007-06-07 | Koninklijke Philips Electronics N.V. | Distinguishing bound and unbound contrast agents using magnetic resonance |
| WO2007073792A1 (de) * | 2005-12-19 | 2007-07-05 | Bayer Schering Pharma Aktiengesellschaft | Verfahren zur herstellung von 4,4-diphenylcyclohexanol |
| US20080044358A1 (en) * | 2006-08-17 | 2008-02-21 | Vincent Jacques | Methods for lymph system imaging |
| DE102006049821A1 (de) | 2006-10-18 | 2008-04-24 | Bayer Schering Pharma Aktiengesellschaft | Metallchelate mit perfluoriertem PEG-Rest, Verfahren zu deren Herstellung, sowie deren Verwendung |
| US20100092389A1 (en) * | 2008-10-10 | 2010-04-15 | The General Hospital Corporation | Detection of atherosclerosis using indocyanine green |
| US9423480B2 (en) * | 2008-10-27 | 2016-08-23 | The University Of Western Ontario | System and method for magnetic resonance imaging |
| KR20110139274A (ko) | 2009-03-19 | 2011-12-28 | 와이어쓰 엘엘씨 | [2-(8,9-다이옥소-2,6-다이아자바이사이클로[5.2.0]논-1(7)-엔-2-일)에틸]포스폰산 및 이의 전구체의 제조 방법 |
| WO2010121133A2 (en) | 2009-04-17 | 2010-10-21 | The General Hospital Corporation | Multimodal imaging of fibrin |
| RU2559930C2 (ru) | 2010-02-02 | 2015-08-20 | Конинклейке Филипс Электроникс Н.В. | Формирование функциональных изображений |
| AU2012282678B2 (en) | 2011-07-11 | 2016-03-03 | California Institute Of Technology | Akt-specific capture agents, compositions, and methods of using and making |
| TW201514188A (zh) * | 2013-03-13 | 2015-04-16 | Lantheus Medical Imaging Inc | 製備釓磷維塞三鈉單水合物之方法 |
| WO2014165990A1 (en) | 2013-04-08 | 2014-10-16 | Sunnybrook Research Institute | System and method for imaging biomarkers indicative of cardiac thermal ablation lesions |
| JP2015087167A (ja) * | 2013-10-29 | 2015-05-07 | キヤノン株式会社 | 画像処理方法、画像処理システム |
| US10314648B2 (en) | 2013-12-13 | 2019-06-11 | The Trustees of the Universoty of Pennsylvania | Coaxial ablation probe and method and system for real-time monitoring of ablation therapy |
| WO2015171543A1 (en) | 2014-05-05 | 2015-11-12 | California Institute Of Technology | Mutant akt-specific capture agents, compositions, and methods of using and making |
| WO2015196208A2 (en) | 2014-06-20 | 2015-12-23 | The General Hospital Corporation | Collagen targeted imaging probes |
| US9913875B2 (en) | 2015-03-16 | 2018-03-13 | California Institute Of Technology | Botulinum neurotoxin-specific capture agents, compositions, and methods of using and making |
| US10598671B2 (en) | 2015-07-15 | 2020-03-24 | Indi Molecular, Inc. | IL-17F-specific capture agents, compositions, and methods of using and making |
| US10383590B2 (en) | 2015-09-28 | 2019-08-20 | General Electric Company | Methods and systems for adaptive scan control |
| EP3519425B1 (en) | 2016-09-29 | 2024-02-28 | Indi Molecular, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same |
| US11358982B2 (en) | 2016-11-01 | 2022-06-14 | Ohio State Innovation Foundation | Methods for the iodination of biomolecules |
| EP3638687A1 (en) | 2017-06-15 | 2020-04-22 | Indi Molecular, Inc. | Il-17f and il-17a-specific capture agents, compositions, and methods of using and making |
| US20190370956A1 (en) | 2018-05-30 | 2019-12-05 | General Electric Company | Contrast imaging system and method |
| WO2020093055A2 (en) | 2018-11-02 | 2020-05-07 | Indi Molecular, Inc. | Peptide libraries with non-canonical amino acids |
| US11638764B2 (en) | 2018-11-08 | 2023-05-02 | Indi Molecular, Inc. | Theranostic capture agents, compositions, and methods of using and making |
| US12201679B2 (en) | 2019-04-05 | 2025-01-21 | Institute For Systems Biology | Epitope-targeted peptide immunostimulants |
| WO2020236969A1 (en) | 2019-05-20 | 2020-11-26 | Indi Molecular, Inc. | Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1) |
| US11414460B2 (en) | 2019-07-19 | 2022-08-16 | Institute For Systems Biology | KRAS-specific capture agents, compositions, and methods of making and using |
| US12209142B2 (en) | 2020-05-29 | 2025-01-28 | Institute For Systems Biology | SARS-CoV-2 epitope-targeted peptide immunostimulants |
| WO2022098743A1 (en) | 2020-11-03 | 2022-05-12 | Indi Molecular, Inc. | Compositions, imaging, and therapeutic methods targeting folate receptor 1 (folr1) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5250285A (en) | 1985-05-08 | 1993-10-05 | The General Hospital Corporation | Hydroxy-aryl metal chelates for diagnostic NMR imaging |
| US5094848A (en) | 1989-06-30 | 1992-03-10 | Neorx Corporation | Cleavable diphosphate and amidated diphosphate linkers |
| IT1269839B (it) | 1994-05-26 | 1997-04-15 | Bracco Spa | Coniugati di acidi biliari, loro derivati con complessi metallici e relativi usi |
| TW319763B (enExample) * | 1995-02-01 | 1997-11-11 | Epix Medical Inc | |
| CA2539215A1 (en) | 1995-02-01 | 1996-08-08 | Epix Pharmaceuticals, Inc. | Diagnostic imaging contrast agents with extended blood retention |
| DE19529512C2 (de) | 1995-08-10 | 2000-11-23 | Siemens Ag | Verfahren zur Phasenkontrast-MR-Angiographie und Anordnung zur Durchführung des Verfahrens |
| DE19543785A1 (de) | 1995-11-24 | 1997-05-28 | Philips Patentverwaltung | MR-Verfahren und Anordnung zur Durchführung des Verfahrens |
| PT907379E (pt) * | 1996-04-01 | 2004-09-30 | Epix Medical Inc | Agentes de contraste bioactivados para imagiologia de diagnostico |
| IT1283650B1 (it) | 1996-08-02 | 1998-04-23 | Bracco Spa | Chelati paramagnetici ad alta relassivita' in siero |
| US5919967A (en) | 1997-04-11 | 1999-07-06 | Epix Medical, Inc. | Process for synthesizing phosphodiesters |
| DE69819925T2 (de) * | 1997-10-02 | 2004-09-02 | Epix Medical, Inc., Cambridge | Kontrastverstärktes Diagnosebildererzeugungsverfahren zur Überwachung von therapeutischen Eingriffen |
| IT1304501B1 (it) | 1998-12-23 | 2001-03-19 | Bracco Spa | Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza |
-
1998
- 1998-09-24 DE DE69819925T patent/DE69819925T2/de not_active Expired - Lifetime
- 1998-09-24 IL IL13498598A patent/IL134985A0/xx not_active IP Right Cessation
- 1998-09-24 HU HU0101245A patent/HUP0101245A3/hu unknown
- 1998-09-24 AU AU96686/98A patent/AU742438C/en not_active Ceased
- 1998-09-24 ES ES98950704T patent/ES2206996T3/es not_active Expired - Lifetime
- 1998-09-24 BR BR9812716-0A patent/BR9812716A/pt not_active Application Discontinuation
- 1998-09-24 NZ NZ503402A patent/NZ503402A/en unknown
- 1998-09-24 KR KR1020007003527A patent/KR20010030854A/ko not_active Ceased
- 1998-09-24 CA CA002303426A patent/CA2303426C/en not_active Expired - Fee Related
- 1998-09-24 AT AT98950704T patent/ATE254479T1/de not_active IP Right Cessation
- 1998-09-24 JP JP2000514677A patent/JP2001518523A/ja active Pending
- 1998-09-24 WO PCT/US1998/020182 patent/WO1999017809A2/en not_active Ceased
- 1998-09-24 EP EP98950704A patent/EP1019094B1/en not_active Expired - Lifetime
- 1998-09-24 DK DK98950704T patent/DK1019094T3/da active
- 1998-09-24 PT PT98950704T patent/PT1019094E/pt unknown
- 1998-09-24 SK SK484-2000A patent/SK4842000A3/sk unknown
-
2000
- 2000-03-10 IS IS5399A patent/IS2041B/is unknown
- 2000-04-03 NO NO20001707A patent/NO321966B1/no not_active IP Right Cessation
- 2000-09-08 US US09/887,706 patent/US6861045B1/en not_active Expired - Fee Related
-
2004
- 2004-10-08 US US10/961,872 patent/US7175829B2/en not_active Expired - Fee Related
-
2005
- 2005-09-22 JP JP2005276942A patent/JP2006077020A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2001518523A5 (enExample) | ||
| US6652835B1 (en) | Targeting multimeric imaging agents through multilocus binding | |
| US5128121A (en) | Mixture of a positive and negative contrast agent for magnetic resonance imaging | |
| JP2003505519A5 (enExample) | ||
| US7727512B2 (en) | Chelating agents with lipophilic carriers | |
| CA1264663A (en) | Hepatobiliary nmr contrast agents | |
| CA2474386A1 (en) | Integrin targeted imaging agents | |
| WO2002028441A3 (en) | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits | |
| JPH0645632B2 (ja) | Mr像形成用ジアミド―dtpa―常磁性造影剤 | |
| JP2001518523A (ja) | インターベンショナル療法をモニタリングするためのコントラスト増強型診断的画像化方法 | |
| CA2108362A1 (en) | Melanin-based agents for image enhancement | |
| JP2004504363A (ja) | 拡張有機コバルトおよびニッケル磁性複合体 | |
| Nwe et al. | A new approach in the preparation of dendrimer-based bifunctional diethylenetriaminepentaacetic acid MR contrast agent derivatives | |
| AU732900B2 (en) | Liver function test | |
| JP5563299B2 (ja) | リンパ系撮像方法 | |
| JP4891763B2 (ja) | 「cest」用途のための、磁気共鳴シフト試薬と交換性プロトンを含有する基質との付加物 | |
| CA2514201A1 (en) | Chelating agents with lipophilic carriers | |
| CN100459932C (zh) | 一种mri分子影像探针及其制备方法 | |
| Giardiello et al. | Synthesis of lanthanide (III) complexes appended with a diphenylphosphinamide and their interaction with human serum albumin | |
| US5961953A (en) | Magnetic resonance blood pool agents | |
| Chakravarty et al. | Magnets, Magnetism, and Magnetic Resonance Imaging: History, Basics, Clinical Aspects, and Future Directions | |
| US20050201943A1 (en) | Magnetic resonance imaging using contrast agents bioactivated by enzymatic cleavage | |
| WO1997030734A1 (en) | Magnetic resonance blood pool agents | |
| US5693308A (en) | Magnetic resonance blood pool agents bound to human serum albumin | |
| Fransen et al. | r1 and r2 Relaxivities of Dendrons Based on a OEG‐DTPA Architecture: Effect of Gd3+ Placement and Dendron Functionalization |