JP2001510982A5 - - Google Patents

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Publication number
JP2001510982A5
JP2001510982A5 JP1997526921A JP52692197A JP2001510982A5 JP 2001510982 A5 JP2001510982 A5 JP 2001510982A5 JP 1997526921 A JP1997526921 A JP 1997526921A JP 52692197 A JP52692197 A JP 52692197A JP 2001510982 A5 JP2001510982 A5 JP 2001510982A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997526921A
Other languages
English (en)
Japanese (ja)
Other versions
JP4018142B2 (ja
JP2001510982A (ja
Filing date
Publication date
Priority claimed from US08/618,957 external-priority patent/US6355237B1/en
Application filed filed Critical
Priority claimed from PCT/US1997/000767 external-priority patent/WO1997027286A1/en
Publication of JP2001510982A publication Critical patent/JP2001510982A/ja
Publication of JP2001510982A5 publication Critical patent/JP2001510982A5/ja
Application granted granted Critical
Publication of JP4018142B2 publication Critical patent/JP4018142B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP52692197A 1996-01-23 1997-01-21 造血発生を刺激するためのobese遺伝子およびその産物の使用方法 Expired - Fee Related JP4018142B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US58991596A 1996-01-23 1996-01-23
US08/618,957 US6355237B1 (en) 1994-09-14 1996-03-20 Methods for using the obese gene and its gene product to stimulate hematopoietic development
US71329696A 1996-09-13 1996-09-13
US08/713,296 1996-09-13
US08/618,957 1996-09-13
US08/589,915 1996-09-13
PCT/US1997/000767 WO1997027286A1 (en) 1996-01-23 1997-01-21 Methods for using the obese gene and its gene product to stimulate hematopoietic development

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2006355150A Division JP2007163502A (ja) 1996-01-23 2006-12-28 造血発生を刺激するためのobese遺伝子およびその産物の使用方法

Publications (3)

Publication Number Publication Date
JP2001510982A JP2001510982A (ja) 2001-08-07
JP2001510982A5 true JP2001510982A5 (https=) 2004-11-11
JP4018142B2 JP4018142B2 (ja) 2007-12-05

Family

ID=27416556

Family Applications (2)

Application Number Title Priority Date Filing Date
JP52692197A Expired - Fee Related JP4018142B2 (ja) 1996-01-23 1997-01-21 造血発生を刺激するためのobese遺伝子およびその産物の使用方法
JP2006355150A Pending JP2007163502A (ja) 1996-01-23 2006-12-28 造血発生を刺激するためのobese遺伝子およびその産物の使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2006355150A Pending JP2007163502A (ja) 1996-01-23 2006-12-28 造血発生を刺激するためのobese遺伝子およびその産物の使用方法

Country Status (10)

Country Link
EP (2) EP1731164A1 (https=)
JP (2) JP4018142B2 (https=)
AT (1) ATE320479T1 (https=)
AU (1) AU731685C (https=)
CA (1) CA2244693A1 (https=)
DE (1) DE69735477T2 (https=)
DK (1) DK0892849T3 (https=)
ES (1) ES2260784T3 (https=)
PT (1) PT892849E (https=)
WO (1) WO1997027286A1 (https=)

Families Citing this family (32)

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US6001968A (en) * 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
DK0877803T3 (da) * 1996-01-04 2005-09-19 Amgen Inc OB-proteinreceptor og relaterede sammensætninger og fremgangsmåder
US20050019325A1 (en) 1996-01-08 2005-01-27 Carter Paul J. WSX receptor agonist antibodies
US7074397B1 (en) 1996-01-08 2006-07-11 Genentech, Inc. Method for enhancing proliferation or differentiation of a cell using ob protein
US6541604B1 (en) 1996-01-08 2003-04-01 Genentech, Inc. Leptin receptor having a WSX motif
IL120733A0 (en) * 1997-04-29 1997-08-14 Yeda Res & Dev Leptin as an inhibitor of cell proliferation
FR2767136B1 (fr) * 1997-08-06 2004-08-27 Genset Sa Recepteur complexe lsr, activite, clonage, et applications au diagnostic, a la prevention et/ou au traitement de l'obesite et des risques ou complications associes
FR2767135B1 (fr) 1997-08-06 2002-07-12 Genset Sa Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes
AU4672199A (en) * 1998-05-20 1999-12-06 Yale University Modulation of angiogenesis and wound healing
US7208572B2 (en) 1998-08-21 2007-04-24 Albany Medical College Leptin-related peptides
US6777388B1 (en) 1998-08-21 2004-08-17 Clf Medical Technology Acceleration Program, Inc. Leptin-related peptides
CA2341754A1 (en) * 1998-08-31 2000-03-09 New York University Stem cells bearing an fgf receptor on the cell surface
ES2308852T3 (es) 1998-11-04 2008-12-01 Serono Genetics Inst Sa Secuencias genomicas y completas de cdna de apm1 humano especifico para adipocitos y marcadores bialelicos de los mismos.
DE60041912D1 (de) 1999-02-10 2009-05-14 Serono Genetics Inst Sa Polymorphe marker des lsr-gens
US20050272652A1 (en) 1999-03-29 2005-12-08 Gault Victor A Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
IL132312A0 (en) * 1999-09-05 2001-03-19 Yeda Res & Dev Use of leptin in inhibition of endothelial cell proliferation
US6989367B2 (en) 2000-01-14 2006-01-24 Genset S.A. OBG3 globular head and uses thereof
US6566332B2 (en) 2000-01-14 2003-05-20 Genset S.A. OBG3 globular head and uses thereof for decreasing body mass
US20020058617A1 (en) 2000-01-14 2002-05-16 Joachim Fruebis OBG3 globular head and uses thereof for decreasing body mass
US7338787B2 (en) 2000-01-14 2008-03-04 Serono Genetics Institute S.A. Nucleic acids encoding OBG3 globular head and uses thereof
US8076288B2 (en) 2004-02-11 2011-12-13 Amylin Pharmaceuticals, Inc. Hybrid polypeptides having glucose lowering activity
EP1718665B1 (en) 2004-02-11 2013-04-10 Amylin Pharmaceuticals, LLC Hybrid polypeptides with selectable properties
US8263545B2 (en) 2005-02-11 2012-09-11 Amylin Pharmaceuticals, Inc. GIP analog and hybrid polypeptides with selectable properties
BRPI0606992A2 (pt) 2005-02-11 2009-07-28 Amylin Pharmaceuticals Inc análogo e polipeptìdeos hìbridos de gip com propriedades selecionáveis
BRPI0614649A2 (pt) 2005-08-11 2011-04-12 Amylin Pharmaceuticals Inc polipeptìdeos hìbridos com propriedades selecionáveis
EP2330124B1 (en) 2005-08-11 2015-02-25 Amylin Pharmaceuticals, LLC Hybrid polypeptides with selectable properties
US8497240B2 (en) 2006-08-17 2013-07-30 Amylin Pharmaceuticals, Llc DPP-IV resistant GIP hybrid polypeptides with selectable properties
TW202417497A (zh) 2015-10-12 2024-05-01 美商再生元醫藥公司 活化瘦素受體的抗原結合蛋白
US10550192B2 (en) 2016-11-08 2020-02-04 Regeneron Pharmaceuticals, Inc. Antigen-binding proteins that antagonize leptin receptor
WO2019126071A1 (en) 2017-12-18 2019-06-27 Regeneron Pharmaceuticals, Inc. Bispecific antigen binding molecules that bind leptin receptor and/or gp130, and methods of use thereof
DK3773713T3 (da) 2018-04-06 2025-08-18 Regeneron Pharma Leptinreceptoragonistantistof til anvendelse i forøgelse af knoglemasse hos et individ, der lider af metabolisk dysfunktion eller hypoleptinæmI
US20210228685A1 (en) * 2018-07-24 2021-07-29 Bioreg Llc Improved weight loss therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643748A (en) * 1994-09-14 1997-07-01 Progenitor, Inc. HU-B1.219, a novel human hematopoietin receptor

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