ES2308852T3 - Secuencias genomicas y completas de cdna de apm1 humano especifico para adipocitos y marcadores bialelicos de los mismos. - Google Patents

Secuencias genomicas y completas de cdna de apm1 humano especifico para adipocitos y marcadores bialelicos de los mismos. Download PDF

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Publication number
ES2308852T3
ES2308852T3 ES99954295T ES99954295T ES2308852T3 ES 2308852 T3 ES2308852 T3 ES 2308852T3 ES 99954295 T ES99954295 T ES 99954295T ES 99954295 T ES99954295 T ES 99954295T ES 2308852 T3 ES2308852 T3 ES 2308852T3
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ES
Spain
Prior art keywords
markers
apm1
genomic
provides
bialelic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99954295T
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English (en)
Inventor
Isabelle Dufaure-Gare
Lydie Bougueleret
Marta Blumenfeld
Bernard Bihain
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Merck Biodevelopment SAS
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Serono Genetics Institute SA
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Publication date
Application filed by Serono Genetics Institute SA filed Critical Serono Genetics Institute SA
Application granted granted Critical
Publication of ES2308852T3 publication Critical patent/ES2308852T3/es
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Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/927—Diagnostic contrast agent
    • Y10S977/928—X-ray agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Un polinucleótido aislado, purificado o recombinante que consiste en un tramo contiguo de 8 a 50 nucleótidos del SEQ ID NO: 1 o su complemento, en el que dicho tramo incluye un marcador bialélico relacionado con APM1 en dicha secuencia, en el que dicho marcador bialélico relacionado con APM1 se selecciona entre el grupo que consiste en A1 (SEQ ID NO: 1, posición 3.787), A2 (SEQ ID NO: 1, posición 11.118), A4 (SEQ ID NO: 1, posición 15.196), A7 (SEQ ID NO: 1, posición 15.863) y A8 (SEQ ID NO: 1, posición 17.170).
ES99954295T 1998-11-04 1999-11-04 Secuencias genomicas y completas de cdna de apm1 humano especifico para adipocitos y marcadores bialelicos de los mismos. Expired - Lifetime ES2308852T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10711398P 1998-11-04 1998-11-04
US11959399P 1999-02-10 1999-02-10

Publications (1)

Publication Number Publication Date
ES2308852T3 true ES2308852T3 (es) 2008-12-01

Family

ID=26804398

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99954295T Expired - Lifetime ES2308852T3 (es) 1998-11-04 1999-11-04 Secuencias genomicas y completas de cdna de apm1 humano especifico para adipocitos y marcadores bialelicos de los mismos.

Country Status (9)

Country Link
US (3) US6582909B1 (es)
EP (1) EP1127120B1 (es)
JP (1) JP2002528118A (es)
AT (1) ATE397064T1 (es)
AU (1) AU772243B2 (es)
CA (1) CA2348828C (es)
DE (1) DE69938837D1 (es)
ES (1) ES2308852T3 (es)
WO (1) WO2000026363A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002006525A2 (en) * 2000-07-18 2002-01-24 Genset S.A. Obesity associated biallelic marker maps
US6829589B1 (en) 2000-07-21 2004-12-07 Stc, Llc Method and apparatus for stock and index option price improvement, participation, and internalization
CN1886423A (zh) * 2002-01-18 2006-12-27 普罗特米克斯公司 脂联素的糖基同工型及其用途
EP1577388B1 (en) 2002-12-26 2011-02-16 Ono Pharmaceutical Co., Ltd. Adiponectin promoter and use thereof
HUE032575T2 (en) 2003-05-21 2017-10-30 Andes Biotechnologies S A Compounds and Oligonucleotides for Diagnosis and Treatment of Cancer and Cancer Prevention
WO2005013091A2 (en) * 2003-08-01 2005-02-10 New York University Methods, software arrangements, storage media, and systems for genotyping or haplotyping polymorphic genetic loci or strain identification
WO2005094866A1 (ja) * 2004-03-31 2005-10-13 Toudai Tlo, Ltd. アディポネクチン発現誘導剤およびその利用
EP1830873A4 (en) * 2004-12-10 2008-04-02 Protemix Corp Ltd GLYPONECTIN (ADIPONECTIN GLYCOSYLE) FOR THE TREATMENT OF DISEASES AND CONDITIONS
US8685642B2 (en) * 2007-07-30 2014-04-01 Agilent Technologies, Inc. Allele-specific copy number measurement using single nucleotide polymorphism and DNA arrays
CN111269978B (zh) * 2020-03-27 2020-12-08 深圳市天大生物医疗器械有限公司 一种人ApoE基因分型检测试剂盒

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
DE3924454A1 (de) * 1989-07-24 1991-02-07 Cornelis P Prof Dr Hollenberg Die anwendung von dna und dna-technologie fuer die konstruktion von netzwerken zur verwendung in der chip-konstruktion und chip-produktion (dna chips)
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5270170A (en) 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
US6140466A (en) 1994-01-18 2000-10-31 The Scripps Research Institute Zinc finger protein derivatives and methods therefor
US5691447A (en) 1995-03-24 1997-11-25 Tanox Biosystems, Inc. GC1q receptor, HIV-1 gp120 region binding thereto, and related peptides and targeting antibodies
FR2733762B1 (fr) 1995-05-02 1997-08-01 Genset Sa Methode de couplage specifique de la coiffe de l'extremite 5' d'un fragment d'arnm et preparation d'arnm et d'adnc complet
US5869330A (en) * 1995-06-05 1999-02-09 Whitehead Institute For Biomedical Research DNA encoding a novel serum protein produced exclusively in adipocytes
WO1997027286A1 (en) 1996-01-23 1997-07-31 Progenitor, Inc. Methods for using the obese gene and its gene product to stimulate hematopoietic development
EP0910374A1 (de) 1996-07-13 1999-04-28 Roche Diagnostics GmbH Topisch einsetzbare pharmazeutische formulierungen enthaltend als wirkstoff ein carbazolyl-(4)-oxy-propanolamin-derivat
EP0941366A2 (en) 1996-11-06 1999-09-15 Whitehead Institute For Biomedical Research Biallelic markers
FR2767135B1 (fr) * 1997-08-06 2002-07-12 Genset Sa Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes
CA2301660A1 (en) * 1997-08-26 1999-03-04 Zymogenetics, Inc. Adipocyte-specific protein homologs
WO1999021577A1 (fr) * 1997-10-29 1999-05-06 Otsuka Pharmaceutical Co., Ltd. Compositions inhibant la proliferation des muscles lisses, procede de diagnostic de l'arteriosclerose et trousses correspondantes
US6566332B2 (en) * 2000-01-14 2003-05-20 Genset S.A. OBG3 globular head and uses thereof for decreasing body mass
US6579852B2 (en) * 2000-01-14 2003-06-17 Genset S.A. OBG3 globular head and uses thereof for decreasing body mass
US20020058617A1 (en) * 2000-01-14 2002-05-16 Joachim Fruebis OBG3 globular head and uses thereof for decreasing body mass
US7338787B2 (en) * 2000-01-14 2008-03-04 Serono Genetics Institute S.A. Nucleic acids encoding OBG3 globular head and uses thereof
US6989367B2 (en) * 2000-01-14 2006-01-24 Genset S.A. OBG3 globular head and uses thereof

Also Published As

Publication number Publication date
US20030165967A1 (en) 2003-09-04
ATE397064T1 (de) 2008-06-15
WO2000026363A1 (en) 2000-05-11
US6582909B1 (en) 2003-06-24
EP1127120B1 (en) 2008-05-28
JP2002528118A (ja) 2002-09-03
CA2348828C (en) 2009-09-15
CA2348828A1 (en) 2000-05-11
AU772243B2 (en) 2004-04-22
AU1070300A (en) 2000-05-22
US20060166259A1 (en) 2006-07-27
EP1127120A1 (en) 2001-08-29
DE69938837D1 (de) 2008-07-10

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