JP2001510164A - 動物に対する毒性を減じた生物活性ペプチドおよび同ペプチドを調製する方法。 - Google Patents

動物に対する毒性を減じた生物活性ペプチドおよび同ペプチドを調製する方法。

Info

Publication number
JP2001510164A
JP2001510164A JP2000502785A JP2000502785A JP2001510164A JP 2001510164 A JP2001510164 A JP 2001510164A JP 2000502785 A JP2000502785 A JP 2000502785A JP 2000502785 A JP2000502785 A JP 2000502785A JP 2001510164 A JP2001510164 A JP 2001510164A
Authority
JP
Japan
Prior art keywords
peptide
amino acid
hydrophilic
protein
neutral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000502785A
Other languages
English (en)
Japanese (ja)
Inventor
ユー．， プラサド カリ，
タフィー， ジェイ． ウィリアムズ，
マイケル マクレーン，
Original Assignee
マガイニン ファーマシューティカルズ インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マガイニン ファーマシューティカルズ インコーポレイテッド filed Critical マガイニン ファーマシューティカルズ インコーポレイテッド
Publication of JP2001510164A publication Critical patent/JP2001510164A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Insects & Arthropods (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2000502785A 1997-07-15 1998-07-15 動物に対する毒性を減じた生物活性ペプチドおよび同ペプチドを調製する方法。 Withdrawn JP2001510164A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89300697A 1997-07-15 1997-07-15
US08/893,006 1997-07-15
PCT/US1998/014610 WO1999003488A2 (fr) 1997-07-15 1998-07-15 Peptides biologiquement actifs a toxicite reduite chez l'animal et procedes d'elaboration

Publications (1)

Publication Number Publication Date
JP2001510164A true JP2001510164A (ja) 2001-07-31

Family

ID=25400865

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000502785A Withdrawn JP2001510164A (ja) 1997-07-15 1998-07-15 動物に対する毒性を減じた生物活性ペプチドおよび同ペプチドを調製する方法。

Country Status (5)

Country Link
EP (1) EP1001800A2 (fr)
JP (1) JP2001510164A (fr)
AU (1) AU8300598A (fr)
CA (1) CA2294518A1 (fr)
WO (1) WO1999003488A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010516688A (ja) 2007-01-16 2010-05-20 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 抗菌ペプチド
US7960336B2 (en) 2007-08-03 2011-06-14 Pharmain Corporation Composition for long-acting peptide analogs
KR101749310B1 (ko) 2008-01-24 2017-06-21 에스퍼란스 파마슈티컬스, 인코포레이티드 용해 도메인 융합 구성물 및 이를 제조하고 사용하는 방법
DK2914633T3 (da) 2012-10-30 2022-03-14 Esperance Pharmaceuticals Inc Antistof/lægemiddel-konjugater og anvendelsesfremgangsmåder

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU674525B2 (en) * 1992-06-01 1997-01-02 Magainin Pharmaceuticals, Inc. Biologically active peptides having N-terminal substitutions
AU693518B2 (en) * 1994-01-18 1998-07-02 Magainin Pharmaceuticals, Inc. Ion-channel forming amphiphilic peptides having n-terminal modifications

Also Published As

Publication number Publication date
EP1001800A2 (fr) 2000-05-24
AU8300598A (en) 1999-02-10
CA2294518A1 (fr) 1999-01-28
WO1999003488A3 (fr) 1999-04-08
WO1999003488A2 (fr) 1999-01-28

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Legal Events

Date Code Title Description
A300 Withdrawal of application because of no request for examination

Free format text: JAPANESE INTERMEDIATE CODE: A300

Effective date: 20051004