|
US7812149B2
(en)
|
1996-06-06 |
2010-10-12 |
Isis Pharmaceuticals, Inc. |
2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
|
|
US5898031A
(en)
|
1996-06-06 |
1999-04-27 |
Isis Pharmaceuticals, Inc. |
Oligoribonucleotides for cleaving RNA
|
|
US9096636B2
(en)
|
1996-06-06 |
2015-08-04 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
|
GB9621367D0
(en)
*
|
1996-10-14 |
1996-12-04 |
Isis Innovation |
Chiral peptide nucleic acids
|
|
US6326479B1
(en)
*
|
1998-01-27 |
2001-12-04 |
Boston Probes, Inc. |
Synthetic polymers and methods, kits or compositions for modulating the solubility of same
|
|
EP1156781B1
(en)
|
1999-02-26 |
2005-06-08 |
Chiron Corporation |
Microemulsions with adsorbed macromolecules and microparticles
|
|
US20040063906A1
(en)
*
|
2000-11-24 |
2004-04-01 |
Nielsen Peter E. |
Pna analogues
|
|
WO2002053574A2
(en)
*
|
2001-01-05 |
2002-07-11 |
Pantheco A/S |
Modified pna molecules
|
|
US6716961B2
(en)
*
|
2001-10-30 |
2004-04-06 |
Isis Innovation Limited |
Chiral peptide nucleic acids with a N-aminoethyl-d-proline backbone
|
|
ES2316776T3
(es)
*
|
2002-02-04 |
2009-04-16 |
Isis Innovation Limited |
Acidos nucleicos de peptidos de pirrolidinilo.
|
|
AU2003291755A1
(en)
*
|
2002-11-05 |
2004-06-07 |
Isis Pharmaceuticals, Inc. |
Oligomers comprising modified bases for binding cytosine and uracil or thymine and their use
|
|
ATE488604T1
(de)
*
|
2003-05-20 |
2010-12-15 |
Investigen Inc |
System zum nachweis von polynukleotiden
|
|
EP1644475A4
(en)
|
2003-06-20 |
2009-06-03 |
Isis Pharmaceuticals Inc |
DOUBLE-STRAND COMPOSITIONS WITH A 3'-ENDO-MODIFIED STRING FOR USE IN GENE MODULATION
|
|
US8569474B2
(en)
|
2004-03-09 |
2013-10-29 |
Isis Pharmaceuticals, Inc. |
Double stranded constructs comprising one or more short strands hybridized to a longer strand
|
|
US8394947B2
(en)
|
2004-06-03 |
2013-03-12 |
Isis Pharmaceuticals, Inc. |
Positionally modified siRNA constructs
|
|
US7884086B2
(en)
|
2004-09-08 |
2011-02-08 |
Isis Pharmaceuticals, Inc. |
Conjugates for use in hepatocyte free uptake assays
|
|
US8021839B2
(en)
*
|
2006-02-24 |
2011-09-20 |
Investigen, Inc. |
Methods and compositions for detecting polynucleotides
|
|
US20080096193A1
(en)
*
|
2006-10-24 |
2008-04-24 |
Charles Robert Bupp |
Methods and compositions for detecting polynucleotides
|
|
EP2099816A1
(en)
*
|
2006-12-04 |
2009-09-16 |
Luminex Corporation |
Oxocarbonamide peptide nucleic acids and methods of using same
|
|
US7771947B2
(en)
*
|
2007-02-23 |
2010-08-10 |
Investigen, Inc. |
Methods and compositions for rapid light-activated isolation and detection of analytes
|
|
US7964355B2
(en)
*
|
2009-02-17 |
2011-06-21 |
Investigen, Inc. |
Assays based on detection of photobleaching reaction products from dye catalytic complex
|
|
EP2933333B1
(en)
|
2010-07-08 |
2018-02-21 |
Bonac Corporation |
Single-strand nucleic acid molecule for controlling gene expression
|
|
EP2639307B1
(en)
|
2010-08-03 |
2015-03-04 |
Bonac Corporation |
Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton
|
|
WO2013180038A1
(ja)
|
2012-05-26 |
2013-12-05 |
株式会社ボナック |
デリバリー機能を有する遺伝子発現制御用の一本鎖核酸分子
|
|
WO2015099122A1
(ja)
|
2013-12-26 |
2015-07-02 |
学校法人東京医科大学 |
遺伝子発現制御のための人工ミミックmiRNAおよびその用途
|
|
CN106068324B
(zh)
|
2013-12-27 |
2020-12-29 |
株式会社博纳克 |
控制基因表达的人工匹配型miRNA及其用途
|
|
KR20170098914A
(ko)
|
2014-12-27 |
2017-08-30 |
가부시키가이샤 보낙 |
유전자 발현 제어를 위한 천연형 miRNA 및 그의 용도
|
|
WO2016158809A1
(ja)
|
2015-03-27 |
2016-10-06 |
株式会社ボナック |
デリバリー機能と遺伝子発現制御能を有する一本鎖核酸分子
|