JP2001501170A5 - - Google Patents
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- Publication number
- JP2001501170A5 JP2001501170A5 JP1997537864A JP53786497A JP2001501170A5 JP 2001501170 A5 JP2001501170 A5 JP 2001501170A5 JP 1997537864 A JP1997537864 A JP 1997537864A JP 53786497 A JP53786497 A JP 53786497A JP 2001501170 A5 JP2001501170 A5 JP 2001501170A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9608457.9A GB9608457D0 (en) | 1996-04-24 | 1996-04-24 | Inhibitors of proteolytic enzymes |
| GB9608457.9 | 1996-04-24 | ||
| GB9616115.3 | 1996-07-31 | ||
| GBGB9616115.3A GB9616115D0 (en) | 1996-07-31 | 1996-07-31 | Substrate and inhibitors of proteolytic enzymes |
| GBGB9624584.0A GB9624584D0 (en) | 1996-11-27 | 1996-11-27 | Substances and inhibitors of proteolytic enzymes |
| GB9624584.0 | 1996-11-27 | ||
| PCT/GB1997/001157 WO1997040065A2 (en) | 1996-04-24 | 1997-04-24 | Substrates and inhibitors of proteolytic enzymes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001501170A JP2001501170A (ja) | 2001-01-30 |
| JP2001501170A5 true JP2001501170A5 (enExample) | 2005-01-13 |
| JP4215822B2 JP4215822B2 (ja) | 2009-01-28 |
Family
ID=27268257
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP09539622A Abandoned JP2000512979A (ja) | 1996-04-24 | 1997-04-24 | 自己デコンボリューション法によるコンビナトリアルライブラリー |
| JP53786497A Expired - Fee Related JP4215822B2 (ja) | 1996-04-24 | 1997-04-24 | タンパク質分解酵素の基質および阻害剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP09539622A Abandoned JP2000512979A (ja) | 1996-04-24 | 1997-04-24 | 自己デコンボリューション法によるコンビナトリアルライブラリー |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6528275B1 (enExample) |
| EP (2) | EP0906333B1 (enExample) |
| JP (2) | JP2000512979A (enExample) |
| AT (1) | ATE203545T1 (enExample) |
| AU (2) | AU706855B2 (enExample) |
| CA (2) | CA2252508A1 (enExample) |
| DE (1) | DE69705838T2 (enExample) |
| DK (1) | DK0906333T3 (enExample) |
| ES (1) | ES2162277T3 (enExample) |
| WO (2) | WO1997040065A2 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6042789A (en) * | 1996-10-23 | 2000-03-28 | Glaxo Group Limited | System for parallel synthesis of organic compounds |
| US6149869A (en) * | 1996-10-23 | 2000-11-21 | Glaxo Wellcome Inc. | Chemical synthesizers |
| US6617114B1 (en) | 1996-10-31 | 2003-09-09 | Karo Bio Ab | Identification of drug complementary combinatorial libraries |
| JP2001510453A (ja) * | 1996-10-31 | 2001-07-31 | ノヴァロン ファーマスーチカル コーポレイション | 相補的組み合わせライブラリーを使用する薬剤の同定 |
| US6054325A (en) * | 1996-12-02 | 2000-04-25 | Glaxo Wellcom Inc. | Method and apparatus for transferring and combining distinct chemical compositions with reagents |
| US6083761A (en) * | 1996-12-02 | 2000-07-04 | Glaxo Wellcome Inc. | Method and apparatus for transferring and combining reagents |
| GB9722818D0 (en) * | 1997-10-30 | 1997-12-24 | Peptide Therapeutics Ltd | A method for mapping the active sites bound by enzymes that covalently modify substrate molecules |
| EP1034154A1 (en) * | 1997-11-26 | 2000-09-13 | Peptide Therapeutics Limited | A solid-phase technology for the preparation of combinatorial libraries through amide-bond anchoring |
| US6083682A (en) | 1997-12-19 | 2000-07-04 | Glaxo Group Limited | System and method for solid-phase parallel synthesis of a combinatorial collection of compounds |
| MY153569A (en) | 1998-01-20 | 2015-02-27 | Mitsubishi Tanabe Pharma Corp | Inhibitors of ?4 mediated cell adhesion |
| US6569636B2 (en) | 1998-05-29 | 2003-05-27 | Hawaii Biotechnology Group, Inc. | Assay for modulators of metallo-enzyme activity |
| DE19925402C2 (de) * | 1999-06-02 | 2001-12-20 | Molecular Machines & Ind Gmbh | Screening von Target-Ligand-Wechselwirkungen |
| CA2398583A1 (en) | 2000-02-11 | 2001-08-16 | Cellomics, Inc. | Peptide biosensors for anthrax protease |
| JP2002250730A (ja) * | 2001-02-27 | 2002-09-06 | Shinwa Kako Kk | 分子センサー及びその製造方法 |
| MY140707A (en) | 2002-02-28 | 2010-01-15 | Mitsubishi Tanabe Pharma Corp | Process for preparing a phenylalanine derivative and intermediates thereof |
| PL374971A1 (en) * | 2002-08-09 | 2005-11-14 | Transtech Pharma, Inc. | Aryl and heteroaryl compounds and methods to modulate coagulation |
| US7208601B2 (en) * | 2003-08-08 | 2007-04-24 | Mjalli Adnan M M | Aryl and heteroaryl compounds, compositions, and methods of use |
| WO2005014532A1 (en) | 2003-08-08 | 2005-02-17 | Transtech Pharma, Inc. | Aryl and heteroaryl compounds, compositions and methods of use |
| US8015064B2 (en) * | 2005-04-20 | 2011-09-06 | At&T Intellectual Property I, Lp | System and method of providing advertisements to cellular devices |
| BRPI0615980A2 (pt) * | 2005-07-26 | 2011-05-31 | Council Scient Ind Res | método de identificação de genes que aumentam a toleráncia ao stress na levedura para melhorar a eficiência da levedura |
| EP2364366B1 (en) | 2008-11-05 | 2014-01-08 | MorphoSys AG | Deconvolution method |
| EP2189536A1 (en) * | 2008-11-20 | 2010-05-26 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Rapid FRET based anthrax diagnosis |
| JP5798487B2 (ja) * | 2008-11-20 | 2015-10-21 | ネーデルランドセ・オルガニサティ・フォール・トゥーヘパスト−ナトゥールウェテンスハッペライク・オンデルズーク・テーエヌオー | Ｆｒｅｔに基づく病原体の迅速診断 |
| KR102438072B1 (ko) | 2012-01-12 | 2022-08-31 | 예일 유니버시티 | E3 유비퀴틴 리가아제에 의한 표적 단백질 및 다른 폴리펩티드의 증진된 분해를 위한 화합물 및 방법 |
| GB201311888D0 (en) | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| GB201311891D0 (en) | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compound |
| US20180228907A1 (en) | 2014-04-14 | 2018-08-16 | Arvinas, Inc. | Cereblon ligands and bifunctional compounds comprising the same |
| CN108366992A (zh) | 2015-11-02 | 2018-08-03 | 耶鲁大学 | 蛋白水解靶向嵌合体化合物及其制备和应用方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0428000A1 (en) | 1989-11-03 | 1991-05-22 | Abbott Laboratories | Fluorogenic substrates for the detection of proteolytic enzyme activity |
| US5011910A (en) * | 1989-12-28 | 1991-04-30 | Washington University | Reagent and method for determining activity of retroviral protease |
| US5164300A (en) | 1989-12-28 | 1992-11-17 | Washington University | Method for determining activity of retroviral protease |
| DK93990D0 (da) | 1990-04-17 | 1990-04-17 | Carlsberg As | Fluorogene peptider og deres anvendelse ved bestemmelse af enzymatisk aktivitet |
| HU9201687D0 (en) | 1992-05-21 | 1992-08-28 | Arpad Furka | Preparation of sets from peptid mixtures with polycomponents and their use for the identification of biologically active peptides |
| US5585275A (en) * | 1992-09-02 | 1996-12-17 | Arris Pharmaceutical Corporation | Pilot apparatus for peptide synthesis and screening |
| DE69406806D1 (de) | 1993-12-15 | 1997-12-18 | Combichem Inc | Kombinatorische Bibliotheken und Verfahren zu ihrer Verwendung |
| US5506115A (en) | 1994-04-29 | 1996-04-09 | G. D. Searle & Co. | Reagent and method for determining activity of herpes protease |
| US5738996A (en) * | 1994-06-15 | 1998-04-14 | Pence, Inc. | Combinational library composition and method |
| EP1019528B1 (en) | 1996-01-04 | 2003-10-29 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Method for assaying proteolytic enzymes using fluorescence-quenched substrates |
| US7135288B2 (en) * | 2002-09-27 | 2006-11-14 | Ut-Battelle, Llc | Combinatorial synthesis of ceramic materials |
-
1997
- 1997-04-24 WO PCT/GB1997/001157 patent/WO1997040065A2/en not_active Ceased
- 1997-04-24 AU AU26449/97A patent/AU706855B2/en not_active Ceased
- 1997-04-24 ES ES97918252T patent/ES2162277T3/es not_active Expired - Lifetime
- 1997-04-24 CA CA002252508A patent/CA2252508A1/en not_active Abandoned
- 1997-04-24 EP EP97918252A patent/EP0906333B1/en not_active Expired - Lifetime
- 1997-04-24 AU AU26450/97A patent/AU728263B2/en not_active Ceased
- 1997-04-24 JP JP09539622A patent/JP2000512979A/ja not_active Abandoned
- 1997-04-24 AT AT97918252T patent/ATE203545T1/de not_active IP Right Cessation
- 1997-04-24 DK DK97918252T patent/DK0906333T3/da active
- 1997-04-24 US US09/171,680 patent/US6528275B1/en not_active Expired - Fee Related
- 1997-04-24 DE DE69705838T patent/DE69705838T2/de not_active Expired - Fee Related
- 1997-04-24 WO PCT/GB1997/001158 patent/WO1997042216A1/en not_active Ceased
- 1997-04-24 JP JP53786497A patent/JP4215822B2/ja not_active Expired - Fee Related
- 1997-04-24 CA CA002252408A patent/CA2252408A1/en not_active Abandoned
- 1997-04-24 EP EP97918253A patent/EP0906334A1/en not_active Withdrawn
-
2002
- 2002-09-30 US US10/259,420 patent/US20030092067A1/en not_active Abandoned