JP2001151688A - Stevia concentration solution agent and ointment for treating dermatosis and method for producing the same - Google Patents
Stevia concentration solution agent and ointment for treating dermatosis and method for producing the sameInfo
- Publication number
- JP2001151688A JP2001151688A JP33440099A JP33440099A JP2001151688A JP 2001151688 A JP2001151688 A JP 2001151688A JP 33440099 A JP33440099 A JP 33440099A JP 33440099 A JP33440099 A JP 33440099A JP 2001151688 A JP2001151688 A JP 2001151688A
- Authority
- JP
- Japan
- Prior art keywords
- stevia
- ointment
- ginseng
- extract
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は天然植物を原料とし
た液剤およびその製造方法に関するものであって、より
詳しくはステビア茎部からの抽出液を濃縮し、高麗人参
と混合し、熟成させて得られた液剤、更に日本薬局方親
水軟膏と該混合物を熟成させるその製造方法に関するも
のである。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a liquid preparation using a natural plant as a raw material and a method for producing the same. More specifically, the present invention relates to a method of concentrating an extract from the stem of Stevia, mixing it with ginseng, and aging it. The present invention relates to a liquid ointment obtained, a hydrophilic ointment of the Japanese Pharmacopoeia and a method for producing the mixture by aging the mixture.
【０００２】[0002]
【従来の技術】天然植物を原料として、該植物の抽出液
から医薬品、飲食物などの各種の有用なものを製造する
ことは古くから行われていた。そして、天然植物として
ステビアに着目し、該植物から甘味料、医薬品、皮膚治
療軟膏、浴用剤、あるいは園芸用肥料等を製造する技術
はすでに知られている。2. Description of the Related Art It has long been practiced to use a natural plant as a raw material to produce various useful products such as pharmaceuticals, foods and drinks from an extract of the plant. Attention has been paid to stevia as a natural plant, and techniques for producing sweeteners, pharmaceuticals, skin treatment ointments, bath agents, horticultural fertilizers, and the like from the plant are already known.
【０００３】例えば、本発明者によって開発された技術
として、特開平３−１２７９５９号公報には、ステビア
の甘葉からの抽出液を濃縮し熟成させて甘味料を製造す
る技術が開示させているのをはじめとして、特開平４−
６５３８０号公報、特開平４−６６５３５号公報、特開
平３−１５１３２１号公報、特願平３−２３０６３２号
には、それぞれステビア植物を原料とした園芸用肥料、
浴用剤、皮膚用外用剤、畜産用内服液を製造する技術を
提案している。[0003] For example, as a technique developed by the present inventors, Japanese Patent Application Laid-Open No. 3-127959 discloses a technique for producing a sweetener by concentrating and ripening an extract from stevia sweet leaves. And Japanese Patent Application Laid-Open
No. 65380, JP-A-4-66535, JP-A-3-151321, and Japanese Patent Application No. 3-230632 each disclose a horticultural fertilizer using a stevia plant as a raw material.
A technique for producing a bath agent, an external preparation for skin, and an internal liquid for livestock is proposed.
【０００４】[0004]
【発明が解決しようとする課題】また、さらに本発明者
は、ステビアを原料とした内服液を開発し、特願平３−
１９３３０１号として特許出願済（以下、先願発明とい
うことがある）であるが、この度、前記先願発明を追試
し、更に有用な液剤を求めて研究を継続する過程におい
て、特定のステビア抽出液と高麗人参と日本薬局方親水
軟膏の組み合わせが、これを引用した場合には優れた健
康増進効果を示すと共に、皮膚に塗布した場合には、ア
トピー性皮膚炎やしもやけ、老人性色素、雀卵症（ソバ
カス）、化粧かぶれによる色素沈着、日光斑、など皮膚
疾患を有効に改善するという知見を得、本発明を完成す
るに至った。即ち、前記先願発明のステビア抽出液を有
効成分とする内服液は優れた作用を与えるものである
が、本発明の液剤は飲用しても塗布しても、各種の疾病
に有効に作用するものであり、この効果は、特定のステ
ビア抽出液に高麗人参を混合し、熟成させ、さらに日本
薬局方親水軟膏に混合攪拌し熟成させることによって、
初めてまろやかな、皮膚用軟膏を得られるものである。The present inventors have further developed an oral liquid using stevia as a raw material,
Although a patent application has been filed as 193301 (hereinafter, sometimes referred to as the prior application invention), a specific stevia extract is required in the process of re-testing the prior application invention and continuing research for a more useful liquid agent. The combination of Ginseng and Hydrophilic Ointment of the Japanese Pharmacopoeia, when cited, shows an excellent health-promoting effect, and when applied to the skin, atopic dermatitis and soybean, senile pigment, sparrow egg The present inventors have found that skin diseases such as skin disease (buckwheat), pigmentation due to makeup rash, and sun spots can be effectively improved, thereby completing the present invention. That is, the oral solution containing the stevia extract of the prior application as an active ingredient gives an excellent action, but the liquid preparation of the present invention effectively acts on various diseases even if it is drunk or applied. This effect is, by mixing ginseng with a specific stevia extract, aging, further mixing and stirring in the Japanese Pharmacopoeia hydrophilic ointment and aging,
For the first time, a mellow, skin ointment can be obtained.
【０００５】そこで本発明の目的は、合成品を含まず、
天然品だけを原料として製造され優れた作用を有する液
剤に日本薬局方親水軟膏と混合攪拌熟成させた軟膏剤お
よびその製造方法を提供することにある。Therefore, an object of the present invention is to exclude a synthetic product,
It is an object of the present invention to provide an ointment prepared by mixing only a natural product as a raw material and having excellent action with a hydrophilic ointment of the Japanese Pharmacopoeia, and agitating and aging the same.
【０００６】[0006]
【課題を解決するための手段】本発明によれば、ステビ
ア植物を原料として、特にその茎部の抽出液を得、濃縮
したものと、高麗人参の抽出液とを有効成分に日本薬局
方親水軟膏と混合攪拌熟成させた軟膏剤が提供される。
さらに、本発明によれば、ステビア植物の成熟した茎部
からの抽出液に高麗人参６年根を混合し、熟成して得ら
れる液剤に日本薬局方親水軟膏と混合攪拌熟成させた軟
膏剤およびその製造方法が提供される。According to the present invention, a stevia plant is used as a raw material, in particular, an extract of the stem is obtained and concentrated, and a ginseng extract is used as an active ingredient in the hydrophilicity of the Japanese Pharmacopoeia. An ointment mixed with an ointment and aged by stirring is provided.
Further, according to the present invention, an extract from a mature stem of a stevia plant is mixed with ginseng 6-year roots, and a liquid preparation obtained by ripening is mixed with a Japanese Pharmacopoeia hydrophilic ointment, and the mixture is aged and aged. A manufacturing method is provided.
【０００７】[0007]
【発明の実施の形態】以下、本発明を具体的に説明す
る。 （ステビア濃縮液の調製）本発明の原料の一つであるス
テビア植物は、南米パラグアイおよびブラジルを原産と
するキク科の多年生植物で、学名をステビア・レバウデ
ィアナ・ベルトニー（Ｓｔｅｖｉａ・Ｒｅｂａｕｄｉａ
ｎａ・Ｂｅｒｔｏｎｉ）といわれるものである。通常、
４月から５月にかけて、株苗あるいは挿し木苗を定植
し、育てるものである。BEST MODE FOR CARRYING OUT THE INVENTION The present invention will be specifically described below. (Preparation of Stevia Concentrate) Stevia plant, which is one of the raw materials of the present invention, is a perennial plant of the family Asteraceae native to Paraguay and Brazil in South America, and has a scientific name of Stevia Rebaudiana Berney (Stevia Rebaudia).
na Bertoni). Normal,
From April to May, seedlings or cuttings are planted and raised.
【０００８】そのステビア植物を十分に成熟させ、１０
月から１１月上旬頃に収穫する。本発明の液剤を製造す
るには、その成熟したステビア植物の茎部分のものを特
に選別し、抽出用の原料とすることが重要である。ステ
ビア植物の茎以外の部分あるいは成熟していないステビ
ア植物を原料とするとして、優れた作用を有する液剤を
製造することはできない。[0008] The stevia plant is fully matured and
It is harvested from the moon to early November. In order to produce the liquid preparation of the present invention, it is important to specifically select the stem portion of the mature stevia plant and use it as a raw material for extraction. It is not possible to produce a liquid preparation having an excellent action by using a part other than the stem of a Stevia plant or an unripe Stevia plant as a raw material.
【０００９】成熟したステビア植物の茎部から収穫した
抽出用原料は、まず乾燥工程にて乾燥することが好まし
い。通常、約７０ないし８０℃で２４時間程度乾燥す
る。次いで、乾燥処理したステビアを１５μ以下、好ま
しくは１ないし８μ程度に粉砕する。[0009] The extraction raw material harvested from the stem of a mature stevia plant is preferably first dried in a drying step. Usually, it is dried at about 70 to 80 ° C. for about 24 hours. Next, the dried stevia is pulverized to 15 μm or less, preferably about 1 to 8 μm.
【００１０】この粉砕物を抽出工程にて抽出処理する。
通常、抽出処理は粉砕物を水に浸し、加熱することによ
り行われる。本発明においては、液剤を製造可能である
範囲において、水に他の溶媒を併用することができる。
抽出温度は、通常水を沸騰させる温度が好適である。ス
テビア原料と水との量の割合は、原料粉末１ｋｇに対し
て水５ないし７リットルがよい。抽出時間は、ステビア
植物の成熟の程度、含水量などにより異なるものである
が、３０分ないし２時間程度が好適である。なお、ステ
ビア原料を１回の抽出処理後に廃棄してもよいが、３回
程度までの抽出処理によっても有効な液剤が得られる。The pulverized material is subjected to an extraction process in an extraction step.
Usually, the extraction treatment is performed by immersing the pulverized material in water and heating. In the present invention, water can be used in combination with another solvent as long as a liquid preparation can be produced.
As the extraction temperature, a temperature at which water is usually boiled is preferable. The ratio of the amount of stevia raw material to water is preferably 5 to 7 liters of water per 1 kg of raw material powder. The extraction time varies depending on the degree of maturation and water content of the Stevia plant, but is preferably about 30 minutes to 2 hours. Although the stevia raw material may be discarded after one extraction process, an effective liquid agent can be obtained by up to three extraction processes.
【００１１】抽出工程にて得られた抽出液を濃縮工程に
て濃縮する。抽出液の濃縮は、釜などの容器に抽出液を
入れ、加熱する方法、あるいは減圧状態にて加熱する方
法などにより行われる。濃縮液の糖度が２０度ないし２
５度になったところで濃縮を中止することが好ましい。[0011] The extract obtained in the extraction step is concentrated in the concentration step. Concentration of the extract is carried out by a method in which the extract is put into a vessel such as a kettle and heated, or a method in which the extract is heated under reduced pressure. The sugar content of the concentrate is 20 degrees to 2
It is preferable to stop the concentration when the temperature reaches 5 degrees.
【００１２】（高麗人参抽出液の調製）本発明のもう一
方の原料である高麗人参は学名をＰａｎａｘ Ｓｃｈｉ
ｎｅｎｇ．Ｎといい、ウコギ科の多年生植物で、肉質
の、直生し分岐した根を有することを特徴とする。古来
からその根は薬として重宝がられているものである。本
発明ではこの高麗人参の根を、特に４年以上の高麗人参
の根を使用することが好適である。高麗人参は、４年未
満のものでは、薬効成分が極めて僅かしか含まれておら
ず、４年根以上になると薬効が著しく優れたものにな
る。とはいっても、６年根以上のものは価格的に極めて
高価であるため経済的に不利であり、４年根ないし６年
根未満のものが好適に使用される。この高麗人参の根を
ステビア抽出液に加え、熟成させることが、本発明にお
いて重要である。この際、高麗人参を適切な大きさに調
整してステビア抽出液に加えることが好ましい。また、
ステビア抽出液として、前記ステビア濃縮液を用いると
特に優れた液剤を得ることができる。(Preparation of Ginseng Extract) Ginseng, which is another raw material of the present invention, has a scientific name of Panax Schi.
neng. N, a perennial plant of the araliaceae family, characterized by having fleshy, straight and branched roots. Since ancient times, its roots have been useful as medicines. In the present invention, it is preferable to use this ginseng root, especially ginseng root of 4 years or more. Ginseng containing less than 4 years contains very little medicinal ingredient, and its medicinal properties are remarkably excellent when the ginseng is more than 4 years old. Nevertheless, those with a root of 6 years or more are economically disadvantageous because they are extremely expensive in terms of price, and those with a root of 4 to less than 6 years are preferably used. It is important in the present invention that the ginseng root is added to the stevia extract and aged. At this time, ginseng is preferably adjusted to an appropriate size and added to the stevia extract. Also,
When the stevia concentrate is used as the stevia extract, a particularly excellent liquid preparation can be obtained.
【００１３】高麗人参の根の使用量は、ステビア抽出液
１０リットルに対して通常、生の場合には、０．５ない
し２ｋｇ、乾燥人参の場合には、１００ｇないし３００
ｇとすることが好ましい。[0013] The amount of ginseng root used is usually 0.5 to 2 kg in the case of raw ginseng and 100 g to 300 g in the case of dry ginseng per 10 liters of stevia extract.
g is preferable.
【００１４】ステビア抽出液と高麗人参との混合液を熟
成する際には、該混合液を、通常、１０ないし３０℃、
好ましくは１０ないし２５℃にて９０ないし７２０日、
好ましくは、１８０ないし３６０日にわたって保持す
る。When the mixture of stevia extract and ginseng is aged, the mixture is usually treated at 10 to 30 ° C.
Preferably at 10 to 25 ° C for 90 to 720 days,
Preferably, it is kept for 180 to 360 days.
【００１５】なお、本発明における熟成とは、前記混合
液を一定条件下にて放置することを意味するものであ
り、その混合液の中に微生物が存在する場合と存在しな
い場合との二つの場合が有り得る。 ステビア植物から酵母菌１）Ｃａｎｄｉｄａ Ｋｒｕｓ
ｅｉおよび２）Ｔｒｉｃｈｏｓｐｏｒｏｎ Ｐｅｎｉｃ
ｉｌｌａｔｕｍが見い出されているので、前記ステビア
抽出液と高麗人参との混合液の熟成工程中において、該
混合液内に酵母菌が存在するとその酵母菌により醗酵さ
れることもありうるのであって、このような場合には、
本発明の熟成はいわゆる醗酵と呼ぶことができる。な
お、熟成工程に入るに先立ち、予め培養した該酵母菌を
濃縮液に加え、次いで熟成工程に入ることもできること
は当然のことである。The term “ripening” in the present invention means that the mixture is left under a certain condition, and there are two cases, that is, the case where microorganisms are present in the mixture and the case where microorganisms are not present. There may be cases. Yeast from Stevia plant 1) Candida Krus
ei and 2) Trichosporon Penic
Since illatum has been found, during the aging step of the mixture of the stevia extract and ginseng, if yeast is present in the mixture, it may be fermented by the yeast, In such a case,
The ripening of the present invention can be called so-called fermentation. Prior to the ripening step, it is a matter of course that the yeast previously cultured can be added to the concentrated solution, and then the ripening step can be started.
【００１６】かくして得られた熟成液を、熟成液原液の
まま、日本薬局方親水軟膏１ｋｇに対して、６０ｃｃ添
加し混合攪拌し１２日間または３０日熟成することによ
って、軟膏剤を製造する。An ointment is produced by adding 60 cc of the ripened liquid thus obtained to a 1 kg hydrophilic ointment of the Japanese Pharmacopoeia as it is, as an undiluted ripened liquid, mixing, stirring and aging for 12 or 30 days.
【００１７】[0017]
【実施例】以下、実施例を挙げて、本発明をより具体的
に説明するが、本発明はこの実施例に限られるものでな
いことはいうまでもない。成熟したステビア植物を１１
月上旬に収穫し、面積６．６ｍ2 のたばこ乾燥機を使用
して、７５±３℃にて２４時間、風量３０ｍ／分で乾燥
した。次にこれを棒で軽くたたいてステビアの茎、葉、
小枝等の夾雑物に分離し、茎のみ集めた。この茎をカッ
ターで３ないし５ｃｍ程度の小片に切断し、次いで粉砕
機（日立製作所製）を用いて粉砕（微粉末）を得た。平
均粒径は、５ミクロンであった。EXAMPLES Hereinafter, the present invention will be described in more detail with reference to Examples, but it goes without saying that the present invention is not limited to these Examples. 11 mature stevia plants
It was harvested at the beginning of the month and dried at 75 ± 3 ° C. for 24 hours at a flow rate of 30 m / min using a tobacco dryer having an area of 6.6 m 2 . Then tap it lightly with a stick and stevia stems, leaves,
It was separated into contaminants such as twigs, and only stems were collected. The stem was cut into small pieces of about 3 to 5 cm with a cutter, and then pulverized (fine powder) using a pulverizer (manufactured by Hitachi, Ltd.). The average particle size was 5 microns.
【００１８】鉄製の釜に６リットルの水を入れて、沸騰
するまで加熱する。一度加熱を中断し、攪拌しながら前
記ステビア茎部の微粉末１ｋｇを静かに投入し、再度沸
騰させ、１時間攪拌しながら加熱する。これを搾り機に
かけ、ステビア液と搾り粕に分離した。かくしてステビ
ア抽出液約４リットルを得た。前記鉄製の釜に４リット
ルの水を入れて、沸騰するまで加熱する。一度加熱を中
断し、前記搾り粕を静かに投入し、再度沸騰させ、１時
間攪拌しながら加熱する。これを搾り機にかけ、ステビ
ア液と搾り粕に分離した。かくしてステビア抽出液約３
リットルを得た。この抽出液と前記抽出液とを合一し、
釜にいれ約４時間加熱沸騰させる。約１リットルの濃縮
液を得た。この濃縮液を濾別後、濾液をステンレススチ
ール製の貯蔵タンクに入れる。Pour 6 liters of water into an iron kettle and heat to boiling. Once the heating is interrupted, 1 kg of the fine powder of the stevia stem is gently charged with stirring, boiled again, and heated with stirring for 1 hour. This was squeezed and separated into stevia liquid and squeezed cake. Thus, about 4 liters of stevia extract was obtained. Add 4 liters of water to the iron kettle and heat to boiling. Once the heating is interrupted, the squeezed cake is gently charged, boiled again, and heated with stirring for 1 hour. This was squeezed and separated into stevia liquid and squeezed cake. Thus stevia extract 3
Liters were obtained. This extract is combined with the extract,
Heat in a kettle and boil for about 4 hours. About 1 liter of concentrate was obtained. After filtering off the concentrate, the filtrate is placed in a stainless steel storage tank.
【００１９】高麗人参６年根を１００ｋｇ加え、２５℃
で３６０日熟成させる。糖度が３１度で甘い芳香を有す
る極めて低い粘度の液体原液が得られる。かくして得ら
れた熟成液に日本薬局方親水軟膏１ｋｇに対して６０ｃ
ｃのステビア濃縮液と高麗人参成分液剤を混合攪拌熟成
させ軟膏剤を製造する事が出来た。Add 100 kg of ginseng 6 years root at 25 ° C
And aged for 360 days. A very low viscosity liquid stock solution with a sugar content of 31 degrees and a sweet aroma is obtained. The ripening solution thus obtained is added to the Japanese Pharmacopoeia hydrophilic ointment at 60 c / kg.
The stevia concentrate of (c) and the ginseng component solution were mixed and aged to produce an ointment.
【００２０】（本発明のステビア濃縮液剤及び皮膚病治
療軟膏剤の使用例）使用が簡単である事や、患者に苦痛
を与えず毎日塗布出来、しかも皮膚に良い影響を与える
と云う効果を得る事が出来た。次の症例に対して治療を
試行した。 １．老人性色素 発部位として、顔面、手背、前腕、伸側部が好発部位で
ある。 ２．雀卵症（ソバカス） 主に顔面に小色斑が斑種状に散在。 ３．化粧かぶれによる色素沈着 ４．日光斑 顔面、頸部に直射日光が当り、発生する発疹。(Examples of Use of Stevia Concentrated Solution and Ointment for the Treatment of Dermatosis of the Present Invention) It is easy to use and can be applied daily without causing any pain to the patient, and has the effect of having a good effect on the skin. Things were done. Treatment was attempted for the following cases: 1. Facial, dorsum of the hand, forearm, and extensor region are the most common senile pigmentation sites. 2. Sparrow egg disease (buckwheat) Small spots are mainly scattered on the face. 3. 3. Pigmentation due to makeup rash Sun spots A rash that occurs when the face and neck are exposed to direct sunlight.
【００２１】[0021]
【発明の効果】本発明の軟膏剤は、ステビア植物の茎部
に存在する薬効成分に加えて高麗人参の有する薬効成分
が相まって、格別に優れた作用をもたらすものである。
すなわち、該液剤を使用すると、生体内にて血行が促進
されるとともに前記薬効成分が微妙な効果を及ぼし、弱
体化した生体を健康な体に戻す作用を有するものと推察
される。本発明の軟膏剤がもたらす効果を次に示す。 適応症状例 やけど、皮膚病、老人性色素、雀卵症（ソバカス）、化
粧かぶれによる色素沈着、日光斑、イボ、ニキビ、等。The ointment of the present invention provides a particularly excellent effect by combining the medicinal components of ginseng in addition to the medicinal components present in the stem of Stevia plant.
In other words, it is presumed that the use of the liquid agent promotes blood circulation in the living body and exerts a delicate effect of the medicinal component, and has an effect of returning a weakened living body to a healthy body. The effects of the ointment of the present invention will be described below. Indication examples: Burns, skin diseases, senile pigments, sphagnum (sobacas), pigmentation due to makeup rash, sun spots, warts, acne, etc.
───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.7 識別記号 ＦＩ テーマコート゛(参考） Ａ６１Ｐ 17/00 Ａ６１Ｐ 17/00 ──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. 7 Identification symbol FI Theme coat ゛ (Reference) A61P 17/00 A61P 17/00
Claims (7)
分とする混合醗酵更に熟成した液剤と、日本薬局方親水
軟膏と混合攪拌熟成軟膏剤。1. A mixed fermentation and an aged liquid preparation containing a stevia stem concentrate and an active ingredient of ginseng, and a mixed ointment mixed with a hydrophilic ointment of Japanese Pharmacopoeia.
の抽出液を濃縮したものである請求項１記載の液剤。2. The liquid preparation according to claim 1, wherein the stevia stem concentrate is a concentrated extract of mature stevia stem.
項１または２記載の液剤。3. The liquid preparation according to claim 1, wherein the ginseng is 4 years old or more.
人参との混合物を熟成させて得られたものである請求項
１ないし３のいずれか１項記載の軟膏剤。4. The ointment according to claim 1, wherein the active ingredient is obtained by aging a mixture of a stevia stem concentrate and ginseng.
とする液剤の製造方法において、ステビア抽出液に高麗
人参を添加混合する工程と、更に、日本薬局方親水軟膏
と該混合物を熟成させる工程を含むことを特徴とする軟
膏剤の製造方法。5. A method for producing a liquid preparation comprising a stevia concentrate and ginseng as active ingredients, a step of adding and mixing ginseng to a stevia extract, and a step of further aging the hydrophilic ointment of the Japanese Pharmacopoeia and the mixture. A method for producing an ointment, comprising:
出液の濃縮液である請求項５記載の軟膏剤の製造方法。6. The method for producing an ointment according to claim 5, wherein the stevia extract is a concentrate of an extract of a mature stevia stem.
で９０日ないし３６０日行われた液剤に日本薬局方親水
軟膏と該混合物を熟成させる請求項５または６記載の軟
膏剤の製造方法。7. The aging step includes the step of heating the mixture to 10 to 25 ° C.
7. The method for producing an ointment according to claim 5, wherein the solution prepared for 90 days to 360 days is aged with a hydrophilic ointment of the Japanese Pharmacopoeia and the mixture.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33440099A JP2001151688A (en) | 1999-11-25 | 1999-11-25 | Stevia concentration solution agent and ointment for treating dermatosis and method for producing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33440099A JP2001151688A (en) | 1999-11-25 | 1999-11-25 | Stevia concentration solution agent and ointment for treating dermatosis and method for producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2001151688A true JP2001151688A (en) | 2001-06-05 |
Family
ID=18276952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP33440099A Pending JP2001151688A (en) | 1999-11-25 | 1999-11-25 | Stevia concentration solution agent and ointment for treating dermatosis and method for producing the same |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2001151688A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003035090A1 (en) * | 2001-10-25 | 2003-05-01 | Kabushiki Kaisha Thieisutebia | Agents relieving anaphylactic allergic reactions and process for producing the same |
| US20120270291A1 (en) * | 2009-03-11 | 2012-10-25 | Jing Cheng | Topical Compositions Comprising Fermented Extracts of Traditional Chinese Medicinal (TCM) Ingredients, and Methods of Making and Using Same |
-
1999
- 1999-11-25 JP JP33440099A patent/JP2001151688A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003035090A1 (en) * | 2001-10-25 | 2003-05-01 | Kabushiki Kaisha Thieisutebia | Agents relieving anaphylactic allergic reactions and process for producing the same |
| US20120270291A1 (en) * | 2009-03-11 | 2012-10-25 | Jing Cheng | Topical Compositions Comprising Fermented Extracts of Traditional Chinese Medicinal (TCM) Ingredients, and Methods of Making and Using Same |
| US8580319B2 (en) | 2009-03-11 | 2013-11-12 | Elc Management, Llc | Topical compositions comprising fermented extracts of traditional chinese medicinal (TCM) ingredients, and methods of making and using same |
| US9233134B2 (en) | 2009-03-11 | 2016-01-12 | El Management Llc | Topical compositions comprising fermented extracts of traditional Chinese medicinal (TCM) ingredients, and methods of making and using same |
| US9327004B2 (en) | 2009-03-11 | 2016-05-03 | Elc Management Llc | Topical compositions comprising fermented extracts of traditional chinese medicinal (TCM) ingredients, and methods of making and using same |
| US9333231B2 (en) | 2009-03-11 | 2016-05-10 | Elc Management Llc | Topical compositions comprising fermented extracts of traditional methods of making and using same |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101817861B1 (en) | Herbal Shampoo Manufacturing Method using Enzyme Extract Fluid of Chinese Medicine and Dendropanax morbifera Lev | |
| KR20100121003A (en) | Soap composition using orient material and manufacturing method thereof | |
| CN104877876A (en) | Mulberry black rice wine and making method thereof | |
| CN110882175A (en) | Extraction method and application of quinoa saponin | |
| CN104688930A (en) | Anti-fatigue ginseng and deer bone health care wine and preparation method thereof | |
| CN107541387A (en) | A kind of Rosa roxburghii fruit wine and production method | |
| KR101560710B1 (en) | Cosmetic compositions for slimming and cellulite reduction containing Chrysanthemum morifolium flower, Coix lacryma-jobi ma-yuen seed, Zingiber officinale root, Schizandra chinensis fruit, Diospyros kaki leaf, Taraxacum officinale, Citrus unshiu peel, Chaenomeles sinensis fruit, Zizyphus jujuba fruit, Cornus officinalis fruit complex extract | |
| KR20030069500A (en) | The preparation of fermentation Fig-vinegar using korean drug agent and fig fruit | |
| KR102301069B1 (en) | Collagen jujube juice and manufacturing method of the same | |
| KR20200019303A (en) | Wood cultivated ginseng Matured solution and manufacturing method | |
| CN107348052A (en) | A kind of passion fruit tea beverage preparation technology | |
| KR20150061839A (en) | Manufacturing method of composition of enzyme for preventing lose of hair and Composition of enzyme for preventing lose of hair manufactured by the same | |
| JP2001151688A (en) | Stevia concentration solution agent and ointment for treating dermatosis and method for producing the same | |
| JP2001192342A (en) | Method for producing mixture of liquid formulation of concentrated stevia with ripe punica granatum | |
| KR100351750B1 (en) | A Preparing Method for Ginseng Green Tea from Ginseng Leafs | |
| CN109294852A (en) | A kind of tealeaves dinner party with singsong girls in attendance and preparation method thereof | |
| CN104921135B (en) | A kind of health products and preparation method thereof | |
| CN109198109A (en) | A kind of fig tea and preparation method thereof | |
| KR102261238B1 (en) | Functional tea drink having snail mucus and medical herb and manufacturing method thereof | |
| KR102603164B1 (en) | Cream honey and manufacturing method of the same | |
| KR102444816B1 (en) | Preparing method of the functional rice paste using mulberry leaves, mulberry and glutinous rice | |
| CN106692021A (en) | Tea cake hair-care composition and preparation method thereof | |
| JPH0683656B2 (en) | Method for producing ginseng cream | |
| JP3195444B2 (en) | Health drink and method for producing the same | |
| JPH054928A (en) | Ginseng leaf extract composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20051011 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20060221 |