JP2001048743A - Skin lotion - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a skin lotion excellent in preservation stability, especially stability at a low temperature. SOLUTION: This skin lotion contains a lysophospholipid and a fatty acid ester of sucrose, and >=80 wt.% of the fatty acid ester of the sucrose is a monoester. The fatty acid ester of the sucrose is the one obtained by forming an ester bond between one or more hydroxy groups in the sucrose and a saturated or unsaturated fatty acid, and the constituent fatty acid is the one having about 10-24 carbons, concretely, e.g. lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid and behenic acid. The lysophospholipid is any one of monoacyl type phospholipids, e.g. lysophosphatidylcholine, lysophosphatidylethanolamine, lysophosphatidylinositol, lysophosphatidic acid and lysophosphatidylserine, and a mixture thereof can be also used.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

[0001] The present invention relates to a lotion having excellent storage stability.

[0002]

BACKGROUND ART lysophospholipid selected egg yolk, soybeans, an acyl group of phospholipids present in animal and plant cells and the like were treated with phospholipase A _2, which is a kind of phospholipid degrading enzyme, located in the 1-position or 2-position Is hydrolyzed to a hydroxyl group. Since lysophospholipids have a hydroxyl group in the molecule and thus have enhanced hydrophilicity, lysophospholipids have an excellent emulsifying effect and a further solubilizing effect, and in recent years, naturally-derived surfactants have been used in various fields. It came to be used as.
Similarly, in the cosmetics field, lysophospholipids, which are naturally-derived surfactants, have been attracting attention due to their safety and natural taste, and their use as emulsifiers and solubilizers. It has also been used as a humectant because of having the same.

However, cosmetics using lysophospholipids,
In particular, there is a problem that, when the lotion is stored at a low temperature in a lotion in which the appearance change is easily recognized, a precipitate or a smudge is generated, the viscosity is increased, and the commercial value is impaired. In order to solve such a problem, there has been proposed a lotion in which storage stability at low temperature is improved by adding saponin (Japanese Patent Application Laid-Open No. 2-169507). However, it is still difficult to say that it has a satisfactory degree of stability, and further improvement is desired.

[0004]

SUMMARY OF THE INVENTION An object of the present invention is to provide a lotion having excellent storage stability, especially at low temperatures.

[0005]

Means for Solving the Problems The inventors of the present invention have conducted intensive studies to achieve the above object, and as a result, surprisingly, the sucrose fatty acid ester, which is a monoester, is contained in an amount of about 80% by weight or more. It was also found that even when stored at a low temperature, it was difficult to cause generation of precipitates and dust, or increase in viscosity, and the present invention was completed. That is, the present invention provides a lotion containing a lysophospholipid and a sucrose fatty acid ester, wherein about 80% by weight or more of the sucrose fatty acid ester is a monoester.
It is to provide.

[0006]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below. In the present invention, the “lotion” may be any water-based cosmetic having a transmittance at a wavelength of 660 nm of 80% or more and is generally a lotion. In the present invention, various extracts, humectants such as hyaluronic acid, and serums containing relatively high concentrations of physiologically active substances such as whitening agents such as ascorbic acid phosphate are also included. . Further, the lotion of the present invention may be used not only on the skin but also on the scalp or hair.

The sucrose fatty acid ester contained in the present invention is a sucrose having one or more hydroxyl groups and a saturated or unsaturated fatty acid in an ester bond. Usually 10 carbon atoms
Up to about 24, specifically, for example, lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, behenic acid and the like are used.
Generally, commercially available sucrose fatty acid esters are a mixture of a monoester in which one hydroxyl group and a fatty acid in sucrose are ester-bonded, a diester in which two ester bonds are bonded, and a triester in which three ester bonds are bonded. About 80% by weight or more of the sucrose fatty acid ester used in the present invention is a monoester. If the content of the monoester is lower than 80% by weight as shown in the test examples described later, a lotion having excellent storage stability at low temperatures cannot be obtained, which is not preferable. The content of the sucrose fatty acid ester is at least 1 part by weight, preferably 5 parts by weight or more based on 50 parts by weight of the lysophospholipid, and the upper limit is not economical because no further effect can be expected. It is desirable that the amount of the sucrose fatty acid ester be 100 parts by weight or less based on 1 part by weight of the lysophospholipid.

The lysophospholipid contained in the present invention comprises:
Any monoacyl type phospholipid may be used, and examples thereof include lysophosphatidylcholine, lysophosphatidylethanolamine, lysophosphatidylinositol, lysophosphatidic acid, and lysophosphatidylserine, and a mixture thereof. Moreover, lysophospholipids, for example, egg yolk, soybeans, obtained by the phospholipids present in animal and plant cells and the like are treated with phospholipase A _2, which is a kind of phospholipid degrading enzyme. In particular, lysophosphatidylcholine derived from egg yolk is preferable as a raw material for lotion because it has excellent oxidative stability because the acyl group is almost entirely composed of saturated fatty acids, and is easily transparently dissolved in water. The content of the lysophospholipid is not particularly limited, but may be 0.0001 to the total lotion.
It is good to make it contain -5.0 weight%.

The production of the lotion of the present invention is not particularly limited, but is generally used as a raw material of the lotion, for example, a humectant such as hyaluronic acid, collagen, polyhydric alcohol, animals and plants, or Synthetic oils and fats, various extractants such as elastin, whitening agents such as ascorbic acid phosphate, fragrances, preservatives, coloring agents, alcohols, surfactants and the like are appropriately selected within a range that does not impair the effects of the present invention. By dissolving or dispersing these raw materials, lysophospholipid and sucrose fatty acid ester in purified water, the lotion of the present invention can be obtained. In addition, since lysophospholipids and sucrose fatty acid esters are heated and purified water, or after being dispersed, they are easily transparently dissolved by heating,
It is preferable to produce a lotion by such a method.

Next, the present invention will be described in more detail based on examples and test examples.

[0011]

Example 1 Example 1 <Prescription>-Egg yolk lysophosphatidylcholine (manufactured by Kewpie Co., Ltd., trade name "Egg yolk lecithin LC-100") 1.0% by weight-Sucrose laurate ester (manufactured by Mitsubishi Chemical Foods Corporation) , Brand name "Ryoto Sugar Ester L-1695 (monoester: about 80% by weight)") 1.0% by weight ・ Sodium hyaluronate aqueous solution (1% by weight) (Kewpie Co., Ltd., brand name "Hyaluron Sun HA-Q1" 1.0% by weight-Glycerin 5.0% by weight-Methylparaben 0.1% by weight-Purified water 91.9% by weight <Production method> After heating purified water to 70 ° C, egg yolk lysophosphatidylcholine, sucrose fatty acid The ester, glycerin and methyl paraben were dissolved. After the solution was cooled to room temperature, an aqueous solution of sodium hyaluronate was added to make the solution uniform, and a clear lotion was obtained. Even when the obtained lotion was stored at 4 ° C. for one month, the lotion was stable without generation of precipitates and mist, and no change in viscosity.

Example 2 <Formulation> Egg yolk lysophosphatidylcholine (manufactured by Kewpie Co., Ltd., trade name “yolk lecithin LC-100”) 1.0% by weight ・ Sucrose laurate ester (manufactured by Mitsubishi Chemical Foods Corporation) Trade name "Ryoto Sugar Ester L-1695 (monoester: about 80% by weight)") 0.2% by weight ・ POE (60) hydrogenated castor oil 0.1% by weight ・ α-tocopherol 0.05% by weight ・ Soluble Eggshell membrane (manufactured by KUP Co., Ltd., trade name "EM Protein-P") 0.05% by weight ・ Dipropylene glycol 10.0% by weight ・ Methylparaben 0.1% by weight ・ Purified water 88.5% by weight <Production method Sucrose fatty acid ester and methyl paraben were dissolved in purified water heated to> 70 ° C. On the other hand, 70 ° C
The yolk phosphatidylcholine, POE (60) hydrogenated castor oil and α-tocopherol were uniformly dispersed in the heated dipropylene glycol, and the aqueous solution was poured while stirring this dispersion to make it uniform. Next, the soluble eggshell membrane was dissolved and cooled to room temperature to obtain a clear lotion. Even when the obtained lotion was stored at 4 ° C. for one month, the lotion was stable without generation of precipitates and mist, and no change in viscosity.

[0013]

Test Example A lotion containing a stabilizer shown in Table 1 was produced according to the following formulation and production method. The obtained lotion was stored at 4 ° C. for one month, and after the storage, the presence or absence of a precipitate or a stain was observed, and the change in viscosity was observed.
In addition, all the samples were transparent solutions having almost no viscosity before storage. <Prescription>-Lysophospholipid (QP Corporation, trade name "Egg Yolk Lecithin LC-100") 1.0% by weight-Stabilizer 1.0% by weight-Methylparaben 0.1% by weight-Purified water 97.9 % By weight <Production method> After heating purified water to 70 ° C, lysophospholipid,
The stabilizer and methyl paraben were dissolved to obtain a lotion. The obtained lotion was filled into a screw-mouth bottle and allowed to stand in a low-temperature room at 4 ° C.

[0014]

[Table 1]

The symbols for overall evaluation in the table are as follows. ：: No precipitate and no smear were generated, and almost no change in viscosity was observed. ：: Although the viscosity was slightly increased, no precipitate and no smell were generated. Δ: Smearing and slight increase in viscosity were observed, but no precipitate was generated. ×: A precipitate was generated.

From Table 1, it is understood that a lotion having excellent stability at low temperature can be obtained by adding a sucrose fatty acid ester containing 80% by weight or more of a monoester to a lotion containing lysophospholipid. Is done.

As described above, the lotion of the present invention has excellent stability at low temperatures, and therefore has a favorable quality as a cosmetic and is expected to further expand demand.

Claims (1)

[Claims] 1. A lotion containing a lysophospholipid and a sucrose fatty acid ester, wherein about 80% by weight or more of the sucrose fatty acid ester is a monoester.