JP2001019994A - Soapwort (saponaria officinalis) essence-formulated detergent - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a detergent that has high detergency as well as excellent humectancy and can prevent skin from being roughened, even when it is continuously used for a long period of time. SOLUTION: The detergent prepared by formulating soapwort (Saponaria officinalis) essence to a mixture of surfactants, antimicrobial agent and the like can give the skin moist feeling without skin roughening, as its detergency and microbicidal action are retained.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to a cleaning agent having an excellent moisturizing effect.

[0002]

2. Description of the Related Art Conventional cleaning agents contain a large amount of a surfactant as a cleaning component. When the cleaning agent comes into direct contact with the skin, sebum on the skin surface is removed by the surfactant.
As a result, the sebum film, which is a protective film on the surface of the skin, is destroyed, and NMF (Natural Moisture Facto) in the stratum corneum is destroyed.
r) and the loss of stratum corneum lipids,
The skin surface lubrication function and the stratum corneum moisture retention function decrease. Therefore, the water content of the stratum corneum decreases, the moist feeling of the skin is lost, and the surface of the finger becomes rough. Therefore, development of a detergent that prevents roughening of the hand skin and has high detergency has been desired.

[0003] On the other hand, it is often thought that bacteria on the epidermis surface are killed by washing the skin, or are washed away from the skin and disappear, but in reality, wrinkles on the skin surface, Bacteria that have accumulated on the surface of the wound, such as a wound, will not be removed by ordinary washing. For this reason, cleaning agents containing an antibacterial agent in addition to a surfactant are commercially available depending on the purpose of cleaning. In particular, bacteria easily propagate on contact lenses, especially soft contact lenses, and the propagated bacteria cause corneal epithelial damage and eye inflammation. Therefore, before handling these lenses, it is desirable to perform not only hand washing but also sterilization. However, antimicrobial agents generally show skin damage at high concentrations, and even at low concentrations, continuous use can destroy the sebum membrane and elute keratinocyte lipids.
Decreases skin barrier function. As a result, the stratum corneum moisture retention function is reduced, and the moist feeling of the skin is lost. The use of antimicrobial agents not only results in a worsened finger feel, but can even result in damage to the contact lens by handling the contact lens with rough hands.

[0004] Glycerin, propylene alcohol, sorbitol, urea, and the like have been blended in many of the conventional cosmetics and cleaning agents, but all of them are not necessarily in terms of detergency, moisturizing property, and feeling of use. It was not satisfactory. For this reason, there has been a demand for the development of a cleaning agent that sufficiently removes dirt from fingers and has excellent feeling on use without rough skin.

[0005] By the way, an extract of Soapwort, a kind of plant, is known to have an astringent effect, a diuretic effect, a liver disease, and an antitussive expectorant, and its rhizome contains a large amount of saponin and has been used as a soap. Japanese Patent Application Laid-Open No. 9-20619 discloses a cosmetic cleansing composition containing squalene as an oil and fat component, an extract of baldan (salted burdock), salvia, lemon, watercress, and vegetation, and an extract of saponosa. However, there is no disclosure about the combination of an antibacterial agent having a moisturizing effect and a bactericidal effect by Soapwort. That is, there has been no report on enhancing the moisturizing effect by adding Soapwort extract to a detergent containing a surfactant or an antibacterial agent.

[0006]

DISCLOSURE OF THE INVENTION The present invention has been made in view of the above circumstances, and has as its object to provide a high detergency, excellent moisture retention, and a surfactant even when used continuously. It is an object of the present invention to provide a cleaning agent capable of preventing rough skin due to the above. The present invention, in a preferred embodiment thereof, provides a cleaning agent having further excellent bactericidal activity. In another preferred embodiment, the present invention also provides a cleaning agent for cleaning a finger before handling a contact lens, and a method for cleaning a finger using the cleaning agent.

[0007]

Means for Solving the Problems The present inventors have conducted intensive studies in order to solve the above-mentioned problems, and as a result, a detergent containing a soap plant extract in addition to a surfactant, an antibacterial agent, and the like has been developed. The inventors have found that even after continuous use, the skin has no roughening and can give a moist feeling to the skin while maintaining the detergency and the sterilizing power, and have completed the invention.

[0008] That is, the present invention relates to a novel cleaning agent having an enhanced moisturizing effect on the skin by incorporating a soap plant extract, and more specifically, (1) characterized by containing a soap plant extract and a surfactant. And cleaning fee,
(2) containing a soap plant extract as a moisturizing component,
(3) The cleaning agent according to (1) or (2), which contains 0.001 to 20% by weight of the soap plant extract (3). .0
(1) The cleaning agent according to any one of (1) to (3), which further contains an antibacterial agent, the cleaning agent according to any one of (1) to (4). Cleaning fee,
(6) The cleaning agent according to (5), which contains an antibacterial agent in a range of 0.001 to 10% by weight, (7) for cleaning a finger before handling a contact lens, (1) to (6).
(8) The cleaning fee according to any one of (1) to (6).
A method for cleaning a finger before handling a contact lens, using the cleaning agent according to any one of the above.

[0009]

BEST MODE FOR CARRYING OUT THE INVENTION The cleaning agent of the present invention is characterized by containing a soap plant extract and a surfactant.

The Soapwort extract used in the present invention comprises:
The rhizome of Soapwort can be powdered and prepared using water or an extraction solvent such as ethanol, ether, polyhydric alcohol, or squalane. In the present invention, particularly, ethanol, 1,3-butylene glycol, propylene glycol, or an aqueous solution containing these, or those extracted with squalane are preferable. Soapwort extract contains flavonoids and saponins,
As the Soapwort extract used in the present invention, those which can confirm the content of these components when a confirmation test is carried out in accordance with the "Cosmetic Component Standards". The amount of the Soapwort extract to be added to the cleaning agent of the present invention is such that the washing agent is not colored over time (the Soapwort extract is a pale green brown to brown liquid) and a moisturizing effect is also recognized. Preferably it is 0.001 to 20% by weight, more preferably 0.01 to 10% by weight.

The surfactant used in the present invention is not particularly limited as long as it can be used in the field of cosmetics and the like, and any surfactant having a different hydrophilic group or structure can be used. Examples of the anionic surfactant include, for example, soap base, fatty acid soaps such as sodium laurate, sodium palmitate, and coconut oil fatty acid potassium, alkyl ether carboxylate, fatty acid amide ether carboxylate, acyl lactate, N- Acyl glutamate, N-acyl alanine salt, N-acyl-ω-amino acid salt, alkane sulfonate, α-olefin sulfonate, α-sulfofatty acid methyl ester salt, acyl isethionate salt, alkyl glycidyl ether sulfonate, Monolauroyl monoethanolamide sodium polyoxyethylene sulfosuccinate, sodium lauryl polypropylene glycol sulfosuccinate, sodium di-2-ethylhexyl sulfosuccinate, lauryl dinatri POE sulfosuccinate Alkylsulfosuccinate, alkylsulfoacetate, alkylbenzenesulfonate, alkylnaphthalenesulfonate, N-acylmethyltaurine, formalin condensation sulfonate, alkyl sulfate, alkyl ether sulfate, alkylaryl ether Sulfate, fatty acid alkanolamide sulfate, fatty acid monoglyceride sulfate, alkyl phosphate, polyoxyethylene alkyl ether phosphate, alkylaryl ether phosphate, fatty acid amide ether phosphate, and the like.

Examples of the cationic surfactant include a cyclic quaternary ammonium salt, a fatty acid amidoamine salt,
Examples thereof include quaternary ammonium salts, alkyltrialkylene glycol ammonium salts, and alkyl ether ammonium salts.

The amphoteric surfactants include, for example, betaine type such as 2-heptadecyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, amide laurate betaine, betaine lauryldimethylaminoacetate, glycine type, amino acid and the like. Carboxylates such as propionic acid type, sulfonic acid type, sulfuric acid type and phosphoric acid type are exemplified.

Examples of the nonionic surfactant include propylene glycol monofatty acid esters such as propylene glycol monostearate, ethylene glycol monofatty acid esters, glycerin monocottonseed oil, glycerin monoerucate, glycerin sesquioleate, and glycerin monostearate. Fatty acid esters of polyhydric alcohols, such as glycerin polyglycerin fatty acid esters such as glycerin monostearate malic acid, polyglycerin fatty acid esters, sorbitan fatty acid esters, sucrose fatty acid esters, methyl glucoside fatty acid esters, and alkyl polyglucosides; Alkyl ether, POE alkyl ether, POE alkyl phenyl ether, POE phytosterol, POE cholestanol, PO POE ethers, such as port shea oxy polo pyrene alkyl ethers, POE fatty acid monoesters, POE glycol fatty acid esters, polyoxyethylene glycerin fatty acid ester, POE sorbitan fatty acid esters, POE sorbitol fatty acid ester, P
Examples include OE methyl glucoside fatty acid ester, POE castor oil, POE hardened castor oil, POE animal and vegetable oils, POE alkyl ether fatty acid esters, and ether esters such as POE polyoxypropylene glycol.

Other surfactants include POE alkylamines, POE fatty acid amides, alkyldiethanolamides, alkylamioxides, POE alkyl mercaptans, fluorine surfactants, silicone surfactants, polypeptide derivatives, natural surfactants Agents and the like.

The Soapwort extract also has a surface active effect because it contains saponin which is a natural surfactant. However, since a sufficient washing effect cannot be expected by itself, the detergent of the present invention contains a surfactant other than Soapwort extract. Is blended in one or more types. Of these, polyoxyethylene sulfosuccinate disodium lauryl sulfate, lauryl sulfate amidopropyl betaine solution, and coconut oil fatty acid potassium solution are particularly preferred. One or more of these surfactants may be used. The amount of surfactant incorporated into the cleaning agent is
It does not cause skin damage, foams, has good cleaning properties,
In addition, from the viewpoint that a high moisturizing effect and a high cleaning effect can be obtained when used in combination with the above Soapwort extract, it is preferably 3.0 to 90% by weight, more preferably 10 to 70% by weight. It is.

The detergent of the present invention can further contain an antibacterial agent. Examples of the antibacterial agent used include, but are not limited to, berberine chloride, benzalkonium chloride, benzethonium chloride, chlorhexidine chloride, triclosan, isopropylmethylphenol triclosan, trichlorocarbanilide, sodium bisulfite, and 2-alkyl-N- Carboxymethyl-N-hydroxyethylimidazolium betaine, benzoic acid, aluminum benzoate, sodium benzoate, isopropanol, zinc undecylenate, undecylenic acid monoethanolamide, ethanol, alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, stearyldimethylbenzyl chloride Ammonium, stearoylcholaminoformylmethylpyridinium chloride, cetylpyridinium chloride, lysozyme chloride, Acid alkyldiaminoethylglycine solution, ortho-phenylphenol, ortho-phenylphenol, sodium, No. 101 photosensitizer,
Photosensitive element 201, Photosensitive element 301, Photosensitive element 401, Chlorhexidine gluconate solution, Cresol, Chloramine T, Chlorxylenol, Chlorcresol, Chlorphenesin, Chlorobutanol, Salicylic acid, Sodium salicylate, Dipropylene glycol, Albromide Kisisoquinonium, cetyltrimethylammonium bromide, domiphen bromide, sorbic acid, potassium sorbate, zeolite compounds, thiantol, thymol, dehydroacetic acid, sodium dehydroacetate, paraoxybenzoate, parachlorophenol, paraphenol zinc zinc sulfonate , Halocarban, 4-hydroxy-2-oxobenzoxathiol, hinokitiol, zinc pyrithione,
Phenylethyl alcohol, phenoxyethanol, phenol, phenoxyisopropanol, 1,3-butylene glycol, propionic acid, sodium propionate, potassium propionate, propylene glycol, hexachlorophen, hexylene glycol, benzyl alcohol, 1,2-pentanediol, methyl Antimicrobial agents such as chloroisothiazolinone / methylisothiazolinone solution, sodium lauryldiaminoethylglycine solution, betaine lauryldimethylaminoacetate, sodium lauroyl sarcosine, and resorcinol. Among these, benzalkonium chloride, benzethonium chloride, propylene glycol, resorcinol, phenoxyethanol,
Zeolite compounds, triclosan, triclocarbanilide and isopropylmethylphenol are particularly preferred. One or more of these antibacterial agents may be used. The amount of the antibacterial agent to be added to the cleaning agent is preferably 0.0
0.01 to 10% by weight, more preferably 0.01 to 5% by weight.
% By weight.

The cleaning agent of the present invention is generally used in cosmetics as required within a quantitative and qualitative range that does not impair the quality of appearance stability and viscosity, and does not impair the effect of the present invention. Active ingredients, thickeners, colorants, dispersants, humectants, preservatives, fragrances, and the like. The pH of the cleaning agent of the present invention is preferably adjusted to 4.5 to 9.5.

The cleaning agent of the present invention is not limited to these, but includes, for example, liquids, foams, gels, creams,
Shapes and dosage forms such as pastes, powders, and solid preparations are conceivable. In particular, detergents in liquid or gel form are preferred. The cleaning agent of the present invention can be produced by the same method as a general cleaning agent.

Since the detergent of the present invention contains a soap plant extract in addition to a surfactant, the moisturizing property to the skin is not impaired, and the rough skin can be prevented. Further, the same effect can be exerted when an antibacterial agent is added. For this reason, for example, at the time of washing for removing dirt derived from skin metabolites such as sweat and aged horns on the skin surface, microorganisms, and dirt from the outside such as dust, it is easy to adsorb dirt such as proteins and lipids. It can be suitably used for washing a finger before handling a contact lens, particularly a soft contact lens, and for washing dishes and the like.

[0021]

EXAMPLES The present invention will be described below in more detail with reference to examples, but the present invention is not limited to these examples. In addition, face wash, body and hair cleansing agents were prepared according to the compositions of Examples 1 to 3 below, and finger cleansing agents were prepared according to the compositions of Examples 4 to 13 and Comparative Examples 1 and 2. Each component was heated and dissolved as needed, mixed and stirred, and then cooled to obtain a good cleaning agent. The compounding amount is% by weight. (1) Examples and Comparative Examples [Example 1] Cleansing agent for facial cleansing

[Table 1]

Example 2 Body Wash

[Table 2]

Example 3 Hair Washing Material

[Table 3]

[Examples 4 to 11] Finger wash

[Table 4]

[Examples 12 and 13, Comparative Examples 1 and 2] Finger wash

[Table 5]

(2) Evaluation method of moisturizing effect The moisturizing effect was evaluated according to the following evaluation criteria. Using each sample, have a specialized panel (five women, five men) wash their fingers twice a day for 7 days, and analyze the skin after use (dryness, smoothness). The moisturizing effect was evaluated. The panel was given the following evaluation score by questionnaire, and the average value was used as an index.

[Table 6]

(3) Evaluation method of cleaning effect Using each sample, a specialized panel (five women and five men) was used to clean the fingers, and after the cleaning, the condition of removing the stains on the fingers and the fingers. Was evaluated for its bactericidal effect. The cleaning effect was evaluated by visually observing the condition before and after cleaning of the hand to which the cosmetic was previously attached, using the cosmetic stain which might adhere to the contact as an index. For testing, 1 g of detergent
Was used for 2 minutes, followed by washing with water. The degree of hand washing was evaluated according to the following evaluation criteria. Evaluation criteria Evaluation of cleaning effect A: Eight or more out of ten answered that they were good. ：: 5 to 7 out of 10 respondents answered that they were good. B: 2 to 4 out of 10 respondents answered that they were good. ×: Less than 2 out of 10 responded as good. (4) Evaluation method of bactericidal effect Using each sample, a specialized panel (five women and five men) was used to wash the fingers, and the bactericidal effect of the fingers was evaluated. Using the agar stamp method, the number of bacteria before and after washing was measured and evaluated. In the test, washing was performed for 2 minutes using 1 g of a detergent, and then washing with water was performed. According to the following evaluation criteria,
The degree of hand washing and the bactericidal activity were evaluated. Evaluation criteria Evaluation of bactericidal effect A: The number of bacteria was significantly reduced before and after washing. ：: The number of bacteria slightly decreased before and after washing. Δ: The number of bacteria slightly decreased before and after washing. ×: The number of bacteria hardly decreased before and after washing. (5) Evaluation Results of Each Effect Using Examples 1 to 13 and Comparative Examples 1 and 2, the results of evaluating the moisturizing effect according to the above evaluation criteria were obtained.
In the average evaluation of 13 samples, none of the panels caused rough skin, and after use, there was no dry feeling, a moist feeling and a smooth feeling were felt, and the moisturizing effect of the Soapwort extract was recognized. On the other hand, in Comparative Examples 1 and 2, the panel felt average dryness of fingers after use and was rough.
Some of the results are shown in Table 7. In addition, using the samples of Examples 12 and 13 and Comparative Examples 1 and 2, the degree of cleansing of the fingers and the sterilizing power were evaluated. In Examples 12 and 13 in which the soap plant extract was blended, the evaluation was that the bactericidal effect was almost the same and the washing effect was slightly increased, but in Comparative Examples 1 and 2, the moisturizing effect was hardly observed. The results are shown in Table 7.

[Table 7]

[0028]

EFFECTS OF THE INVENTION The detergent of the present invention can prevent skin roughness due to a surfactant or an antibacterial agent even after continuous use, and is extremely excellent in moisturizing properties, even after continuous use by blending with soap soap extract. For this reason, the cleaning agent of the present invention can be suitably used, for example, as a cleaning agent for fingers before wearing a contact lens, as a cleaning agent for dishes, a cleaning agent for face washing, a cleaning agent for body, and a cleaning agent for hair. .

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI Theme coat ゛ (Reference) A61K 31/085 A61K 31/085 31/14 31/14 31/235 31/235 A61P 17/00 101 A61P 17 / 00 101 17/16 17/16 B08B 3/08 B08B 3/08 Z C11D 3/48 C11D 3/48 F term (reference) 3B201 AA46 AB51 BB01 BB92 BB94 4C083 AA111 AA112 AB332 AC122 AC132 AC172 AC242 AC302 AC472 AC482 AC562 AC642 AC662 AC782 AC812 AC902 AD132 AD262 BB01 BB48 CC23 CC38 EE03 EE12 4C206 AA02 CA17 CA18 CA27 DB17 DB43 FA42 MA03 MA05 MA83 ZA90 ZB35 4H003 AB09 AB10 BA09 BA12 BA15 DA02 DA16 EB04 EB07 EB09 EB43 ED02 FA21 FA01 FA21

Claims (8)

[Claims] 1. A cleaning agent comprising a soap plant extract and a surfactant. 2. The cleaning agent according to claim 1, which contains a soap plant extract as a moisturizing component. 3. The cleaning agent according to claim 1, which contains the Soapwort extract in the range of 0.001 to 20% by weight. 4. The cleaning agent according to claim 1, which contains a surfactant in a range of 3.0 to 90% by weight. 5. The cleaning agent according to claim 1, further comprising an antibacterial agent. 6. The cleaning agent according to claim 5, comprising an antibacterial agent in a range of 0.001 to 10% by weight. 7. The cleaning agent according to claim 1, which is used for cleaning fingers before handling a contact lens. 8. A method for cleaning a finger before handling a contact lens, using the cleaning agent according to claim 1.