JP2001002592A5 - - Google Patents
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- Publication number
- JP2001002592A5 JP2001002592A5 JP1999172176A JP17217699A JP2001002592A5 JP 2001002592 A5 JP2001002592 A5 JP 2001002592A5 JP 1999172176 A JP1999172176 A JP 1999172176A JP 17217699 A JP17217699 A JP 17217699A JP 2001002592 A5 JP2001002592 A5 JP 2001002592A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- gene
- composition
- phospharidylcholine
- phosphatidylethanolamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 description 12
- 108090000623 proteins and genes Proteins 0.000 description 7
- 150000003904 phospholipids Chemical class 0.000 description 3
- JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 description 2
- 102000007327 Protamines Human genes 0.000 description 2
- 108010007568 Protamines Proteins 0.000 description 2
- 102000004338 Transferrin Human genes 0.000 description 2
- 108090000901 Transferrin Proteins 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 150000008104 phosphatidylethanolamines Chemical class 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000012581 transferrin Substances 0.000 description 2
- PORPENFLTBBHSG-MGBGTMOVSA-N 1,2-dihexadecanoyl-sn-glycerol-3-phosphate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=O)OC(=O)CCCCCCCCCCCCCCC PORPENFLTBBHSG-MGBGTMOVSA-N 0.000 description 1
- TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 description 1
- ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 description 1
- ATBOMIWRCZXYSZ-XZBBILGWSA-N [1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] (9e,12e)-octadeca-9,12-dienoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCC(O)CO)OC(=O)CCCCCCC\C=C\C\C=C\CCCCC ATBOMIWRCZXYSZ-XZBBILGWSA-N 0.000 description 1
- AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- ZGSPNIOCEDOHGS-UHFFFAOYSA-L disodium [3-[2,3-di(octadeca-9,12-dienoyloxy)propoxy-oxidophosphoryl]oxy-2-hydroxypropyl] 2,3-di(octadeca-9,12-dienoyloxy)propyl phosphate Chemical compound [Na+].[Na+].CCCCCC=CCC=CCCCCCCCC(=O)OCC(OC(=O)CCCCCCCC=CCC=CCCCCC)COP([O-])(=O)OCC(O)COP([O-])(=O)OCC(OC(=O)CCCCCCCC=CCC=CCCCCC)COC(=O)CCCCCCCC=CCC=CCCCCC ZGSPNIOCEDOHGS-UHFFFAOYSA-L 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- -1 phospharidylcholine Natural products 0.000 description 1
- 150000003905 phosphatidylinositols Chemical class 0.000 description 1
- 229940048914 protamine Drugs 0.000 description 1
- 229950008679 protamine sulfate Drugs 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11172176A JP2001002592A (ja) | 1999-06-18 | 1999-06-18 | 遺伝子導入用組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11172176A JP2001002592A (ja) | 1999-06-18 | 1999-06-18 | 遺伝子導入用組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001002592A JP2001002592A (ja) | 2001-01-09 |
| JP2001002592A5 true JP2001002592A5 (enExample) | 2006-06-29 |
Family
ID=15936994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11172176A Pending JP2001002592A (ja) | 1999-06-18 | 1999-06-18 | 遺伝子導入用組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2001002592A (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4987474B2 (ja) * | 2003-06-04 | 2012-07-25 | ジョージタウン・ユニバーシティ | リポソーム複合体の安定性および使用期限を改良するための方法 |
| JP2006248978A (ja) | 2005-03-10 | 2006-09-21 | Mebiopharm Co Ltd | 新規なリポソーム製剤 |
| JP5030533B2 (ja) * | 2006-11-01 | 2012-09-19 | 株式会社ナリス化粧品 | 美白用皮膚組成物 |
| JP2008115101A (ja) * | 2006-11-02 | 2008-05-22 | Naris Cosmetics Co Ltd | 美白用皮膚組成物 |
| EP2123256A1 (en) | 2008-05-19 | 2009-11-25 | Ruhr-Universität Bochum | Perfluorcarbon nanoemulsions with endocytosis enhancing surface for gene-transfer |
| KR101229809B1 (ko) | 2010-04-14 | 2013-02-05 | 광주과학기술원 | 유전자 운반체 |
| WO2011132939A2 (ko) * | 2010-04-20 | 2011-10-27 | 광주과학기술원 | Rtk에 특이적으로 결합하는 rtk-bpb |
| KR20130103299A (ko) * | 2010-04-20 | 2013-09-23 | 광주과학기술원 | Ｒｔｋ에 특이적으로 결합하는 ｒｔｋ―ｂｐｂ |
| CA2857604A1 (en) | 2011-12-22 | 2013-06-27 | Nuvo Research Gmbh | Liposomal chlorite or chlorate compositions |
| CN105521497B (zh) * | 2015-12-30 | 2019-01-04 | 大连民族大学 | 蔗糖脂肪酸酯嵌入式阳离子脂质体基因载体系统及其制备方法和应用 |
| US11339209B2 (en) | 2016-11-14 | 2022-05-24 | Novartis Ag | Compositions, methods, and therapeutic uses related to fusogenic protein minion |
| JP2023513132A (ja) * | 2020-02-05 | 2023-03-30 | コリア アドバンスド インスティチュート オブ サイエンス アンド テクノロジィ | 吸入送達のための核酸又はタンパク質を担持した肺サーファクタント粒子及びその製造方法 |
-
1999
- 1999-06-18 JP JP11172176A patent/JP2001002592A/ja active Pending
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