JP2000515546A5 - - Google Patents

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Publication number
JP2000515546A5
JP2000515546A5 JP1998507945A JP50794598A JP2000515546A5 JP 2000515546 A5 JP2000515546 A5 JP 2000515546A5 JP 1998507945 A JP1998507945 A JP 1998507945A JP 50794598 A JP50794598 A JP 50794598A JP 2000515546 A5 JP2000515546 A5 JP 2000515546A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1998507945A
Other languages
English (en)
Japanese (ja)
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JP2000515546A (ja
Filing date
Publication date
Priority claimed from US08/692,429 external-priority patent/US5831046A/en
Application filed filed Critical
Publication of JP2000515546A publication Critical patent/JP2000515546A/ja
Publication of JP2000515546A5 publication Critical patent/JP2000515546A5/ja
Pending legal-status Critical Current

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JP10507945A 1996-08-05 1997-07-31 新規ホウ素酸含有核酸類及び診断剤としてのそれらの使用 Pending JP2000515546A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/692,429 US5831046A (en) 1996-08-05 1996-08-05 Boronic acid-contaning nucleic acid monomers
US08/692,429 1996-08-05
PCT/US1997/012834 WO1998005672A1 (en) 1996-08-05 1997-07-31 Novel boronic acid-containing nucleic acids and their use as diagnostic agents

Publications (2)

Publication Number Publication Date
JP2000515546A JP2000515546A (ja) 2000-11-21
JP2000515546A5 true JP2000515546A5 (cg-RX-API-DMAC7.html) 2005-09-08

Family

ID=24780549

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10507945A Pending JP2000515546A (ja) 1996-08-05 1997-07-31 新規ホウ素酸含有核酸類及び診断剤としてのそれらの使用

Country Status (6)

Country Link
US (3) US5831046A (cg-RX-API-DMAC7.html)
EP (1) EP0923591A4 (cg-RX-API-DMAC7.html)
JP (1) JP2000515546A (cg-RX-API-DMAC7.html)
AU (1) AU729907B2 (cg-RX-API-DMAC7.html)
CA (1) CA2262618C (cg-RX-API-DMAC7.html)
WO (1) WO1998005672A1 (cg-RX-API-DMAC7.html)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US7041510B2 (en) * 1996-04-25 2006-05-09 Bioarray Solutions Ltd. System and method for programmable illumination pattern generation
US6630577B2 (en) 1996-08-05 2003-10-07 Prolinx, Inc. 1,2-Phenylenediboronic acid reagents and complexes
US6051251A (en) * 1997-11-20 2000-04-18 Alza Corporation Liposome loading method using a boronic acid compound
AU3199699A (en) * 1998-03-23 1999-10-18 Invitrogen Corporation Modified nucleotides and methods useful for nucleic acid sequencing
US6013783A (en) * 1999-03-19 2000-01-11 Prolinx Incorporated Boronic acid containing oligonucleotides and polynucleotides
CN1354752A (zh) * 1999-03-19 2002-06-19 坡林克斯股份有限公司 含硼酸的试剂和寡核苷酸
US20010049438A1 (en) * 1999-03-19 2001-12-06 Dix Connie Kim Purification of primer extension products
US6248884B1 (en) * 1999-06-03 2001-06-19 The Perkin-Elmer Corporation Extended rhodamine compounds useful as fluorescent labels
JP2001183368A (ja) * 1999-12-27 2001-07-06 Fuji Photo Film Co Ltd 固相担体表面へのdna断片の固定方法及びdnaチップ
US6686461B1 (en) 2000-03-22 2004-02-03 Solulink Bioscience, Inc. Triphosphate oligonucleotide modification reagents and uses thereof
US7102024B1 (en) 2000-08-01 2006-09-05 Schwartz David A Functional biopolymer modification reagents and uses thereof
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
CA2635452A1 (en) 2000-06-21 2001-12-27 Bioarray Solutions, Ltd. Looped probe design to control hybridization stringency
CA2419238A1 (en) * 2000-08-16 2002-02-21 University Of Alberta Non-pressurized methods for the preparation of conjugated solid supports for boronic acids
US6919382B2 (en) 2000-08-31 2005-07-19 The Governors Of The University Of Alberta Preparation and uses of conjugated solid supports for boronic acids
US20030027135A1 (en) * 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US20040121335A1 (en) * 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents associated with host versus graft and graft versus host rejections
WO2004060278A2 (en) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Methods for rapid identification of pathogens in humans and animals
US7666588B2 (en) * 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
JP2005505749A (ja) 2001-05-21 2005-02-24 アクララ バイオサイエンシーズ, インコーポレイテッド タンパク質を分析するための方法および組成物
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
US8073627B2 (en) * 2001-06-26 2011-12-06 Ibis Biosciences, Inc. System for indentification of pathogens
JP4377689B2 (ja) 2001-10-15 2009-12-02 バイオアレイ ソリューションズ リミテッド 同時尋問及び酵素仲介検出による多型遺伝子座の複合分析
WO2003045310A2 (en) 2001-11-21 2003-06-05 Applera Corporation Digital assay
US20050221318A1 (en) * 2002-03-15 2005-10-06 Gouliaev Alex H Building block forming a c-c bond upon reaction
WO2004047007A1 (en) 2002-11-15 2004-06-03 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
CA2513985C (en) * 2003-01-21 2012-05-29 Illumina Inc. Chemical reaction monitor
US8046171B2 (en) 2003-04-18 2011-10-25 Ibis Biosciences, Inc. Methods and apparatus for genetic evaluation
US8057993B2 (en) 2003-04-26 2011-11-15 Ibis Biosciences, Inc. Methods for identification of coronaviruses
US7964343B2 (en) * 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US7956175B2 (en) * 2003-09-11 2011-06-07 Ibis Biosciences, Inc. Compositions for use in identification of bacteria
US20060240412A1 (en) * 2003-09-11 2006-10-26 Hall Thomas A Compositions for use in identification of adenoviruses
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US20080138808A1 (en) * 2003-09-11 2008-06-12 Hall Thomas A Methods for identification of sepsis-causing bacteria
US7927796B2 (en) 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
CA2539824C (en) 2003-09-22 2015-02-03 Xinwen Wang Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
US7563569B2 (en) 2003-10-28 2009-07-21 Michael Seul Optimization of gene expression analysis using immobilized capture probes
JP2007509629A (ja) 2003-10-29 2007-04-19 バイオアレイ ソリューションズ リミテッド 二本鎖dnaの切断による複合核酸分析
US8163895B2 (en) 2003-12-05 2012-04-24 Ibis Biosciences, Inc. Compositions for use in identification of orthopoxviruses
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
US8119336B2 (en) * 2004-03-03 2012-02-21 Ibis Biosciences, Inc. Compositions for use in identification of alphaviruses
WO2005119255A2 (en) * 2004-05-12 2005-12-15 Applera Corporation Constrained cis-diol-borate bioconjugation system
EP2458619B1 (en) 2004-05-24 2017-08-02 Ibis Biosciences, Inc. Mass spectrometry with selective ion filtration by digital thresholding
US20050266411A1 (en) * 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
JP5038912B2 (ja) * 2005-02-16 2012-10-03 アナコール ファーマシューティカルズ,インコーポレイテッド ホウ素含有小分子
CA2600184A1 (en) 2005-03-03 2006-09-08 Isis Pharmaceuticals, Inc. Compositions for use in identification of adventitious viruses
US8084207B2 (en) * 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
ATE483825T1 (de) * 2005-04-13 2010-10-15 Ibis Biosciences Inc Zusammensetzungen für die identifizierung von adenoviren
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
WO2007014045A2 (en) * 2005-07-21 2007-02-01 Isis Pharmaceuticals, Inc. Methods for rapid identification and quantitation of nucleic acid variants
CN106008571A (zh) 2005-12-30 2016-10-12 安纳考尔医药公司 含硼的小分子
DK1988779T5 (en) 2006-02-16 2016-10-10 Anacor Pharmaceuticals Inc SMALL boron MOLECULES AS ANTI-INFLAMMATORY AGENTS
JP5420412B2 (ja) * 2006-09-14 2014-02-19 アイビス バイオサイエンシズ インコーポレイティッド 病原体の同定のための標的全ゲノム増幅方法
WO2008104002A2 (en) * 2007-02-23 2008-08-28 Ibis Biosciences, Inc. Methods for rapid forensic dna analysis
US20100204266A1 (en) * 2007-03-23 2010-08-12 Ibis Biosciences, INC Compositions for use in identification of mixed populations of bioagents
WO2008151023A2 (en) 2007-06-01 2008-12-11 Ibis Biosciences, Inc. Methods and compositions for multiple displacement amplification of nucleic acids
JO3396B1 (ar) 2007-06-20 2019-10-20 Anacor Pharmaceuticals Inc جزيئات صغيرة تحتوي على البورون
US8877156B2 (en) 2007-06-26 2014-11-04 New York University Contrast agents anchored by thiols on nanoparticles
US9096856B2 (en) * 2007-07-19 2015-08-04 Georgia State University Research Foundation, Inc. Nucleotides and aptamers containing boronic acid groups having biased binding to glycosylated proteins, and uses thereof
EP2564857B1 (en) 2008-03-06 2017-05-03 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-inflammatory agents
US20100256092A1 (en) * 2008-05-12 2010-10-07 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
WO2010028005A1 (en) 2008-09-04 2010-03-11 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
WO2010027975A1 (en) * 2008-09-04 2010-03-11 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
WO2010033625A1 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Microplate handling systems and related computer program products and methods
US8550694B2 (en) 2008-09-16 2013-10-08 Ibis Biosciences, Inc. Mixing cartridges, mixing stations, and related kits, systems, and methods
WO2010033627A2 (en) * 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Sample processing units, systems, and related methods
WO2010045503A1 (en) * 2008-10-15 2010-04-22 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-protozoal agents
KR20110111407A (ko) * 2008-12-17 2011-10-11 아나코르 파마슈티칼스 인코포레이티드 (s)-3-아미노메틸-7-(3-히드록시-프로폭시)-3h-벤조〔c〕〔1,2〕옥사보롤-1-올의 다형태
EP2396803A4 (en) 2009-02-12 2016-10-26 Ibis Biosciences Inc IONIZATION PROBE ASSEMBLIES
US8950604B2 (en) * 2009-07-17 2015-02-10 Ibis Biosciences, Inc. Lift and mount apparatus
US9194877B2 (en) 2009-07-17 2015-11-24 Ibis Biosciences, Inc. Systems for bioagent indentification
EP2458995A1 (en) * 2009-07-28 2012-06-06 Anacor Pharmaceuticals, Inc. Trisubstituted boron-containing molecules
AP4039A (en) * 2009-08-14 2017-02-28 Daitao Chen Boron-containing small molecules as antiprotozoal agents
MX2012002031A (es) * 2009-08-19 2012-07-04 Anacor Pharmaceuticals Inc Moleculas pequeñas que contienen boro como agentes antiprotozoarios.
WO2011037731A1 (en) * 2009-09-25 2011-03-31 Anacor Pharmaceuticals, Inc. Boron containing small molecules
WO2011041695A1 (en) * 2009-10-02 2011-04-07 Ibis Biosciences, Inc. Determination of methylation status of polynucleotides
EP2957641B1 (en) * 2009-10-15 2017-05-17 Ibis Biosciences, Inc. Multiple displacement amplification
WO2011049971A1 (en) 2009-10-20 2011-04-28 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as antiprotozoal agents
US20110212918A1 (en) * 2009-11-11 2011-09-01 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
WO2011094450A1 (en) 2010-01-27 2011-08-04 Anacor Pharmaceuticals, Inc Boron-containing small molecules
US8623911B2 (en) 2010-03-19 2014-01-07 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-protozoal agent
BR112013005426B1 (pt) 2010-09-07 2021-08-24 Anacor Pharmaceuticals, Inc Composto, composição, combinação, e, formulação farmacêutica
US11447506B2 (en) 2016-05-09 2022-09-20 Anacor Pharmaceuticals, Inc. Crystal forms of crisaborole in free form and preparation method and use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4711955A (en) * 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
US5241060A (en) * 1982-06-23 1993-08-31 Enzo Diagnostics, Inc. Base moiety-labeled detectable nucleatide
US5177198A (en) * 1989-11-30 1993-01-05 University Of N.C. At Chapel Hill Process for preparing oligoribonucleoside and oligodeoxyribonucleoside boranophosphates
US5362732A (en) * 1989-12-20 1994-11-08 University Of North Carolina At Chapel Hill Boronated compounds
US5466679A (en) * 1993-05-17 1995-11-14 The Ohio State University Research Foundation Carboranyl uridines and their use in boron neutron capture therapy
US6180766B1 (en) * 1993-12-02 2001-01-30 Raymond F. Schinazi Nucleosides and oligonucleotides containing boron clusters
US5594111A (en) * 1994-01-28 1997-01-14 Prolinx, Inc. Phenylboronic acid complexes for bioconjugate preparation
PT741734E (pt) * 1994-01-28 2001-09-28 Prolinx Inc Complexos de acido fenilboronico
US5594151A (en) * 1994-01-28 1997-01-14 Prolinx, Inc. Phenylboronic acid complexing reagents derived from aminosalicylic acid
US5473928A (en) * 1994-04-15 1995-12-12 Teitzel; Frederick E. Tool and method for straightening a panel
US5595878A (en) * 1995-06-02 1997-01-21 Boron Biologicals, Inc. Detection of biopolymers and biooligomers with boron hydride labels

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