JP2000514456A5 - - Google Patents

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Publication number
JP2000514456A5
JP2000514456A5 JP1998506095A JP50609598A JP2000514456A5 JP 2000514456 A5 JP2000514456 A5 JP 2000514456A5 JP 1998506095 A JP1998506095 A JP 1998506095A JP 50609598 A JP50609598 A JP 50609598A JP 2000514456 A5 JP2000514456 A5 JP 2000514456A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998506095A
Other languages
English (en)
Japanese (ja)
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JP2000514456A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/011845 external-priority patent/WO1998002436A1/en
Publication of JP2000514456A publication Critical patent/JP2000514456A/ja
Publication of JP2000514456A5 publication Critical patent/JP2000514456A5/ja
Ceased legal-status Critical Current

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JP10506095A 1996-07-15 1997-07-08 ファルネシルプロテイントランスフェラーゼのチアジオキソベンゾジアゼピン阻害剤 Ceased JP2000514456A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2178696P 1996-07-15 1996-07-15
US60/021,786 1996-07-15
PCT/US1997/011845 WO1998002436A1 (en) 1996-07-15 1997-07-08 Thiadioxobenzodiazepine inhibitors of farnesyl protein transferase

Publications (2)

Publication Number Publication Date
JP2000514456A JP2000514456A (ja) 2000-10-31
JP2000514456A5 true JP2000514456A5 (OSRAM) 2005-02-10

Family

ID=21806140

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10506095A Ceased JP2000514456A (ja) 1996-07-15 1997-07-08 ファルネシルプロテイントランスフェラーゼのチアジオキソベンゾジアゼピン阻害剤

Country Status (6)

Country Link
US (1) US6624157B2 (OSRAM)
EP (1) EP0918771A4 (OSRAM)
JP (1) JP2000514456A (OSRAM)
AU (1) AU709409B2 (OSRAM)
CA (1) CA2260216A1 (OSRAM)
WO (1) WO1998002436A1 (OSRAM)

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WO2009151683A2 (en) 2008-03-12 2009-12-17 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
WO2010057006A1 (en) 2008-11-13 2010-05-20 Link Medicine Corporation Azaquinolinone derivatives and uses thereof
WO2010114780A1 (en) 2009-04-01 2010-10-07 Merck Sharp & Dohme Corp. Inhibitors of akt activity
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JP6073677B2 (ja) 2009-06-12 2017-02-01 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド 縮合複素環式化合物およびそれらの使用
PH12012500713A1 (en) 2009-10-14 2012-11-26 Merck Sharp & Dohme Substituted piperidines that increase p53 activity and the uses thereof
EP2519517B1 (en) 2009-12-29 2015-03-25 Dana-Farber Cancer Institute, Inc. Type ii raf kinase inhibitors
EP2547661A2 (en) 2010-03-16 2013-01-23 Dana-Farber Cancer Institute, Inc. Indazole compounds and their uses
EP2584903B1 (en) 2010-06-24 2018-10-24 Merck Sharp & Dohme Corp. Novel heterocyclic compounds as erk inhibitors
US8518907B2 (en) 2010-08-02 2013-08-27 Merck Sharp & Dohme Corp. RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)
RU2624045C2 (ru) 2010-08-17 2017-06-30 Сирна Терапьютикс,Инк ОПОСРЕДУЕМОЕ РНК-ИНТЕРФЕРЕНЦИЕЙ ИНГИБИРОВАНИЕ ЭКСПРЕССИИ ГЕНОВ ВИРУСА ГЕПАТИТА B (HBV) С ПРИМЕНЕНИЕМ МАЛОЙ ИНТЕРФЕРИРУЮЩЕЙ НУКЛЕИНОВОЙ КИСЛОТЫ (миНК)
EP2608669B1 (en) 2010-08-23 2016-06-22 Merck Sharp & Dohme Corp. NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
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US11098059B2 (en) 2017-11-08 2021-08-24 Merck Sharp & Dohme Corp. PRMT5 inhibitors
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EP3833667B1 (en) 2018-08-07 2024-03-13 Merck Sharp & Dohme LLC Prmt5 inhibitors
EP3833668B1 (en) 2018-08-07 2025-03-19 Merck Sharp & Dohme LLC Prmt5 inhibitors
AU2019413694B2 (en) 2018-12-28 2025-03-20 Dana-Farber Cancer Institute, Inc. Inhibitors of cyclin-dependent kinase 7 and uses thereof
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US20240325409A1 (en) * 2023-02-27 2024-10-03 Enanta Pharmaceuticals, Inc. Fused Heterotetracyclic Antiviral Agents
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Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2920385B2 (ja) * 1988-08-18 1999-07-19 武田薬品工業株式会社 1,2,5‐ベンゾチアジアゼピン誘導体,その製造法および用途
JPH02111766A (ja) * 1988-10-20 1990-04-24 Taiho Yakuhin Kogyo Kk ベンゾチアジアゼピン誘導体及びその塩
US5843941A (en) * 1993-05-14 1998-12-01 Genentech, Inc. Ras farnesyl transferase inhibitors
US6011029A (en) * 1996-02-26 2000-01-04 Bristol-Myers Squibb Company Inhibitors of farnesyl protein transferase
US6156746A (en) * 1998-08-25 2000-12-05 Bristol-Myers Squibb Company 1,2,5-benzothiadiazepine-1,1-dioxides with n-2 imidazolylalkyl substituents

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