JP2000514313A - バイオマスを培養する方法 - Google Patents
バイオマスを培養する方法Info
- Publication number
- JP2000514313A JP2000514313A JP10517891A JP51789198A JP2000514313A JP 2000514313 A JP2000514313 A JP 2000514313A JP 10517891 A JP10517891 A JP 10517891A JP 51789198 A JP51789198 A JP 51789198A JP 2000514313 A JP2000514313 A JP 2000514313A
- Authority
- JP
- Japan
- Prior art keywords
- methanol
- culturing
- stage
- culture
- supply
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002028 Biomass Substances 0.000 title claims description 26
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims abstract description 333
- 238000012258 culturing Methods 0.000 claims abstract description 53
- 238000000034 method Methods 0.000 claims abstract description 52
- 238000005273 aeration Methods 0.000 claims abstract description 11
- 244000005700 microbiome Species 0.000 claims abstract description 7
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229910052799 carbon Inorganic materials 0.000 claims abstract description 6
- 238000010979 pH adjustment Methods 0.000 claims abstract description 4
- 239000003513 alkali Substances 0.000 claims abstract 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 18
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 7
- 239000001301 oxygen Substances 0.000 claims description 7
- 229910052760 oxygen Inorganic materials 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 3
- 238000010923 batch production Methods 0.000 claims 1
- 238000009825 accumulation Methods 0.000 abstract description 2
- 239000000543 intermediate Substances 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 239000002609 medium Substances 0.000 description 18
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 12
- 229910052500 inorganic mineral Inorganic materials 0.000 description 10
- 235000010755 mineral Nutrition 0.000 description 10
- 239000011707 mineral Substances 0.000 description 10
- 150000003839 salts Chemical class 0.000 description 10
- 238000011081 inoculation Methods 0.000 description 9
- 235000013619 trace mineral Nutrition 0.000 description 8
- 239000011573 trace mineral Substances 0.000 description 8
- 238000009395 breeding Methods 0.000 description 7
- 230000001488 breeding effect Effects 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- 229910052757 nitrogen Inorganic materials 0.000 description 6
- 239000000758 substrate Substances 0.000 description 5
- 239000012670 alkaline solution Substances 0.000 description 4
- 239000000523 sample Substances 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 238000000855 fermentation Methods 0.000 description 3
- 230000004151 fermentation Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000001850 reproductive effect Effects 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- UZFMOKQJFYMBGY-UHFFFAOYSA-N 4-hydroxy-TEMPO Chemical compound CC1(C)CC(O)CC(C)(C)N1[O] UZFMOKQJFYMBGY-UHFFFAOYSA-N 0.000 description 2
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 2
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 2
- 235000011114 ammonium hydroxide Nutrition 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000002032 methanolic fraction Substances 0.000 description 2
- 229920001451 polypropylene glycol Polymers 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonium chloride Substances [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 1
- 241000589323 Methylobacterium Species 0.000 description 1
- 241000277331 Salmonidae Species 0.000 description 1
- 241000272534 Struthio camelus Species 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 239000000908 ammonium hydroxide Substances 0.000 description 1
- 239000002518 antifoaming agent Substances 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000004883 computer application Methods 0.000 description 1
- 238000012136 culture method Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/32—Processes using, or culture media containing, lower alkanols, i.e. C1 to C6
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1996142105 DE19642105A1 (de) | 1996-10-12 | 1996-10-12 | Verfahren zur Anzucht von Biomasse |
| DE19642105.5 | 1996-10-12 | ||
| PCT/DE1997/002277 WO1998016624A1 (de) | 1996-10-12 | 1997-10-04 | Verfahren zur anzucht von biomasse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2000514313A true JP2000514313A (ja) | 2000-10-31 |
Family
ID=7808550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10517891A Pending JP2000514313A (ja) | 1996-10-12 | 1997-10-04 | バイオマスを培養する方法 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0932660A1 (de) |
| JP (1) | JP2000514313A (de) |
| DE (1) | DE19642105A1 (de) |
| WO (1) | WO1998016624A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19910143C2 (de) * | 1999-02-26 | 2001-03-15 | Saechsisches Inst Fuer Angewan | Verfahren zur kontinuierlichen biotechnischen Herstellung von Poly-beta-hydroxybuttersäure |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5217114B2 (de) * | 1973-05-11 | 1977-05-13 | ||
| DE2633451C3 (de) * | 1976-07-24 | 1980-08-28 | Hoechst Ag, 6000 Frankfurt | Herstellung von Bakterienzellmasse |
| EP0144474B1 (de) * | 1983-12-09 | 1987-04-01 | Fabriques De Tabac Reunies S.A. | Kontinuierliches Gärungsverfahren |
| AU583978B2 (en) * | 1986-03-10 | 1989-05-11 | Phillips Petroleum Company | Fermentation of bacteria at high productivities |
| DD293138A5 (de) * | 1990-03-02 | 1991-08-22 | Chemie Ag Bitterfeld-Wolfen,De | Verfahren zur herstellung von ubichinon-10 mittels bakterien |
| US5302525A (en) * | 1992-11-23 | 1994-04-12 | National Research Council Of Canada | Methylobacterium extorquwns microorganism useful for the preparation of poly-β-hydroxybutyric acid polymers |
-
1996
- 1996-10-12 DE DE1996142105 patent/DE19642105A1/de not_active Withdrawn
-
1997
- 1997-10-04 WO PCT/DE1997/002277 patent/WO1998016624A1/de not_active Application Discontinuation
- 1997-10-04 EP EP97910254A patent/EP0932660A1/de not_active Withdrawn
- 1997-10-04 JP JP10517891A patent/JP2000514313A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0932660A1 (de) | 1999-08-04 |
| WO1998016624A1 (de) | 1998-04-23 |
| DE19642105A1 (de) | 1998-04-16 |
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