JP2000508298A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2000508298A5 JP2000508298A5 JP1997535786A JP53578697A JP2000508298A5 JP 2000508298 A5 JP2000508298 A5 JP 2000508298A5 JP 1997535786 A JP1997535786 A JP 1997535786A JP 53578697 A JP53578697 A JP 53578697A JP 2000508298 A5 JP2000508298 A5 JP 2000508298A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19613976A DE19613976C1 (de) | 1996-04-09 | 1996-04-09 | Thalidomid-Prodrugs mit immunmodulatorischer Wirkung |
| DE19613976.7 | 1996-04-09 | ||
| PCT/EP1997/001475 WO1997037988A1 (de) | 1996-04-09 | 1997-03-22 | Acylierte n-hydroxymethyl thalidomid-prodrugs mit immunomodulatorischer wirkung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2000508298A JP2000508298A (ja) | 2000-07-04 |
| JP2000508298A5 true JP2000508298A5 (enExample) | 2004-12-02 |
Family
ID=7790778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9535786A Withdrawn JP2000508298A (ja) | 1996-04-09 | 1997-03-22 | 免疫調節作用を有するアシル化ｎ―ヒドロキシメチルサリドマイドプロドラッグ |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6417197B1 (enExample) |
| EP (1) | EP0892794B1 (enExample) |
| JP (1) | JP2000508298A (enExample) |
| CN (1) | CN1102931C (enExample) |
| AT (1) | ATE212989T1 (enExample) |
| AU (1) | AU707144B2 (enExample) |
| DE (2) | DE19613976C1 (enExample) |
| DK (1) | DK0892794T3 (enExample) |
| ES (1) | ES2171923T3 (enExample) |
| HU (1) | HUP9902181A3 (enExample) |
| PT (1) | PT892794E (enExample) |
| WO (1) | WO1997037988A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19613976C1 (de) * | 1996-04-09 | 1997-11-20 | Gruenenthal Gmbh | Thalidomid-Prodrugs mit immunmodulatorischer Wirkung |
| EP0914123A4 (en) * | 1996-05-29 | 2000-10-11 | Prototek Inc | THALIDOMIDE PRODUCTS AND METHODS OF USING SAID PRODUCTS AS T CELL MODIFIERS |
| HU228769B1 (en) * | 1996-07-24 | 2013-05-28 | Celgene Corp | Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha |
| DE19743968C2 (de) * | 1997-10-06 | 2002-07-11 | Gruenenthal Gmbh | Intravenöse Applikationsform von Thalidomid zur Therapie immunologischer Erkrankungen |
| US5955476A (en) * | 1997-11-18 | 1999-09-21 | Celgene Corporation | Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels |
| DE69834668T2 (de) * | 1997-11-18 | 2007-01-11 | Celgene Corp. | Substituierte 2-(2,6-dioxo-3-fluoropiperidine-3-yl)-isoindoline und ihre Verwendung zum reduzieren des TNF-alpha spiegels |
| AU4515001A (en) * | 1999-12-02 | 2001-06-18 | Regents Of The University Of Michigan, The | Compositions and methods for locally treating inflammatory diseases |
| US7091353B2 (en) | 2000-12-27 | 2006-08-15 | Celgene Corporation | Isoindole-imide compounds, compositions, and uses thereof |
| AU2002306596B2 (en) * | 2001-02-27 | 2008-01-17 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Analogs of thalidomide as potential angiogenesis inhibitors |
| CN100488959C (zh) * | 2003-03-27 | 2009-05-20 | 天津和美生物技术有限公司 | 水溶性的酞胺哌啶酮衍生物 |
| WO2005016326A2 (en) * | 2003-07-11 | 2005-02-24 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Analogs of thalidomide as potential angiogenesis inhibitors |
| CN100398534C (zh) * | 2003-09-15 | 2008-07-02 | 天津和美生物技术有限公司 | 合成酞胺哌啶酮及其衍生物的方法 |
| WO2005028436A2 (en) | 2003-09-17 | 2005-03-31 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Thalidomide analogs as tnf-alpha modulators |
| US8952895B2 (en) | 2011-06-03 | 2015-02-10 | Apple Inc. | Motion-based device operations |
| KR20060118472A (ko) * | 2003-10-16 | 2006-11-23 | 카이론 코포레이션 | 치환 벤자졸 및 ｒａｆ 키나아제의 저해제로서 그것의 사용 |
| ITMI20041113A1 (it) * | 2004-06-01 | 2004-09-01 | Antibioticos Spa | Processo per la sintesi della talidomide |
| US20070155791A1 (en) * | 2005-12-29 | 2007-07-05 | Zeldis Jerome B | Methods for treating cutaneous lupus using aminoisoindoline compounds |
| CA2648216C (en) | 2006-04-13 | 2016-06-07 | Michael Gutschow | Tetrahalogenated compounds useful as inhibitors of angiogenesis |
| CA2741299C (en) | 2008-10-29 | 2017-03-28 | Celgene Corporation | Isoindoline compounds for use in the treatment of cancer |
| US8927725B2 (en) | 2011-12-02 | 2015-01-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Thio compounds |
| HRP20201789T1 (hr) * | 2016-01-08 | 2021-01-22 | Celgene Corporation | Antiproliferativni spojevi, te njihovi farmaceutski pripravci i uporabe |
| WO2019036839A1 (zh) * | 2017-08-21 | 2019-02-28 | 诺瑞特国际药业股份有限公司 | 泊马度胺衍生物及其制备方法 |
| CN111499610A (zh) * | 2019-01-31 | 2020-08-07 | 南京诺瑞特医药科技有限公司 | 泊马度胺前体药物盐的多晶型物 |
| EP3771711A1 (en) | 2019-07-29 | 2021-02-03 | Bayer Animal Health GmbH | Pyrazole derivatives for controlling arthropods |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1531492A (en) * | 1991-02-14 | 1992-09-15 | Rockefeller University, The | Method for controlling abnormal concentration tnf alpha in human tissues |
| WO1992018496A1 (de) * | 1991-04-17 | 1992-10-29 | Grünenthal GmbH | Neue thalidomidderivate, ein verfahren zu deren herstellung sowie die verwendung derselben in arzneimitteln |
| DE19613976C1 (de) * | 1996-04-09 | 1997-11-20 | Gruenenthal Gmbh | Thalidomid-Prodrugs mit immunmodulatorischer Wirkung |
-
1996
- 1996-04-09 DE DE19613976A patent/DE19613976C1/de not_active Expired - Fee Related
-
1997
- 1997-03-22 EP EP97916380A patent/EP0892794B1/de not_active Expired - Lifetime
- 1997-03-22 US US09/155,896 patent/US6417197B1/en not_active Expired - Fee Related
- 1997-03-22 CN CN97193682A patent/CN1102931C/zh not_active Expired - Fee Related
- 1997-03-22 DE DE59706313T patent/DE59706313D1/de not_active Expired - Fee Related
- 1997-03-22 JP JP9535786A patent/JP2000508298A/ja not_active Withdrawn
- 1997-03-22 PT PT97916380T patent/PT892794E/pt unknown
- 1997-03-22 HU HU9902181A patent/HUP9902181A3/hu unknown
- 1997-03-22 DK DK97916380T patent/DK0892794T3/da active
- 1997-03-22 AT AT97916380T patent/ATE212989T1/de not_active IP Right Cessation
- 1997-03-22 WO PCT/EP1997/001475 patent/WO1997037988A1/de not_active Ceased
- 1997-03-22 AU AU25052/97A patent/AU707144B2/en not_active Ceased
- 1997-03-22 ES ES97916380T patent/ES2171923T3/es not_active Expired - Lifetime