JP2000507578A5 - - Google Patents

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Publication number
JP2000507578A5
JP2000507578A5 JP1997535395A JP53539597A JP2000507578A5 JP 2000507578 A5 JP2000507578 A5 JP 2000507578A5 JP 1997535395 A JP1997535395 A JP 1997535395A JP 53539597 A JP53539597 A JP 53539597A JP 2000507578 A5 JP2000507578 A5 JP 2000507578A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997535395A
Other languages
English (en)
Japanese (ja)
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JP2000507578A (ja
JP4759762B2 (ja
Filing date
Publication date
Priority claimed from US08/626,259 external-priority patent/US5717092A/en
Application filed filed Critical
Publication of JP2000507578A publication Critical patent/JP2000507578A/ja
Publication of JP2000507578A5 publication Critical patent/JP2000507578A5/ja
Application granted granted Critical
Publication of JP4759762B2 publication Critical patent/JP4759762B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP53539597A 1996-03-29 1997-03-24 改良された多剤耐性活性を有するｎ―（２―オキソアセチルまたはスルホニル）―ピロリジン／ピペリジン―２―カルボン酸誘導体 Expired - Fee Related JP4759762B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/626,259 US5717092A (en) 1996-03-29 1996-03-29 Compounds with improved multi-drug resistance activity
US08/626,259 1996-03-29
PCT/US1997/004916 WO1997036869A1 (en) 1996-03-29 1997-03-24 N-(2 oxoacetyl or sulphonyl)-pyrrolidine/piperidine-2-carboxylic acid derivatives with improved multi-drug resistance activity

Publications (3)

Publication Number Publication Date
JP2000507578A JP2000507578A (ja) 2000-06-20
JP2000507578A5 true JP2000507578A5 (OSRAM) 2004-12-02
JP4759762B2 JP4759762B2 (ja) 2011-08-31

Family

ID=24509627

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53539597A Expired - Fee Related JP4759762B2 (ja) 1996-03-29 1997-03-24 改良された多剤耐性活性を有するｎ―（２―オキソアセチルまたはスルホニル）―ピロリジン／ピペリジン―２―カルボン酸誘導体

Country Status (11)

Country Link
US (2) US5717092A (OSRAM)
EP (1) EP0891331B1 (OSRAM)
JP (1) JP4759762B2 (OSRAM)
AT (1) ATE251140T1 (OSRAM)
AU (1) AU2346597A (OSRAM)
CA (1) CA2249369A1 (OSRAM)
DE (1) DE69725293T2 (OSRAM)
DK (1) DK0891331T3 (OSRAM)
ES (1) ES2208890T3 (OSRAM)
PT (1) PT891331E (OSRAM)
WO (1) WO1997036869A1 (OSRAM)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030036654A1 (en) * 1994-08-18 2003-02-20 Holt Dennis A. Synthetic multimerizing agents
US6150527A (en) * 1994-08-18 2000-11-21 Ariad Pharmaceuticals, Inc. Synthetic multimerizing agents
US6133456A (en) * 1994-08-18 2000-10-17 Ariad Gene Therapeutics, Inc. Synthetic multimerizing agents
US5795877A (en) * 1996-12-31 1998-08-18 Guilford Pharmaceuticals Inc. Inhibitors of NAALADase enzyme activity
US6218424B1 (en) * 1996-09-25 2001-04-17 Gpi Nil Holdings, Inc. Heterocyclic ketone and thioester compounds and uses
US5786378A (en) * 1996-09-25 1998-07-28 Gpi Nil Holdings, Inc. Heterocyclic thioesters
US5801187A (en) 1996-09-25 1998-09-01 Gpi-Nil Holdings, Inc. Heterocyclic esters and amides
JP2002515050A (ja) * 1996-12-31 2002-05-21 ジーピーアイ エヌアイエル ホールディングス インコーポレイテッド ヘテロ環式チオエステルのｎ−結合尿素およびカルバメート
US5935989A (en) 1996-12-31 1999-08-10 Gpi Nil Holdings Inc. N-linked ureas and carbamates of heterocyclic thioesters
US6121273A (en) * 1996-12-31 2000-09-19 Gpi Nil Holdings, Inc N-linked sulfonamides of heterocyclic thioesters
US5874449A (en) * 1996-12-31 1999-02-23 Gpi Nil Holdings, Inc. N-linked sulfonamides of heterocyclic thioesters
US6242468B1 (en) 1997-02-27 2001-06-05 Jia-He Li Carbamate and urea compositions and neurotrophic uses
US5846979A (en) * 1997-02-28 1998-12-08 Gpi Nil Holdings, Inc. N-oxides of heterocyclic esters, amides, thioesters, and ketones
US20010049381A1 (en) 1997-06-04 2001-12-06 Gpl Nil Holdings, Inc., Pyrrolidine derivative hair growth compositions and uses
US5945441A (en) * 1997-06-04 1999-08-31 Gpi Nil Holdings, Inc. Pyrrolidine carboxylate hair revitalizing agents
US6852496B1 (en) * 1997-08-12 2005-02-08 Oregon Health And Science University Methods of screening for agents that promote nerve cell growth
US6369070B1 (en) 1998-04-08 2002-04-09 Eli Lilly And Company Methods for inhibiting mrp1
AU3468099A (en) 1998-04-08 1999-10-25 Eli Lilly And Company Methods for inhibiting mrp1
US6410041B1 (en) 1998-04-28 2002-06-25 Trustees Of Tufts College Culturing cells in presence of amphipathic weak bases and/or cations and multiple drug resistance inhibitor containing reserpine
US20020131972A1 (en) * 1998-05-21 2002-09-19 Daniel Sem Multi-partite ligands and methods of identifying and using same
JP2002516857A (ja) * 1998-06-02 2002-06-11 ブリストルーマイヤーズ スクイブ カンパニー 神経栄養性ジフルオロアミド剤
HUP0102935A3 (en) 1998-06-03 2002-01-28 Gpi Nil Holdings Inc Wilmingto N-linked sulfonamides of n-heterocyclic carboxylic acids or carboxylic acid isosteres and pharmaceutical compositions containing them
US6331537B1 (en) 1998-06-03 2001-12-18 Gpi Nil Holdings, Inc. Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds
US6300341B1 (en) 1998-09-30 2001-10-09 The Procter & Gamble Co. 2-substituted heterocyclic sulfonamides
US6307049B1 (en) 1998-09-30 2001-10-23 The Procter & Gamble Co. Heterocyclic 2-substituted ketoamides
JP2002525352A (ja) * 1998-09-30 2002-08-13 ザ、プロクター、エンド、ギャンブル、カンパニー ２−置換ケトアミド
US6228872B1 (en) 1998-11-12 2001-05-08 Bristol-Myers Squibb Company Neurotrophic diamide and carbamate agents
US6358531B1 (en) * 1999-02-01 2002-03-19 The Curators Of The University Of Missouri Method for preparing porous shells or gels from glass particles
WO2001010821A1 (en) * 1999-08-05 2001-02-15 The Procter & Gamble Company Multivalent exocyclic diketo compounds
US6670373B1 (en) 1999-10-07 2003-12-30 Eli Lilly And Company Compounds and method for inhibiting MRP1
US7253169B2 (en) 1999-11-12 2007-08-07 Gliamed, Inc. Aza compounds, pharmaceutical compositions and methods of use
US6417189B1 (en) 1999-11-12 2002-07-09 Gpi Nil Holdings, Inc. AZA compounds, pharmaceutical compositions and methods of use
US6818643B1 (en) 1999-12-08 2004-11-16 Bristol-Myers Squibb Company Neurotrophic bicyclic diamides
JP2003518122A (ja) 1999-12-21 2003-06-03 ジーピーアイ エヌアイエル ホールディングズ インコーポレーテッド ヒダントイン誘導体化合物、医薬合成品およびこれらの使用方法
US6376514B1 (en) 2000-10-17 2002-04-23 The Procter & Gamble Co. Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US6593362B2 (en) 2001-05-21 2003-07-15 Guilford Pharmaceuticals Inc. Non-peptidic cyclophilin binding compounds and their use
MXPA03011095A (es) * 2001-05-29 2005-04-28 Guilford Pharm Inc Metodo para tratar una lesion nerviosa causada por cirugia.
US7653490B2 (en) * 2001-09-10 2010-01-26 Triad Liquidating Company LLC Nuclear magnetic resonance assembly of chemical entities
AU2002363523A1 (en) * 2001-11-07 2003-05-19 Pharmacia Corporation Methods of promoting uptake and nuclear accumulation of polyamides in eukaryotic cells
US6635892B2 (en) * 2002-01-24 2003-10-21 Pei Electronics, Inc. Compact integrated infrared scene projector
US20030180797A1 (en) * 2002-03-20 2003-09-25 Lin Yu Identification of ligands for a receptor family and related methods
EP1490098B1 (en) * 2002-03-25 2010-03-17 Technologie Biolactis Inc. Chemotherapeutic agents as anti-cancer vaccine adjuvants and therapeutic methods thereof
US7825136B2 (en) 2003-07-10 2010-11-02 Vertex Pharmaceuticals Incorporated Potentiators of antibacterial activity
CN1281210C (zh) * 2003-11-29 2006-10-25 胡汛 五味子乙素在制备治疗肿瘤药物中的应用
US20060189551A1 (en) * 2004-10-04 2006-08-24 Duke University Combination therapies for fungal pathogens
GT200500368A (es) * 2004-12-20 2006-07-13 Analogos de rapamicina y los usos de los mismos en el tratamiento de trastornos neurologicos, proliferativos e inflamatorios
CN101084226A (zh) 2004-12-20 2007-12-05 惠氏公司 雷帕霉素衍生物及其治疗神经紊乱的用途
JP5767900B2 (ja) 2011-08-24 2015-08-26 株式会社東芝 水中溶接装置及び方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920218A (en) * 1988-10-12 1990-04-24 Merck & Co., Inc. Novel hydroxide mediated FK-506 rearrangement process
DE4015255A1 (de) * 1990-05-12 1991-11-14 Hoechst Ag Oxalyl-aminosaeurederivate, verfahren zu ihrer herstellung und ihrer verwendung als arzneimittel zur inhibierung der prolyl-hydroxylase
US5192773A (en) * 1990-07-02 1993-03-09 Vertex Pharmaceuticals, Inc. Immunosuppressive compounds
GB2247456A (en) * 1990-09-03 1992-03-04 Fujisawa Pharmaceutical Co Tetrahydropyrane compounds, a process for their production and a pharmaceutical composition containing the same
WO1992019593A1 (en) * 1991-05-09 1992-11-12 Vertex Pharmaceuticals Incorporated Novel immunosuppressive compounds
US5620971A (en) * 1991-05-09 1997-04-15 Vertex Pharmaceuticals Incorporated Biologically active acylated amino acid derivatives
US5250678A (en) * 1991-05-13 1993-10-05 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
AU2152092A (en) * 1991-06-24 1993-01-25 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
JPH08501646A (ja) * 1992-09-07 1996-02-20 マイコー・テクノロジイ・リミテッド 回折面データ検出器
NZ314207A (en) * 1992-09-28 2000-12-22 Vertex Pharma 1-(2-Oxoacetyl)-piperidine-2-carboxylic acid derivatives as multi drug resistant cancer cell sensitizers
AU3367995A (en) * 1994-08-18 1996-03-14 Ariad Pharmaceuticals, Inc. New multimerizing agents
US5859031A (en) * 1995-06-07 1999-01-12 Gpi Nil Holdings, Inc. Small molecule inhibitors of rotamase enzyme activity

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