JP2000506163A5 - - Google Patents

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Publication number
JP2000506163A5
JP2000506163A5 JP1997531784A JP53178497A JP2000506163A5 JP 2000506163 A5 JP2000506163 A5 JP 2000506163A5 JP 1997531784 A JP1997531784 A JP 1997531784A JP 53178497 A JP53178497 A JP 53178497A JP 2000506163 A5 JP2000506163 A5 JP 2000506163A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1997531784A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000506163A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/002568 external-priority patent/WO1997032846A1/en
Publication of JP2000506163A publication Critical patent/JP2000506163A/ja
Publication of JP2000506163A5 publication Critical patent/JP2000506163A5/ja
Withdrawn legal-status Critical Current

Links

JP9531784A 1996-03-08 1997-03-03 結合組織分解に関連する疾病の治療に有用な新規のヒドロキサム酸誘導体 Withdrawn JP2000506163A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1309896P 1996-03-08 1996-03-08
US60/013,098 1996-03-08
PCT/US1997/002568 WO1997032846A1 (en) 1996-03-08 1997-03-03 Hydroxamic acid derivatives for use with the treatment of diseases related to connective tissue degradation

Publications (2)

Publication Number Publication Date
JP2000506163A JP2000506163A (ja) 2000-05-23
JP2000506163A5 true JP2000506163A5 (enExample) 2004-11-25

Family

ID=21758301

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9531784A Withdrawn JP2000506163A (ja) 1996-03-08 1997-03-03 結合組織分解に関連する疾病の治療に有用な新規のヒドロキサム酸誘導体

Country Status (23)

Country Link
US (1) US5712300A (enExample)
EP (1) EP0898562B1 (enExample)
JP (1) JP2000506163A (enExample)
KR (1) KR19990087597A (enExample)
CN (1) CN1210517A (enExample)
AT (1) ATE231490T1 (enExample)
AU (1) AU707180B2 (enExample)
BR (1) BR9707947A (enExample)
DE (1) DE69718634T2 (enExample)
DK (1) DK0898562T3 (enExample)
ES (1) ES2191823T3 (enExample)
ID (1) ID16144A (enExample)
MY (1) MY117762A (enExample)
NO (1) NO312956B1 (enExample)
NZ (1) NZ330922A (enExample)
PE (1) PE55698A1 (enExample)
PL (1) PL328693A1 (enExample)
PT (1) PT898562E (enExample)
RU (1) RU2168497C2 (enExample)
TW (1) TW448172B (enExample)
UA (1) UA61906C2 (enExample)
WO (1) WO1997032846A1 (enExample)
ZA (1) ZA971902B (enExample)

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US5932579A (en) * 1996-06-18 1999-08-03 Affymax Technologies N.V. Collagenase-1 and stromelysin-1 inhibitors, pharmaceutical compositions comprising same and methods of their use
WO1997048688A1 (en) * 1996-06-21 1997-12-24 Pharmacia & Upjohn Company Thiadiazole amide mmp inhibitors
ATE289590T1 (de) * 1996-09-27 2005-03-15 Upjohn Co Beta-sulfonyl-hydroxamsäuren als matrix- metalloproteinaseinhibitoren
GB9702088D0 (en) 1997-01-31 1997-03-19 Pharmacia & Upjohn Spa Matrix metalloproteinase inhibitors
US6362183B1 (en) 1997-03-04 2002-03-26 G. D. Searle & Company Aromatic sulfonyl alpha-hydroxy hydroxamic acid compounds
US6566373B2 (en) 1997-05-06 2003-05-20 Smithkline Beecham Corporation Protease inhibitors
AR013079A1 (es) * 1997-05-06 2000-12-13 Smithkline Beecham Corp Derivados sustituidos de tetrahidrofurano-3-onas, de tetrahidropirano-3- onas y tetrahidrotiofen-3-onas, un procedimiento para su preparacion unacomposicion farmaceutica de un medicamento util como inhibidores de proteasas e intermediarios
US5883131A (en) * 1997-07-09 1999-03-16 Pfizer Inc. Cyclic sulfone derivatives
WO1999006340A2 (en) 1997-07-31 1999-02-11 The Procter & Gamble Company Sulfonylamino substituted hydroxamic acid derivatives as metalloprotease inhibitors
DE19741235A1 (de) * 1997-09-18 1999-03-25 Hoechst Marion Roussel De Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
ZA988967B (en) * 1997-10-03 2000-04-03 Du Pont Pharm Co Lactam metalloprotease inhibitors.
US6403632B1 (en) 2000-03-01 2002-06-11 Bristol Myers Squibb Pharma Co Lactam metalloprotease inhibitors
EP1024134A4 (en) * 1997-10-09 2003-05-14 Ono Pharmaceutical Co DERIVATIVES OF AMINOBUTANIC ACID
DE69915004T2 (de) * 1998-11-05 2004-09-09 Pfizer Products Inc., Groton 5-Oxo-pyrrolidine-2-Carbonsäure-Hydroxamidderivate
GB9825988D0 (en) * 1998-11-27 1999-01-20 Pfizer Ltd Indole derivatives
US20040122011A1 (en) * 1998-12-23 2004-06-24 Pharmacia Corporation Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy
SK12452001A3 (sk) 1999-03-03 2002-04-04 The Procter & Gamble Company Zlúčenina vytvárajúca inhibítor metaloproteinázy, farmaceutický prostriedok, spôsob prípravy liečiva a liečivo
WO2000051993A2 (en) 1999-03-03 2000-09-08 The Procter & Gamble Company Dihetero-substituted metalloprotease inhibitors
EP1165546A2 (en) * 1999-04-02 2002-01-02 Du Pont Pharmaceuticals Company Novel lactam inhibitors of matrix metalloproteinases, tnf-alpha, and aggrecanase
US6797820B2 (en) 1999-12-17 2004-09-28 Vicuron Pharmaceuticals Inc. Succinate compounds, compositions and methods of use and preparation
AU2002230385A1 (en) * 2000-09-25 2002-04-15 Questcor Pharmaceuticals, Inc. Peptide deformylase inhibitors
EP1355901A2 (en) 2001-01-11 2003-10-29 Bristol-Myers Squibb Pharma Company 1,1-DISUBSTITUTED CYCLIC INHIBITORS OF MATRIX METALLOPROTEASE AND TNF-$g(a)
CA2434044A1 (en) 2001-01-11 2002-07-18 Bristol-Myers Squibb Pharma Company 1,2-disubstituted cyclic inhibitors of matrix metallorproteases and tnf-alpha
DE60207384T2 (de) * 2001-03-01 2006-08-03 Smithkline Beecham Corp. Peptid-deformylase-hemmer
JP4314340B2 (ja) * 2001-06-15 2009-08-12 ヴィキュロン ファーマシューティカルズ インコーポレイテッド ピロリジン二環性化合物
AR036053A1 (es) 2001-06-15 2004-08-04 Versicor Inc Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas
PE20030701A1 (es) 2001-12-20 2003-08-21 Schering Corp Compuestos para el tratamiento de trastornos inflamatorios
TWI294778B (en) * 2002-03-13 2008-03-21 Smithkline Beecham Corp Peptide deformylase inhibitors
US7622117B2 (en) * 2002-04-17 2009-11-24 Dynamis Therapeutics, Inc. 3-deoxyglucosone and skin
PL374117A1 (en) * 2002-05-29 2005-10-03 Merck & Co, Inc. Compounds useful in the treatment of anthrax and inhibiting lethal factor
US20050176686A1 (en) * 2002-07-23 2005-08-11 4Sc Ag Novel compounds as histone deacetylase inhibitors
EP1626961B1 (en) * 2003-05-17 2011-11-02 Korea Research Institute of Bioscience and Biotechnology Novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same
US7122560B2 (en) 2003-06-18 2006-10-17 Bristol-Myers Squibb Company Lactam derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme
EP1663201A4 (en) * 2003-07-15 2009-10-28 Korea Res Inst Of Bioscience USE OF NOVEL 2-OXO-HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
KR101070036B1 (ko) * 2003-07-23 2011-10-04 노르딕 바이오사이언스 에이/에스 골관절염에 대한 칼시토닌의 용도
CN1950354A (zh) * 2004-05-11 2007-04-18 默克公司 N-磺酰化-氨基酸衍生物的制备方法
US20100003276A1 (en) * 2004-12-07 2010-01-07 Hermes Jeffery D Methods for treating anthrax and inhibiting lethal factor
DE102004060229A1 (de) * 2004-12-15 2006-06-29 Sanofi-Aventis Deutschland Gmbh Neue zyklische Harnstoffe als Inhibitoren von Metallproteasen
JP2008528624A (ja) * 2005-01-28 2008-07-31 アイアールエム・リミテッド・ライアビリティ・カンパニー フェニル置換ピロリドン
GB0811643D0 (en) 2008-06-25 2008-07-30 Cancer Rec Tech Ltd New therapeutic agents
FR2947268B1 (fr) * 2009-06-30 2011-08-26 Galderma Res & Dev Nouveaux composes benzene-sulfonamides, leur procede de synthese et leur utilisation en medecine ainsi qu'en cosmetique
US9738604B2 (en) 2010-09-03 2017-08-22 Duke University Ethynylbenzene derivatives
US20140081017A1 (en) * 2012-09-14 2014-03-20 Methylgene Inc. Histone Deacetylase Inhibitors for Enhancing Activity of Antifungal Agents
WO2015024011A2 (en) 2013-08-16 2015-02-19 Duke University Antibacterial compounds
AU2014306451B2 (en) 2013-08-16 2019-01-17 Duke University Substituted hydroxamic acid compounds
US9908851B2 (en) 2013-08-16 2018-03-06 Duke University 2-piperidinyl substituted N,3-dihydroxybutanamides
GB201517216D0 (en) 2015-09-29 2015-11-11 Cancer Res Technology Ltd And Astex Therapeutics Ltd Pharmaceutical compounds
GB201517217D0 (en) 2015-09-29 2015-11-11 Astex Therapeutics Ltd And Cancer Res Technology Ltd Pharmaceutical compounds
GB201704965D0 (en) 2017-03-28 2017-05-10 Astex Therapeutics Ltd Pharmaceutical compounds
GB201704966D0 (en) 2017-03-28 2017-05-10 Astex Therapeutics Ltd Pharmaceutical compounds

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US1360583A (en) * 1918-02-18 1920-11-30 Great Lakes Dredge And Dock Co Car-dumper
EP0042100A1 (de) * 1980-06-13 1981-12-23 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Pyrazolopyridazin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung, sowie diese enthaltende Arzneimittel
DE3420193A1 (de) * 1984-05-30 1985-12-05 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel
AU4267293A (en) * 1992-05-01 1993-11-29 British Biotech Pharmaceuticals Limited Use of MMP inhibitors
US5318964A (en) * 1992-06-11 1994-06-07 Hoffmann-La Roche Inc. Hydroxamic derivatives and pharmaceutical compositions
ATE195117T1 (de) * 1993-03-31 2000-08-15 Searle & Co 1-amdinophenyl-pyrrolidone/piperidinone als blutblättchen-aggregations inhibitoren
EP0712390B1 (en) * 1993-08-02 1998-12-09 Celltech Therapeutics Limited Succinamide derivatives, processes for their preparation and their use as gelatinase and collagenase inhibitors
GB9320660D0 (en) * 1993-10-07 1993-11-24 British Bio Technology Inhibition of cytokine production
US5403952A (en) * 1993-10-08 1995-04-04 Merck & Co., Inc. Substituted cyclic derivatives as novel antidegenerative agents

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