JP2000344715A - Production of asymmetric carbonic ester - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a method for producing an asymmetric carbonic ester with a suppressed activity of a catalyst even when used for a long period in the method for producing the asymmetric carbonic ester using the heterogeneous catalyst. SOLUTION: This method for producing an asymmetric carbonic ester comprises carrying out a disproportionating transesterification between two kinds of symmetric carbonic esters in the presence of water at 100-10,000 wt.ppm expressed in terms of concentration in a raw material together with a heterogeneous catalyst when producing the asymmetric carbonic ester by the disproportionating transesterification. Further, the disproportionating transesterification is a reaction for converting dimethyl carbonate and diethyl carbonate into ethyl methyl carbonate.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to a method for producing an asymmetric carbonate, and more particularly to a method for producing an asymmetric carbonate by a disproportionated transesterification reaction between two symmetric carbonates. The asymmetric carbonate ester is useful as a solvent or various organic synthesis reagents, and particularly useful as a solvent for a battery using a non-aqueous electrolyte such as a lithium ion battery or for a capacitor.

[0002]

2. Description of the Related Art Conventionally, as one method for producing an asymmetric carbonate ester using a transesterification catalyst, a disproportionated transesterification reaction between two kinds of symmetric carbonates is known. In order to bring the transesterification into an equilibrium state, the use of a transesterification catalyst is indispensable. For example, an alkali metal alcoholate catalyst (Japanese Patent Laid-Open No.
No. 811), an oxide of a group III rare earth element (Japanese Unexamined Patent Publication No.
-328453). These transesterification catalysts are classified into homogeneous catalysts and heterogeneous catalysts. In particular, heterogeneous catalysts require a large amount of catalyst and high temperature because they are less active than homogeneous catalysts, but since they themselves are insoluble in the reaction solution, it is difficult to separate the catalyst from the reaction solution. Easy and industrially preferred.

[0003] In an industrial-scale production method, how to suppress a decrease in the activity of a catalyst is important.
In the case of a fixed-bed liquid-phase flow reaction, since a heterogeneous catalyst is used in a state in which a large amount of the heterogeneous catalyst is filled in the reactor in advance, it is particularly important to suppress the decrease in the activity of the catalyst.

[0004]

SUMMARY OF THE INVENTION An object of the present invention is to provide a method for producing an asymmetric carbonate ester using a heterogeneous catalyst. Is to provide.

[0005]

Means for Solving the Problems The present inventors have made various studies, and as a result, obtained the knowledge that the above object can be easily achieved by the presence of a specific substance in the reaction system. The invention has been completed.

That is, the gist of the present invention is to produce an asymmetric carbonate by a disproportionated transesterification reaction between two symmetric carbonates, and to have a concentration in a raw material of 100 to 10,000 weight with a heterogeneous catalyst. The present invention resides in a method for producing an asymmetric carbonate ester, characterized in that the above reaction is carried out in the presence of water of at least ppm.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, the present invention will be described in detail.
In the present invention, the disproportionation reaction between the two types of symmetric carbonates proceeds as shown in the following reaction formula (1), and the desired asymmetric carbonate is formed.

[0008]

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In the formula (1), R ¹ and R ² each represent a different alkyl group or a cycloalkyl group.
The number of carbon atoms of the alkyl group or cycloalkyl group is not particularly limited, but is usually 1 to 12, preferably 1 to 6. Examples of the linear alkyl group include a methyl group, an ethyl group, a propyl group, a butyl group, a pentyl group, a hexyl group, a heptyl group, an octyl group, and a dodecyl group. Examples of the branched alkyl group include isopropyl, isobutyl, sec-butyl, tert-butyl, isoamyl, tert-amyl, neopentyl,
Examples include an isohexyl group, a sec-hexyl group, and a tert-hexyl group. Examples of the cycloalkyl group include a cyclopropyl group, a cyclobutyl group, a cyclopentyl group, a cyclohexyl group, a cycloheptyl group, a cyclooctyl group, a cyclododecyl group, and a norbornyl group.

Examples of the symmetric carbonate as a raw material include dimethyl carbonate (DMC), diethyl carbonate (DEC), dipropyl carbonate, dibutyl carbonate, dicyclohexyl carbonate and the like. Specific examples of the target asymmetric carbonic acid ester include ethyl methyl carbonate (EMC), methyl propyl carbonate, ethyl propyl carbonate, butyl methyl carbonate, butyl ethyl carbonate,
Butyl propyl carbonate, cyclohexyl methyl carbonate and the like. Note that the type of raw material is determined by the target, and when the target is EMC, D
MC and DEC are used.

The molar ratio of the two kinds of symmetric carbonates as starting materials is not particularly limited, but it is usually preferable to use them in substantially equimolar from the viewpoint of increasing the yield of the target asymmetric carbonate. However, one of the raw materials may be used in excess, and in this case, the molar ratio is preferably selected from the range of 1: 1 to 1:20.

The reaction is carried out in an atmosphere of an inert gas such as nitrogen. The reaction temperature is generally 0-300 ° C., preferably 5
It is selected from the range of 0 to 200 ° C. The reaction pressure is generally selected from the range of 0 to 5 MPa, preferably 0 to 1 MPa. The reaction system may be a batch system or a flow system, but the flow system is industrially advantageous because the raw material can be continuously processed in large quantities and the catalyst can be repeatedly used for a long time. In particular, a fixed bed liquid phase flow reaction is advantageous. The liquid hourly space velocity (LHSV) for the catalyst at this time is generally selected from the range of 0.05 to 50 / hr, preferably 0.1 to 10 / hr.

Further, by allowing the reaction to proceed in the liquid phase, the role of the solvent can be imposed on the raw material itself, so that the use of another solvent can be omitted. From the viewpoint of ease of post-treatment, it is preferable not to use another solvent. The reaction solution is separated into two kinds of symmetric carbonates as raw materials and an asymmetric carbonate as a reaction product by a known distillation method such as atmospheric distillation, reduced pressure distillation, and pressure distillation. As the order of the boiling points, for example, since the symmetric ester of one raw material, the asymmetric carbonate ester of the target, and the symmetric carbonate of the other raw material are distilled in this order, the target is desired as the second fraction of the distillation. Can be obtained. Here, the chain carbonate having a high boiling point among the raw materials may be distilled off, or may be left in the still and recycled for the reaction.

In the present invention, a conventionally known heterogeneous catalyst can be used without limitation. A catalyst described in JP-A-9-328453, that is, a catalyst containing an oxide of a group III rare earth element as an active ingredient is recommended. Specific examples of Group III rare earth elements include S
c, Y, lanthanide group elements (La, Ce, Pr, Nd,
Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, T
m, Yb, Lu), actinide group elements (Ac, Th, P
a, U) and the like.

The most important feature of the present invention is that, in order to suppress a decrease in the activity of the heterogeneous catalyst during long-term use, the concentration in the raw material together with the heterogeneous catalyst is 100 to 1000 parts per weight (pp).
m in the presence of water.

The mode in which the catalytic activity gradually decreases is as follows.
For example, when the catalyst itself loses its catalytic activity due to a chemical change due to the influence of the raw material or impurities contained in the raw material, the catalytic activity does not work effectively because the surface of the catalyst is covered by heavy substances by-produced in the reaction In such a case, the catalyst itself may be lost due to physical changes such as abrasion and crushing. The effect of water coexisting in the reaction system is not clear, but in any case, the water maintains the appropriate transesterification capacity required for the disproportionation reaction on the catalyst surface.

The amount of water to be present in the reaction system must be 100 to 10,000 ppm by weight in the raw material. When the amount of water is less than the above range, the effect of suppressing the decrease in the activity of the catalyst is not sufficiently exhibited, and when the amount of water is more than the above range, the asymmetric chain carbonate and water cause a side reaction to produce alcohol. Therefore, the yield of the target asymmetric carbonic acid ester decreases, and the loss in the purification step increases. The concentration of water in the raw material is preferably 200 to
It is in the range of 5,000 ppm by weight.

The method for allowing water to be present in the reaction system is not particularly limited. However, when an industrially advantageous fixed bed liquid phase flow reaction is employed, a method of adding water to the reaction system together with the raw materials is usually employed. . That is, as raw materials,
Two symmetric carbonates containing 000 ppm by weight of water are used. In any case, the addition of water to the reaction system may be performed in a pulsed manner so that the water concentration is within the above range on average.

[0019]

EXAMPLES Hereinafter, the present invention will be described in more detail with reference to examples, but the present invention is not limited to the following examples unless it exceeds the gist of the present invention.

Raw material production example 1: Commercially available industrial grades of dimethyl carbonate (DMC) and diethyl carbonate (DEC) were used, respectively, and distilled at a reflux ratio of 5 using a distillation column having 20 theoretical stages, and 10 to the charged amount. % Was removed as the initial fraction, and the next 80% by weight fraction was recovered as product. When the water content in the obtained DMC and DEC was measured by a Karl Fischer moisture meter, it was 20 ppm by weight or less. The DMC and DEC were mixed at a molar ratio of 1: 1 to obtain a raw material (1) having a water concentration of 15 ppm by weight.

Raw material production examples 2 to 7: Water was added to raw material (1) to prepare raw material (2) having a water concentration of 200 ppm by weight. Similarly, a raw material (3) having a moisture concentration of 300 ppm by weight, a raw material (4) of 500 ppm by weight, a raw material (5) of 1000 ppm by weight, a raw material (6) of 2000 ppm by weight, and a raw material (7) of 5000 ppm by weight Was adjusted.

Catalyst Production Example: Yttrium nitrate hexahydrate 3
2.3 kg (84.3 mol) of cobalt nitrate hexahydrate 2
4.5 kg (84.2 mol) was dissolved in 168 liters of pure water, and 550 kg of a 12% by weight aqueous solution of ammonium bicarbonate that had been previously charged and dissolved in an 800 liter stirring tank.
The resulting solution was dropped over about 4 hours to obtain a slurry containing a precipitate. This slurry was filtered with a filter press, washed with pure water, and then dried at 120 ° C. for 12 hours using a hot air drier to obtain 24.5 kg of a catalyst precursor.

Next, 44 parts by weight of water was added to 100 parts by weight of the catalyst precursor, 5 parts by weight of methylcellulose and 10 parts by weight of Avicel were added as molding aids, and the mixture was heated and kneaded to form a slurry. A cylindrical product having a diameter of 4 mm was formed by an extrusion molding method. Extrudability was good. The column was dried at 120 ° C. overnight, followed by 60
The catalyst was calcined at a temperature of 0 ° C. for 3 hours to obtain a catalyst having a diameter of about 3 mm. No abnormalities in appearance such as breakage or cracking were observed in the catalyst. The metal atomic ratio of the catalyst was 1: 1 with yttrium: cobalt.

Example 1 35.0 g of a catalyst was charged into a jacketed tubular reactor having an inner diameter of 17 mm and a length of 800 mm, and the raw material (2) (water concentration: 200 ppm by weight) was passed through a metering pump. LHSV2 at 140 ° C. while applying a back pressure of 0.9 MPa
(100 ml / hr). After 50 hours, the reaction solution was analyzed by gas chromatography. As a result, the composition of the reaction solution was 21.7% by weight of DMC, 49.5% by weight of ethyl methyl carbonate (EMC), and 28.5% by weight of DEC. This corresponds to an EMC yield of 49.5%.
The EMC generation rate at this time was 1.41 g per 1 g of the catalyst.
/ Hr. After this, the reaction is continued under the same conditions,
EMC yield per reaction time and EM / g catalyst
Table 1 shows the C generation rate.

[0025]

[Table 1]

Comparative Example 1 In Example 1, the raw material (1) (water concentration 15 wt.
The reaction was carried out under the same conditions as in Example 1 except that m) was used. The reaction solution after 42 hours was analyzed by gas chromatography.
The composition of the reaction solution was 21.5% by weight of DMC, 49.7% by weight of ethyl methyl carbonate (EMC), and DEC28.
It was 4% by weight. This is 49.7% as an EMC yield.
Is equivalent to The EMC generation rate at this time was 1.42 g / hr per 1 g of the catalyst. Thereafter, the reaction was continued under the same conditions.
Table 2 shows the EMC generation rate per unit. As is clear from Table 2, it can be seen that the yield and generation rate of EMC decrease with the reaction time.

[0027]

[Table 2]

Example 2 The reaction was carried out in the same manner as in Comparative Example 1 except that the raw material (1) was changed to the raw material (2). Gas chromatographic analysis of the reaction mixture 50 hours after changing the raw materials revealed that the composition of the reaction mixture was DMC2.
2.1% by weight, ethyl methyl carbonate (EMC) 4
8.5% by weight and DEC 29.1% by weight. This corresponds to an EMC yield of 48.5%. E at this time
The MC generation rate was 1.39 g / hr / g of catalyst. That is, the catalyst performance lowered in Comparative Example 1 was recovered. Thereafter, the reaction was continued under the same conditions. Table 3 shows the EMC yield and the EMC generation rate per 1 g of the catalyst for each reaction elapsed time.

[0029]

[Table 3]

Examples 3 to 7 The reaction was carried out under the same conditions as in Example 1 except that the raw materials (3) to (7) were used. The yield of EMC for a given reaction elapsed time and the EM / g of catalyst
Table 4 shows the C generation rate.

[0031]

[Table 4]

[0032]

According to the present invention described above, there is provided a method for producing an asymmetric carbonate in which a decrease in the activity of a catalyst is suppressed even after a long period of use, and the industrial value of the present invention is remarkable. It is.

Claims (2)

[Claims] In producing an asymmetric carbonate by disproportionation transesterification between two symmetric carbonates, the concentration in a raw material together with a heterogeneous catalyst is from 100 to 100.
A process for producing an asymmetric carbonic acid ester, wherein the above reaction is carried out in the presence of 10,000 ppm by weight of water. 2. The production method according to claim 1, wherein the disproportionated transesterification reaction is a reaction from dimethyl carbonate and diethyl carbonate to ethyl methyl carbonate.