JP2000204079A5 - - Google Patents

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Publication number
JP2000204079A5
JP2000204079A5 JP1999053551A JP5355199A JP2000204079A5 JP 2000204079 A5 JP2000204079 A5 JP 2000204079A5 JP 1999053551 A JP1999053551 A JP 1999053551A JP 5355199 A JP5355199 A JP 5355199A JP 2000204079 A5 JP2000204079 A5 JP 2000204079A5
Authority
JP
Japan
Prior art keywords
alkyl
phenyl
pyridyl
cycloalkyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1999053551A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000204079A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2000204079A publication Critical patent/JP2000204079A/ja
Publication of JP2000204079A5 publication Critical patent/JP2000204079A5/ja
Withdrawn legal-status Critical Current

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JP11053551A 1999-01-13 1999-03-02 ジアリ―ルアミン Withdrawn JP2000204079A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11587399P 1999-01-13 1999-01-13
US115873 2005-04-27

Publications (2)

Publication Number Publication Date
JP2000204079A JP2000204079A (ja) 2000-07-25
JP2000204079A5 true JP2000204079A5 (https=) 2006-04-27

Family

ID=22363895

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11053551A Withdrawn JP2000204079A (ja) 1999-01-13 1999-03-02 ジアリ―ルアミン

Country Status (2)

Country Link
JP (1) JP2000204079A (https=)
ZA (1) ZA200105224B (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2355470C (en) * 1999-01-13 2008-09-30 Warner-Lambert Company Benzoheterocycles and their use as mek inhibitors
CA2532067C (en) * 2003-07-24 2010-12-21 Stephen Douglas Barrett N-methyle-substituted benzamidazoles
US7144907B2 (en) * 2003-09-03 2006-12-05 Array Biopharma Inc. Heterocyclic inhibitors of MEK and methods of use thereof
ES2376771T3 (es) * 2006-08-21 2012-03-16 Genentech, Inc. Compuestos aza-benzofuranilo y métodos de utilización
ES2528797T3 (es) * 2006-08-21 2015-02-12 Genentech, Inc. Compuestos de aza-benzotiofenilo y métodos de uso
EP2370568B1 (en) 2008-12-10 2017-07-19 Dana-Farber Cancer Institute, Inc. Mek mutations conferring resistance to mek inhibitors
EP3028699B1 (en) 2010-02-25 2018-03-21 Dana-Farber Cancer Institute, Inc. Braf mutations conferring resistance to braf inhibitors
CN103038364A (zh) 2010-03-09 2013-04-10 达纳－法伯癌症研究所公司 诊断和治疗具有或发展对于第一种癌症治疗的抗性的患者中的癌症的方法
CN103204827B (zh) * 2012-01-17 2014-12-03 上海科州药物研发有限公司 作为蛋白激酶抑制剂的苯并噻二唑化合物及其制备方法和用途
US20150141470A1 (en) 2012-05-08 2015-05-21 The Broad Institute, Inc. Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037881A1 (en) * 1997-02-28 1998-09-03 Warner Lambert Company Method of treating or preventing septic shock by administering a mek inhibitor

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