JP2000204079A5 - - Google Patents

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Publication number
JP2000204079A5
JP2000204079A5 JP1999053551A JP5355199A JP2000204079A5 JP 2000204079 A5 JP2000204079 A5 JP 2000204079A5 JP 1999053551 A JP1999053551 A JP 1999053551A JP 5355199 A JP5355199 A JP 5355199A JP 2000204079 A5 JP2000204079 A5 JP 2000204079A5
Authority
JP
Japan
Prior art keywords
alkyl
phenyl
pyridyl
cycloalkyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1999053551A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000204079A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2000204079A publication Critical patent/JP2000204079A/ja
Publication of JP2000204079A5 publication Critical patent/JP2000204079A5/ja
Withdrawn legal-status Critical Current

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JP11053551A 1999-01-13 1999-03-02 ジアリ―ルアミン Withdrawn JP2000204079A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11587399P 1999-01-13 1999-01-13
US115873 2005-04-27

Publications (2)

Publication Number Publication Date
JP2000204079A JP2000204079A (ja) 2000-07-25
JP2000204079A5 true JP2000204079A5 (https=) 2006-04-27

Family

ID=22363895

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11053551A Withdrawn JP2000204079A (ja) 1999-01-13 1999-03-02 ジアリ―ルアミン

Country Status (2)

Country Link
JP (1) JP2000204079A (https=)
ZA (1) ZA200105224B (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL144214A0 (en) * 1999-01-13 2002-05-23 Warner Lambert Co Benzoheterocycles and their use as mek inhibitors
ES2331246T3 (es) * 2003-07-24 2009-12-28 Warner-Lambert Company Llc Derivados de benzamidazol como inhibidores del mek.
US7144907B2 (en) * 2003-09-03 2006-12-05 Array Biopharma Inc. Heterocyclic inhibitors of MEK and methods of use thereof
ES2528797T3 (es) * 2006-08-21 2015-02-12 Genentech, Inc. Compuestos de aza-benzotiofenilo y métodos de uso
AU2007286808B2 (en) * 2006-08-21 2012-12-06 Genentech, Inc. Aza-benzofuranyl compounds and methods of use
WO2010068738A1 (en) 2008-12-10 2010-06-17 Dana-Farber Cancer Institute, Inc. Mek mutations conferring resistance to mek inhibitors
ES2576061T3 (es) 2010-02-25 2016-07-05 Dana-Farber Cancer Institute, Inc. Mutaciones de BRAF que confieren resistencia a inhibidores de BRAF
BR112012022801B8 (pt) 2010-03-09 2019-10-29 Dana Farber Cancer Inst Inc método de identificar um indivíduo que tem câncer que é provável beneficiar-se do tratamento com uma terapia de combinação com um inibidor de raf e um segundo inibidor e uso de um inibidor de raf e um segundo inibidor para a fabricação de um medicamento para tratar câncer
CN103204825B (zh) * 2012-01-17 2015-03-04 上海科州药物研发有限公司 作为蛋白激酶抑制剂的苯并噻唑化合物及其制备方法和用途
US20150141470A1 (en) 2012-05-08 2015-05-21 The Broad Institute, Inc. Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5610398A (en) * 1997-02-28 1998-09-18 Warner-Lambert Company Method of treating or preventing septic shock by administering a mek inhibitor

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