JP2000159628A - Granule-formulated cosmetic composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain the subject cosmetic composition safe to the skin and affording moderate feeling of massage and stimulation by the aid of the granules per se formulated therein. SOLUTION: This cosmetic composition is obtained by formulating at least one kind of granules selected from those of organic polymers, fat-and-oil, waxes, mineral oils, inorganic matter and plants, or granules prepared by granulating water-insoluble primary particles with a binder; wherein the granules have a roundness factor of 0.98-0.40, form factor of 0.98-0.50, and particle size of 50-2,000 μm. Being formulated with such granules of specific shape and particle size, this cosmetic composition affords soft touch to the skin and comfortable feeling of stimulation as well, also having sufficient cleansing ability.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic composition containing useful granules, and more particularly, to at least one selected from organic polymers, oils and fats, waxes, mineral oils, inorganic substances, and plants. Or the granules obtained by granulating a water-insoluble primary particle with a binder have a circularity coefficient of 0.98 to 0.1.
40, the shape factor 2 is in the range of 0.98 to 0.50 and the particle size is in the range of 50 to 2000 μm. By blending the granules, the granules themselves have an appropriate massage effect and the washing effect is also high. The present invention relates to an application to a cosmetic composition.

[0002] The field of use is effective, for example, in cleaning agents, massage agents, cleansing agents, etc., but also in various other external preparations (including preparations used for animals). Specifically, ampules, capsules, pills, tablets, powders, granules, solids, liquids, pastes, O / W emulsions, W / O emulsions, gels, or foams 1) Pharmaceuticals, 2) Quasi-drugs,
3) Topical or systemic skin cosmetics (for example, basic cosmetics such as lotions, emulsions, creams, ointments, lotions, oils, packs, facial cleansers and skin cleansers, depilatory agents, depilatory agents, mustaches) Shave treatment fee, after-shave lotion, pre-show lotion, shaving cream, etc.),
4) Pharmaceutical and / or cosmetic preparations applied to the scalp / hair (eg, shampoos, rinses, treatments, permanent solutions, hair dyes, hair styling agents, hair tonics, hair growth / hair restoration, etc.), 5 ) Bath agents used by throwing them into bath water, 6) Others, such as liquid odor and deodorant inhibitors, sanitary articles, sanitary cotton, wet tissues, etc.

[0003]

2. Description of the Related Art When examining granules to be blended in detergents and cosmetics in which granules are blended so far, it is apparent that the granules can be classified into several types according to their materials and characteristics. That is, (1) For example, a crushed plant seed shell or a hydrocarbon-based polymer material such as polyethylene or polystyrene having a particle size of 50 μm to
It is of the order of 1000μm, but its size does not change when used. (2) Several [mu] m to 20 [mu] m using a water-soluble binder or fat or oil as a binder.
A typical powder is a powder having a size of about 200 μm to 2000 μm, which gradually decreases and disappears during use.

[0004]

However, these have the following inconveniences and disadvantages in production or use, for example, a feeling of contact of particles with the skin or eyes, and a massage-like effect. The effect and dirt removal effect (cleaning effect) are also high, but both are too strong,
Excessive irritation during use caused damage to the skin and skin due to the shape of the particles due to the shape of the particles. On the other hand, when the granule shape is close to a spherical or a true sphere, the scrubbing function such as a massage effect and a washing effect is conversely small, and even if the granules have the same hardness, a difference occurs in the scrubbing function depending on the granule shape.

[0005]

Accordingly, the present inventors have:
In order to develop a new type of granule which does not have these various disadvantages and disadvantages, intensive studies have been made. That is, particles of a defined type can be blended as granules in a cosmetic composition, and have a suitable massage (promoting blood circulation) without scars, irritation and discomfort to the skin and eyes. ) By providing a safe and effective product that has a cleaning effect and a more comfortable use
The present invention has been completed.

That is, one or more particles selected from organic polymers, fats and oils, waxes, mineral oils, inorganic substances, and plants, or granules obtained by granulating a water-insoluble primary particle with a binder,
The present invention provides a cosmetic composition containing a granule having a circularity coefficient of 0.98 to 0.40, a shape coefficient of 0.98 to 0.50, and a particle size of 50 to 2000 μm.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION The particles that can be used in the present invention are shown below, but are not limited thereto. That is, granules obtained by granulating one or more particles selected from organic polymers, fats and oils, waxes, mineral oils, inorganic substances, plants, or water-insoluble primary particles using a binder.

[0008] Organic polymers include polyethylene, polystyrene, polyvinyl chloride, polyamide, polyester, polypropylene, polycarbonate, nylon powder,
Silicon powder, polyvinyldene fluoride, polyurethane, polysiloxane, cyclodextrin, acrylic resin,
Examples include phenolic resins, urea resins, melamine resins, crystalline cellulose, starch, xanthan gum, and organic polymer compounds of these derivatives.

The fats and oils include avocado oil, almond oil, fennel oil, perilla oil, olive oil, orange oil,
Orange ruffer oil, sesame oil, cocoa butter, chamomile oil,
Carrot oil, cucumber oil, tallow fatty acid, kuku nut oil, safflower oil, shea butter, soybean oil, camellia oil, corn oil, rapeseed oil, persic oil, castor oil, cottonseed oil, peanut oil, turtle oil, mink oil, egg yolk oil Cocoa butter, palm oil, palm kernel oil, mocro, coconut oil, beef tallow, lard, and hydrogenated products (hardened oil) of these fats and oils.

[0010] The waxes include beeswax, carnauba wax, whale wax, lanolin, liquid lanolin, reduced lanolin,
Examples include hard lanolin, candelilla wax, montan wax, shellac wax, rice wax, squalene, squalane, pristane, and the like.

Examples of the mineral oil include liquid paraffin, vaseline, paraffin, ozokeride, ceresin, and microcrystalline wax.

Examples of the inorganic substance powder include silica, hydrated silica, silicic anhydride, silicic acid, aluminum silicate, aluminum aluminum silicate, zirconium silicate, montmorillonite, hectorite, bentonite, zeolite,
Dicalcium phosphate, calcium carbonate, alumina, talc, titanium oxide, titanium dioxide, mica, mica, titanium mica, kaolin, redwood, gunjo, zinc oxide,
Zirconium oxide, iron oxide, yellow iron oxide, black iron oxide, chromium oxide, chromium hydroxide, carbon black, calamine,
Examples include inorganic minerals such as quartz, and inorganic salts such as calcium phosphate, calcium hydrogen phosphate, calcium carbonate, magnesium carbonate, and sulfur.

Plants include apricot inner rind / seed / core coconut seed, almond pulp / seed, walnut inner rind / shell, birch trunk, peach inner pericarp / nucleus, sunflower seed, corn cob, yoquinin , Sunflower oil, jojoba oil, coconut oil pomace, watermelon seeds, pine nuts, chimp, shobu, peanuts, chamomile, bodaige, soybean, ginseng, wheat, pine nuts, pulp various plant shells (for example,
Cottonseed), silk, seaweed (red algae, green algae, brown algae) and the like.

[0014] The water-insoluble primary particles include inorganic powders such as silica, hydrated silica, silicic anhydride, silicic acid, aluminum silicate, aluminum agnesium silicate, zirconium silicate, montmorillonite, hectorite, bentonite. , Zeolite, dicalcium phosphate, calcium carbonate, alumina, talc, titanium oxide, titanium dioxide, mica, mica, mica titanium, kaolin, red iron,
Inorganic minerals such as gunjo, zinc oxide, zirconium oxide, iron oxide, yellow iron oxide, black iron oxide, chromium oxide, chromium hydroxide, carbon black, calamine, quartz, calcium phosphate, calcium hydrogen phosphate, calcium carbonate,
Inorganic salts such as magnesium carbonate and sulfur are listed.

Similarly, organic polymer powders include polyethylene, polystyrene, polyvinyl chloride, polyamide, polyester, polypropylene, polycarbonate, nylon powder, silicon powder, polyvinyldene fluoride,
Polyurethane, polysiloxane, cyclodextrin,
Acrylic resins, phenolic resins, urea resins, melamine resins, crystalline cellulose, starch, xanthan gum, and the like, and organic polymer compounds of these derivatives are listed.

As the binder, gum arabic, benzoin gum, dammar gum, guaiac oil, Irish moss, karaya gum, tragacanth gum, carob gum, quinseed, agar, casein, dextrin, gelatin,
Natural organic polymer compounds such as pectin, sodium pectate, starch, sodium alginate, carrageenan and xanthan gum. Also, polyvinylpyrrolidone, polyvinylpyrrolidone-vinyl acetate copolymer, polyethylene glycol, polyvinyl alcohol, polyvinyl methyl ether, sodium polyacrylate, carboxyvinyl polymer, polyethyleneimine and methylcellulose, ethylcellulose, acetylcellulose, nitrocellulose, vinyl acetate resin, Crystalline cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethyl cellulose, carboxymethyl cellulose sodium, hydroxypropyl methyl cellulose, hydroxypropyl methyl cellulose phthalate, cellulose acetate, phthalate, cellulose propionate phthalate, cellulose acetate maleate, polyvinyl alcohol phthalate, polyvinyl alcohol phthalate Len-acrylic acid copolymer, methyl acrylate-methacrylic acid copolymer, polymer with vinyl pyridine or alkyl vinyl pyridine and other vinyl monomers, cellulose acetate diethyl amino acetate, polyvinyl acetate diethyl amino acetate, polyvinyl amino acetal, dimethyl Amino methacrylate-methyl methacrylate copolymer. Semi-synthetic / synthetic polymer compounds such as acetate, vinyl pyridine or a copolymer of alkyl vinyl pyridine and acrylic acid, or a three-component copolymer with another vinyl monomer. In addition, inorganic compounds such as montmorillonite, kaolin, hydrated silica, aluminum magnesium silicate, calcium carbonate, hectorite and the like can be mentioned.

The production method is not particularly limited, but the granules of the present invention can be produced by a general method (fluidized bed granulation method, stirring granulation method, extrusion granulation method, submerged granulation method, Spray cooling, melt dispersion cooling, tumbling granulation, compression granulation, crushing granulation, spray drying granulation, liquid phase granulation, etc.) Has a circularity coefficient of 0.98 to 0.40 and a shape coefficient of 0.98 to 0.98.
Use of the range of 0.50, the adjustment of the granule shape,
Depending on the type of the granules (organic polymer, oils and fats, waxes, mineral oils, plants), the purpose of use, and the use, it can be arbitrarily adjusted using a sieve, a vertical granulator, or the like.

Further, one or more particles selected from the organic polymers, fats and oils, waxes, mineral oils, inorganic substances, and plants of the present invention, or granules obtained by granulating a water-insoluble primary particle with a binder. Has a particle size of 50 to 2000 μm, preferably 100 to 800 μm in the cosmetic composition.

The granules of the present invention can be used singly or in combination of two or more. The granules of the present invention usually vary slightly depending on the type of cosmetic composition and the expected degree of action. The content is preferably from 01 to 20% by weight or more (hereinafter, represented by%), preferably from 0.05 to 5%, and the compounding amount is 0.1%.
If it is less than 001%, the effect cannot be expected sufficiently.

The cosmetic composition containing the granules of the present invention comprises:
In addition to the above essential components, if necessary, within the range not impairing the effects of the present invention, arbitrarily select and use components and additives used in pharmaceuticals, quasi-drugs, cosmetics, and other preparations. Can be manufactured.

(1) Various fats and oils Avocado oil, almond oil, fennel oil, perilla oil,
Olive oil, orange oil, orange luffer oil, sesame oil,
Cocoa butter, chamomile oil, carrot oil, cucumber oil, tallow fatty acid, kukuinut oil, safflower oil, shea butter oil, soybean oil, camellia oil, corn oil, rapeseed oil, persic oil, castor oil, cottonseed oil, peanut oil, turtle oil , Mink oil, egg yolk oil, cocoa butter, palm oil, palm kernel oil, mocro, coconut oil, tallow, lard, hydrogenated products of these oils (hardened oil, etc.).

(2) Waxes Beeswax, carnauba wax, whale wax, lanolin, liquid lanolin, reduced lanolin, hard lanolin, candelilla wax,
Montan wax, shellac wax, rice wax, squalene, squalane, pristane, etc.

(3) Mineral oil Liquid paraffin, vaseline, paraffin, ozokeride, ceresin, microcrystalline wax and the like.

(4) Fatty acids Natural fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, 12-hydroxystearic acid, undecylenic acid, tall oil, lanolin fatty acid, isononanoic acid, caproic acid , 2-ethylbutanoic acid, isopentanoic acid, 2-methylpentanoic acid, 2
-Synthetic fatty acids such as ethylhexanoic acid and isopentanoic acid.

(5) Alcohols Ethanol, isopyropanol, lauryl alcohol,
Natural alcohols such as cetanol, stearyl alcohol, oleyl alcohol, lanolin alcohol, cholesterol, and phytosterol; and synthetic alcohols such as 2-hexyldecanol, isostearyl alcohol, and 2-octyldodecanol.

(6) Polyhydric alcohols Ethylene oxide, ethylene glycol, diethylene glycol, triethylene glycol, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, polyethylene glycol, propylene oxide, propylene glycol , Polypropylene glycol, 1,3-butylene glycol, glycerin, pentaerythritol, sorbitol, mannitol and the like.

(7) Esters Isopropyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, oleyl oleate, decyl oleate, octyl dodecyl myristate, hexyl decyl dimethyloctanoate, cetyl lactate, Myristyl lactate, diethyl phthalate, dibutyl phthalate, lanolin acetate, ethylene glycol monostearate, propylene glycol monostearate, propylene glycol dioleate, and the like.

(8) Metal soaps Aluminum stearate, magnesium stearate, zinc stearate, calcium stearate, zinc palmitate, magnesium myristate, zinc laurate, zinc undecylenate and the like.

(9) Gum, saccharides and water-soluble polymer compounds Arabic gum, benzoin gum, dammar gum, guaiac oil, Irish moss, karaya gum, tragacanth gum,
Carob gum, quinseed, agar, casein, lactose,
Fructose, sucrose and its esters, trehalose and its derivatives, dextrin, gelatin, pectin, starch, carrageenan, carboxymethyl chitin or hydroxyalkyl (C2-C4) to which alkylene (C2-C4) oxide such as ethylene oxide is added. ) Chitin or chitosan, low molecular weight chitin or chitosan, chitosan salt, sulfated chitin or chitosan, phosphorylated chitin or chitosan, alginic acid and its salts, hyaluronic acid and its salts, chondroitin sulfate and its salts, heparin, ethyl cellulose, methyl cellulose, carboxy Methylcellulose, carboxyethylcellulose, sodium carboxyethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, nitrocellulose, crystalline cellulose, Vinyl alcohol, polyvinyl methyl ether, polyvinyl pyrrolidone, polyvinyl methacrylate, polyacrylic acid salts, polyalkylene oxide or crosslinked polymer thereof such as polyethylene oxide or polypropylene oxide, carboxyvinyl polymers, such as polyethyleneimine.

(10) Surfactant Anionic surfactant (alkyl carboxylate, alkyl sulfonate, alkyl sulfate, alkyl phosphate), cationic surfactant (alkyl amine salt, alkyl quaternary ammonium salt) ), Amphoteric surfactant:
Carboxylic acid type amphoteric surfactant (amino type, betaine type), sulfate ester type amphoteric surfactant, sulfonic acid type amphoteric surfactant, phosphate type amphoteric surfactant, nonionic surfactant (ether type nonionic) Surfactants, ether ester type nonionic surfactants, ester type nonionic surfactants, block polymer type nonionic surfactants, nitrogen-containing nonionic surfactants), other surfactants (natural surfactants) , Derivatives of protein hydrolysates,
Polymer surfactant, surfactant containing titanium and silicon,
Fluorocarbon surfactants).

(11) Various vitamins Vitamin A group: retinol, retinal (vitamin A
1), dehydroretinal (vitamin A2), carotene, lycopene (provitamin A), vitamin B group: thiamine hydrochloride, thiamine sulfate (vitamin B1), riboflavin (vitamin B2), pyridoxine (vitamin B)
6), cyanocobalamin (vitamin B12), folic acids,
Nicotinic acids, pantothenic acids, biotins, choline,
Inositols, vitamin C group: ascorbic acid and its derivatives, vitamin D group: ergocalciferol (vitamin D2), cholecalciferol (vitamin D)
3), dihydrotaxerol, vitamin E group: tocopherol and its derivatives, ubiquinones, vitamin K
Group: phytonadione (vitamin K1), menaquinone (vitamin K2), menadione (vitamin K3), menadiol (vitamin K4), other essential fatty acids (vitamin F), carnitine, ferulic acid, γ-oryzanol, orotic acid, vitamin Ps (Rutin, eriocitrin, hesperidin), vitamin U, etc.

(12) Various amino acids Valine, leucine, isoleucine, threonine, methionine, phenylalanine, tryptophan, lysine, glycine, alanine, asparagine, glutamine, serine, cysteine, cystine, tyrosine, proline, hydroxyproline, aspartic acid, glutamic acid , Hydroxylysine, arginine, ornithine, histidine, and the like, and their sulfates, phosphates, nitrates, citrates, and amino acid derivatives such as pyrrolidone carboxylic acid.

(13) Various additives derived from plant or animal raw materials These are usually processed according to the type and form of the product to be added (for example, grinding, milling, washing, hydrolysis, Fermentation, purification, squeezing, extraction, fractionation, filtration, drying, pulverization, granulation, dissolution, sterilization, pH adjustment, deodorization, decolorization, etc. You can choose to serve.

The solvent to be used for the extraction may be selected in consideration of the purpose and type of the product to be provided, or the processing to be performed later, but usually, water or a water-soluble organic solvent (eg, ethanol) ,Propylene glycol,
1, selected from 1,3-butylene glycol)
It is desirable to use a species or a mixture of two or more species. However, when the content of the organic solvent is not preferable depending on the application, only water may be used, or ethanol which is easily removed after extraction may be used, and may be used alone or in an arbitrary mixed solution with water, Exploited extract may be used.

In addition, additives derived from plant or animal raw materials are
When applied to systemic or topical external preparations and cosmetics, including protection of skin and hair, moisturizing, improvement of feel and texture,
Gives flexibility, relieves irritation, relieves stress due to aroma, activates cells (prevents cell aging), suppresses inflammation, improves skin and hair quality, prevents and improves rough skin, hair growth, hair growth, hair loss prevention, gloss Application, cleaning effect, alleviation of fatigue, promotion of blood flow,
In addition to cosmetic effects such as a warm bath effect, effects such as flavoring, deodorizing, thickening, preserving, and buffering can be expected.

Specific plants (crude drugs) as raw materials include
For example, almond (Hen peach), eye (Aiba), blue oak
(Seifu Fuji), Aotsu Lafuji (Kibo Komi), Acacia, Akashoma (Akasho-ma), Akasugi Fruit, Akagrape, Akaminoki (Logwood), Akamegawiwa (Akabu Kashiwa), Akane
(Kanekane Akane), Ayajiou Jiou (Jihuang), Agi (Awei),
Akinire (Royu skin), Akebi (Kidori), Asa (Asako-jin), Malva Asagao or Asagao (Toshiboshi), Hydrangea (Hydrangea), Amacha (Amacha), Ashitaba (Asahi), Amana (Kojingi), Azuki (red azuki beans), acerola, asenyak
(Asenyaku), Anise, Abemaki fruit, Avocado, Ama, Amacha (sweet tea), Amachaworu, Amadokoro (Tamatake), Amigasa lily (Shellfish), Altea, Arnica, Aloe (luxe),
Aloe vera, angelica, apricot honganzu (almond jelly), ansokkou (benzuka), igakozorina (biliary head), rush (light heart grass), knotweed (tiger cane root), strawberry,
Fig (fructose) or its leaves, Ichihatsu (primary), Ichibi (Aoi-ko), Ichiyakusou (one medicinal herb), Ginkgo (Ginkgo leaves, Ginkgo), Itohimemegi (Enshi), Carob bean, Inuazuna (Teilexi), rice seed or The seed coat is seed coat, Inondo seed, Ibuki-kusou, nettle, ylang-ylang, iwa-tobacco (Iwatakechi), oolong tea, fennel
(Fengxiang), Ukiyagara (Mitsuryo), Uguisukagura fruit, Himeuikyo, Turmeric (Utsukin), Duckweed (Buoying), Usubasaishin Keirinsaishin (spicy), Usveniaoi,
Pterodactyla mushroom, Nepenthes (summer hay), Udo or Shishido (Kang, Independent, Tang Independent), Plum (Ume) or its pulp, Vladigashi, Uwaurushi (Kusacokomomo), Unshurikan (Chen skin), Estragon, Ezogoke (Ezo fivega) ), Echinashi (Echinacea vulgaris), Echinida, Enokitake (Enoki mushroom), Ebisugusa / Cassia tora (Keyoshiko), Elderberry fruit, Elemi, Eringy (pre-rotus Erinji), Endu (rice flower, soybean rice), ogi・ Kibanaoogi (Astragalus), Ouren (Organic),
Giant crows (caronine), giant clam (self-defense), giant psyllium (vegetative child, vegetative grass), great hazel (haruko), great okana okera (white aphid), great oyster shabushi fruit, great hawthorn hawthorn (Yamasato), great oyster (narukoyuri, Kagikurumabanarukoyuri), Sasanoyuki, Sasanoyuki, barley (barley), Ooishigusa (cereal grass),
Oguruma (turning over), Okra fruit, Panax ginseng and Caribbean ginseng (Ginseng), Hypericum perforatum, Hypericum perforatum, St. John's wort (Brother's cut grass), Odorikosou (intermittent), Onamimi (blue ears), Onigurumi, Oninoyagara・ Hatakata lily (Yuri), Ononis, Halibut (Rihayu), Ominaeshi (Loose), Dutch mustard (Crasson), Dutch jelly, Dutch honeybee, Olive (fruit, seed, leaf), Oregano, orange fruit or pericarp, Caykei Jio (ripe ground yellow), cacao seeds, oysters or leaves thereof (persimmon), kagi kazura (choto), cassia, casino fruit (kozumi), gajutsu (shazajutsu), kashiwa (basin tree, basin leaves), cascarilla, Cascara sagrada, kanikusa (kinsato), valerian (valer), birch or weeping birch (white birch), pumpkin, kapok seed, kahok Nshou (蜀椒),
Gama (bamboo), chamomile, roman chamomile, chamilia
(Weeds), camucam / camouflage, crow squirrel (gold melon), crow squirrel (midsummer), mussel, guarana seeds, karahoo (thick), karaya, karin (gourd), garcinia, kawataketake, kawaranadeshiko (stone bamboo), ezokawaranadeshiko ( Qumugi, Quumiko), Japanese mugwort (Inchinko), Kansui
(Sweet), licorice (licorice), cantaraasa, candelilla,
Kantou, Canna, Raspberry (Ezo strawberry, Dutch strawberry, Shrimp strawberry, Nawashiro strawberry, Maple strawberry, European strawberry), Kiwi fruit, Kikarasuuri
(Kuroro root), Kikyo (Kikyo, Kikyo root), Chrysanthemum (Chrysanthemum, Shima kaniku, Drosophila), Catalpa (Azumi), Rigid ridge (Yotei root), Pheasant (Kikomi), Kizuta, Kidachi aloe,
Peppermint, Kinna, Chinese linden (Shincona, Red linden), Yellowfin (Huangbashi), Gymnema sylvestre, Cabbage, Cabbage immature fruit, Cucumber, Gyoryu (Nishikawayanagi ・
Teriyaki), Kiraja saponaria, Kiraya, Kiran-sou (gold acne grass), kumquat fruit, betel, kinmizuki
(Sengaku grass), guava fruit, guayule, Quercus infectria (gallicia), cucumber nuts, wolfberry (mugi, gugi, gugi leaves, skeletal bark), cedar grass (Tenmen Fuyu), vine (kuzukon), camphor tree, gooseberry Fruits, gardenia, gardenia, black clover, kumazasa, black pine, horseradish, clara, bittersweet, cranberry fruit, chestnut or its skin, curculigo latifolia fruit, grapefruit, buckthorn, black crocodile (rescue) , Kurobana Hikiokoshi, Clove (cloves, cloves), Gumbinazuna (Sekimei, Sekimeishi), Kaigai (Ikutake, Ikutakeho),
Celosia (cow flower, rooster), bay laurel, kenashisarutoribara (Tsubukuryo, Yamakiko), gentian,
Gennoshoco (Old treasured grass), Koji / Tachibana / Obenimikan / Ponkan / Santara (Tachibana skin), Koushinbara (Monthly flower), Kouzuikka, Kozo fruit, Kocha (tea), Kouhone (river bone), Kohon (waramoto, Kara straw book), Koulyang, Cilantro fruit, Kou Ren (Kohren), Koganebana (Yellow Gon), Cowberry (Koshibachi), Coconut fruit, Goshyu (Gusyuyu), Goshoi strawberry (Ubonashi), Pepper (Hot pepper), Copaiba balsam, Coffee beans , Kobushi magnolia, burdock, burdock, burdock, sesame
(Sesame seeds), Sesame grass (Ginseng), Gomishi (Gomiko), Sanekazura Binankazura Matsubusa, Wheat (wheat), Rice
Rice bran (red bran, white bran), rice oil, cola, acuminata seeds,
Cola vera seeds, fenugreek fruit, colombo, conzlango, kelp, konjac, comfrey (finnari grass), sisal (sisalasa), saxima buttonpul (weird sen), cherry (oshima cherry, yamazakura, oyamazakura),
Leaf, flower, fruit, bark (cherry bark), cherry, pomegranate, sasa, sasanqua, sajiomodachi, sweet potato, sweet potato , Sugar beet, jujube jujube (acid jujube), saffron (banana safflower, western safflower), pomelo fruit, sabonso, salmonberry fruit, sarashinasho (masuma), salvia (sage), sawagikyo (yamachona), sawagurumi (yamakotomo) ), Sanshin ginseng (San carrot), Sanshuyu (sanshuyu), Sansho
(Sansho), Sandscon (Soybean root), Shea (Carite), Cyanoki fruit, Shiitake (Shitake mushroom), Shion (Shion), Dikitaris, Shikunshi (Kimiko), Perilla, Aodiso, Chirimendiso, Catamendiso (Perilla leaves, Perilla) ), Rosewood, linden, Chinese pine, Chinese forsythia (forsythia), shimeji (hinshimeji,
Shakashimeji, Hatakeshimeji, Oshiiroshimeji, Bunashimeji, Shirotamogitake),
Peony (Shakuyaku), Shajin (Shasan), Janohige (Bakumon winter), Juzudama, Palm fruit, Ginger (Ginger), Shobu (Iris, Iris root), Shozuku fruit, Shirakashi seed, Shirogoshi butterfly seed, White adzuki bean (chicken bone) Grass), Shirobanairis (Small iris), Shirobanatsuta flower, Shirominanten (Namitenmi), Cinchonasakusylbra, Jinkoge (Mizuka, Mizuka flower, Shencho flower), Cinnamon, Watermelon (watermelon), Honeysuckle (Golden flower, Shinobi) Sorrel (acid model), Swimberry fruit, Stevia, Strawberry fruit, Suzu Psycho (Long Xu), Japanese horsetail (Thorn thorn), Suberhiyu (Horse ken,
Kento), plum fruits, cones of Scots pine,
Larch, vegetation, walnuts,
Hawthorn, dandelion, horse chestnut (malonie), pear fruit, prunus officinalis, elderberry, yellowtail (juniper, morimatsu), northern yaw (milfoil), yellow pears, yellow pears Mint, mint, horseradish, horseradish, sekisho, zeniyaoi, hirohasenega, senega, seri, celery, senkyu, senkyu (river cucumber), sendan, senburi (drug), senna fruit or leaves,
Senninsou (great tate), souka (grass), buckwheat seeds, soybean potato, rhubarb (daisuki), radish, soybean, daidai (orange peel, kikomi), takatodai (daigei), takawarabi (gull),
Dark sweet cherry fruit, hollyhock, hollyhock (thyme, Hyakurika), hollyhock, tamarind seeds, onion, tamshiba (spicy), taro bark or its root bark, tanjin (dansin), dandelion (gakko British) or shirobana dandelion, moko dandelion, dammar , Cherry fruit, chigaya or its roots (chinese radish), ginseng carrots (bamboo ginseng),
Chicory, Korean ginseng (Gomiko), Chinese radish (Ohta), Korean lance (Wuyi), Korean ginseng
(Ginseng), Artemisia (Aiba), Choreimaitake
(Irei), Japanese Ginseng, Japanese chestnut (mushroom),
Camellia, camellia, clover (lacquer lacustrine), communis (duckweed), vines (red azuki), vines (red bean), vines (vegetables), vines (four-leaf ginseng), vines, deiko, teuchigurumi, duberry fruit, tengusa , Tencha (tencha), tendai yak (crowd medicine), toga (winter gourd),
Pepper (pepper), corn (toki), calendula (marigold), corn or corn hair (southern hair), horned rice mochi (female child), torindo (ryubiru),
Tokusa (pirate), Dokudami (jujutsu), Tokon (root), Toshishi, Mamedaoshi and Neashikazura, Eucommia (Tonaka, Tonakaha), Ash (Cowhide), Tomato, Tragant, Triacanthus seed, Tormentilla, Doronoki, Troroaoi, Nai Zeria berry fruit, yam yam (Yamayaku), nagi ramen (butcher bloom), naginata koju, nazuna, rapeseed, jujube, jujube (daijutsu), nanawaibara (gold sakurako), nameko, narko lily (yellow), peanut (peanut) , Nanten (Minami Tenmi), Nigaki (Maki),
Sagebrush (bitter mosaic), nutmegium, kei nikkei (cinnamon bark)
Fruits / flowers or foliage of Keishi (Chrysanthemum), Chinese chive (Niriko), Elderberry (bone-attached tree), Garlic (Gourd), Nurde (Golden), Leek, Nozami (Ohiji), Neubara (Yomi), Yarrow,
Japanese radish (maehu), wild rose, peach, palm, pineapple fruit, hibiscus (Bussouge, Furinbussuge, Roselle), Hakamauraboshi (bone crushing supplement), Hakusen (ringworm skin), Hakuruberry fruit, Hakobe (Horiko), Hashibami (Haruko) , Hasiridokoro (Roth root), Basil, Lotus (Lotus, Lotus, Lotus), Parsley (Netherland jelly), Naked mulberry, Batata, Hachiku Madake (Bamboo boiled), Patchouli, Mint (Lightly loaded, Lightly loaded leaves), Adlay (Yokinin) ), Hanasuge (chimbo), Banana, Hanamint, Hanabishi (Siturishi, Shisitsuri), Vanillabins, Papaya, Scotch (Rice koji), Habu grass, Paprika, Hamago and Mitsuba Hamago (Thornbrush) , Hamabishi (Satsuriko), Hamanas (Maikai flower), Hamabo fu (Hama windbreak), Hamamelis, Rose (rose), Haratake (Haratake, White-faced Oharata) Mosquitoes, Uskimorinokasa), Parietaria, Harunire (yellow, yu white skin, yuba), breadfruit, giant forsythia (sun dried), lizard carrot (party party), pecan nut, ganganana
(Shirubi, Suzuka Hana), Hikikoshi (Extended Life Grass), Hishi (Ryomi),
Pistachio, beet, hitsuba (stone reed), hitspotter fern, hinotainokozuchi (cow knee), hinoki, hiba, castor,
Sunflower, bell pepper, Himegama (incense blossom), Himematsutake (Kawariharatake, Hiromatsutake), Pimenta fruit, Juniper, Billacucu, Hyouyu fruit, Belowudo oil, Hiroohinagusa (Hakutooka), Loquat (loquat, loquat leaf), Betel wax (large clothing skin, Betel palm), spruce buds (southern wicker), butterflies, coltsfoot (winter flowers, wisteria leaves), fujibakama (orchid grass), wisteria beans (flat beans), grape berries or pericarp, seeds and leaves, beech, beetle Brazilian liquorice, Brazilian carrot, black currant fruit, blackberry, plum fruit, flucellaria, blueberry (Prunus avium), prunes, blonde psyllium, bundou (green beans), loofah, safflower (safflower), henneken, belladonna, berry fruits, Peruvian Berg, Boysenberry Fruit, Bow Few (Windbreak), Ho Lenovo, nightshade
(Torone), Onoki (Japanese magnolia, park), Bokeh (Gourd), Hosobananaokera (Aojutsu), Hosobabarengiku, Bodaiju (Bodai tree), Button (peony, Peony bark), Hops, Jojoba, White berry fruits, Hongshimeji , Hong Onik
Daigei), Maizulten Nanshaw (Tennan star), Maitake (Maitake), Ephedra (mao), Macadamia nut, Macri
(Seaman grass), magwa (mulberry white skin, mulberry leaf), magnolia splengeri, matabi (mokuten tate), matsukasa, matsuba, matsuhod
(Bukuryo), mayola (Hanaminka), malvanozadin (bitter), mulberry fruit, quince, mango, mangosteen, manshu walnut, mandarin fruit, mannentake (reishi), fruit of Rutaceae plant (komi), mishimasaiko (saiko), Mizokukushi (Hanbe Lotus), Misohagi (Chisatsuna), Mitsugashiwa, Mitsuba, Midorihakka, Mimosa, Myoga, Miracle Fruit Fruit, Myrrh, Mirobaran, Mukuge (Mokugei), Mukunoki, Mukuroji, Murasaki (Murasaki), Murasakikisukibu, Omurasakisikib (Purple pearls), purple corn, red swordfish (mother grass), mebaugi, melaleuca, melissa, melilot, melon fruit, sagebrush, mosouchikku, mokkou (wood incense), maple leaf daisies, peach leaves (peach leaves), fruits and seeds (peach peaches) ), Bean sprouts, morello cherry fruit, moroheiya (burlap), yakawa murasa Potatoes, Yakuchi
(Masutoshi), cornflower (cornflower), cornflower mint, yashabushi (arrow wheel) / Himeyashabushi / Obayashishabushi fruit, peel, fruit panicle, yachiyanagi, yatsude (octagonal gold plate), mistletoe (willow parasite), willow (kawayanagi, tayanagi, Weeping willow, red willow willow, pussy willow, inukoriyanagi, kinuyanagi, kolyanagi, unryuyanagi, miyayamanagi, yamayanagi, shirabanyanagi, tyrikkinuyanagi, foxgrew willow, dragonflies, purple wolfberry, beetle
(Land), alder (Yamaharu), bayberry (Yumebai), mugwort, eucalyptus, snowy citrus (tiger ear grass), yucca flebifolia, yuzu fruit, lily, yorigusa, mugwort
(Aiba leaf), lime fruit, rye, lacanca fruit, raspberry leaves / fruit, lavender, longan (longan meat), agave (Aono agave, fukurin agave), ryocha (green tea), apple fruit, gentian,
Lubas suavisimus (sweeten), litchi (litchi, lichi nucleus), lettuce (chisha), red currant fruit, lemon fruit, lemongrass, forsythia (forsythia: forsythia, forsythia), astragalus, wax palm, rokon (reed: Rone), Loganberry fruit, Rosemary
(Mannenrou), Rosehip (Nobara), Wasabi and Waremokou (Jiyu).

In addition, other seawaters, for example, seawater salt, dried seawater, inorganic salts obtained from the Dead Sea or the Atlantic or Pacific Ocean (sodium chloride, magnesium chloride, potassium chloride, etc.), sea mud / mud (fango) Kind, for example, sea mud or mud (silicon dioxide, silicon dioxide, etc.) in various places such as Italian Fango, German Fango, Eifel Fango, Freiburg Fango, etc.
Titanium dioxide, aluminum oxide, iron oxide, manganese oxide, sodium oxide, potassium oxide, magnesium oxide, calcium oxide, strontium oxide, sodium, potassium, magnesium, calcium, chromium,
Iron, copper, nickel, zinc, lead, manganese, arsenic, water, vitamin B, vitamin A, phytohormone "diberlin,
Cytokinin, absciscin ")

Examples of the seaweeds include seaweeds [green algae: Chlorella vulgaris, Chlorella pyrenoidsa, Chlorella ellipsoidia, Aonori (Usubaa nori, Susiaonori, Hiraaonori, Bowaoonori, Hosoedaoonori), and seaweed [Brown algae: Kombu algae: brown algae: brown algae: Kombu algae: brown algae: brown algae: brown seaweed: , Resiliconibu, hosomekobu, mishitishibu), seaweed, hirome, blue seaweed, giant kelp (macrocystis pilifera, macrocystis integrifolia, neocitys luetokeana), hijiki, hibamata), seaweed [red algae: hijirimen, maxa ( Tengsa),
Hirakusa, Onyxa, Obakusa, Kataobaxa, Yatabegusa, Yuikiri, Shimatengusa, Tosakanori, Togekirinsai, Akumasakirinsai, Kirinsai, Byaksinkirinsai, Tsunomata, Obatsunomata, Tochaka, Tohkanota, Tojika , Ibotsunomata, Yaleus Banori, Kagius Banori,
Suzius Banori, Hyus Banori, Akamomininori] and the like.

Other algae such as green algae (Chlamydomonas spp .: Chlamydomonas sp., Akayukimo, Dunaliella spp .: Dunaliella spp., Chlorococcus spp .: Chlorococcus, Kwanomimo spp .: Kwanomimo spp., Volvox spp. Spirogyra: Hizaori, Spirogyra, Tulsimidro, Hibimidro: Hibimidoro, Aosa: Anaoasa, Amiosa, Nagaosa, Kawanori: Kawanori,
Genus Fricciella, genus genus: medusa, asamidori ogusa, kawashiogusa, marimo, valonia: tamagobaronia, tamabaronia, magnum: tamatamamo, iwata: husaiwata, suricogita, heraiwirata, crocodile, crocus Sakibutimimil, Nagamil, Hiramil, and Casanori:
Casa nori, Juzumo
Mizojuzumo, Mizuazumimo, Korekaete, Tsutsumimo, Kikkogusa: Kikkogusa, Hitoexa: Hitoexa, Hirohanohiegusa, Usuhitoexa, Motsuhitoe, Sayamidro, Genus spp.

Blue-green algae (Genus L .: L., L., L., L .: L., mushrooms,
(Hassai, Yuremo, Racenmo (Spirulina) genus: Spirulina, Trichodesmium (Aiacacio), etc.).

Brown algae (Piraella spp .: Piraella spp., Shiomidoro spp .: Namiami sp., Isogrape spp .: Isogrape,
Genus Isogawara, genus Isogasula, genus genus: Gunsenkurogashira, genus Kashirazaki, genus Kashirazaki, genus Muchimo: genus Muchimo, Hiramutimo, Kebelligsa, genus Amis. Artemisia spp.
Genus Matsumo: genus Matsumo, genus matsumo: genus sylvestris, genus okinawa, genus okinawa-mozuku, genus niseftomozuku: niseftomozuku, futomozuku: genus futomozuku, ishimozuku: ishimozuku, kuromo: kuromo, nisemozuku: genus, spruce, spruce Ishige, Irolo, Icmegasa: Ichimegasa, Keyari: Keyari, Umibos: Umibos, Urushigusa: Urushigusa,
Species of the genus Coleoptera, Tobacco planta, Laminaria genus: Laminaria genus: Habanomodo genus: Habanomodo genus, Habanori genus: Havanori, genus Habanori: genus Habanori, genus bukuro: common bukuro, Ezobukuro genus: Ezobukuro, Fukuronori genus: Fukuronori, Watanabe Genus Kagomenori: Kagomenori, Muraridori: Murachidori, Shakusugusa: Sharks,
Genus Genus: Genus Genus, Genus Genus: Genus Genus: Genus Genus, Genus Kayamonori, Genus Kayamono, Genus Genus: Genus Ligustrum, Genus Tsurumo: Genus Turrum, Genus Anana: Genus Anastasia, Genus Ligustrum: Sujime, Genus Missiscoma: Genus Genus Ligustrum, G. , Onikombu, Goheikombu, Nagakombu, Pea kelp, Ochimikombu, Torokombu genus: Torokombu, Antokume genus: Antokume, Kajime: Kajime, Tsuruarame, Kurome, Kikuishikomu: Genus Kikuishi, Nejirekomu: Neshilecomb, Kuroshiomeko : Nekoshikambu,
Alame: Alame, Ainuwakame: Ainuwakame, Chigaiso, Oniwakameezoishige: Ezoishige, Yabanemoku: Yabanemoku, Rapamoku: Rapamoku, Jiromoku: Uganomok, Jiromoku, Hiemomoku, Honamomaku, Tamamomaku, Tamamomoku Akamoku, Shidamoku, Hondawara, Nejimoku, Narasamo, Mametawara, Tatsukuri, Yasumatamoku, Umitranoo, Oobamoku, Fushizushimoku, Hahakimokum, Togemoku, Jolemoku, Saw-mokum, Obanoki-moku, Genus genus: Genus
Bulukimo, genus cynomolgus: cynomolgus etc.).

Red algae (Genus genus: Ushikenori, Funorinoushike, Genus Amanori: Asakusanori, Susabinori,
Genus Upirinori, Onimanori, Tasa, Filitasa, Benitasa, Rhodocorton: Milnoveni, Akebonomozuku: Akebonomozuku, Konahada: Haikonahada, Yogorekonahada, Aokonahada, Sea Species: Acer genus : Larch, Fusanori: Fusanori, Nisefusanori: Nisefusanori,
Sodegarami: sodegarami, rattles: rattle, hiraragara, hirohatamataki: hirohatamatamadaki, tamamaidaki: tamaitadaki, kakenokenori: kaginori, kakenenori, tengusa, kurobana, kurobana, swordfish, swordfish, squirrel Genus: hibiroudo, himehibiroudo,
Genus genus: genus isensis, genus genus:
Genus spruce, Ryumonsou: Ryumonsou, Hera Ryumon, Nisekarequigusa: Nisekarequigusa, Okitsubara genus: Obaokitsubara, Akaba: Akaba, Malvaacaba, Naminohana: Genus Hosobanamino, Naminohanagosa, Coralthus Genus Ikawanokawa, Genus Kanokawa: Kinokawa, Genus Kaninote: Kaninote, Coralum: Coralum, Genus Mucadenori: Mucadenori, Sujimukade, Catanori, Hiramukade, Kyonohimo, Sakuranori, Nikunukade, Tambanori, Tsurutsuru,
Genus Isonohana: Nuracusa, Chronulaxa, Stinging genus, Hirakintoki Genus: Hirakintoki, Matabou: Matabou, Kintoki: Chabokintoki, Kintoki, Matsunori, Komenori, Tosakamatsu, Aedes pine, Kakureto: Genus Otokinari, Genus genus Genus Nagaobane, Genus Funori: Hanafunori, Fukuronori, Makhunori, Karenikusa Genus: Kalexigusa, Tosakamaki Genus: Hosobanotokamaki, Hirohanotosakamodoroki, Yatsudegatotoka, Kurotosakamodoki, Nezashinokidoka, Nezashinokinusakada Genus: Ezotosaka, Tsukasanori: Enashikarimenia, Otsukasanori, Hanagatakarimenia, Honoo: Honoo, Hikagenoito: Hikagenoito, Usuginu, Nikuhono: Nikuhono Oh, the genus Venice: genus Venice, genus Suskabeni: genus Suskebeni, genus Okamuragusa:
Yamadagusa, Mirin genus: Mirin, Hosobamilin, Tosakanori genus: Kikutosaka, Ezonameshi: Ezonameshi, Isomokka: Isomocca, Yukari: Yukari, Hosoyukari, Ibaranori: Ibaranori, Saidaibara, Tachiibara, Kagiinobaliso, Phyllophorus Isanthus, Atsubanori: Atsubanori,
Ogonori: Ogonori, Tsurushiramo, Shiramo, Ogogonori, Mizokonori, Kabanori, Tengusamodoki: Hachijotengusamodoki, Fushikrenori: Fushikenori, Namiiwatake: Namiiwatake, Spiraea:
Sponge, genus: ssp.
Genus: crocodile, saimi, crocodile, crocus genus: genus genus: moss genus, genus cynosum: squid moss, hosoibonori, nobonori, kurohaginnansou genus: kurohaginnansou, akabaginnansou genus: akabaginnansou, genus genus: genus serrata The genus Thaliosa: The genus Thalassium, Hanasakura, The genus Scrophulari: The genus Scrophulari, Schikonori, The genus Hananoeda: Hanaeda, The genus Hirata: The genus Hirata goat, The genus Darus: The darth, Masagoshibari, Anadarus, The genus Webagusa, Benifukunori
Genus Fusinagi: Fussushinagi, Himefusushinagi, Hirohafushinagisagi, Satsumagiso Genus: Hirawaginagiso, Usubawaginagiso, Igis Genus: Igis, Keigisu, Harigigissu, Haneigisu, Amigusa, Egonomida, Chrysanthemum Genus, Genus genus Family: Habutaenori, Konohanori, Suzuronori, Usveni genus: Usbeni, Hasujiginu: Hasujiginu, Nagakonohanori: Nagakonohanori, Suzuginu: Sujiginu, Atubastinu, Hyasubanori: Kagiusubanori, Jaureusubanoli, Jareusubanoli
Genus Ayanishiki: Genus Ayanishiki, Genus Ayaginu: Genus Ayaginu, Genus Dadia: Enashidazia, Genus Shimadagia: Isohagi, Simadadia, Dazimodoki: Genus Dazimomodoki, Genus Itogusa: Moleutogusa, Genus Genus: Makuri, Yanaginori, Hanayana, Rana Salix var. Genus Isomegusa: Isomegusa, Suzinasugusa: Suzinasugusa, Isobashou Genus: Isobashou, Fujimatsumo Genus: Fujimatsumo, Sawtooth Lilium: Scutellaria Rihiba, genus: genus kawamozuku, okamomozuku, himekamozuku, genus idiomyme: ideyugomegome, genus okitamozuku: genus okitimozuku,
Genus genus, genus chinorimo: chinorimo, genus genus: chisinori).

The axle algae (Characta spp., Rhododendron spp.,
Hossiturimo: Hossiturimo, Lichnotumnus, Flasksmo: Himefuramocha, Chaboflasmo, Tripera, etc., and yellow algae (Hikarimo: Hikarimo etc.).

Materials derived from animal raw materials include a cockscomb extract, a cow / human placenta extract, a pig / cattle stomach, duodenum or intestinal extract or a decomposition product thereof, and a pig / cattle spleen extract. Products or their degradation products, extracts of swine or bovine brain tissue, water-soluble collagen, collagen derivatives such as acylated collagen, collagen hydrolysates, elastin, elastin hydrolysates, water-soluble elastin derivatives, keratin and its decomposition products Or a derivative thereof, a silk protein and its degradation product or a derivative thereof, a pig / bovine blood cell protein degradation product (globin peptide), a pig / bovine hemoglobin degradation product (hemin, hematin, heme, protohem, heme iron, etc.), milk , Casein and its decomposition products or their derivatives, skim milk powder and its decomposition products or their derivatives, lactoferrin or its decomposition products, chicken egg ingredients Such as fish meat decomposition products.

(14) Microbial culture metabolites Yeast metabolites, yeast extract, rice ferment extract, rice bran ferment extract, euglena extract, lactic acid fermentation of raw milk and skim milk powder, trehalose or derivatives thereof.

(15) α-hydroxy acid Glycolic acid, citric acid, malic acid, tartaric acid, lactic acid and the like.

(16) Inorganic pigments Silicic anhydride, magnesium silicate, talc, kaolin,
Bentonite, mica, titanium mica, bismuth oxychloride, zirconium oxide, magnesium oxide, zinc oxide,
Titanium oxide, calcium carbonate, magnesium carbonate, yellow iron oxide, red iron oxide, black iron oxide, gunjou, chromium oxide,
Chromium hydroxide, carbon black, calamine, etc.

(17) UV absorbing / blocking agent p-aminobenzoic acid derivative, salicylic acid derivative, anthranilic acid derivative, coumarin derivative, amino acid compound,
Benzotriazole derivatives, tetrazole derivatives, imidazoline derivatives, pyrimidine derivatives, dioxane derivatives, camphor derivatives, furan derivatives, pyrone derivatives,
Nucleic acid derivatives, allantoin derivatives, nicotinic acid derivatives,
Vitamin B6 derivatives, benzophenones, oxybenzone, arbutin, guaiazulene, shikonin, baicalin, baicalein, berberine, neoheliopan, urocanic acid derivatives, escalol, zinc oxide, talc, kaolin and the like.

(18) Whitening agent p-aminobenzoic acid derivative, salicylic acid derivative, anthranilic acid derivative, coumarin derivative, amino acid compound,
Benzotriazole derivatives, tetrazole derivatives, imidazoline derivatives, pyrimidine derivatives, dioxane derivatives, camphor derivatives, furan derivatives, pyrone derivatives,
Nucleic acid derivatives, allantoin derivatives, nicotinic acid derivatives,
Vitamin B6 derivatives, oxybenzone, benzophenone, arbutin, guaiazulene, shikonin, baicalin, baicalein, berberine and the like.

(19) Tyrosinase activity inhibitor Ascorbic acid and its derivatives, hydroquinone and its glycosides, kojic acid and its derivatives, tocopherol and its derivatives, N-acetyltyrosine and its derivatives,
Glutathione, hydrogen peroxide, zinc peroxide, hydroquinone monobenzyl ether, placental extract, silk extract,
Plant extracts (mulberry, corn, smelt, Clara, mugwort, honeysuckle, yellowfin, dokudami, matsuhodo, adlay barley, edulis, hops, hawthorn, eucalyptus, achillea millefolium, althea, keihi, mankeishi, hamamerisu, yamaguwa, enmeshi, kyoto , Continued spouse,
Sun-dried, mao, sengoku, dokkatsu, psycho, boufu, hamabofu, ougon, peony skin, peonies, gennoshoko, kakkon, licorice, quintoko, aloe, ginger, safflower, green tea, black tea, asenyaku, etc.).

(20) Melanin dye reduction / decomposition Hydroquinone monobenzyl ether, phenylmercury hexachlorophene, mercuric oxide, mercurous chloride, aqueous hydrogen peroxide, zinc peroxide and the like.

(21) Acceleration of turnover / cell activation Hydroquinone, lactic acid bacteria extract, placenta extract, reishi extract, vitamin A, vitamin E, allantoin, spleen extract, thymus extract, yeast extract, fermented milk extract, plant extract ( Aloe, ogon, horsetail, gentian, burdock,
Sicon, carrot, hamamelis, hop, yokunin,
Odikoso, Assemble, Touki, Toukensenka, Amacha, Hypericum, Cucumber, Periwinkle,
Rosemary, parsley, etc.).

(22) Astringent Succinic acid, allantoin, zinc chloride, zinc sulfate, zinc oxide, calamine, zinc p-phenolsulfonate, potassium aluminum sulfate, resorcinol, ferric chloride, tannic acid (including catechin compound) Such.

(23) Active oxygen scavenger SOD, catalase, glutathione peroxidase and the like.

(24) Antioxidants ascorbic acid and its salts, stearic acid esters, tocopherol and its ester derivatives, nordihydroguaseletenic acid, butylhydroxytoluene (BHT),
Butylhydroxyanisole (BHA), hydroxytyrosol, parahydroxyanisole, propyl gallate, sesamol, sesamolin, gossypol and the like.

(25) Lipid peroxide production inhibitor β-carotene, plant extract (cultured sesame cells, amateur,
Hypericum, Hamamelis, Clove, Melissa, Emmeiso, Birch, Sage, Rosemary, Minami Minami,
Kina, age, ginkgo, green tea, etc.).

(26) Anti-inflammatory agent Ictamole, indomethacin, kaolin, salicylic acid, sodium salicylate, methyl salicylate, acetylsalicylic acid, diphenhydramine hydrochloride, d or dl-
Camphor, hydrocortisone, guaiazulene, camazulene, chlorpheniramine maleate, glycyrrhizic acid and its salts, glycyrrhetinic acid and its salts, licorice extract components, sicon extract, age extract extract and the like.

(27) Disinfectant / Disinfectant Acrinol, sulfur, benzalkonium chloride, benzethonium chloride, methylrosaniline chloride, cresol, calcium gluconate, chlorhexidine gluconate, sulfamine, mercurochrome, lactoferrin or its hydrolyzate, alkyldiaminoethyl chloride Glycine solution, isopropylmethylphenol, triclosan, quinidine, etc.

(28) Humidifier Glycerin, propylene glycol, 1,3-butylene glycol, hyaluronic acid and its salts, polyethylene glycol, chondroitin sulfate and its salts, water-soluble chitin or chitosan derivatives, pyrrolidone carboxylic acid and its salts, lactic acid Sodium, Mini Sasanishiki extract, etc.

(29) Hair preparations Selenium disulfide, alkylisoquinolinium bromide solution, zinc pyrithione, biphenamine, thianthol, castal tincture, show tincture, capsicum tincture, quinine hydrochloride, strong aqueous ammonia, potassium bromate, bromate Sodium, thioglycolic acid, etc.

(30) Antiandrogens Estrogen (eg, estrone, estradiol, ethinylestradiol), isoflavones, oxendrone, etc.

(31) Peripheral vascular blood flow promoter Vitamin E and its derivatives, assembly extract, garlic extract, carrot extract, aloe extract, gentian extract, touki extract, cepharanthin, carpronium chloride, minoxidil and the like.

(32) Local stimulants Pepper tincture, vanylamide nonylate, tincture tincture, tincture tincture, peppermint oil, l-menthol, camphor, benzyl nicotinate and the like.

(33) Metabolic activators Photosensitizer 301, hinokitiol, pantothenic acid and its derivatives, allantoin, placental extract, biotin, pentadecanoic acid glyceride and the like.

(34) Antiseborrheic agents Pyridoxine and its derivatives, sulfur, vitamin B6 and the like.

(35) Keratolytic agents Resorcin, salicylic acid, lactic acid and the like.

(36) Oxidizing agent Hydrogen peroxide solution, sodium persulfate, ammonium persulfate, sodium perborate, urea peroxide, sodium percarbonate, sodium tripolyphosphate, sodium bromate, potassium bromate, pyrroline peroxide Sodium acid, sodium orthophosphate, sodium silicate hydrogen peroxide adduct, sodium sulfate sodium chloride hydrogen peroxide adduct, β-tyrosinase enzyme solution, mushroom extract and the like.

(37) Hair remover Strontium sulfate, sodium sulfide, barium sulfide,
Inorganic reducing agents such as calcium sulfide; thioglycolic acid or salts thereof (calcium thioglycolate, sodium thioglycolate, lithium thioglycolate, magnesium thioglycolate, strontium thioglycolate, etc.).

(38) Hair swelling agent Ethanolamine, urea, guanidine and the like.

(39) Dyes 5-aminoorthocresol, 2-amino-4-nitrophenol, 2-amino-5-nitrophenol, 1-
Amino-4-methylaminoanthraquinone, 3,3'-
Iminodiphenol, 2,4-diaminophenoxyethanol hydrochloride, 2,4-diaminophenol hydrochloride, toluene-2,5-diamine hydrochloride, nitroparaphenylenediamine hydrochloride, paraphenylenediamine hydrochloride, N-phenylparaphenylenediamine hydrochloride, meta-hydrochloride Phenylenediamine, orthoaminophenol, N-phenylparaphenylenediamine acetate, 1,4-diaminoanthraquinone, 2,6-diaminopyridine, 1,5-dihydroxynaphthalene, toluene-2,5-diamine, toluene
3,4-diamine, nitroparaphenylenediamine, paraaminophenol, paranitroorthophenylenediamine, paraphenylenediamine, paramethylaminophenol, piclamic acid, sodium piclamate,
N, 'N-bis (4-aminophenyl) -2,5-diamino-1, -4-quinonediimine, 5- (2-hydroxyethylamino) -2-methylphenol, N-phenylparaphenylenediamine, metaamino Phenol, metaphenylenediamine, 5-aminoorthocresol sulfate, 2-amino-5-nitrophenol sulfate, orthoaminophenol sulfate, orthochloroparaphenylenediamine sulfate, 4,4'-diaminodiphenylamine sulfate,
2,4-diaminophenol sulfate, toluene-2 sulfate,
5-diamine, nitroparaphenylenediamine sulfate, paraaminophenol sulfate, paranitroorthophenylenediamine sulfate, paranitrometaphenylenediamine sulfate, paraphenylenediamine sulfate, paramethylaminophenol sulfate, metaaminophenol sulfate, metaphenylenediamine sulfate, catechol , Diphenylamine, α
-Naphthol, hydroquinone, pyrogallol, phloroglucin, gallic acid, resorcin, tannic acid, sodium 2-hydroxy-5-nitro-2 ', 4'-diaminoazobenzozen-5'-sulfonate, hematein and the like.

(40) Flavors Natural animal flavors such as musk, civet, castorium, ambergris, anise essential oil, angelica essential oil, ylang ylang essential oil, iris essential oil, fennel essential oil, orange essential oil, cananga essential oil, caraway essential oil, cardamom essential oil, Guayakwood essential oil, cumin essential oil, black letter essential oil, cinnamon essential oil, cinnamon essential oil, geranium essential oil, copaiba balsam essential oil, coriandel essential oil, perilla essential oil, cedarwood essential oil, citronella essential oil, jasmine essential oil, gingergrass essential oil, cedar essential oil, spearmint essential oil, western Mentha essential oil, Great Fengxiang essential oil, Tuberose essential oil, T-shaped essential oil, Orange flower essential oil, Winter green essential oil, Truval sam essential oil, Batturi essential oil, Rose essential oil, Palmarosa essential oil, Cypress essential oil, Hiba essential oil,
Sandalwood essential oil, Petit glen essential oil, Bay essential oil, Vetiva essential oil, Bergamot essential oil, Peruvian balsam essential oil, Boad rose essential oil, Camphor essential oil, Mandarin essential oil, Eucalyptus essential oil, Lime essential oil, Lavender essential oil, Linaloe essential oil, Lemongrass essential oil, Lemon essential oil, Rosemary Vegetable flavors such as essential oils and Japanese peppermint essential oils, and other synthetic flavors.

(41) Dyes and coloring agents Red cabbage dye, red rice dye, madder dye, anato dye, squid dye, turmeric dye, ende dye, krill dye, persimmon dye, caramel, gold, silver, gardenia dye, corn dye , Onion pigment, tamarind pigment, spirulina pigment, buckwheat whole plant pigment, cherry pigment, laver pigment, hibiscus pigment, grape juice pigment, marigold pigment, purple potato pigment, purple yam pigment, lac pigment, rutin, etc.

In addition, humectants, hormones, sequestering agents, pH adjusters, chelating agents, preservatives and anti-binders, fresheners, stabilizers, emulsifiers, animal and vegetable proteins and their decomposed products, animal and vegetable Vegetable polysaccharides and their degradation products, animal and vegetable glycoproteins and their degradation products, blood flow promoters, anti-inflammatory agents, anti-inflammatory agents, anti-allergic agents, cell activators, keratolytic agents, wound healing agents, hair removal Ingredients, foaming agents, thickeners, oral agents, deodorants / deodorants, bitters, seasonings, enzymes, etc., are expected to be used together with these to provide various additive and synergistic effects. it can.

The cosmetic composition containing the granules of the present invention can be prepared by a conventional method in the form of capsules, powders, granules, creams, sheets, liquids, solids, pastes, gels, / W emulsified, W / O emulsified and the like, cosmetic compositions, aqueous cosmetic compositions, emulsified cosmetic compositions, liquid crystal cosmetic compositions and the like. It is preferably aqueous. It can also be used in dosage forms such as a type that is only applied, a type that is washed away after massaging, and a type that is wiped off.

In the present invention, when blending the granules, it is sufficient to select the solvent in consideration of the content of the solvent used for the base, for example, water, alcohol and the like.

Further, the cosmetic composition containing the granules of the present invention can be used for the face, neck, hand, wrist, ankle,
It can be applied to the belly, calf, crotch, hair, scalp, etc., but it can be used more effectively by massaging or applying manually. When used by massaging or applying, for example, take a required amount of 2 to 3 g in your hand, apply it to the face, neck, hands, feet, hair, scalp, etc., and gently massage with your palm or fingertips (about 10 to 20). Seconds) and wipe off with tissue or cotton, or rinse off with water or hot water.

Specifically, for example, topical pharmaceutical preparations, lotions, emulsions, creams, ointments, lotions, oils, basic cosmetics such as packs, facial cleansers and skin cleansers, massage agents, cleansing agents, shampoos , Rinse, hair treatment, hair styling, perm, hair tonic,
Hair / scalp cosmetics such as hair dyes, hair restoration / hair nourishes, makeup cosmetics such as foundation, lipstick, blusher, eyeshadow, eyeliner, mascara, perfumes, bath agents, other toothpastes, mouthwash, It can be applied to various products such as gargle, deodorant and deodorant, sanitary cotton, wet tissue, and can be used for general foods and drinks.

The method of adding the granules of the present invention to the cosmetic composition may be added in advance or during the production, and may be appropriately selected in consideration of workability. .

[0079]

EXAMPLES The present invention will now be described with reference to production examples, test examples, and prescription examples, but the present invention is not limited to these examples.

(Production Example 1) Polyethylene powder (400 g) is taken, and granules are granulated with a stirring granulator using a 10% aqueous solution of hydroxypropylcellulose (200 g) as a water-soluble binder.

(Production Example 2) Polyethylene powder (400 g) is taken, and granules are granulated with a stirring granulator using a 7% aqueous solution of hydroxypropylcellulose (200 g) as a water-soluble binder.

(Production Example 3) Nylon powder (200 g), talc (200 g), crystalline cellulose (100 g), and chromium hydroxide (5.0 g) are added and mixed well. This is granulated with a stirring granulator using a 10% aqueous solution of polyvinylpyrrolidone (200 g) as a water-soluble binder.

(Production Example 4) Nylon powder (200 g), talc (200 g), crystalline cellulose (100 g), and chromium hydroxide (5.0 g) are added and mixed well. This is granulated with a stirring granulator using a 5% aqueous solution of polyvinylpyrrolidone (200 g) as a water-soluble binder.

(Test 1) Measurement of Granule Shape Various commercially available polystyrene powders, shea butter, carnauba wax, liquid paraffin, and walnut endocarp “Products of the present invention (particles are nearly spherical but slightly deformed) , Particles having a spherical shape, or particles having a very distorted shape "
Was measured for granule shape. <Measuring instrument and software> Hypermicroscope VH-
6110 (Keyence Corporation) Image Hyper I
I "Image processing and analysis software" (manufactured by Interquest Co., Ltd.) <Test method> Ten microparticles of polystyrene powder, shea butter, carnauba wax, liquid paraffin, and walnut endocarp of various shapes were arbitrarily extracted. The granule shape was read with a scope VH-6110, and the read granule shape was determined using the Image Hyper II “Image Processing Analysis Software” to determine the circularity coefficient and shape factor 2 by the following equations (Equations 1 and 2). In addition, as comparative products, those having a spherical granule shape (Comparative Product 1) and those having a very broken granular shape (Comparative Product 2) were measured. In addition, measurement is 1 per sample.
The test was performed 0 times, the average value was obtained, and the test results are shown in Tables 1 and 2. At the same time, the average particle size was measured.

[0085]

[Equation 1] Circularity coefficient = 4π × sum of area / perimeter ² (Circularity coefficient by equal-perimeter inequality; maximum for circular shape =
It is close to 0 for 1 and elongated. )

[0086]

## EQU2 ## Shape factor 2 α = π × (long axis of ellipse + short axis of ellipse) / 2 × perimeter (0 <α <1) (shape factor representing circularity; the closer to 1, the more likely the circle is)

[0087]

[Table 1]

[0088]

[Table 2]

(Test results) As shown in Tables 1 and 2, the granules of the present invention (polystyrene powder, shea butter, carnauba wax, liquid paraffin, walnut endocarp) had a circularity coefficient of 0.9.
78-0.411, shape factor 2 is 0.980-0.51
0, the comparative product 1 (having a spherical shape) had a circularity coefficient of 0.996 to 0.986, and the shape factor 2 was 0.99.
Comparative Example 2 (having a very deformed shape) has a circularity coefficient of 0.348 to 0.278.
It was confirmed that the shape factor 2 was in the range of 0.478 to 0.317.

(Test 2) Measurement of Granule Shape The granules obtained in the above Production Examples were adjusted to various shapes, arbitrarily selected, and the granule shape was measured. <Measuring instrument and software> Hypermicroscope VH-6110 (manufactured by Keyence Corporation) Image Hyper II "Image processing analysis software" (manufactured by Interquest Inc.) <Test method> Using the same method as in Test 1 described above, The granules obtained in the production examples were adjusted to various shapes, and 10 granules each arbitrarily extracted were subjected to hypermicroscope VH-611.
The granule shape was read at 0, and the circular shape coefficient and shape factor 2 were determined from the read granule shape using Image Hyper II “Image Processing Analysis Software” by the above equations (Equations 1 and 2). In addition, as comparative products, those obtained under the same conditions and having a spherical granule shape (Comparative Product 1) and those in which the granular shape was extremely distorted (Comparative Product 2) were measured. The measurement was performed 10 times for each sample, and the average value was obtained. The test results are shown in Table 3. At the same time, the average particle size was measured.

[0091]

[Table 3]

(Test Results) As shown in Table 1, the granules of the present invention have a circularity coefficient of 0.980 to 0.401 and a shape factor of 0.978 to 0.505. (Having a spherical shape) has a circularity coefficient of 0.997 to 0.9.
86, the shape factor 2 is 0.997 to 0.987, and the comparative product 2 (having a broken shape) has a circularity coefficient of 0.358.
~ 0.215, and the shape factor 2 was confirmed to be in the range of 0.452 to 0.248.

(Test 3) Safety test (1) Primary skin irritation test 2 g of the granules (product of the present invention) obtained in Production Examples 1 to 4 were mixed with 60 mL of purified water to prepare a Japanese white rabbit whose back was shaved. (Female, 3 per group, weight around 2.3kg)
Pressure was applied by hand and a massage was performed. Judgment after application
Erythema and edema were evaluated at 24, 48, and 72 hours by primary irritation scoring. The result was negative in all animals without any erythema and edema.

(Test 4) Safety test (2) Skin cumulative irritation test Granules (product of the present invention) 2 similarly obtained in Production Examples 1 to 4
g of purified water mixed with 60 mL of purified water, and the appropriate amount was applied to the skin of a Hartley-type guinea pig (female, 3 animals per group, about 320 g in weight) with shaved flank once a day, 5 times a week, and pressure was applied by hand. Was added and massaged. Massage application was performed over two weeks and shaving was performed on the last application day of each week. The judgment is
Erythema and edema were used as indices by a primary irritation scoring method on each application day and the day after the last application day. As a result, all animals were judged as negative without any erythema and edema over 2 weeks.

(Prescription example) Production of the granule-containing cosmetic composition of the present invention In accordance with the above evaluation results, the following formulation examples are shown. The formulation examples may be those manufactured by a conventional method in the manufacture of each product. Only the amount is shown. Further, the present invention is not limited to these.

(Formulation Example 1) Massage cream (O / W type) wt% 1. Vaseline 15.0 2. Liquid paraffin 50.0 3.1,3-butylene glycol 5.0 4. Glycerin monostearate 3.0 5. Polyoxyethylene (20) sodium Orthopentanoate monolaurate 2.0 6. A: Granules of Production Example 1 (product of the present invention) B: Granules of Production Example 2 (product of the present invention) C: Granules of Production Example 3 (product of the present invention) D: Granules (product of the present invention) E: Granules of Production Example 1 (Comparative Product 1) F: Granules of Production Example 2 (Comparative Product 1) G: Granules of Production Example 3 (Comparative Product 1) H: Granules of Production Example 4 ( Comparative Product 1) I: Granules of Production Example 1 (Comparative Product 2) J: Granules of Production Example 2 (Comparative Product 2) K: Granules of Production Example 3 (Comparative Product 2) L: Granules of Production Example 4 (Comparative Product) 2) * Any one of A to L 5.0 7. Perfume, preservative, antioxidant appropriate amount 8. Purified water 100 residue

(Formulation Example 2) Massage cream (W / O type)% by weight 1. Microcrystalline wax 9.0 2. Solid paraffin 2.0 3. Beeswax 3.0 4. Vaseline 5.0 5. Reduced lanolin 5.0 6. Squalane 34.0 7. Hexadecyl Adipic acid ester 10.0 8. Propylene glycol 5.0 9. Glycerin monooleate 3.5 10. Polyoxyethylene (20) sodium oryl monooleate 1.0 11. Granules of Production Example 2 (product of the present invention) 3.0 12. Fragrance, preservative Agent, antioxidant qs 13. Purified water 100 residue

(Formulation Example 3) Cleansing cream (W / O type)% by weight 1. Liquid paraffin 50.0 2. Beeswax 10.0 3. Sorbitan sesquioleate 1.0 4. Lanolin 3.0 5. Glycerin 4.0 6. Sulfur powder 3.0 7. Production Granules of Example 3 (product of the present invention) 3.0 8. Appropriate amount of fragrance, preservative, antioxidant 9. Residual amount of purified water 100

(Formulation Example 4) Cleansing cream (O / W type) wt% 1. Squalane 85.0 2. Sorbitan monooleate 4.0 3. A: Polystyrene powder (product of the present invention) B: Polystyrene powder (Comparative product 1) C: D: Shea butter (Comparative product) E: Shea butter (Comparative product 1) F: Shea butter (Comparative product 2) G: Carnauba wax (Inventive product) H: Carnauba wax (Comparative product 1) I: Carnauba wax (Comparative product 2) J: Liquid paraffin (Comparative product 1) K: Liquid paraffin (Comparative product 1) L: Liquid paraffin (Comparative product 2) M: Walnut endocarp (Product of the present invention) N: Walnut endocarp (Comparative product 1) O: Walnut endocarp (Comparative product 2) * Any one of A to O 5.0 4. Perfume, preservative, antioxidant qs 5. Purified water 100

(Formulation Example 5) Face Wash Cream% by Weight 1. Myristic acid 20.0 2. Stearic acid 5.0 3. Tallow fatty acid 3.0 4. Propylene glycol 9.0 5. Potassium hydroxide 6.0 6. Coconut oil fatty acid diethanolamide 6.0 7. Production example Granules 3 (product of the present invention) 5.0 8. Inner rind of walnut (product of the present invention) 5.0 9. Appropriate amount of fragrance, preservative, antioxidant 10. Purified water 100 residue

(Formulation Example 6) Paste peel off pack weight% 1. Titanium oxide 3.0 2. Kaolin 5.0 3. Granules of Production Example 4 (product of the present invention) 2.0 4. Sodium alginate 1.0 5. Ethanol 8.0 6.1,3-butylene Glycol 8.0 7. Perfume, preservative, antioxidant appropriate amount 8. Purified water 100 residue

(Formulation Example 7) Rinse-out clay pack weight% 1. Zinc oxide 3.0 2. Bentonite 5.0 3. Liquid paraffin (the present invention) 5.0 4. Glycerin 5.0 5. Propylene glycol 5.0 6. Ethanol 8.0 7. Perfume, preservative, antioxidant appropriate amount 8. Purified water 100 residue

(Formulation Example 8) Cold cream weight% 1. Salami beeswax 11.0 2. Liquid paraffin 22.0 3. Lanolin 10.0 4. Almond oil 15.0 5. Borax 0.5 6. Carnauba wax (the present invention) 3.0 7. Fragrance, preservative Agent, antioxidant qs 8. Purified water 100 residue

(Formulation Example 9) Powdered down weight% 1. Talc 81.0 2. Titanium oxide 5.0 3. Zinc laurate 5.0 4. Granules of Production Example 3 (product of the present invention) 6.0 5. Perfume, preservative, coloring pigment Appropriate amount

(Formulation Example 10) O / W type cream foundation weight% 1. stearic acid 4.0 2. glyceryl monostearate 3.0 3. cetanol 1.5 4. isopropyl myristate 7.0 5. liquid paraffin 10.0 6. beeswax 3.0 7. tri Ethanolamine 1.5 8. glycerin 3.0 9. bentonite 1.5 10. titanium oxide 8.0 11. talc 4.0 12. granules of Production Example 3 (product of the present invention) 6.0 13. perfume, preservative, antioxidant appropriate amount 14. purified water 100 Residue to do

(Formulation Example 11) Eye shadow weight% 1. Mica titanium 70.0 2. Zinc laurate 3.0 3. Granules of Production Example 4 (product of the present invention) 6.0 4. Shea butter (product of the present invention) 2.0 5. Colored pigment 1.5 6. Liquid paraffin 10.0 7. Octyl palmitate 5.0 8. Flavor, preservative, antioxidant qs 9. Purified water 100 residue

(Formulation Example 12) Solid blusher weight% 1. Talc 70.0 2. Kaolin 10.0 3. Zinc laurate 3.0 4. Precipitable calcium carbonate 6.0 5. Granules of Production Example 1 (product of the present invention) 6.0 6. Fluid Paraffin 1.5 7. Octyl palmitate 1.5 8. Color pigment appropriate amount 9. Perfume, preservative, antioxidant appropriate amount 10. Purified water 100 residue

(Formulation Example 13) Lipstick weight% 1. Candelilla wax 10.0 2. Carnauba wax 3.0 3. Microcrystalline wax 3.0 4. Lanolin 11.0 5. Liquid paraffin 10.0 6. Glycerin tri-2-ethylhexanoate 40.0 7. Castor Oil 18.0 8. Granules of Production Example 4 (product of the present invention) 5.0 9. Red 202, Red 226, Yellow 4 Aluminum Lake qs 10. Flavors, preservatives, antioxidants qs

(Formulation Example 14) Aqueous suspension type eyeliner weight% 1. Acrylic resin alkanolamine amine salt (40%) 4.0 2. Bentonite 5% dispersion 40.0 3.1,3-butylene glycol 8.0 4. Polyvinyl alcohol 3.0 5. Titanium oxide 2.0 6. Yellow iron oxide 20.0 7. Granules of Production Example 2 (product of the present invention) 5.0 8. Appropriate amount of fragrance, preservative, antioxidant 9. Purified water 100

(Formulation Example 15) O / W sunscreen emulsion weight% 1. stearic acid 2.0 2. self-emulsifying glyceryl monostearate 1.0 3. cetanol 1.0 4. dimethylpolysiloxane 3.0 5. liquid paraffin 10.0 6. Triethanolamine 1.5 7. Bentonite 0.5 8. Propylene glycol 3.0 9. Titanium oxide 5.0 10. Yellow iron oxide 20.0 11. Shea butter (this product) 3.0 12. Perfume, preservative, antioxidant qs 13. Purified water 100 And the rest

(Formulation Example 16) Deodorant powder weight% 1. Zinc oxide 4.9 2. Triclosan 0.1 3. Talc 82.0 4. Liquid paraffin 5.0 5. Granules of Production Example 1 (product of the present invention) 5.0 6. Walnut endocarp (book) Invented product) 3.0 7. Appropriate amount of fragrance, preservative, antioxidant

(Formulation Example 17) Nail enamel weight% 1. Nitrocellulose (1/4 second) 15.0 2. Alkyd resin 13.0 3. Ethyl acetate 14.0 4. Butyl acetate 20.0 5. Triethyl acetylcitrate 6.0 6. Butanol 5.0 7. Toluene 23.0 8. Granules of Production Example 4 (product of the present invention) 4.0 9. Appropriate amount of guanine 10. Appropriate amount of coloring pigment 11. Appropriate amount of pigment settling inhibitor

(Prescription Example 18) Shampoo wt% 1. Triethanolamine lauryl sulfate 5.0 2. Sodium polyoxyethylene lauryl ether sulfate 12.0 3.1,3-butylene glycol 4.0 4. Diethanolamide laurate 2.0 5. Disodium edetate 0.1 6. Shea butter (product of the present invention) 5.0 7. Appropriate amount of fragrance and preservatives 8. Residual amount with purified water 100

(Formulation Example 19) Body soap weight% 1. Potassium laurate 15.0 2. Potassium myristate 5.0 3. Propylene glycol 5.0 4. Walnut endocarp (product of the present invention) 5.0 5. Liquid paraffin (product of the present invention) 2.0 6. Appropriate amount of pH adjuster 7. Appropriate amount of preservative 8. Residue to make purified water 100

(Formulation Example 20) Rinse weight% 1. Stearyl trimethylammonium chloride 2.0 2. Cetostearyl alcohol 2.0 3. Polyoxyethylene lanolin ether 3.0 4. Propylene glycol 5.0 5. Shea butter (product of the present invention) 3.0 6. Fluid Paraffin (the product of the present invention) 3.0 7. Appropriate amount of pH adjuster 8. Appropriate amount of preservative 9. Residual to make purified water 100

(Formulation Example 21) Coating protective agent
A gauze or liniment cloth is impregnated with a prescription liquid prepared by mixing an appropriate amount of shea butter (the product of the present invention), antibiotics, anti-inflammation, etc., and attached to the wound. Further, the shea butter (the product of the present invention) may be directly applied locally and covered with gauze or the like.

(Test 4) Use Effect Test The effect of the cosmetic composition of the present invention actually used was examined. Use test for people with good skin condition 2
The test was performed by applying an appropriate amount of the massage cream (O / W type) of Formulation Example 1 to the face twice daily, morning and night, as a panel of 10 women aged 0 to 50 years, and using them continuously for one month. . As a control, granules of Production Examples 1 to 4 (products of the present invention)
In place of the above, those obtained by adding the comparative products 1 and 2 used in the test 2 and prescribing the same method were used. The evaluation was performed according to the following criteria. The results are shown in Table 4 and the numbers in the table represent the number of persons.

Granule skin contact (whether the skin has a rough or tingling sensation), granule irritation (whether there is a pleasant stimulus to the skin), cleaning effect of massage cream About, good: 5 points, slightly satisfied: 4 points,
Normal: 3 points, slightly unfavorable: 2 points, unfavorable:
Evaluation was made as one point.

[0119]

[Table 4]

(Test Results) As shown in Table 4, the massage cream containing the granules of the present invention had a better skin per granule and a stimulating sensation of the granules than the granules of Comparative Products 1 and 2,
In addition, good results were obtained for the cleaning effect of the massage cream itself.

(Test 5) Use Effect Test The effect of the cosmetic composition of the present invention actually used was examined. Use test for people with good skin condition 2
Cleansing cream of Formulation Example 4 (O / W type) twice daily, morning and night, with 10 women aged 0 to 40 as panelists
The test was carried out by applying an appropriate amount to the face and using it continuously for one month. As a control, instead of the product of the present invention, a comparative product of polystyrene powder, shea butter, carnauba wax, liquid paraffin, and walnut endocarp “Comparative product 1 (particle having a spherical particle shape) or Comparative product 2 ( (The shape of the particles is very distorted) "and formulated in the same manner. The evaluation was performed according to the following criteria.
Numerical values in the table represent the number of persons as shown in FIGS.

Granule per skin (whether there is a rough or tingling sensation on the skin), irritation of granules (whether or not there is a pleasant stimulus to the skin), cleaning effect of cleansing cream Good: 5 points, Satisfied: 4
Evaluation was made as 3 points, normal: 3 points, slightly unfavorable: 2 points, unpreferable: 1 point.

[0123]

[Table 5]

[0124]

[Table 6]

(Test Results) As shown in Tables 5 and 6, the cleansing cream containing the granules of the present invention had better skin irritation and perception of granules than the granules of Comparative Products 1 and 2, and Good cleaning effect of the cleansing cream itself was also obtained.

[0126]

The cosmetic composition of the present invention has a specific particle size
Since granules having a shape are blended, the granules themselves have a good skin contact, and the granules can have a pleasant stimulating feeling and have sufficient detergency.

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI theme coat ゛ (Reference) A61K 7/02 A61K 7/02 Z A 7/025 7/025 7/031 7/031 7/032 7 / 032 7/043 7/043 7/075 7/075 7/08 7/08 // C11D 17/06 C11D 17/06 F term (reference) 4C083 AA081 AA082 AA111 AA112 AA122 AB011 AB032 AB112 AB152 AB212 AB232 AB242 AB271 AB322 AB432 AB442 AC011 AC012 AC022 AC032 AC072 AC102 AC122 AC182 AC242 AC331 AC332 AC342 AC372 AC402 AC422 AC442 AC532 AC542 AC692 AC782 AC792 AC812 AC852 AC862 AD022 AD072 AD092 AD112 AD152 AD262 AD282 AD302 AD512 CC05 CC07 CC11 CC12 CC13 CC14 CC22 CC23 DD33 DD33 EE11 EE21 4H003 AB27 AB31 AB46 AC13 BA09 BA10 BA12 BA15 BA16 DA02 EA27 EB16 EB29 EB38 EB40 EB46 ED02 ED28 FA15 FA21 FA33

Claims (2)

[Claims] 1. A method according to claim 1, wherein one or more kinds of particles selected from organic polymers, fats and oils, waxes, mineral oils, inorganic substances, and plants have a circularity coefficient of 0.98 to 0.40 and a shape factor of 0.2. 98 ~
A cosmetic composition comprising 0.50 and granules having a particle size of 50 to 2000 μm. 2. Granules obtained by granulating a water-insoluble primary particle with a binder having a circularity coefficient of 0.98 to 0.40,
The shape factor 2 is in the range of 0.98 to 0.50 and the particle size is 50 to
A cosmetic composition, comprising granules having a size of 2000 μm.