JP2000023635A - Granule nutrient auxiliary food - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain the subject food accelerable neutralizing and decomposing fat and excreting action of effete matter in the body, activating immunocyte, contrivable an increase of albumin in blood and useful for prevention of cerebral infarction, hepatic disease, etc., by including coral granule and a branched chains-containing amino acid as principal components. SOLUTION: This food includes coral granules and a branched chains- containing amino acid such as L-(iso)leucine or L-valine as principal components. Preferably, 3,000 g of the granule nutrient auxiliary food contains 500 mg of Ca, 100 mg of Mg, 3.0 mg of iron, 5.0 mg of Zn, 401 U of vitamin D3, 600 mg of L-valine, 1,100 mg of L-leucine, 500 mg of L-isoleucine, 775 mg of rutin, 3.0 mg of proanthocyanidin, 1.5 mg of chondroitin and 7.5 mg of Monascus rice, and the granule is preferably packaged in a stick-like.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a powdered dietary supplement which is effective in supplementing daily eating habits and maintaining health.

[0002]

2. Description of the Related Art Mineral calcium,
Insufficient magnesium, sodium, potassium, etc. cause adult diseases such as cerebral infarction, myocardial infarction, hypertension, diabetes and cancer, liver disease, cataract, kidney disease, osteoporosis, etc., as well as stiff shoulders and migraines It has been found that this may cause attraction of children and blur of elderly people.

[0003] It is known that in order to maintain good health, a sufficient amount of heat and intake of proteins (amino acids) are required. However, those who have an irregular diet,
Despite a regular diet, those who eat a diet with an unbalanced nutrition tend to have a shortage of calories and protein intake, and have a blood albumin level of 3.5 g. / Dl or less and exhibit hypoalbuminemia.

[0004] Today, as is said to be the age of satiety, daily eating habits have been enriched and various liver diseases (eg, cirrhosis, acute hepatitis, chronic hepatitis, fat, etc.) have been accompanied by an increase in alcohol consumption. Liver and hepatocellular carcinoma), and such liver diseases are characterized in that subjective symptoms are unlikely to appear even if the disease progresses considerably. Therefore, it is necessary to keep a balanced diet in daily eating habits.

[0005] One of the characteristics of the liver disease is a decrease in serum albumin level. Albumin is a type of protein and accounts for about 2/3 of the protein contained in blood. However, it is known that as the condition of liver disease progresses, albumin synthesis decreases, albumin level in blood decreases, and other various organs are damaged.

[0006]

DISCLOSURE OF THE INVENTION The present invention has been made in view of the above-mentioned circumstances, and when eaten together with a daily meal, neutralization and decomposition of fat, promotion of excretion of waste products in the body, and immune cells To prevent cerebral infarction, cancer, and other diseases, further activate hepatocytes, increase albumin synthesis and prevent liver disease. The purpose is to provide food.

[0007]

According to the present invention, in order to achieve the above object, claim 1 comprises a coral powder and a branched-chain amino acid as main components. The granules are packed in a stick form to facilitate carrying and other daily handling.

[0008]

[Function] Coral contains various minerals, can maintain the body weakly alkaline, is effective in maintaining health, and separates acidic fats into saturated fatty acids and unsaturated fatty acids by minerals such as calcium and magnesium (fat Neutralization decomposition of fat), and the stickiness and strong acidity peculiar to fat are alleviated. At the same time, the minerals and fats are bound together, and the conjugates are excreted as they are from the intestine because the fatty acids and bile acids form chelate bonds and are hardly absorbed from the intestine.

As a result, there is also an effect that fat is not accumulated in the body, and an obesity-preventing action and a rapid excretion action of waste products in the body can be performed. In addition, calcium, which is a mineral component, has an activating effect on immune cells, and an effect of suppressing the generation of cancer cells has also been recognized.

[0010] Branched-chain amino acids are generic terms named for the characteristics of the chemical structural formulas contained in the essential amino acids. They increase the albumin level and promote protein synthesis in the liver, and are useful for the prevention of various liver diseases.

[0011] The decrease in the albumin level in the blood in the above-mentioned liver disease causes a drop in the osmotic pressure of the blood and makes it impossible to excrete water in the body as urine. Accumulate.

That is, 4-5 g / dl of albumin is required in the blood, and when the value falls below 3.5 g / dl, hypoalbuminemia is exhibited as described above, and 3 g / dl is exhibited.
When it is less than dl, edema of the limbs is caused.

[0013] In addition, various proteins such as albumin play an important role in producing hepatocytes.
Insufficient tiredness. Then, after being used in various forms in the body, the protein is converted into ammonia, and then detoxified from ammonia by the liver into urea, and finally excreted as urine from the kidney.

However, in the case of a liver disease, the liver cannot function to detoxify ammonia due to reduced liver function, and the excess of ammonia causes damage to other various organs.

At that time, it is the muscle that detoxifies ammonia instead of the liver, and the muscle decomposes the protein constituting itself and detoxifies ammonia by using the branched-chain amino acid contained therein.

As a result, the amount of branched-chain amino acids in the blood becomes insufficient and the ratio of other amino acids increases, and the balance of the amino acids in the blood is lost. Usually, in the case of hepatic dysfunction due to the liver disease, a method of directly injecting albumin is adopted as a temporary treatment. However, if the liver dysfunction is prolonged, this treatment is not promising. For this reason, it is desired that daily meals be meals necessary for maintaining a well-balanced health and liver disease and the like be prevented.

[0017]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS An embodiment of the present invention will be described below. The dietary supplement according to the present invention contains coral powder and branched-chain amino acids (L-leucine, L-isoleucine, L-valine) as main components. D ₃ , zinc, rutin, rice red yeast, chondroitin, proanthocyanidin and the like are added.

Through the steps shown in FIG. 1, the above-mentioned components are used to produce the powdered dietary supplement of the present invention. That is, each component is measured and mixed, a fragrance is added, the mixture is formed into granules, the particle size is adjusted by sieving, and the mixture is filled into a stick-shaped container for confirming the weight.

The coral granules are obtained by pulverizing so-called weathered reef corals, and contain calcium as a main component and also various mineral components such as magnesium, sodium and potassium. After the weathered reef coral is washed with water, it is dried and granulated by mechanically applying a shock or the like, and further promoted by heating or the like before applying a mechanical shock. .

The branched-chain amino acids (L-leucine, L-leucine)
Isoleucine and L-valine) are generic names named for the characteristics of chemical structural formulas contained in essential amino acids (amino acids that cannot be synthesized in the body and need to be taken in as food), and are easily soluble in water It is slightly soluble in hot ethanol and acetic acid, is commercialized by the enzyme, and is used for albumin synthesis in the liver.

Other iron (ferrous chloride) added above
Since it plays an important role in energy metabolism and DNA synthesis, it is a micronutrient essential for cell growth. If it is insufficient, it causes iron deficiency anemia, decreased immunity, and fatigue.

Vitamin D was discovered as an anti-Kur's disease factor, and subsequent studies have revealed that its action is expressed by active vitamin D ₃ produced by hydroxylation in the liver and kidney. It is used in the treatment of osteoporosis and works on intestinal endothelial cells to promote calcium reabsorption and also works on calcium reabsorption from renal tubules. Bone has a calcifying effect on bone tissue, formed by osteoblasts.

Zinc (seaweed powder) binds to DNA,
It is an important metal for living organisms such as apoptosis (cell death) depending on the amount of zinc in cells. Deficiency causes growth inhibition, arrest, and reproductive dysfunction, has the effect of protecting skin cancers caused by ultraviolet rays, is essential for protein synthesis, regulates cholesterol levels in blood, and regulates insulin components. Become. In addition, it has an important role in the development of the reproductive organs and hastens wound healing.

Rutin (enzyme-treated rutin) is a rhamnose glycoside of quercetin obtained from whole grass, enju leaves, immature fruits, potato flowers, etc., and contains about 3% in dry buckwheat. Have been.

Rutin has two flavonoids, retinol, in its molecule, which strengthens the connective tissue of capillaries. It also prevents blood from leaking out of capillaries. Capillary blood vessels have a temporary hemostatic effect due to the contracting action. Has a blood pressure lowering effect and prevents hypertension.

Proanthocyanidins (grape seed extract) prevent phenols found in red wine from oxidizing proteins. It has a therapeutic effect on vascular disorders,
It is known as a free radical remover (antioxidant) or a lipid peroxidation inhibitor. It lowers serum lipids and reduces the ability of platelets to aggregate. It is effective for protecting and reinforcing blood vessels.

Chondroitin (shark fin extract) binds to proteins to form chondroitin sulfate, a protein complex, and together with collagen, elastin, hyaluron, etc.
It is involved in the formation of connective tissue in living organisms. It is widely distributed in the epiphyses of bones that have an affinity for calcium ions and growing bones, and is involved in bone formation. It is also effective in preventing infection with viruses and bacteria. By supplementing and neutralizing harmful amines that are the cause of pain, it is effective for pain such as migraine and rheumatic joint pain, and has the function of storing water and nutrients in each tissue such as skin, muscles and organs, The amount decreases with age. Participates in aging prevention and beauty (skin freshness).

Rice red yeast rice is produced by breeding a fungus of the genus Monascus on rice. This rice red yeast rice has been used as a raw material of red wine and red milk rot in China, Taiwan and the like for a long time, and is regarded as a kind of crude drug. Ingested by hypertensive patients,
There is a step-down effect. Acetylcholine α-aminobutyric acid contained in rice red koji (GABA9 is an antihypertensive effect via the sympathetic nervous system.

The ingredients in 3000 mg of the powdery and granular supplement of the present invention having the above-mentioned effects are as follows.

Calcium 500 mg, magnesium 100 mg, iron 3.0 mg, zinc 5.0 mg, vitamin D ₃ 40 IU, L-valine 600 mg, L-leucine 1100 mg, L-isoleucine 500 mg, rutin 775 mg, proanthocyanidin 3.0 mg, chondroitin 1 <Experiment 1> Objective Effect on serum albumin level in experimental animals (rats) Method Male rats of Japan Charles River Co., Ltd. 9
The age of 486 to 731 g at the age of 40 months is used for each group.

Group A Suspension containing 3000 mg / pack of the granules of the present invention B Group Suspension containing 3000 mg × 3 times the amount of the granules of the present invention Group C Feed of Oriental Yeast Co., Ltd. Administration to rats Starting at 9 months of age, the test was performed once a day for 12 weeks using a gastric tube. Water was available ad libitum. After administration for 4, 8, and 12 weeks, the animals were euthanized, blood was collected from the abdominal aorta, and serum albumin level (Bromocresolgreen method (BCG method)).
er, TECTRON XA 18) was measured. Table 1 shows the results.

[Table 1] According to Table 1, a significant increase in albumin level was observed after 12 weeks in Group A, and after 8 and 12 weeks in Group B. C
There were no changes in the groups. <Experiment 2> Objective Effect on serum albumin level in liver injury model animals (chronic liver injury rats due to carbon tetrachloride) Method Chronic liver injury rats due to carbon tetrachloride 9-month-old body weight 251 to 311 g 40 mice per group Used.

Group D Suspension containing 3000 mg / pack of the granules of the present invention E Group Suspension containing 3000 mg × 3 times the amount of the granules of the present invention F Group Oriental Yeast feed Rat administration Starting at 9 months of age, the test was performed once a day for 12 weeks using a gastric tube. Water was available ad libitum. After administration for 4, 8, and 12 weeks, the animals were euthanized, blood was collected from the abdominal aorta, and the serum albumin level was measured in the same manner as in Experiment 1. Table 2 shows the results.

[Table 2] According to Table 2, in the D and E groups, a significant increase in albumin value was observed after 4 weeks, 8 weeks, and 12 weeks. No increase was observed in group F.

[0033]

The supplementary food of the present invention, when taken together with a daily meal, neutralizes and degrades fat, promotes the excretion of waste products in the body, activates immune cells, and enhances cerebral infarction, Experiment 1
As is clear from the results of (1) and (2), albumin in blood can be increased, hepatocytes can be activated, liver disease can be prevented, and health can be maintained. In addition, it has the effect of reducing general malaise, fatigue and the condition of liver disease.

[Brief description of the drawings]

FIG. 1 is a flowchart showing a process for producing a powdered dietary supplement according to the present invention.

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[Procedure amendment]

[Submission date] July 21, 1998 (7.27.2
1)

[Procedure amendment 1]

[Document name to be amended] Statement

[Correction target item name] 0028

[Correction method] Change

[Correction contents]

Rice red yeast rice is produced by breeding a fungus of the genus Monascus on rice. This rice red yeast rice has been used as a raw material of red wine and red milk rot in China, Taiwan and the like for a long time, and is regarded as a kind of crude drug. Ingested by hypertensive patients,
There is a step-down effect. Acetylcholine contained in rice red yeast rice
It is a hypotensive effect via the sympathetic nervous system by γ -aminobutyric acid (GABA ) . that's all

Continued on the front page F-term (reference) 4B018 LB10 LE02 LE03 LE06 MS07 MS14 MS18 4C087 AA01 AA02 BB04 CA01 MA02 MA34 MA41 MA43 MA52 NA05 NA09 ZA15 ZA21 ZA33 ZA40 ZA42 ZA70 ZA75 ZA81 ZA96 ZA97 ZB09 ZB22 ZBZC ZCZ FA53 KA17 MA02 MA04 MA30 MA54 MA61 MA63 MA72 NA05 NA09 ZA15 ZA21 ZA33 ZA40 ZA42 ZA70 ZA75 ZA81 ZA96 ZA97 ZB09 ZB22 ZB26 ZC21 ZC33 ZC35 ZC52 ZC75

Claims (2)

[Claims] 1. A dietary supplement comprising a coral powder and a branched-chain amino acid as main components. 2. The dietary supplement according to claim 1, wherein the powder is packaged in a stick form.