JO3376B1 - خليط متحد مضاد للفيروسات المسببة للاورام - Google Patents
خليط متحد مضاد للفيروسات المسببة للاورامInfo
- Publication number
- JO3376B1 JO3376B1 JOP/2012/0207A JOP20120207A JO3376B1 JO 3376 B1 JO3376 B1 JO 3376B1 JO P20120207 A JOP20120207 A JO P20120207A JO 3376 B1 JO3376 B1 JO 3376B1
- Authority
- JO
- Jordan
- Prior art keywords
- retroviral combination
- retroviral
- combination
- darunavir
- ritonavir
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
- B29C48/03—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
- B29C48/04—Particle-shaped
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
- B29C48/25—Component parts, details or accessories; Auxiliary operations
- B29C48/78—Thermal treatment of the extrusion moulding material or of preformed parts or layers, e.g. by heating or cooling
- B29C48/80—Thermal treatment of the extrusion moulding material or of preformed parts or layers, e.g. by heating or cooling at the plasticising zone, e.g. by heating cylinders
- B29C48/83—Heating or cooling the cylinders
- B29C48/832—Heating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Abstract
توجد هناك مركبات صيدلانية من ريتونافير ودارونافير كما توجد هناك طرق لانتاجه.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2538MU2007 | 2007-12-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
JO3376B1 true JO3376B1 (ar) | 2019-03-13 |
Family
ID=54289250
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JO2008578A JO2814B1 (ar) | 2007-12-24 | 2008-12-24 | خليط متحد مضاد للفيروسات المسببة للأورام |
JOP/2012/0207A JO3376B1 (ar) | 2007-12-24 | 2012-07-29 | خليط متحد مضاد للفيروسات المسببة للاورام |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JO2008578A JO2814B1 (ar) | 2007-12-24 | 2008-12-24 | خليط متحد مضاد للفيروسات المسببة للأورام |
Country Status (20)
Country | Link |
---|---|
US (1) | US9339470B2 (ar) |
EP (2) | EP2242482B1 (ar) |
JP (2) | JP2011507940A (ar) |
CN (2) | CN101925350B (ar) |
AP (2) | AP2013007064A0 (ar) |
AT (1) | ATE555778T1 (ar) |
AU (1) | AU2008339633A1 (ar) |
BR (1) | BRPI0819534A2 (ar) |
CA (1) | CA2710605C (ar) |
DK (1) | DK2242482T3 (ar) |
ES (2) | ES2385819T3 (ar) |
GT (1) | GT200800303A (ar) |
HK (1) | HK1149905A1 (ar) |
JO (2) | JO2814B1 (ar) |
MX (1) | MX2010007083A (ar) |
PA (1) | PA8809601A1 (ar) |
PE (2) | PE20140926A1 (ar) |
RU (2) | RU2531089C2 (ar) |
WO (1) | WO2009081174A2 (ar) |
ZA (1) | ZA201004505B (ar) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PA8809601A1 (es) | 2007-12-24 | 2009-07-23 | Cipla Ltd | Combinación anti-retroviral |
US8921415B2 (en) | 2009-01-29 | 2014-12-30 | Mapi Pharma Ltd. | Polymorphs of darunavir |
CA2784398A1 (en) | 2010-01-28 | 2011-08-04 | Mapi Pharma Limited | Process for the preparation of darunavir and darunavir intermediates |
CA2822639A1 (en) * | 2010-12-22 | 2012-06-28 | The Feinstein Institute For Medical Research | Methods for treating systemic lupus erythematosus using hiv protease inhibitors |
KR101817991B1 (ko) * | 2011-07-07 | 2018-01-12 | 얀센 사이언시즈 아일랜드 유씨 | 다루나비어 제제 |
BR112014000290B1 (pt) * | 2011-07-07 | 2022-05-10 | Gilead Sciences, Inc. | Forma de dosagem oral de combinação de darunavir, processo para preparação de uma forma de dosagem oral e uso de granulado de darunavir |
JP6314131B2 (ja) * | 2012-05-03 | 2018-04-18 | シプラ・リミテッド | 抗レトロウイルス組成物 |
RU2505286C1 (ru) * | 2012-12-29 | 2014-01-27 | Открытое Акционерное Общество "Фармасинтез" | Фармацевтическая композиция для лечения вич-инфекции, способ ее получения и способ лечения |
EP3038607A2 (en) | 2013-08-29 | 2016-07-06 | Teva Pharmaceutical Industries Ltd. | Unit dosage form comprising emtricitabine, tenofovir, darunavir and ritonavir and a monolithic tablet comprising darunavir and ritonavir |
WO2015155673A1 (en) | 2014-04-08 | 2015-10-15 | Teva Pharmaceutical Industries Ltd | Unit dosage form comprising emtricitabine, tenofovir, darunavir and ritonavir |
WO2018029561A1 (en) * | 2016-08-08 | 2018-02-15 | Hetero Labs Limited | Anti-retroviral compositions |
RU2659693C1 (ru) * | 2017-06-30 | 2018-07-03 | Общество с ограниченной ответственностью "Изварино Фарма" | Фармацевтическая композиция, обладающая активностью против ВИЧ-инфекции |
EP3569225A1 (en) | 2018-05-18 | 2019-11-20 | Pharmaceutical Oriented Services Ltd | Solid dispersion containing ritonavir |
CN114146061B (zh) * | 2020-09-07 | 2023-06-30 | 歌礼生物科技(杭州)有限公司 | 包含固体分散体的蛋白酶抑制剂增效组合物及其制备方法 |
RU2760129C1 (ru) * | 2020-12-04 | 2021-11-22 | Общество с ограниченной ответственностью "АМЕДАРТ" | Твёрдая фармацевтическая композиция для изготовления перорального антиретровирусного терапевтического средства |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5141867A (en) | 1987-02-02 | 1992-08-25 | E. I. Du Pont De Nemours And Company | Nucleotide sequence encoding a human immunodeficiency virus antigen |
JP2994031B2 (ja) | 1988-12-20 | 1999-12-27 | クラリティ テクノロジーズ インコーポレイテッド | Hiv−1又はhiv−2抗体の存在又は量の確定方法、免疫特異的試薬、合成ペプチド、診断用キット、hiv−1又はhiv−2抗体の調製方法、免疫原及び抗体 |
WO1990007199A1 (en) | 1988-12-20 | 1990-06-28 | Mawzones Developments Limited | Focussing device for a microwave antenna |
US5696270A (en) * | 1989-05-23 | 1997-12-09 | Abbott Laboratories | Intermediate for making retroviral protease inhibiting compounds |
US6248574B1 (en) | 1989-12-13 | 2001-06-19 | Avigdor Shaffermann | Polypeptides selectively reactive with antibodies against human immunodeficiency virus and vaccines comprising the polypeptides |
IL102092A (en) | 1991-06-11 | 1996-11-14 | Microgenesys Inc | Use of recombinant VIH protein wrapped in VIH abduction drug and a pharmaceutical preparation containing the accumulated protein |
EP0674513B1 (en) | 1992-12-29 | 1996-09-25 | Abbott Laboratories | Retroviral protease inhibiting compounds |
IL110752A (en) | 1993-09-13 | 2000-07-26 | Abbott Lab | Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor |
IL111991A (en) | 1994-01-28 | 2000-07-26 | Abbott Lab | Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent |
US6037157A (en) | 1995-06-29 | 2000-03-14 | Abbott Laboratories | Method for improving pharmacokinetics |
WO1999067254A2 (en) | 1998-06-23 | 1999-12-29 | The United States Of America Represented By The Secretary, Department Of Health And Human Services | Multi-drug resistant retroviral protease inhibitors and use thereof |
TWI286476B (en) | 2001-12-12 | 2007-09-11 | Tibotec Pharm Ltd | Combination of cytochrome P450 dependent protease inhibitors |
RU2275361C3 (ru) | 2002-11-20 | 2021-10-01 | Джапан Тобакко Инк. | Соединение 4-оксохинолина и его применение в качестве ингибитора вич интегразы |
US8025899B2 (en) * | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
US20050048112A1 (en) | 2003-08-28 | 2005-03-03 | Jorg Breitenbach | Solid pharmaceutical dosage form |
US8377952B2 (en) * | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
ES2313394T3 (es) * | 2004-07-08 | 2009-03-01 | Tibotec Pharmaceuticals Ltd. | Combinacion de transcriptasa inversa anti-hiv e inhibidores de proteasa. |
JP2008520672A (ja) * | 2004-11-16 | 2008-06-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | チプラナビルとダルナビルの共投与によるhiv感染症の治療方法 |
TWI471145B (zh) * | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
SI2051703T1 (sl) | 2005-12-14 | 2011-01-31 | Cipla Ltd | Farmacevtski sestavki, ki vsebujejo inhibitorje nukleotidne in nukleozidne reverzne transkriptaze (kot tenofovir in lamivudin) v različnih delih dozirne oblike |
PA8809601A1 (es) | 2007-12-24 | 2009-07-23 | Cipla Ltd | Combinación anti-retroviral |
-
2008
- 2008-12-23 PA PA20088809601A patent/PA8809601A1/es unknown
- 2008-12-23 GT GT200800303A patent/GT200800303A/es unknown
- 2008-12-24 CA CA2710605A patent/CA2710605C/en not_active Expired - Fee Related
- 2008-12-24 ES ES08864958T patent/ES2385819T3/es active Active
- 2008-12-24 CN CN200880125422.4A patent/CN101925350B/zh not_active Expired - Fee Related
- 2008-12-24 AU AU2008339633A patent/AU2008339633A1/en not_active Abandoned
- 2008-12-24 AP AP2013007064A patent/AP2013007064A0/xx unknown
- 2008-12-24 MX MX2010007083A patent/MX2010007083A/es active IP Right Grant
- 2008-12-24 AT AT08864958T patent/ATE555778T1/de active
- 2008-12-24 JO JO2008578A patent/JO2814B1/ar active
- 2008-12-24 EP EP08864958A patent/EP2242482B1/en not_active Not-in-force
- 2008-12-24 AP AP2010005325A patent/AP2855A/xx active
- 2008-12-24 EP EP12166011.2A patent/EP2505193B1/en active Active
- 2008-12-24 CN CN201310534883.XA patent/CN103638032A/zh active Pending
- 2008-12-24 RU RU2010131006/15A patent/RU2531089C2/ru not_active IP Right Cessation
- 2008-12-24 ES ES12166011.2T patent/ES2674730T3/es active Active
- 2008-12-24 JP JP2010540173A patent/JP2011507940A/ja active Pending
- 2008-12-24 US US12/810,301 patent/US9339470B2/en active Active
- 2008-12-24 PE PE2013001497A patent/PE20140926A1/es not_active Application Discontinuation
- 2008-12-24 DK DK08864958.7T patent/DK2242482T3/da active
- 2008-12-24 PE PE2008002186A patent/PE20091530A1/es not_active Application Discontinuation
- 2008-12-24 BR BRPI0819534-0A patent/BRPI0819534A2/pt not_active Application Discontinuation
- 2008-12-24 WO PCT/GB2008/004291 patent/WO2009081174A2/en active Application Filing
-
2010
- 2010-06-25 ZA ZA2010/04505A patent/ZA201004505B/en unknown
-
2011
- 2011-04-27 HK HK11104197.0A patent/HK1149905A1/xx not_active IP Right Cessation
-
2012
- 2012-07-29 JO JOP/2012/0207A patent/JO3376B1/ar active
-
2014
- 2014-03-26 RU RU2014111723A patent/RU2675831C2/ru not_active IP Right Cessation
- 2014-08-06 JP JP2014160671A patent/JP2015007071A/ja active Pending
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