JO3362B1 - الحفظ بالتبريد لخلايا سرطان الموت الخلوي المبرمج للاستعمال في العلاج المناعي ضد السرطان - Google Patents
الحفظ بالتبريد لخلايا سرطان الموت الخلوي المبرمج للاستعمال في العلاج المناعي ضد السرطانInfo
- Publication number
- JO3362B1 JO3362B1 JOP/2014/0365A JOP20140365A JO3362B1 JO 3362 B1 JO3362 B1 JO 3362B1 JO P20140365 A JOP20140365 A JO P20140365A JO 3362 B1 JO3362 B1 JO 3362B1
- Authority
- JO
- Jordan
- Prior art keywords
- cancer
- immunotherapy
- cells
- cryopreservation
- immunotherapy against
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 201000011510 cancer Diseases 0.000 title abstract 4
- 238000009169 immunotherapy Methods 0.000 title abstract 4
- 230000001640 apoptogenic effect Effects 0.000 title 1
- 238000005138 cryopreservation Methods 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 230000030833 cell death Effects 0.000 abstract 1
- 210000004443 dendritic cell Anatomy 0.000 abstract 1
- 230000037449 immunogenic cell death Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
- A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0278—Physical preservation processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464402—Receptors, cell surface antigens or cell surface determinants
- A61K39/464403—Receptors for growth factors
- A61K39/464406—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ ErbB4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464493—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; Prostatic acid phosphatase [PAP]; Prostate-specific G-protein-coupled receptor [PSGR]
- A61K39/464494—Prostate specific antigen [PSA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464493—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; Prostatic acid phosphatase [PAP]; Prostate-specific G-protein-coupled receptor [PSGR]
- A61K39/464495—Prostate specific membrane antigen [PSMA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/58—Prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/59—Reproductive system, e.g. uterus, ovaries, cervix or testes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
يتم في هذه الوثيقة وصف طريقة يمكن الاعتماد عليها لإعداد لقاح فعال مفيد لعلاج مناعي تتضمن الطريقة خطوة الحفظ بالتبريد لجمهرة خلايا لتخضع لموت الخلايا المناعي، واستخدام مثل هذه الخلايا لتنشيط الخلايا الجذعية لاستخدامها في العلاج المناعي. في تجسيد معين، تتضمن الطريقة الحفظ بالتبريد لخلايا سرطانية لتخضع لموت خلايا، والتي يمكن استخدامها لإعداد تركيبة دوائية لعلاج مناعي ضد السرطان.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/142,448 US9562219B2 (en) | 2013-12-27 | 2013-12-27 | Cryopreservation of apoptotic cancer cells for use in immunotherapy against cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
JO3362B1 true JO3362B1 (ar) | 2019-03-13 |
Family
ID=52292898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2014/0365A JO3362B1 (ar) | 2013-12-27 | 2014-12-17 | الحفظ بالتبريد لخلايا سرطان الموت الخلوي المبرمج للاستعمال في العلاج المناعي ضد السرطان |
Country Status (9)
Country | Link |
---|---|
US (5) | US9562219B2 (ar) |
KR (1) | KR20160113611A (ar) |
AR (1) | AR100666A1 (ar) |
AU (1) | AU2014372723A1 (ar) |
CA (1) | CA2935126A1 (ar) |
JO (1) | JO3362B1 (ar) |
MX (1) | MX2016008432A (ar) |
TW (1) | TW201528948A (ar) |
WO (1) | WO2015097037A1 (ar) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9562219B2 (en) | 2013-12-27 | 2017-02-07 | SOTIO a.s. | Cryopreservation of apoptotic cancer cells for use in immunotherapy against cancer |
JP2019517537A (ja) * | 2016-06-06 | 2019-06-24 | ソティオ エイ. エス. | がん免疫療法 |
KR102256337B1 (ko) * | 2017-10-17 | 2021-05-26 | (주)노터스생명과학 | 조직이식을 위한 세포배양액을 포함하는 면역억제제 |
KR20200116112A (ko) | 2018-01-25 | 2020-10-08 | 소티오 에이.에스. | 화학요법에 순차적인 수지상 세포 백신접종 |
CA3087823A1 (en) | 2018-01-25 | 2019-08-01 | SOTIO a.s. | Dendritic cell vaccination in parallel to chemotherapy |
WO2020187975A1 (en) | 2019-03-19 | 2020-09-24 | SOTIO a.s. | Patient selection for treatment with dendritic cell vaccination |
JP7340240B2 (ja) * | 2019-08-26 | 2023-09-07 | 学校法人関西医科大学 | 細胞又は組織にアポトーシスを誘導する方法 |
WO2021113328A1 (en) | 2019-12-03 | 2021-06-10 | Neuvogen, Inc. | Tumor cell vaccines |
EP4232078A1 (en) * | 2020-10-20 | 2023-08-30 | The Regents of The University of California | Attenuated cancer cells and methods related thereto |
WO2022171792A1 (en) | 2021-02-12 | 2022-08-18 | Sctbio A.S. | Patient selection for treatment with dendritic cell vaccination |
AU2022325498A1 (en) | 2021-08-13 | 2024-02-01 | Cytune Pharma | Il-2/il-15rbetagamma agonist combination with antibody-drug conjugates for treating cancer |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6602709B1 (en) | 1998-02-20 | 2003-08-05 | The Rockefeller University | Methods for use of apoptotic cells to deliver antigen to dendritic cells for induction or tolerization of T cells |
AU757443B2 (en) * | 1998-05-11 | 2003-02-20 | I.D.M. Immuno-Designed Molecules | New apoptotic bodies, monocyte derived cells containing the same, a process for their preparation and their uses as vaccines |
WO2003012085A1 (en) * | 2001-07-30 | 2003-02-13 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Antigen presenting cells, method for their preparation and their use for cancer vaccines |
WO2006047515A2 (en) | 2004-10-25 | 2006-05-04 | Baylor Research Institute | Dendritic cells loaded with heat shocked melanoma cell bodies |
WO2006095330A2 (en) | 2005-03-10 | 2006-09-14 | Yeda Research And Development Co. Ltd. | Methods and immunogenic cell preparations for treating antigen-associated diseases |
BR112012020303A2 (pt) | 2010-02-19 | 2019-09-24 | Cadila Pharmaceuticals Ltd | "composição estável de células mortas com propriedades imunogênicas substancialmente retidas, e, processo e método de preparação da composição." |
US20130011438A1 (en) | 2011-07-05 | 2013-01-10 | SOTIO a.s. | Means And Methods For Active Cellular Immunotherapy Of Cancer By Using Tumor Cells Killed By High Hydrostatic Pressure and Dendritic Cells |
EP2543386A1 (en) | 2011-07-05 | 2013-01-09 | Sotio a.s. | Means and methods for active cellular immunotherapy of cancer by using tumor cells killed by high hydrostatic pressure |
US9562219B2 (en) | 2013-12-27 | 2017-02-07 | SOTIO a.s. | Cryopreservation of apoptotic cancer cells for use in immunotherapy against cancer |
-
2013
- 2013-12-27 US US14/142,448 patent/US9562219B2/en active Active
-
2014
- 2014-12-17 WO PCT/EP2014/078247 patent/WO2015097037A1/en active Application Filing
- 2014-12-17 CA CA2935126A patent/CA2935126A1/en not_active Abandoned
- 2014-12-17 AU AU2014372723A patent/AU2014372723A1/en not_active Abandoned
- 2014-12-17 JO JOP/2014/0365A patent/JO3362B1/ar active
- 2014-12-17 MX MX2016008432A patent/MX2016008432A/es unknown
- 2014-12-17 KR KR1020167020102A patent/KR20160113611A/ko active Search and Examination
- 2014-12-23 AR ARP140104908A patent/AR100666A1/es unknown
- 2014-12-25 TW TW103145564A patent/TW201528948A/zh unknown
-
2016
- 2016-12-22 US US15/388,972 patent/US9895430B2/en active Active
-
2018
- 2018-01-10 US US15/866,896 patent/US10155033B2/en not_active Expired - Fee Related
- 2018-11-02 US US16/179,159 patent/US10561717B2/en active Active
-
2019
- 2019-12-30 US US16/730,667 patent/US20200147191A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR20160113611A (ko) | 2016-09-30 |
AR100666A1 (es) | 2016-10-26 |
US9895430B2 (en) | 2018-02-20 |
US20180125956A1 (en) | 2018-05-10 |
US9562219B2 (en) | 2017-02-07 |
TW201528948A (zh) | 2015-08-01 |
US20190070278A1 (en) | 2019-03-07 |
CA2935126A1 (en) | 2015-07-02 |
WO2015097037A1 (en) | 2015-07-02 |
US20150184130A1 (en) | 2015-07-02 |
US10155033B2 (en) | 2018-12-18 |
US20170232086A1 (en) | 2017-08-17 |
MX2016008432A (es) | 2016-10-28 |
US20200147191A1 (en) | 2020-05-14 |
US10561717B2 (en) | 2020-02-18 |
AU2014372723A1 (en) | 2016-06-16 |
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