ITRM20090478A1 - DEVICE FOR RAPID ANALYSIS OF BIOLOGICAL MATERIAL. - Google Patents

DEVICE FOR RAPID ANALYSIS OF BIOLOGICAL MATERIAL. Download PDF

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Publication number
ITRM20090478A1
ITRM20090478A1 IT000478A ITRM20090478A ITRM20090478A1 IT RM20090478 A1 ITRM20090478 A1 IT RM20090478A1 IT 000478 A IT000478 A IT 000478A IT RM20090478 A ITRM20090478 A IT RM20090478A IT RM20090478 A1 ITRM20090478 A1 IT RM20090478A1
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IT
Italy
Prior art keywords
container
main body
tank
strips
biological material
Prior art date
Application number
IT000478A
Other languages
Italian (it)
Inventor
Claudio Filippo Maria Trovato
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Chemimed Ltd
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Priority to ITRM2009A000478A priority Critical patent/IT1398772B1/en
Publication of ITRM20090478A1 publication Critical patent/ITRM20090478A1/en
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Publication of IT1398772B1 publication Critical patent/IT1398772B1/en

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0038—Devices for taking faeces samples; Faecal examination devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0621—Control of the sequence of chambers filled or emptied
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0672—Integrated piercing tool
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Description

DISPOSITIVO PER ANALISI RAPIDA DI MATERIALE BIOLOGICO DEVICE FOR FAST ANALYSIS OF BIOLOGICAL MATERIAL

DESCRIZIONE DESCRIPTION

La presente invenzione si riferisce ad un dispositivo per analisi rapida di materiale biologico, particolarmente idoneo ad analisi su feci o siero sanguigno e da impiegarsi in associazione con un contenitore di tale materiale in forma liquida. The present invention relates to a device for rapid analysis of biological material, particularly suitable for analysis on feces or blood serum and to be used in association with a container of said material in liquid form.

Attualmente, l’analisi delle feci viene eseguita prelevando una porzione del campione fornito mediante uno strumento in genere in forma di paletta ed inserendo tale strumento recante la porzione di feci prelevata in un contenitore riempito di liquido solvente. In tal modo, si ottiene un campione di feci in forma sostanzialmente liquida. Currently, faecal analysis is performed by taking a portion of the sample supplied by means of an instrument generally in the form of a scoop and inserting this instrument bearing the portion of feces taken into a container filled with solvent liquid. In this way, a stool sample in substantially liquid form is obtained.

Il contenitore suddetto reca inferiormente, ossia da parte opposta rispetto alla sede di inserimento dello strumento di prelievo, un fondo lacerabile. Tale fondo viene appunto lacerato mediante l’estremità superiore di un ulteriore contenitore-serbatoio entro il quale viene così travasato il liquido biologico. The aforesaid container has a bottom that can be torn off, ie on the opposite side with respect to the insertion seat of the withdrawal instrument. This bottom is in fact torn by the upper end of a further container-tank into which the biological liquid is thus transferred.

Da tale contenitore-serbatoio il liquido biologico viene poi selettivamente introdotto in provette di reagenti o similari per l’esecuzione dei test richiesti. From this container-tank, the biological liquid is then selectively introduced into test tubes of reagents or similar for the execution of the required tests.

Le modalità di esecuzione delle analisi delle feci appena descritte presentano l’importante inconveniente di non garantire standard igienici e sanitari adeguati, in quanto il campione subisce ripetuti travasi in condizioni non ermetiche. The methods of carrying out the analysis of the faeces described above have the important drawback of not guaranteeing adequate hygienic and sanitary standards, as the sample undergoes repeated decanting in non-hermetic conditions.

Inoltre, le modalità di analisi risultano globalmente complesse e poco idonee a garantire risultati rapidi. Furthermore, the methods of analysis are globally complex and unsuitable for guaranteeing rapid results.

Pertanto, il problema tecnico posto e risolto dalla presente invenzione à ̈ quello di fornire un dispositivo di analisi che consenta di ovviare agli inconvenienti sopra menzionati con riferimento alla tecnica nota. Therefore, the technical problem posed and solved by the present invention is that of providing an analysis device which allows to overcome the drawbacks mentioned above with reference to the known art.

Tale problema viene risolto da un dispositivo secondo la rivendicazione 1. This problem is solved by a device according to claim 1.

Caratteristiche preferite della presente invenzione sono presenti nelle rivendicazioni dipendenti della stessa. Preferred features of the present invention are present in the dependent claims thereof.

La presente invenzione fornisce alcuni rilevanti vantaggi. Il vantaggio principale consiste nel fatto che il dispositivo dell’invenzione consente l’esecuzione di test multipli sulle feci mediante un unico sistema portatile chiuso ermeticamente dal contenitore sopra introdotto, assicurando quindi condizioni sanitarie ed igieniche di piena sicurezza e rendendo il test di esecuzione più semplice e rapida. In particolare, il dispositivo à ̈ particolarmente idoneo anche per auto-test. The present invention provides some relevant advantages. The main advantage consists in the fact that the device of the invention allows the execution of multiple tests on feces by means of a single portable system hermetically sealed by the container introduced above, thus ensuring sanitary and hygienic conditions of full safety and making the test execution simpler and faster. In particular, the device is also particularly suitable for self-tests.

Il dispositivo à ̈ anche specificamente adatto, oltre che per l’esame delle feci, anche per quello del siero sanguigno, come verrà illustrato in maggiore dettaglio più avanti. The device is also specifically suitable, as well as for the examination of faeces, also for that of blood serum, as will be explained in greater detail below.

Altri vantaggi, caratteristiche e le modalità di impiego della presente invenzione risulteranno evidenti dalla seguente descrizione dettagliata di alcune forme di realizzazione, presentate a scopo esemplificativo e non limitativo. Verrà fatto riferimento alle figure dei disegni allegati, in cui: Other advantages, characteristics and methods of use of the present invention will become evident from the following detailed description of some embodiments, presented by way of non-limiting example. Reference will be made to the figures of the attached drawings, in which:

ƒ la Figura 1 mostra una vista in prospettiva parzialmente in esploso di una forma di realizzazione preferita del dispositivo secondo la presente invenzione, rappresentato congiuntamente ad un contenitore di campione biologico; Figure 1 shows a partially exploded perspective view of a preferred embodiment of the device according to the present invention, shown together with a biological sample container;

ƒ la Figura 2 mostra una vista in prospettiva di parte del contenitore di Figura 1, nel quale à ̈ stata rimossa una copertura laterale; Figure 2 shows a perspective view of part of the container of Figure 1, in which a side cover has been removed;

ƒ la Figura 3 mostra una vista in pianta dal basso del contenitore di Figura 1; e Figure 3 shows a bottom plan view of the container of Figure 1; And

ƒ la Figura 4 mostra una vista laterale del contenitore di Figura 1. ƒ Figure 4 shows a side view of the container of Figure 1.

Con riferimento alle Figure sopra introdotte, un dispositivo portatile di analisi rapida di materiale biologico secondo una forma di realizzazione preferita dell’invenzione à ̈ complessivamente denotato con 1. Il dispositivo 1 della forma di realizzazione qui considerata à ̈ particolarmente idoneo all’analisi delle feci. With reference to the Figures introduced above, a portable device for rapid analysis of biological material according to a preferred embodiment of the invention is generally denoted by 1. The device 1 of the embodiment considered here is particularly suitable for analysis of feces.

Il dispositivo 1 à ̈ concepito per l’uso in associazione ad un contenitore di feci disciolte mediante apposito solvente liquido, anch’esso rappresentato in Figura 1 e denotato con 100. Device 1 is designed for use in association with a container of feces dissolved by means of a suitable liquid solvent, also represented in Figure 1 and denoted by 100.

Tale contenitore 100, di per sé noto, comprende: Said container 100, known per se, comprises:

− uno strumento di raccolta di un campione di feci 101, ∠’an instrument for collecting a stool sample 101,

− un corpo di contenimento cilindrico 102 per alloggiare lo strumento 101 ed il solvente liquido delle feci, ed ∠’a cylindrical containment body 102 to house the instrument 101 and the liquid solvent of the feces, and

− una porzione inferiore 103 recante un fondo lacerabile 104 ed in comunicazione di fluido con l’interno del corpo di contenimento 102. ∠’a lower portion 103 bearing a tear-off bottom 104 and in fluid communication with the interior of the containment body 102.

Tipicamente, lo strumento 101 Ã ̈ portato su di un tappo 105 per la chiusura ermetica del contenitore 100. Typically, the instrument 101 is carried on a cap 105 for the hermetic closure of the container 100.

Il dispositivo 1 comprende innanzitutto un corpo principale 2 sostanzialmente piatto. Nel presente esempio, il corpo principale 2 à ̈ realizzato mediante accoppiamento a tenuta di un primo ed un secondo guscio, rispettivamente 3 e 4, sostanzialmente piatti. Il primo guscio 3 reca una prima ed una seconda finestra trasparente, rispettivamente 5 e 6, attraverso le quali sono visibili mezzi di analisi rapida 7 di cui si dirà a breve. The device 1 first of all comprises a substantially flat main body 2. In the present example, the main body 2 is made by means of a sealed coupling of a first and a second shell, respectively 3 and 4, which are substantially flat. The first shell 3 has a first and a second transparent window, respectively 5 and 6, through which rapid analysis means 7 are visible, which will be discussed shortly.

Il corpo principale 2 reca inoltre un serbatoio 8, che nel presente caso à ̈ integrale con o rigidamente connesso a il primo guscio 3 e chiuso lateralmente dal secondo guscio 4. Il serbatoio 8 reca superiormente un mezzo di lacerazione 9 – nel presente esempio in forma di becco - atto a penetrare il fondo 104 del contenitore di materiale biologico 100 in modo che quest’ultimo si trasferisca entro il serbatoio 8 stesso. Quando si realizza tale accoppiamento, il contenitore 100 ed il corpo principale 2 formano un unico sistema chiuso ermeticamente, in particolare rispetto a fuoriuscite di liquido. The main body 2 also bears a tank 8, which in the present case is integral with or rigidly connected to the first shell 3 and closed laterally by the second shell 4. The tank 8 carries a tearing means 9 at the top - in the present example in the form of a spout - suitable for penetrating the bottom 104 of the container of biological material 100 so that the latter is transferred into the tank 8 itself. When this coupling is made, the container 100 and the main body 2 form a single hermetically closed system, in particular with respect to liquid leaks.

Come menzionato sopra, entro il corpo principale 2 sono alloggiati mezzi di analisi rapida complessivamente denotati con 7. Nel presente esempio di realizzazione preferita, tali mezzi 7 sono in forma una pluralità di strisce reagenti, in particolare cinque e denotate rispettivamente con 71-75, alloggiate in vani ricavati in una cornice periferica 70. As mentioned above, the main body 2 accommodates rapid analysis means, denoted as a whole by 7. In the present example of preferred embodiment, these means 7 are in the form of a plurality of reagent strips, in particular five and denoted respectively by 71-75, housed in compartments obtained in a peripheral frame 70.

Le strisce 71-75 si estendono lateralmente al serbatoio 8 e sono in comunicazione di fluido con l’interno di quest’ultimo, essendo interposte fra i due gusci 3 e 4 ed in particolare recando estremità affacciate all’interno del serbatoio 8 stesso, e come meglio visibile in Figura 2. The strips 71-75 extend laterally to the tank 8 and are in fluid communication with the inside of the latter, being interposed between the two shells 3 and 4 and in particular having ends facing the inside of the tank 8 itself, and as best seen in Figure 2.

In tal modo, quando il campione in forma liquida si riversa dal contenitore 100 al serbatoio 8 del dispositivo 1, la disposizione complessiva consente che le strisce 71-75 vengano pervase, ossia imbibite, da detto materiale biologico in forma liquida e possano così fornire un risultato di test eseguito su tale materiale. Tale risultato à ̈ leggibile attraverso la prima finestra 5 del corpo principale 2, ad esempio in forma di una modifica del colore delle strisce interessate. Una legenda in tal senso e/o un’indicazione in merito al tipo di test associato a ciascuna striscia può essere riportata in corrispondenza della porzione di striscia stessa che attraversa la seconda finestra 6. In alternativa, quest’ultima può essere sostituita da un elemento adesivo recante le suddette informazioni. In this way, when the sample in liquid form pours from the container 100 to the tank 8 of the device 1, the overall arrangement allows the strips 71-75 to be pervaded, i.e. soaked, by said biological material in liquid form and can thus provide a test result performed on that material. This result is readable through the first window 5 of the main body 2, for example in the form of a change in the color of the affected strips. A legend to this effect and / or an indication of the type of test associated with each strip can be reported in correspondence with the portion of the strip itself that crosses the second window 6. Alternatively, the latter can be replaced by an adhesive element bearing the above information.

In base ad una applicazione alternativa, il dispositivo sopra descritto può essere impiegato per analisi del siero sanguigno. In tal caso, a livello del contenitore 100 potrà essere prevista una membrana selettivamente permeabile che consenta appunto al solo siero di riversarsi o percolare nel serbatoio 8. According to an alternative application, the device described above can be used for blood serum analysis. In this case, a selectively permeable membrane may be provided at the level of the container 100 which allows just the whey to pour or percolate into the tank 8.

La presente invenzione à ̈ stata fin qui descritta con riferimento a forme preferite di realizzazione. È da intendersi che possano esistere altre forme di realizzazione che afferiscono al medesimo nucleo inventivo, come definito dall’ambito di protezione delle rivendicazioni qui di seguito riportate. The present invention has been described heretofore with reference to preferred embodiments. It is to be understood that other embodiments may exist which pertain to the same inventive nucleus, as defined by the protection scope of the claims reported below.

Claims (9)

RIVENDICAZIONI 1. Dispositivo portatile (1) di analisi rapida di materiale biologico, in particolare feci o siero, per uso in associazione con un contenitore (100) di detto materiale in forma liquida, comprendente: - un corpo principale (2); - un serbatoio (8), solidale a detto corpo principale (2) e recante superiormente un mezzo di lacerazione (9) atto a penetrare il fondo (104) del contenitore (100) di materiale biologico in modo che quest’ultimo si trasferisca entro il serbatoio (8) stesso; e - mezzi di analisi rapida (7) sostanzialmente in forma di una o più strisce diagnostiche (71-75), disposte entro detto corpo principale (2) lateralmente rispetto a detto serbatoio (8) ed in comunicazione di fluido con l’interno di quest’ultimo, la disposizione complessiva essendo tale che dette una o più strisce (71-75) sono atte ad essere pervase dal materiale biologico in forma liquida ed a fornire un risultato di test eseguito su tale materiale. CLAIMS Portable device (1) for the rapid analysis of biological material, in particular feces or serum, for use in association with a container (100) of said material in liquid form, comprising: - a main body (2); - a tank (8), integral with said main body (2) and bearing at the top a tearing means (9) able to penetrate the bottom (104) of the container (100) of biological material so that the latter is transferred within the tank (8) itself; And - rapid analysis means (7) substantially in the form of one or more diagnostic strips (71-75), arranged inside said main body (2) laterally with respect to said tank (8) and in fluid communication with the inside of the latter, the overall arrangement being such that said one or more strips (71-75) are able to be permeated by the biological material in liquid form and to provide a test result performed on such material. 2. Dispositivo (1) secondo la rivendicazione 1, in cui detto corpo principale (2) reca almeno una finestra sostanzialmente trasparente (5) attraverso la quale à ̈ leggibile il risultato del test fornito da dette una o più strisce (71-75). Device (1) according to claim 1, wherein said main body (2) carries at least one substantially transparent window (5) through which the test result provided by said one or more strips (71-75) can be read. . 3. Dispositivo (1) secondo la rivendicazione 1 o 2, in cui detto corpo principale (2) reca almeno una od una ulteriore finestra (6) sostanzialmente trasparente attraverso la quale à ̈ leggibile il tipo di test eseguito da dette una o più strisce (71-75). 3. Device (1) according to claim 1 or 2, wherein said main body (2) carries at least one or a further substantially transparent window (6) through which the type of test performed by said one or more strips can be read. (71-75). 4. Dispositivo (1) secondo una qualsiasi delle rivendicazioni precedenti, in cui dette una o più strisce diagnostiche (71-75) sono disposte in modo tale da risultare in comunicazione di fluido con l’interno di detto serbatoio (8). Device (1) according to any one of the preceding claims, in which said one or more diagnostic strips (71-75) are arranged in such a way as to result in fluid communication with the interior of said tank (8). 5. Dispositivo (1) secondo una qualsiasi delle rivendicazioni precedenti, in cui dette una o più strisce diagnostiche (71-75) recano estremità affacciate all’interno di detto serbatoio (8). 5. Device (1) according to any one of the preceding claims, in which said one or more diagnostic strips (71-75) have ends facing the inside of said tank (8). 6. Dispositivo (1) secondo una qualsiasi delle rivendicazioni precedenti, in cui detto corpo principale (2) à ̈ sostanzialmente piatto. Device (1) according to any one of the preceding claims, wherein said main body (2) is substantially flat. 7. Kit di analisi rapida di materiale biologico, in particolare feci o siero, comprendente un dispositivo secondo una qualsiasi delle rivendicazioni precedenti ed un contenitore (100) di detto materiale in forma liquida recante detto fondo lacerabile (104). 7. Rapid analysis kit for biological material, in particular faeces or serum, comprising a device according to any one of the preceding claims and a container (100) of said material in liquid form bearing said tear-off bottom (104). 8. Kit secondo la rivendicazione precedente, in cui detto contenitore (100) reca una membrana selettivamente permeabile al solo siero 8. Kit according to the preceding claim, wherein said container (100) carries a membrane selectively permeable to the serum only 9. Kit secondo la rivendicazione 7 o 8, in cui detti dispositivo (1) e contenitore (100) sono selettivamente impegnabili l’uno con l’altro in modo da realizzare un sistema ermetico.9. Kit according to claim 7 or 8, wherein said device (1) and container (100) are selectively engageable with each other so as to provide a hermetic system.
ITRM2009A000478A 2009-09-21 2009-09-21 DEVICE FOR RAPID ANALYSIS OF BIOLOGICAL MATERIAL. IT1398772B1 (en)

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WO2005045408A1 (en) * 2003-10-28 2005-05-19 American Bio Medica Corporation Lateral flow immunoassay device
US20050220668A1 (en) * 2004-04-06 2005-10-06 Bio/Data Corporation Disposable test device with sample volume measurement and mixing methods
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DE102007014729A1 (en) * 2007-03-24 2008-09-25 Michael Matallana Kielmann Device for processing lateral flow immunoassay testing

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5119830A (en) * 1991-04-03 1992-06-09 Code Blue Medical Corporation Analytical specimen cup with testing means
US20020173047A1 (en) * 2001-05-18 2002-11-21 Hudak Robert Thomas In line test device and methods of use
WO2005045408A1 (en) * 2003-10-28 2005-05-19 American Bio Medica Corporation Lateral flow immunoassay device
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