CN201555723U - Device integrating sampling and reacting - Google Patents
Device integrating sampling and reacting Download PDFInfo
- Publication number
- CN201555723U CN201555723U CN2009200741639U CN200920074163U CN201555723U CN 201555723 U CN201555723 U CN 201555723U CN 2009200741639 U CN2009200741639 U CN 2009200741639U CN 200920074163 U CN200920074163 U CN 200920074163U CN 201555723 U CN201555723 U CN 201555723U
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Abstract
The utility model discloses a device integrating sampling and reacting, which comprises an upper reaction tube and a lower reaction tube which are connected through an intermediate junction part; a breakable device filled with reaction solution is arranged in the upper reaction tube; a hollow inscribed geometrical column structure is arranged in the lower reaction tube; a reaction reagent strip is arranged in a gap where the geometrical column is inscribed with lower reaction tube; a sampling device is connected to one end of the intermediate junction part toward the upper reaction tube; a water dropper structure is arranged on one end of the intermediate junction part toward the lower reaction tube; a closed structure is arranged at the connection part of the sampling device and the intermediate junction part; a hollow passage structure is designed on the periphery at the connection part of the sampling device and communicated with the water dropper structure. The utility model can achieve integrated functions of sampling, storing and reacting.
Description
Technical field
The utility model relates to a kind of reagent strip device, particularly relates to a kind of reagent strip device of centralized procurement sample reaction one.
Background technology
Existing a lot of tests can use reagent strip, occult blood as colloidal gold immunity chromatography, ight soil and detect etc.No matter be the test of which kind of type, its form is the reagent strip form all, during test, all is aided with liquid and promotes reaction to finish.The step of general test comprises that sampling, sample preparation, application of sample, reaction carry out, finish reaction.Present each step that is operating as is all independently carried out.But there are problems such as sampling is too much, sampling inconvenience, sample preparation is difficult, test environment is open in these method of testings.
With ight soil occult blood the test be example, whole test needs the ight soil detectable bar of occulting blood, a special-purpose sampling rod (being used for the picking fecal specimens), a sample processing tube (as the sample preparation container), and need a collection containers (being used for collecting and depositing fecal specimens), the collection of its sample and processing procedure are:
1. with sample processing tube, vertically place and handle on the pipe holder, and in sample hose, add 0.6ml sample preparation liquid;
2. take a sample from the different parts of patient's ight soil at random with special-purpose sampling rod, sampling amount is as the criterion with the small circle ring that is stained with special-purpose sampling rod front end;
3. with stirring with sample preparation liquid in the sample insertion sample hose of getting on the special-purpose sampling rod, standby.
Ight soil is occulted blood, and to detect step as follows:
1. the sample that will be collected in the sample processing tube stirs as far as possible, allows sample mix with sample preparation liquid fully;
2. tear aluminium foil bag, take out the detectable bar;
3. the end with detectable bar application of sample vertically immerses in the sample mix liquid, attention can not submergence detectable bar " MAX " line above part; Can after immersing 15 seconds, take out the detectable bar and lie against horizontal table top, leave standstill the appearance of waiting for the result;
4. observations.
Above whole operation process relates to a plurality of containers, and each step operation steps all needs openable container again, gathers, handles sample or carry out application of sample.This both had been unfavorable for operation, had also increased the pollution probability of operating personnel and test itself simultaneously.In addition, relate to particular sample such as ight soil, itself also is a greatly test for operating personnel's psychological bearing capability.
The utility model content
The technical problems to be solved in the utility model provides the device of a kind of centralized procurement sample reaction one, so as to reach take a sample-preserve-react integrated series.
For solving the problems of the technologies described above, the device of centralized procurement sample reaction one of the present utility model comprises reaction tube and following reaction tube, and reaction tube connects by intermediate connecting part up and down;
The broken device that fills reactant liquor is set in the last reaction tube;
How much rod structures of hollow inscribe are set in the following reaction tube, in the slit of geometry post and following reaction outer tube inscribe, the reaction reagent bar are set;
Intermediate connecting part connects sampler towards last reaction tube one end, towards following reaction tube one end emitter structure is set.
Described reaction tube up and down is the test tube shape structure of end sealing, an end opening, reaction tube is connected with the two ends of intermediate connecting part by the syndeton of openend up and down, wherein, the syndeton of reaction tube can be screw socket, bayonet socket or other structures that is used to connect up and down, bayonet socket or other structures that is used to be connected that the corresponding syndeton of intermediate connecting part can match for the screw thread that matches with screw socket, with reaction tube bayonet socket up and down.
The described device that breaks is arranged at blind end near last reaction tube.
The junction of described sampler and intermediate connecting part is a closed construction, logical structure and communicate with emitter structure in being designed to around the sampler junction.
Described sampler comprises sampling swab, spiral sampling head or cotton swab, and its sampling head is near last reaction tube blind end, and can break the device horizontal level and intersects.
The two-port diameter of described intermediate connecting part is more smaller than last reaction tube and following reaction tube, common little 1-5mm, and the mesozone diameter of intermediate connecting part is the same big with the diameter of reaction tube up and down.
Described how much posts are interchangeable how much posts, equal up and down opening, its length greater than reaction reagent bar length less than following tube length of reaction tube, and with the difference of following tube length of reaction tube less than reaction reagent bar length, how much close reaction tube blind ends down of post one end, geometric configuration can be geometric configuratioies such as triangle, square.
Described reaction reagent bar is conventional reaction reagent bar, comprise immunochromatography reagent bar, the ight soil detectable bar of occulting blood, the reaction surface of reaction reagent bar is towards the observer, and the sample application zone of reaction reagent bar is near the blind end of following reaction tube, and reaction reagent bar quantity can determine as required.
When using the device of above-mentioned centralized procurement sample reaction one, to go up reaction tube opens, after exposing the sampler sampling, to go up the reaction tube openend upwards, the remainder of device is combined with last reaction tube, reaction tube on the closure, whole device is closed structure, then, can break device by broken, making wherein, reagent flows out, after the sample of obtaining on the sampler fully mixes, will install inversion again, make mixed liquor come together in the water dropper place by the hollow channel of middle coupling arrangement, gently squeeze into reaction tube, make mixed liquor compile reaction tube bottom down by how much post hollow spaces of hollow.Liquid level rises to and can touch reaction reagent bar bottom, and reaction is carried out automatically, thereby reaches the integrated series operation of sampling-preservation-reaction.
Owing to adopt said structure, the utility model can be realized the incorporate reagent strip test of sampling-preservation-reaction.
Description of drawings
Below in conjunction with accompanying drawing and embodiment the utility model is described in further detail:
Fig. 1 is the device synoptic diagram of the centralized procurement sample reaction one among the embodiment 1;
Figure 1A is a following reaction tube square section synoptic diagram among Fig. 1;
Fig. 2 is the screw socket synoptic diagram all established of the openend of reaction tube up and down among the embodiment 1;
Fig. 3 is the synoptic diagram of the connecting pipe ingredient among the embodiment 1;
Fig. 3 A is square section, the middle interconnecting piece position synoptic diagram of Fig. 3;
Fig. 3 B is the middle interconnecting piece position cross-sectional schematic of Fig. 3;
Fig. 4 is the synoptic diagram of the connecting pipe screw thread among the embodiment 1;
Fig. 5 is the device synoptic diagram of the centralized procurement sample reaction one among the embodiment 2;
Fig. 5 A is a following reaction tube square section synoptic diagram among Fig. 5;
Fig. 6 is the bayonet socket synoptic diagram all established of the openend of reaction tube up and down among the embodiment 2;
Fig. 7 is the synoptic diagram of the connecting pipe ingredient among the embodiment 2;
Fig. 7 A is square section, the middle interconnecting piece position synoptic diagram of Fig. 7;
Fig. 7 B is the middle interconnecting piece position cross-sectional schematic of Fig. 7;
Fig. 8 is the synoptic diagram of the connecting pipe bayonet socket among the embodiment 2.
Description of reference numerals is as follows among the figure:
1 is last reaction tube, and 2 are following reaction tube, and 3 is connecting pipe,
4 is screw socket, and 5 is screw thread, and 6 is the reaction reagent bar,
7 is sampler, and 8 for can break device, and 9 is embedded pipe,
21 square section for following reaction tube, 31 is the solid section of sampler jack,
32 is water dropper, and 33 is the middle interconnecting piece position of connecting pipe, and 34 is aperture,
41 is reaction tube bayonet socket up and down, 51 bayonet sockets that match for reaction tube bayonet socket up and down.
Embodiment
The device of the centralized procurement sample reaction one in the present embodiment, as shown in Figure 1, it is by the last reaction tube 1 of test tube shape, descends connecting pipe 3 these three parts of reaction tube 2 and hollow to constitute, wherein, connecting pipe 3 is by towards sampler 7 jacks of last reaction tube 1, towards water dropper 32, the middle interconnecting piece position 33 of reaction tube 2 are formed down, the centre has the solid section 31 of sampler 7 jacks, has some apertures 34 of hollow around sampler 7 jacks and communicate with water dropper 32 (seeing Fig. 3, Fig. 3 A, Fig. 3 B for details).Sampler 7 in the present embodiment is a cotton swab.
Connecting pipe 3 is used for last reaction tube 1 and following reaction tube 2 are communicated with, the two ends nozzle diameter of connecting pipe 3 is more smaller than last reaction tube 1 and following reaction tube 2, common little 1-5mm, connecting pipe 3 center section diameters are the same big with last reaction tube 1 and following reaction tube 2 diameters, can be inserted on the connecting pipe 3 with following reaction tube 2 so that go up reaction tube 1.
The one end sealing of last reaction tube 1 and following reaction tube 2, other end opening, openend at last reaction tube 1 and following reaction tube 2 is equipped with screw socket 4 (as shown in Figure 2) or other structure that is used to be connected, be respectively equipped with screw thread 5 (as shown in Figure 4) or other structure that is used to connect at the two ends up and down of connecting pipe 3, this screw thread 5 is supporting with the screw socket 4 of last reaction tube 1 and following reaction tube 2.Last reaction tube 1 and following reaction tube 2 are by after its screw socket 4 (or other structure that is used to be connected) and connecting pipe 3 combinations, and this device is obturator.
Be equipped with at the blind end of last reaction tube 1 and can break device 8 (as rupturable soft shell capsule dress thing), in can breaking device 8, fill reactant liquor (with the reactant liquor that matches in the immunochromatography reagent bar detection method).Cotton swab sampler 7 (sampling head is near last reaction tube 1 blind end, with can break device 8 horizontal levels intersect) is housed in the upper end of connecting pipe 3, and the end portion of connecting pipe 3 has a water dropper 32.
The embedded pipe 9 that inscribe is housed in following reaction tube 2 (is mainly and prevents that reactant liquor from contacting with the adsorptive pads of the upper end of reaction reagent bar 6, and fixation reaction reagent strip 6 is vertical), embedded pipe 9 is the triangular column body structure of hollow, equal up and down opening, its length greater than reaction reagent bar 6 length less than following reaction tube 2, and with the difference of following reaction tube 2 length less than reaction reagent bar 6 length, embedded pipe 9 lower open ends are near reaction tube 2 blind ends down.
In the space of following reaction tube 2 blind ends and embedded pipe 9, reaction reagent bar 6 is housed, this reaction reagent bar 6 is conventional immunochromatography reagent bars, it is by base plate, nitrocellulose membrane, thieving paper, glass fibre membrane and solid-state developer are formed, be provided with test section and Quality Control district successively by the chromatography direction on the nitrocellulose membrane, be fixed with on the test section and the corresponding reaction reagent of detection, the Quality Control district is fixed with and the corresponding quality control reagent of developer, wherein, reaction reagent bar 6 upper ends are that adsorptive pads plays drainage, and the lower end is that glass fibre membrane works to draw reactant liquor and stores collaurum.Reaction reagent bar 6 reaction visible face orientating reaction pipe 2 outsides (promptly towards the observer), and sample application zone one end is downwards near following reaction tube 2 blind ends.Reaction reagent bar 6 can for example in the present embodiment, can be adorned the 1-3 bar according to embedded pipe 9 shapes and the testing requirements different bar numbers of packing into.
During use, outward winding as shown in Figure 1 and go up reaction tube 1 and connecting pipe 3, take out sampler 7 (cotton swab), then sampling.After sampling finishes, will go up reaction tube 1 inversion (going up reaction tube 1 openend upwards), screw the screw socket 4 of reaction tube 1 and the screw thread 5 of connecting pipe 3, squeeze to break and can break device 8, sample and reactant liquor on the sampling head are fully reacted, hold up reaction unit.Reactant liquor splashes into water dropper 32 by some hollow apertures 34 that connecting pipe 3 communicates with water dropper 32 around sampler 7 jacks, splash into embedded pipe 9 internal diameters again, splash into down the blind end of reaction tube 2 again along the internal diameter of embedded pipe 9, react with the collaurum that stores on the reaction reagent bar 6 lower end glass fibre membranes of following reaction tube 2 blind ends.
The device of the centralized procurement sample reaction one in the present embodiment, identical with the device among the embodiment 1, but change the sampler among the embodiment 17 (cotton swab) into the sampling swab, the openend of last reaction tube 1 and following reaction tube 2 all changes reaction tube bayonet socket 41 up and down into, screw thread 5 changes the bayonet socket 51 that matches with reaction tube bayonet socket up and down into, embedded pipe 9 changes the square column structure into hollow into, specifically shown in Fig. 5,5A, 6,7,7A, 7B, 8.Reaction reagent bar 6 in the present embodiment can be adorned the 1-4 bar.
During use, unplug reaction tube 1 and connecting pipe 3 as shown in Figure 5, take out swab sampler 7, then sampling.After sampling finishes, will go up reaction tube 1 and be inverted, be locked and go up reaction tube 1 and connecting pipe 3, squeeze to break and can break device 8, sample and reactant liquor on the sampling head are fully reacted, hold up reaction unit.Reactant liquor splashes into water dropper 32 by some hollow apertures 34 that connecting pipe 3 communicates with water dropper 32 around sampler 7 jacks, splash into embedded pipe 9 internal diameters again, splash into down the blind end of reaction tube 2 again along the internal diameter of embedded pipe 9, react with the collaurum that stores on the reaction reagent bar 6 lower end glass fibre membranes of following reaction tube 2 blind ends.
The device of the centralized procurement sample reaction one in the present embodiment, identical with the device among the embodiment 1, but change the sampler among the embodiment 17 into the spiral sampling head, reaction reagent bar 6 has changed the conventional ight soil detectable bar of occulting blood into, correspondingly, can break reactant liquor in the device 8 has also changed into to occult blood with ight soil and has detected the reactant liquor that matches.
Utilize this device to carry out ight soil and occult blood when testing, use step as embodiment 1.
Claims (9)
1. the device of centralized procurement sample reaction one is characterized in that: comprise reaction tube and following reaction tube, described about reaction tube connect by intermediate connecting part;
Described going up is provided with the broken device that fills reactant liquor in the reaction tube;
How much rod structures of hollow inscribe are set in the described reaction tube down, in the slit of geometry post and following reaction outer tube inscribe, the reaction reagent bar are set;
Described intermediate connecting part connects sampler towards last reaction tube one end, towards following reaction tube one end emitter structure is set.
2. the device of centralized procurement sample reaction one as claimed in claim 1 is characterized in that: described reaction tube up and down is the test tube shape structure of end sealing, an end opening, and reaction tube is connected with the two ends of intermediate connecting part by the syndeton of openend up and down.
3. the device of centralized procurement sample reaction one as claimed in claim 2, it is characterized in that: described syndeton comprises screw socket, bayonet socket.
4. the device of centralized procurement sample as claimed in claim 1 reaction one is characterized in that: the described device that breaks is arranged at blind end near last reaction tube.
5. the device of centralized procurement sample as claimed in claim 1 reaction one, it is characterized in that: the junction of described sampler and intermediate connecting part is a closed construction, the structure that leads in being designed to around the sampler junction also communicates with emitter structure.
6. as the device of claim 1 or 5 described centralized procurement samples reaction one, it is characterized in that: described sampler comprises sampling swab, spiral sampling head or cotton swab, and its sampling head is near last reaction tube blind end, and can break the device horizontal level and intersects.
7. the device of centralized procurement sample reaction one as claimed in claim 1 is characterized in that: the two-port diameter ratio of described intermediate connecting part is the little 1-5mm of reaction tube up and down, and the mesozone diameter of intermediate connecting part equals reaction tube diameter up and down.
8. the device of centralized procurement sample reaction one as claimed in claim 1, it is characterized in that: described how much posts are interchangeable how much posts, equal up and down opening, its length greater than the reaction reagent bar less than following reaction tube, and with the difference of following tube length of reaction tube less than reaction reagent bar length, how much close reaction tube blind ends down of post one end, geometric configuration comprises triangle, square.
9. the device of centralized procurement sample reaction one as claimed in claim 1, it is characterized in that: described reaction reagent bar comprises immunochromatography reagent bar, the ight soil detectable bar of occulting blood, the reaction surface of this reaction reagent bar is towards the observer, and the sample application zone of reaction reagent bar is near the blind end of following reaction tube.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN2009200741639U CN201555723U (en) | 2009-06-25 | 2009-06-25 | Device integrating sampling and reacting |
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CN2009200741639U CN201555723U (en) | 2009-06-25 | 2009-06-25 | Device integrating sampling and reacting |
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CN2009200741639U Expired - Lifetime CN201555723U (en) | 2009-06-25 | 2009-06-25 | Device integrating sampling and reacting |
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Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103175965A (en) * | 2011-12-20 | 2013-06-26 | 安徽深蓝医疗科技有限公司 | Fecal occult blood detection kit and preparation method |
CN103185789A (en) * | 2011-12-27 | 2013-07-03 | 深圳市爱速尔生物技术有限公司 | RV-ADV antigen feces rapid detector |
CN104792567A (en) * | 2015-04-30 | 2015-07-22 | 珠海市银科医学工程有限公司 | Novel excrement sampling and rapid immune detection device and operation method thereof |
WO2016188362A1 (en) * | 2015-05-28 | 2016-12-01 | 万华普曼生物工程有限公司 | Collection and detection integrated device with mis-assembling prevention structure |
CN109187959A (en) * | 2018-08-27 | 2019-01-11 | 刘小玲 | It is a kind of personal from survey chromatography agent detection devices |
CN110389057A (en) * | 2018-04-23 | 2019-10-29 | 上海伯顿医疗设备有限公司 | Integrated multi-functional biological sample processor |
CN115267175A (en) * | 2022-07-05 | 2022-11-01 | 杭州莱和生物技术有限公司 | Integrated medical detector |
WO2024001406A1 (en) * | 2022-06-30 | 2024-01-04 | 江苏硕世生物科技股份有限公司 | Sampling detection device |
-
2009
- 2009-06-25 CN CN2009200741639U patent/CN201555723U/en not_active Expired - Lifetime
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103175965A (en) * | 2011-12-20 | 2013-06-26 | 安徽深蓝医疗科技有限公司 | Fecal occult blood detection kit and preparation method |
CN103185789A (en) * | 2011-12-27 | 2013-07-03 | 深圳市爱速尔生物技术有限公司 | RV-ADV antigen feces rapid detector |
CN104792567A (en) * | 2015-04-30 | 2015-07-22 | 珠海市银科医学工程有限公司 | Novel excrement sampling and rapid immune detection device and operation method thereof |
WO2016188362A1 (en) * | 2015-05-28 | 2016-12-01 | 万华普曼生物工程有限公司 | Collection and detection integrated device with mis-assembling prevention structure |
US10384205B2 (en) | 2015-05-28 | 2019-08-20 | W.H.P.M. Bioresearch and Technology Co., Ltd. | Integrated sampling and detection device with misassembly prevention structure |
CN110389057A (en) * | 2018-04-23 | 2019-10-29 | 上海伯顿医疗设备有限公司 | Integrated multi-functional biological sample processor |
CN109187959A (en) * | 2018-08-27 | 2019-01-11 | 刘小玲 | It is a kind of personal from survey chromatography agent detection devices |
WO2024001406A1 (en) * | 2022-06-30 | 2024-01-04 | 江苏硕世生物科技股份有限公司 | Sampling detection device |
CN115267175A (en) * | 2022-07-05 | 2022-11-01 | 杭州莱和生物技术有限公司 | Integrated medical detector |
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Granted publication date: 20100818 |
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