ITRM20080342A1 - Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso. - Google Patents

Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.

Info

Publication number
ITRM20080342A1
ITRM20080342A1 IT000342A ITRM20080342A ITRM20080342A1 IT RM20080342 A1 ITRM20080342 A1 IT RM20080342A1 IT 000342 A IT000342 A IT 000342A IT RM20080342 A ITRM20080342 A IT RM20080342A IT RM20080342 A1 ITRM20080342 A1 IT RM20080342A1
Authority
IT
Italy
Prior art keywords
dolls
insulation
use methods
pulp cells
similar pulp
Prior art date
Application number
IT000342A
Other languages
English (en)
Italian (it)
Inventor
Federico Ferro
Original Assignee
Univ Degli Studi Udine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Udine filed Critical Univ Degli Studi Udine
Priority to IT000342A priority Critical patent/ITRM20080342A1/it
Priority to US13/000,344 priority patent/US20110158962A1/en
Priority to EP09769343A priority patent/EP2313493A1/en
Priority to CN2009801335654A priority patent/CN102131918A/zh
Priority to PCT/EP2009/058015 priority patent/WO2009156495A1/en
Priority to JP2011515396A priority patent/JP2011525798A/ja
Publication of ITRM20080342A1 publication Critical patent/ITRM20080342A1/it
Priority to US15/046,306 priority patent/US10421947B2/en

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    • CCHEMISTRY; METALLURGY
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    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0664Dental pulp stem cells, Dental follicle stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
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    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/36Lipids
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/38Vitamins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/105Insulin-like growth factors [IGF]
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/11Epidermal growth factor [EGF]
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/119Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
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    • C12N2501/135Platelet-derived growth factor [PDGF]
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/39Steroid hormones
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999Small molecules not provided for elsewhere

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
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  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT000342A 2008-06-26 2008-06-26 Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso. ITRM20080342A1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT000342A ITRM20080342A1 (it) 2008-06-26 2008-06-26 Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.
US13/000,344 US20110158962A1 (en) 2008-06-26 2009-06-26 Dental pulp marrow similar cells (dpmsc) and methods of isolating and using
EP09769343A EP2313493A1 (en) 2008-06-26 2009-06-26 Dental pulp marrow similar cells (dpmsc) and methods of isolating and using
CN2009801335654A CN102131918A (zh) 2008-06-26 2009-06-26 牙髓髓相似细胞(dpmsc)和分离和使用的方法
PCT/EP2009/058015 WO2009156495A1 (en) 2008-06-26 2009-06-26 Dental pulp marrow similar cells (dpmsc) and methods of isolating and using
JP2011515396A JP2011525798A (ja) 2008-06-26 2009-06-26 歯髄類似細胞(dpmsc)ならびにその単離および使用の方法
US15/046,306 US10421947B2 (en) 2008-06-26 2016-02-17 Dental pulp marrow similar cells (DPMSC) and methods of isolating and using

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000342A ITRM20080342A1 (it) 2008-06-26 2008-06-26 Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.

Publications (1)

Publication Number Publication Date
ITRM20080342A1 true ITRM20080342A1 (it) 2009-12-27

Family

ID=40302081

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000342A ITRM20080342A1 (it) 2008-06-26 2008-06-26 Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.

Country Status (6)

Country Link
US (2) US20110158962A1 (https=)
EP (1) EP2313493A1 (https=)
JP (1) JP2011525798A (https=)
CN (1) CN102131918A (https=)
IT (1) ITRM20080342A1 (https=)
WO (1) WO2009156495A1 (https=)

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* Cited by examiner, † Cited by third party
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ITRM20080342A1 (it) 2008-06-26 2009-12-27 Univ Degli Studi Udine Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.
US20150335400A1 (en) * 2009-06-17 2015-11-26 The Trustees Of Columbia University In The City Of New York Tooth scaffolds
US9550975B2 (en) * 2009-07-15 2017-01-24 Mari Dezawa SSEA-3 pluripotent stem cell isolated from body tissue
ES2360434B1 (es) 2009-07-21 2012-04-12 Universitat Internacional De Catalunya Celulas madre pluripotenciales obtenidas a partir de la pulpa dental.
JP5608927B2 (ja) * 2010-04-13 2014-10-22 国立大学法人名古屋大学 歯髄幹細胞を用いた神経疾患治療用組成物
US9719068B2 (en) 2010-05-06 2017-08-01 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
EP2633870B1 (en) * 2012-02-29 2018-08-01 Technische Universität Berlin Method of preparing an artificial tooth primordium in vitro and artificial tooth primordium derived therefrom
WO2013131012A1 (en) * 2012-03-01 2013-09-06 University Of Miami Isolation and use of pluripotent stem cell population from adult neural crest-derived tissues
JP6193214B2 (ja) 2012-03-29 2017-09-06 Jcrファーマ株式会社 歯髄由来の多能性幹細胞の製造方法
US10709741B2 (en) 2013-02-13 2020-07-14 National University Corporation Nagoya University Composition for preventing or treating inflammatory disease
US9790468B2 (en) 2013-03-15 2017-10-17 Avita Iinternational Ltd. Multifunctional immature dental pulp stem cells and therapeutic applications
US11207352B2 (en) 2013-03-15 2021-12-28 Avita International Ltd. Compositions comprising stem cells expressing mesenchymal and neuronal markers and uses thereof to treat neurological disease
US11306290B2 (en) 2013-03-15 2022-04-19 Avita International Ltd. Stem cells expressing mesenchymal and neuronal markers, compositions thereof, and methods of preparation thereof
US11278574B2 (en) * 2013-03-15 2022-03-22 Avita International Ltd. Use of stem cells expressing mesenchymal and neuronal markers and compositions thereof to treat neurological disease
WO2017153956A1 (en) * 2016-03-09 2017-09-14 Avita International Ltd. Uses of dental pulp stem cells expressing mesenchymal and neuronal markers and compositions thereof to treat neurological disease
CN106661548B (zh) 2014-05-28 2020-12-11 儿童医院医疗中心 用于经由定向分化将前体细胞转化为胃组织的方法和系统
JP6909154B2 (ja) * 2014-08-14 2021-07-28 アヴィタ・インターナショナル・リミテッド 幹細胞組成物および療法適用のための幹細胞を産生する方法
JP6804438B2 (ja) 2014-10-17 2020-12-23 チルドレンズ ホスピタル メディカル センター 多能性幹細胞を使用するヒト小腸のin vivoモデル、並びにそれを作製、及び使用する方法
CN106471371B (zh) * 2014-12-05 2018-05-04 宣捷生物科技股份有限公司 区别间充质干细胞的方法
CN105063089A (zh) * 2015-05-19 2015-11-18 西安交通大学 hTERT重组慢病毒永生化人脱落乳牙牙髓干细胞系的方法
KR102729404B1 (ko) 2016-11-04 2024-11-14 칠드런즈 호스피탈 메디칼 센터 간 유사 장기 조성물 및 이를 제조 및 사용하는 방법
JP7068305B2 (ja) 2016-12-05 2022-05-16 チルドレンズ ホスピタル メディカル センター 結腸オルガノイドならびにその作製方法および使用方法
US20200270579A1 (en) * 2017-02-03 2020-08-27 Kyushu University, National University Corporation Method for preparing dental pulp stem cells from cells derived from dental pulp tissue
US12281334B2 (en) 2017-04-14 2025-04-22 Children's Hospital Medical Center Multi donor stem cell compositions and methods of making same
EP3694603B1 (en) 2017-10-10 2026-04-08 Children's Hospital Medical Center Esophageal tissue and/or organoid compositions and methods of making same
EP3708175A4 (en) * 2017-11-09 2021-07-28 Sapporo Medical University MEDICINAL PRODUCT FOR TISSUE REGENERATION, AND ITS PREPARATION PROCESS
US12379372B2 (en) 2017-12-21 2025-08-05 Children's Hospital Medical Center Digitalized human organoids and methods of using same
KR102887406B1 (ko) 2018-07-26 2025-11-19 칠드런즈 호스피탈 메디칼 센터 간-담도-췌장 조직 및 이를 제조하는 방법
CA3103769A1 (en) * 2018-07-31 2020-02-06 Jcr Pharmaceuticals Co., Ltd. Method for producing dental pulp-derived cells
AU2019339410A1 (en) 2018-09-12 2021-04-15 Children's Hospital Medical Center Organoid compositions for the production of hematopoietic stem cells and derivatives thereof
WO2020160371A1 (en) 2019-02-01 2020-08-06 The University Of Hong Kong Innervated organoid compositions and methods of making same
WO2020243633A1 (en) 2019-05-31 2020-12-03 Children's Hospital Medical Center Shaped organoid compositions and methods of making same
WO2020243613A1 (en) 2019-05-31 2020-12-03 Children's Hospital Medical Center Methods of generating and expanding hematopoietic stem cells
CN114736957B (zh) * 2022-04-15 2024-03-12 中国人民解放军空军军医大学 外泌体介导rna casc15干预阿尔茨海默症突触损失的应用
WO2023227972A1 (en) * 2022-05-24 2023-11-30 Iceta - Instituto De Ciências, Tecnologias E Agroambiente Da Universidade Do Porto Process for preparation and cryopreservation of dental pulp from definitive teeth and products thereof based on isolated mesenchymal stem cells
EP4600350A1 (en) * 2022-10-03 2025-08-13 Kidswell Bio Corporation Novel dental pulp stem cell population
WO2024075145A1 (ja) * 2022-10-03 2024-04-11 キッズウェル・バイオ株式会社 新規な歯髄幹細胞集団
TW202434721A (zh) * 2023-02-14 2024-09-01 國立大學法人山口大學 細胞群、三維細胞培養體、醫藥組成物、胞泌體及製作此細胞群的方法
CN117363565B (zh) * 2023-09-28 2024-05-17 南方医科大学口腔医院 一种用于骨再生的血管化干细胞球的构建方法

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ES2366085T3 (es) 2003-04-19 2011-10-17 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Células madre postnatales y usos de las mismas.
ES2515818T3 (es) * 2003-11-20 2014-10-30 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Células madre multipotentes postnatales de ligamento periodontal humano y sus usos
ITNA20040043A1 (it) * 2004-07-28 2004-10-28 Francesco Carinci Tecnica di ingegneria tissutale ottenibile mediante isolamento di una nuova sottopopolazione di cellule staminali mbp-shed ed mbp-dpsc, isolate da polpa di denti decidui e permanenti in grado di produrre in vitro tessuto osseo umano.
EP1705245B1 (en) 2005-03-23 2009-05-20 Stiftung CAESAR Neural stem cells
US20070258957A1 (en) * 2006-05-04 2007-11-08 Russell Bowermaster Method for obtaining and storing multipotent stem cells
EP1748066B1 (en) * 2005-07-29 2008-12-31 Stiftung CAESAR Method for isolating stem cells from a pad-like tissue of teeth
WO2007117472A2 (en) * 2006-04-07 2007-10-18 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Adult bone marrow cell transplantation to testes creation of transdifferentiated testes germ cells, leydig cells and sertoli cells
KR20090031895A (ko) * 2006-06-09 2009-03-30 안트로제네시스 코포레이션 태반 니치 및 줄기 세포 배양을 위한 이의 용도
ITRM20080342A1 (it) 2008-06-26 2009-12-27 Univ Degli Studi Udine Cellule di polpa dentale midollo-simili, metodi per isolamento ed uso.

Also Published As

Publication number Publication date
JP2011525798A (ja) 2011-09-29
CN102131918A (zh) 2011-07-20
EP2313493A1 (en) 2011-04-27
WO2009156495A1 (en) 2009-12-30
US20160244724A1 (en) 2016-08-25
US10421947B2 (en) 2019-09-24
US20110158962A1 (en) 2011-06-30

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