ITMI911880A1 - Metodo per la preparazione di forme farmaceutiche orali a rilascio prolungato contenenti sostanze attive a solubilita' dipendente dal valore di ph. - Google Patents
Metodo per la preparazione di forme farmaceutiche orali a rilascio prolungato contenenti sostanze attive a solubilita' dipendente dal valore di ph.Info
- Publication number
- ITMI911880A1 ITMI911880A1 IT001880A ITMI911880A ITMI911880A1 IT MI911880 A1 ITMI911880 A1 IT MI911880A1 IT 001880 A IT001880 A IT 001880A IT MI911880 A ITMI911880 A IT MI911880A IT MI911880 A1 ITMI911880 A1 IT MI911880A1
- Authority
- IT
- Italy
- Prior art keywords
- preparation
- value
- active substances
- extended release
- containing active
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI911880A IT1250654B (it) | 1991-07-08 | 1991-07-08 | Metodo per la preparazione di forme farmaceutiche orali a rilascio prolungato contenenti sostanze attive a solubilita' dipendente dal valore di ph. |
AU22293/92A AU2229392A (en) | 1991-07-08 | 1992-07-03 | Method for the preparation of prolonged-release oral pharmaceutical forms containing active substances having a solubility dependent upon the ph value |
PCT/EP1992/001503 WO1993000889A1 (en) | 1991-07-08 | 1992-07-03 | METHOD FOR THE PREPARATION OF PROLONGED-RELEASE ORAL PHARMACEUTICAL FORMS CONTAINING ACTIVE SUBSTANCES HAVING A SOLUBILITY DEPENDENT UPON THE pH VALUE |
CN92111078.2A CN1082888A (zh) | 1991-07-08 | 1992-08-24 | 用于制备包含其溶解性依赖于pH值的活性物质的缓释口服药物剂型的方法 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI911880A IT1250654B (it) | 1991-07-08 | 1991-07-08 | Metodo per la preparazione di forme farmaceutiche orali a rilascio prolungato contenenti sostanze attive a solubilita' dipendente dal valore di ph. |
CN92111078.2A CN1082888A (zh) | 1991-07-08 | 1992-08-24 | 用于制备包含其溶解性依赖于pH值的活性物质的缓释口服药物剂型的方法 |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI911880A0 ITMI911880A0 (it) | 1991-07-08 |
ITMI911880A1 true ITMI911880A1 (it) | 1993-01-08 |
IT1250654B IT1250654B (it) | 1995-04-21 |
Family
ID=36790863
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI911880A IT1250654B (it) | 1991-07-08 | 1991-07-08 | Metodo per la preparazione di forme farmaceutiche orali a rilascio prolungato contenenti sostanze attive a solubilita' dipendente dal valore di ph. |
Country Status (4)
Country | Link |
---|---|
CN (1) | CN1082888A (it) |
AU (1) | AU2229392A (it) |
IT (1) | IT1250654B (it) |
WO (1) | WO1993000889A1 (it) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4406424A1 (de) | 1994-02-28 | 1995-08-31 | Bayer Ag | Expandierbare Arzneiformen |
WO1999047073A1 (en) * | 1998-03-19 | 1999-09-23 | Merck & Co., Inc. | Liquid polymeric compositions for controlled release of bioactive substances |
EP1027885B1 (en) * | 1999-02-09 | 2008-07-09 | Pfizer Products Inc. | Basic drug compositions with enhanced bioavailability |
DE60039379D1 (de) * | 1999-02-10 | 2008-08-21 | Pfizer Prod Inc | Pharmazeutische feste Dispersionen |
ATE404178T1 (de) * | 1999-02-10 | 2008-08-15 | Pfizer Prod Inc | Vorrichtung mit matrixgesteuerter wirkstofffreisetzung |
US8895064B2 (en) | 1999-06-14 | 2014-11-25 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
PT1183014E (pt) | 1999-06-14 | 2003-12-31 | Cosmo Spa | Composicoes farmaceuticas orais de libertacao controlada e de dissimulacao de sabor |
KR100540035B1 (ko) * | 2002-02-01 | 2005-12-29 | 주식회사 태평양 | 다단계 경구 약물 방출 제어 시스템 |
EP1591107A1 (en) * | 2004-04-28 | 2005-11-02 | Pfizer GmbH Arzneimittelwerk Gödecke | Process for the selective increase of a release rate of an active material from a pharmaceutical composition |
US20070092559A1 (en) * | 2005-10-24 | 2007-04-26 | Jinghua Yuan | Liquid dosage forms having enteric properties of delayed and then sustained release |
ES2348157T3 (es) * | 2006-12-15 | 2010-11-30 | Campina Nederland Holding B.V. | Excipiente de liberación modificada y su uso. |
US10154964B2 (en) | 2011-09-07 | 2018-12-18 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
KR102505099B1 (ko) * | 2019-03-28 | 2023-03-03 | 농업회사법인 보길바이오 주식회사 | 생체고분자 분자구조의 꼬임 및 풀림을 이용한 미세물질 포집 방법 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1467781A1 (de) * | 1963-07-15 | 1968-12-05 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von Dragees mit verlaengerter Wirkstofffreigabe |
LU85058A1 (fr) * | 1983-10-24 | 1985-06-19 | Pharlyse | Comprimes pharmaceutiques a liberation prolongee,leur preparation et leur utilisation |
JPS6124516A (ja) * | 1984-07-12 | 1986-02-03 | Fujisawa Pharmaceut Co Ltd | 持続性錠剤 |
JPS6248618A (ja) * | 1985-08-27 | 1987-03-03 | Zeria Shinyaku Kogyo Kk | 徐放性製剤およびその製造法 |
DE3769707D1 (de) * | 1986-06-17 | 1991-06-06 | Recordati Chem Pharm | Therapeutisches system mit geregelter wirkstoffabgabe. |
GB8626098D0 (en) * | 1986-10-31 | 1986-12-03 | Euro Celtique Sa | Controlled release hydromorphone composition |
ZA881301B (en) * | 1987-02-27 | 1989-10-25 | Lilly Co Eli | Sustained release matrix formulations |
-
1991
- 1991-07-08 IT ITMI911880A patent/IT1250654B/it active IP Right Grant
-
1992
- 1992-07-03 WO PCT/EP1992/001503 patent/WO1993000889A1/en active Application Filing
- 1992-07-03 AU AU22293/92A patent/AU2229392A/en not_active Abandoned
- 1992-08-24 CN CN92111078.2A patent/CN1082888A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
IT1250654B (it) | 1995-04-21 |
CN1082888A (zh) | 1994-03-02 |
WO1993000889A1 (en) | 1993-01-21 |
ITMI911880A0 (it) | 1991-07-08 |
AU2229392A (en) | 1993-02-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19950728 |