ITMI911767A0 - Anticorpi policlonali anti-irudina e loro utilizzo per la identificazione, l'immunopurificazione e la determinazione quantitativa dell'irudina - Google Patents
Anticorpi policlonali anti-irudina e loro utilizzo per la identificazione, l'immunopurificazione e la determinazione quantitativa dell'irudinaInfo
- Publication number
- ITMI911767A0 ITMI911767A0 IT91MI1767A ITMI911767A ITMI911767A0 IT MI911767 A0 ITMI911767 A0 IT MI911767A0 IT 91MI1767 A IT91MI1767 A IT 91MI1767A IT MI911767 A ITMI911767 A IT MI911767A IT MI911767 A0 ITMI911767 A0 IT MI911767A0
- Authority
- IT
- Italy
- Prior art keywords
- hirudin
- immunopurification
- identification
- quantitative determination
- antibodies
- Prior art date
Links
- 229940006607 hirudin Drugs 0.000 title 2
- 102000007625 Hirudins Human genes 0.000 title 1
- 108010007267 Hirudins Proteins 0.000 title 1
- WQPDUTSPKFMPDP-OUMQNGNKSA-N hirudin Chemical compound C([C@@H](C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC(OS(O)(=O)=O)=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]1NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@H](C(NCC(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N2)=O)CSSC1)C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=2C=CC(O)=CC=2)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)C(C)C)[C@@H](C)O)CSSC1)C(C)C)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 WQPDUTSPKFMPDP-OUMQNGNKSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI911767A IT1248565B (it) | 1991-06-27 | 1991-06-27 | Anticorpi policlonali anti-irudina e loro utilizzo per la identificazione, l`immunopurificazione e la determinazione quantitativa dell`uridina. |
| MX9203242A MX9203242A (es) | 1991-06-27 | 1992-06-24 | Anticuerpos policlonales anti-hirudin y metodo para su produccion. |
| PCT/EP1992/001448 WO1993000363A1 (en) | 1991-06-27 | 1992-06-26 | Anti-hirudin polyclonal antibodies and their use for the identification, immunopurification and quantitative determination of hirudin |
| ES92914181T ES2107545T3 (es) | 1991-06-27 | 1992-06-26 | Anticuerpos policlonales dirigidos contra la hirudina y su utilizacion para la identificacion, la purificacion inmunologica y la determinacion cuantitativa de la hirudina. |
| EP92914181A EP0600901B1 (en) | 1991-06-27 | 1992-06-26 | Anti-hirudin polyclonal antibodies and their use for the identification, immunopurification and quantitative determination of hirudin |
| EP19920110856 EP0520502A3 (en) | 1991-06-27 | 1992-06-26 | Anti-hirudin polyclonal antibodies and their use for the identification, immunopurification and quantitative determination of hirudin |
| JP5501337A JPH06509070A (ja) | 1991-06-27 | 1992-06-26 | 抗ヒルジンポリクローナル抗体ならびにヒルジンの同定、免疫精製および定量的測定のためのその用途 |
| DE69221882T DE69221882T2 (de) | 1991-06-27 | 1992-06-26 | Polyklonale anti-hirudin antikörper und ihre verwendung in der identifizierung und quantitativen bestimmung von hirudin |
| AU21937/92A AU2193792A (en) | 1991-06-27 | 1992-06-26 | Anti-hirudin polyclonal antibodies and their use for the identification, immunopurification and quantitative determination of hirudin |
| ZA924773A ZA924773B (en) | 1991-06-27 | 1992-06-26 | Anti-hirudin polyclonal antibodies and their use for the identification,immunopurification and quantitative determination of hirudin |
| NZ243355A NZ243355A (en) | 1991-06-27 | 1992-06-29 | Hirudin or hirudin-like protein polymer immunogen and its use in raising antibodies against hirudin |
| IE208192A IE922081A1 (en) | 1991-06-27 | 1992-07-01 | Anti-hirudin polyclonal antibodies and their use for the¹identification, immunopurification and quantitative¹determination of hirudin |
| US08/603,182 US6719975B1 (en) | 1991-06-27 | 1996-02-20 | Anti-hirudin polyclonal antibodies and their use for the identification, immunopurification and quantitative determination of hirudin |
| US10/767,200 US20050095685A1 (en) | 1991-06-27 | 2004-01-30 | Anti-hirudin polyclonal antibodies and their use for the identification, immunopurification and quantitative determination of hirudin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI911767A IT1248565B (it) | 1991-06-27 | 1991-06-27 | Anticorpi policlonali anti-irudina e loro utilizzo per la identificazione, l`immunopurificazione e la determinazione quantitativa dell`uridina. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI911767A0 true ITMI911767A0 (it) | 1991-06-27 |
| ITMI911767A1 ITMI911767A1 (it) | 1992-12-27 |
| IT1248565B IT1248565B (it) | 1995-01-19 |
Family
ID=11360217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI911767A IT1248565B (it) | 1991-06-27 | 1991-06-27 | Anticorpi policlonali anti-irudina e loro utilizzo per la identificazione, l`immunopurificazione e la determinazione quantitativa dell`uridina. |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP0600901B1 (it) |
| JP (1) | JPH06509070A (it) |
| AU (1) | AU2193792A (it) |
| DE (1) | DE69221882T2 (it) |
| ES (1) | ES2107545T3 (it) |
| IE (1) | IE922081A1 (it) |
| IT (1) | IT1248565B (it) |
| MX (1) | MX9203242A (it) |
| NZ (1) | NZ243355A (it) |
| WO (1) | WO1993000363A1 (it) |
| ZA (1) | ZA924773B (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1266561B1 (it) * | 1993-07-22 | 1997-01-09 | Mini Ricerca Scient Tecnolog | Analoghi di un polipeptide anti-trombinico e procedimento per la loro preparazione |
| US5661001A (en) * | 1993-08-04 | 1997-08-26 | Ciba-Geigy Corporation | High molecular weight desulphatohirudin |
| US5710413A (en) * | 1995-03-29 | 1998-01-20 | Minnesota Mining And Manufacturing Company | H-field electromagnetic heating system for fusion bonding |
| CN115572329B (zh) * | 2021-06-21 | 2024-02-06 | 王大勇 | 一组活性增强代谢较慢的菲牛蛭基因重组水蛭素及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU554859B2 (en) * | 1981-09-04 | 1986-09-04 | Regents Of The University Of California, The | Polymerized albumin vaccine |
| EP0380443B2 (en) * | 1989-01-25 | 1999-06-30 | Novartis AG | Monoclonal antibodies specific for thrombin hirudin |
-
1991
- 1991-06-27 IT ITMI911767A patent/IT1248565B/it active IP Right Grant
-
1992
- 1992-06-24 MX MX9203242A patent/MX9203242A/es unknown
- 1992-06-26 JP JP5501337A patent/JPH06509070A/ja active Pending
- 1992-06-26 AU AU21937/92A patent/AU2193792A/en not_active Abandoned
- 1992-06-26 EP EP92914181A patent/EP0600901B1/en not_active Expired - Lifetime
- 1992-06-26 WO PCT/EP1992/001448 patent/WO1993000363A1/en active IP Right Grant
- 1992-06-26 EP EP19920110856 patent/EP0520502A3/en not_active Withdrawn
- 1992-06-26 DE DE69221882T patent/DE69221882T2/de not_active Expired - Fee Related
- 1992-06-26 ZA ZA924773A patent/ZA924773B/xx unknown
- 1992-06-26 ES ES92914181T patent/ES2107545T3/es not_active Expired - Lifetime
- 1992-06-29 NZ NZ243355A patent/NZ243355A/xx unknown
- 1992-07-01 IE IE208192A patent/IE922081A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MX9203242A (es) | 1994-04-29 |
| NZ243355A (en) | 1993-09-27 |
| DE69221882D1 (de) | 1997-10-02 |
| EP0600901B1 (en) | 1997-08-27 |
| ES2107545T3 (es) | 1997-12-01 |
| DE69221882T2 (de) | 1998-01-02 |
| ZA924773B (en) | 1993-03-31 |
| AU2193792A (en) | 1993-01-25 |
| IE922081A1 (en) | 1992-12-30 |
| EP0520502A3 (en) | 1993-06-23 |
| EP0520502A2 (en) | 1992-12-30 |
| IT1248565B (it) | 1995-01-19 |
| WO1993000363A1 (en) | 1993-01-07 |
| ITMI911767A1 (it) | 1992-12-27 |
| JPH06509070A (ja) | 1994-10-13 |
| EP0600901A1 (en) | 1994-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970527 |