ITMI20090967A1 - COMPOSITION FOR A NATURAL FOOD SUPPLEMENT, PARTICULARLY TO ENCOURAGE THE PHYSIOLOGICAL FUNCTIONALITY OF THE LIVER. - Google Patents

COMPOSITION FOR A NATURAL FOOD SUPPLEMENT, PARTICULARLY TO ENCOURAGE THE PHYSIOLOGICAL FUNCTIONALITY OF THE LIVER. Download PDF

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Publication number
ITMI20090967A1
ITMI20090967A1 IT000967A ITMI20090967A ITMI20090967A1 IT MI20090967 A1 ITMI20090967 A1 IT MI20090967A1 IT 000967 A IT000967 A IT 000967A IT MI20090967 A ITMI20090967 A IT MI20090967A IT MI20090967 A1 ITMI20090967 A1 IT MI20090967A1
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IT
Italy
Prior art keywords
composition
tit
vitamin
liver
fillanto
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IT000967A
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Italian (it)
Inventor
Marilena Mauriello
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Forem Pharma S R L
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A23L1/3002
    • A23L1/308
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)

Description

"COMPOSIZIONE PER UN INTEGRATORE NATURALE ALI-MENTARE, PARTICOLARMENTE PER FAVORIRE LA FISIO-LOGICA FUNZIONALITÀ DEL FEGATO" "COMPOSITION FOR A NATURAL ALI-MENTARY SUPPLEMENT, PARTICULARLY TO FAVOR THE PHYSIO-LOGIC FUNCTIONALITY OF THE LIVER"

D E S C R I Z I O N E DESCRIPTION

Il presente trovato ha come oggetto una composizione per un integratore naturale alimentare, particolarmente per favorire la fisiologica funzionalità del fegato. The present invention relates to a composition for a natural food supplement, particularly for promoting the physiological functionality of the liver.

Compito del presente trovato à ̈ quello di realizzare una composizione in grado di svolgere un’importante azione epatoprotettrice. The aim of the present invention is to provide a composition capable of carrying out an important hepatoprotective action.

Nell’ambito di questo compito, uno scopo del trovato à ̈ quello di realizzare una composizione che favorisca i processi di rigenerazione degli epatociti. Within the scope of this aim, an object of the invention is to provide a composition which favors the regeneration processes of hepatocytes.

Un ulteriore scopo del presente trovato à ̈ quello di realizzare una composizione in grado di favorire i processi di detossificazione del fegato, e che aiuti ad inibire la perossidazione lipidica. A further object of the present invention is to provide a composition capable of favoring the detoxification processes of the liver, and which helps to inhibit lipid peroxidation.

Questo ed altri scopi, che meglio appariranno evidenziati in seguito, sono raggiunti da una composizione per un integratore naturale alimentare, particolarmente per favorire la fisiologica funzionalità del fegato, caratterizzata dal fatto di comprendere, in combinazione, le seguenti sostanze: Silimarina, Inulina, Acido Clorogenico e Fillanto Amaro. This and other purposes, which will be better highlighted later, are achieved by a composition for a natural food supplement, particularly to promote the physiological functionality of the liver, characterized by the fact of including, in combination, the following substances: Silymarin, Inulin, Acid Chlorogenic and Fillanto Amaro.

La Silimarina, che à ̈ la componente attiva dell’estratto di Cardo Mariano, svolge un’azione epatoprotettiva ed accelera il processo di rigenerazione del fegato, in quanto aumenta l’attività metabolica delle cellule epatiche. Silymarin, which is the active component of Milk Thistle extract, performs a hepatoprotective action and accelerates the regeneration process of the liver, as it increases the metabolic activity of the liver cells.

L’Inulina à ̈ la componente attiva dell’estratto di Tarassaco, e favorisce il riequilibrio della flora intestinale potenziandone l’attività. Inulin is the active component of Dandelion extract, and promotes the rebalancing of the intestinal flora by enhancing its activity.

L’Acido Clorogenico, che à ̈ la componente attiva del carciofo, incrementa la funzionalità epatica e biliare. Chlorogenic acid, which is the active component of the artichoke, increases liver and biliary function.

L’Acido Clorogenico favorisce inoltre il metabolismo lipidico aumentando l’escrezione di colesterolo, e svolge un’azione antiossidante. Chlorogenic acid also promotes lipid metabolism by increasing the excretion of cholesterol, and has an antioxidant action.

Una composizione preferita secondo l'invenzione comprende i seguenti componenti: A preferred composition according to the invention comprises the following components:

- fruttosio; - fructose;

- acido tartarico; - tartaric acid;

- sodio bicarbonato; - sodium bicarbonate;

- L-taurina; - L-taurine;

- acidificanti: acido citrico, acido malico; - acidifiers: citric acid, malic acid;

- fillanto e.s. fiori e foglie tit. 15% tannini (Phyllantus niruri) (40 mg); - fillanto e.s. flowers and leaves tit. 15% tannins (Phyllantus niruri) (40 mg);

- carciofo e.s. foglia tit. 2,5% acido clorogenico (Cynara scolymus L.) (40 mg); - artichoke d.e. leaf tit. 2.5% chlorogenic acid (Cynara scolymus L.) (40 mg);

- tarassaco e.s. e.s. radice tit. 2,0% Inulina (Taraxacuni officinale weber) (40 mg); - dandelion dry extract e.s. root tit. 2.0% Inulin (Taraxacuni officinale weber) (40 mg);

- antiagglomerante: biossido di silicio; - anti-caking agent: silicon dioxide;

- cardo mariano e.s. frutti tit. 2,0% Silimarina (Silybum marianum gaertner) (25 mg); - milk thistle dry extract fruit tit. 2.0% Silymarin (Silybum marianum gaertner) (25 mg);

- edulcorante: acesulfame potassico; - sweetener: acesulfame potassium;

- aroma; - aroma;

- vitamina PP; - vitamin PP;

- vitamina B6 cloridrato. - vitamin B6 hydrochloride.

La composizione à ̈ vantaggiosamente utilizzata per realizzare un integratore in polvere confezionato in bustine. The composition is advantageously used to make a powder supplement packaged in sachets.

L'esempio realizzativo della composizione, descritto sopra, presenta i seguenti valori nutrizionali, riferiti al contenuto di una bustina, di 100 g di prodotto e di % RDA (Recommended Daily Allowance): The example of the composition, described above, has the following nutritional values, referred to the content of a sachet, of 100 g of product and% RDA (Recommended Daily Allowance):

ANALISI MEDIA Per 1 bustina Per 100 g % RDA per Bst VitaminaPP mg 9,0 180,0 50 VitarninaB6 mg 1,0 20,0 50 Fillanto mg 40,0 800,0 AVERAGE ANALYSIS For 1 sachet For 100 g% RDA for Bst VitaminPP mg 9.0 180.0 50 VitarninaB6 mg 1.0 20.0 50 Phyllant mg 40.0 800.0

Carciofo mg 40,0 800,0 Artichoke mg 40.0 800.0

Tarassaco mg 40,0 800,0 Dandelion mg 40.0 800.0

Cardomariano mg 25,0 500,0 Cardomarian 25.0 mg 500.0

Tali percentuali possono variare del ± 30%. These percentages may vary by ± 30%.

Si à ̈ in pratica constatato che il trovato raggiunge il compito e gli scopi prefissati. In practice it has been found that the invention achieves the intended aim and objects.

Claims (3)

RIVENDICAZIONI 1. Composizione per un integratore naturale alimentare per favorire la fisiologica funzionalità del fegato, caratterizzata dal fatto di comprendere in combinazione sinergica le sostanze: Silimarina, Inulina, Acido Clorogenico e Fillanto Amaro, dette sostanze essendo ottenute da ed incluse nelle seguenti proporzioni da A a D: A) Cardo mariano e.s. frutti tit. 2,0% Silimarina (Silybum marianum gaertner) (25 mg) B) Tarassaco e.s. radice tit. 2,0% inulina (Taxrexacum officinale weber) (40 mg); C) Carciofo e.s. foglia tit. 2,5% acido clorogenico (Cynara scolymus L.) (40 mg); e D) Fillanto e.s. fiori e foglie tit. 15% tannini (Phyllantus ninni) (40 mg); dette sostanze essendo inoltre miscelate con i componenti seguenti: fruttosio; acido tartarico; sodio bicarbonato; L-taurina; acidificanti; acido citrico, acido malico; antiagglomerante: biossido di silicio; edulcorante: acesulfame potassico; aroma; vitamina PP; vitamina B6 cloridrato. CLAIMS 1. Composition for a natural food supplement to promote the physiological functionality of the liver, characterized by the fact of including in synergistic combination the substances: Silymarin, Inulin, Chlorogenic Acid and Bitter Fillanto, said substances being obtained from and included in the following proportions from A to D: A) Milk thistle d.e. fruit tit. 2.0% Silymarin (Silybum marianum gaertner) (25 mg) B) Dandelion dry extract root tit. 2.0% inulin (Taxrexacum officinale weber) (40 mg); C) Artichoke d.e. leaf tit. 2.5% chlorogenic acid (Cynara scolymus L.) (40 mg); And D) Fillanto e.s. flowers and leaves tit. 15% tannins (Phyllantus ninni) (40 mg); said substances being also mixed with the following components: fructose; tartaric acid; sodium bicarbonate; L-taurine; acidifiers; citric acid, malic acid; anti-caking agent: silicon dioxide; sweetener: acesulfame potassium; aroma; vitamin PP; vitamin B6 hydrochloride. 2. Composizione, secondo la rivendicazione 1 , caratterizzata dal fatto di comprendere i seguenti valori nutrizionali, riferiti ad una quantità di 100 g di composizione: - Vitamina PP: mg 180,0 - Vitamina B6: mg 20,0 - Fillanto: mg 800,0 Carciofo: mg 800,0 - Tarassaco: mg 800,0 - Cardomariano: mg 500,0 tali percentuali possono variare nell'intervallo ±30%. 2. Composition according to claim 1, characterized in that it comprises the following nutritional values, referred to a quantity of 100 g of composition: - Vitamin PP: 180.0 mg - Vitamin B6: 20.0 mg - Fillanto: 800.0 mg Artichoke: 800.0 mg - Dandelion: 800.0 mg - Cardomarian: 500.0 mg these percentages can vary in the range ± 30%. 3. Composizione, secondo la rivendicazione 1 , caratterizzata dal fatto di essere utilizzata per realizzare un integratore in polvere confezionato in bustine.3. Composition according to claim 1, characterized in that it is used to make a powder supplement packaged in sachets.
ITMI2009A000967A 2009-06-03 2009-06-03 COMPOSITION FOR A NATURAL FOOD SUPPLEMENT, PARTICULARLY TO ENCOURAGE THE PHYSIOLOGICAL FUNCTIONALITY OF THE LIVER. IT1394710B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ITMI2009A000967A IT1394710B1 (en) 2009-06-03 2009-06-03 COMPOSITION FOR A NATURAL FOOD SUPPLEMENT, PARTICULARLY TO ENCOURAGE THE PHYSIOLOGICAL FUNCTIONALITY OF THE LIVER.

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ITMI2009A000967A IT1394710B1 (en) 2009-06-03 2009-06-03 COMPOSITION FOR A NATURAL FOOD SUPPLEMENT, PARTICULARLY TO ENCOURAGE THE PHYSIOLOGICAL FUNCTIONALITY OF THE LIVER.

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IT1394710B1 IT1394710B1 (en) 2012-07-13

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001013930A1 (en) * 1999-08-26 2001-03-01 Jean Julia Dietetic use of cynara cardunculus and silybum marianum oils
US20030044512A1 (en) * 2001-08-31 2003-03-06 Watson Brenda F. Liver function improvement formulation
KR20040052930A (en) * 2004-05-18 2004-06-23 약초나라(주) Compounds for relief of alcoholic hangover and drug containing the compounds
US20050238654A1 (en) * 2004-04-26 2005-10-27 Yoshinori Takeda Compositions and methods for weight loss
US20070065456A1 (en) * 2005-09-20 2007-03-22 Woods Cindy J Nutritional supplements

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001013930A1 (en) * 1999-08-26 2001-03-01 Jean Julia Dietetic use of cynara cardunculus and silybum marianum oils
US20030044512A1 (en) * 2001-08-31 2003-03-06 Watson Brenda F. Liver function improvement formulation
US20050238654A1 (en) * 2004-04-26 2005-10-27 Yoshinori Takeda Compositions and methods for weight loss
KR20040052930A (en) * 2004-05-18 2004-06-23 약초나라(주) Compounds for relief of alcoholic hangover and drug containing the compounds
US20070065456A1 (en) * 2005-09-20 2007-03-22 Woods Cindy J Nutritional supplements

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "Ayrveda Neem Rasayana #5", 27 March 2008 (2008-03-27), pages 1 - 3, XP002563637, Retrieved from the Internet <URL:http://web.archive.org/web/20080327030050/http://www.ayurveda-herbs.com/5.htm> [retrieved on 20100116] *
BAGALKOTKAR, G.;SAGINEEDU, S.R.; SAAD, M.S.; STANSLAS, J.: "Phytochemicals from Phyllanthus niruri Linn and their pharmacological properties: a review", J PHARM PHARMACOL, vol. 58, no. 12, 2006, pages 1559 - 1570, XP008117324 *
CLIFFORD, M. N.: "Chlorogenic acids and other cinnamates - nature, occurrence and dietary burden.", JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, vol. 79, 1999, pages 362 - 372, XP002563618 *
SALLER, R.; BRIGNOLI, R.; MELZER, J.; MEIER, R.: "An updated systematic review with meta-analysis for the clinical evidence of silymarin.", FORSCH KOMPLEMENTMED., vol. 15, no. 1, 2008, pages 9 - 20, XP008117326 *

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