ITMI20011338A0 - Composizioni farmaceutiche orali a rilascio immediato del principio attivo - Google Patents

Composizioni farmaceutiche orali a rilascio immediato del principio attivo

Info

Publication number
ITMI20011338A0
ITMI20011338A0 IT2001MI001338A ITMI20011338A ITMI20011338A0 IT MI20011338 A0 ITMI20011338 A0 IT MI20011338A0 IT 2001MI001338 A IT2001MI001338 A IT 2001MI001338A IT MI20011338 A ITMI20011338 A IT MI20011338A IT MI20011338 A0 ITMI20011338 A0 IT MI20011338A0
Authority
IT
Italy
Prior art keywords
active ingredient
pharmaceutical compositions
immediate release
oral pharmaceutical
oral
Prior art date
Application number
IT2001MI001338A
Other languages
English (en)
Inventor
Maria Gabriella Massironi
Original Assignee
Farmatron Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmatron Ltd filed Critical Farmatron Ltd
Priority to IT2001MI001338A priority Critical patent/ITMI20011338A1/it
Publication of ITMI20011338A0 publication Critical patent/ITMI20011338A0/it
Priority to CA2451377A priority patent/CA2451377C/en
Priority to AU2002321081A priority patent/AU2002321081B2/en
Priority to PCT/EP2002/006748 priority patent/WO2003002101A1/en
Priority to AT02754706T priority patent/ATE303137T1/de
Priority to DK02754706T priority patent/DK1401405T3/da
Priority to US10/482,460 priority patent/US7867517B2/en
Priority to EP02754706A priority patent/EP1401405B1/en
Priority to ES02754706T priority patent/ES2247362T3/es
Priority to PT02754706T priority patent/PT1401405E/pt
Priority to JP2003508340A priority patent/JP4509552B2/ja
Priority to DE60205905T priority patent/DE60205905T2/de
Publication of ITMI20011338A1 publication Critical patent/ITMI20011338A1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
IT2001MI001338A 2001-06-26 2001-06-26 Composizioni farmaceutiche orali a rilascio immediato del principio attivo ITMI20011338A1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT2001MI001338A ITMI20011338A1 (it) 2001-06-26 2001-06-26 Composizioni farmaceutiche orali a rilascio immediato del principio attivo
DE60205905T DE60205905T2 (de) 2001-06-26 2002-06-19 Pharmazeutische zusammensetzung zur orale verabreichung mit verbesserter bioverfügbarkeit
AT02754706T ATE303137T1 (de) 2001-06-26 2002-06-19 Pharmazeutische zusammensetzung zur orale verabreichung mit verbesserter bioverfügbarkeit
AU2002321081A AU2002321081B2 (en) 2001-06-26 2002-06-19 Oral pharmaceutical compositions with improved biovailability
PCT/EP2002/006748 WO2003002101A1 (en) 2001-06-26 2002-06-19 Oral pharmaceutical compositions with improved bioavailability
CA2451377A CA2451377C (en) 2001-06-26 2002-06-19 Oral pharmaceutical compositions with improved bioavailability
DK02754706T DK1401405T3 (da) 2001-06-26 2002-06-19 Orale, farmaceutiske sammensætninger med forbedret biotilgængelighed
US10/482,460 US7867517B2 (en) 2001-06-26 2002-06-19 Oral pharmaceutical composition with improved bioavailability
EP02754706A EP1401405B1 (en) 2001-06-26 2002-06-19 Oral pharmaceutical compositions with improved bioavailability
ES02754706T ES2247362T3 (es) 2001-06-26 2002-06-19 Composiciones farmaceuticas orales con biodisponibilidad mejorada.
PT02754706T PT1401405E (pt) 2001-06-26 2002-06-19 Composicoes farmaceuticas orais com biodisponibilidade melhorada
JP2003508340A JP4509552B2 (ja) 2001-06-26 2002-06-19 向上されたバイオアベイラビリティを有する経口医薬組成物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001MI001338A ITMI20011338A1 (it) 2001-06-26 2001-06-26 Composizioni farmaceutiche orali a rilascio immediato del principio attivo

Publications (2)

Publication Number Publication Date
ITMI20011338A0 true ITMI20011338A0 (it) 2001-06-26
ITMI20011338A1 ITMI20011338A1 (it) 2002-12-26

Family

ID=11447931

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2001MI001338A ITMI20011338A1 (it) 2001-06-26 2001-06-26 Composizioni farmaceutiche orali a rilascio immediato del principio attivo

Country Status (12)

Country Link
US (1) US7867517B2 (it)
EP (1) EP1401405B1 (it)
JP (1) JP4509552B2 (it)
AT (1) ATE303137T1 (it)
AU (1) AU2002321081B2 (it)
CA (1) CA2451377C (it)
DE (1) DE60205905T2 (it)
DK (1) DK1401405T3 (it)
ES (1) ES2247362T3 (it)
IT (1) ITMI20011338A1 (it)
PT (1) PT1401405E (it)
WO (1) WO2003002101A1 (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US7612112B2 (en) 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
TWI312285B (en) 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
NZ538584A (en) * 2002-09-05 2007-05-31 Bharat Serums & Vaccines Ltd Stable liquid composition of oxazaphosphorine, mesna and etherified beta-cyclodextrin
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
EP1750717B1 (en) * 2004-02-11 2017-07-19 Rubicon Research Private Limited Controlled release pharmaceutical compositions with improved bioavailability
BRPI0517782A (pt) * 2004-11-17 2008-10-21 Ares Trading Sa formulações de benzotiazol e uso das mesmas
FR2891147B1 (fr) * 2005-09-28 2007-12-07 Ethypharm Sa Comprimes orodispersibles de principes actifs amers
US20090176882A1 (en) 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
CA2677649A1 (en) * 2007-02-09 2008-08-21 Forest Laboratories Holdings Limited Bioavailable formulations of heterocyclic compounds
CA2682661C (en) 2007-03-22 2017-03-14 Dendreon Corporation Methods for inducing a natural killer (nk) cell-mediated immune response and for increasing nk cell activity
FI20085369A0 (fi) * 2008-04-25 2008-04-25 Kuopion Yliopisto Gastroresistentti siklosporiiniformulaatio
EP3071182A1 (en) * 2013-11-18 2016-09-28 Sun Pharmaceutical Industries Ltd Oral dispersible composition of a dpp-iv inhibitor
CN106565861A (zh) * 2016-11-15 2017-04-19 常熟市凯力达蜂窝包装材料有限公司 改性环糊精的制备方法
WO2019060329A1 (en) * 2017-09-19 2019-03-28 The Regents Of The University Of Michigan CHARACTERIZATION AND APPLICATION OF POLYMERS FOR IN VITRO CHARACTERIZATION OF DRUG ABSORPTION WHICH IS RELEVANT IN VIVO

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8524421D0 (en) * 1985-10-03 1985-11-06 Boots Co Plc Therapeutic agents
GB8630273D0 (en) * 1986-12-18 1987-01-28 Til Medical Ltd Pharmaceutical delivery systems
ZA953078B (en) * 1994-04-28 1996-01-05 Alza Corp Effective therapy for epilepsies
FR2737121B1 (fr) * 1995-07-27 1997-10-03 Cl Pharma Nouvelles formulations galeniques du fenofibrate et leurs applications
JPH08283146A (ja) * 1995-10-23 1996-10-29 Boehringer Mannheim Gmbh 成形され、圧縮された徐放性単位投薬形態の調製法およびこうして得られた圧縮単位投薬形態
IT1276160B1 (it) * 1995-11-22 1997-10-27 Recordati Chem Pharm Composizioni farmaceutiche orali a pronto rilascio per sospensioni estemporanee
FR2742054B1 (fr) * 1995-12-06 1998-01-09 Synthelabo Compositions pharmaceutiques contenant un agent anti-inflammatoire et des ceramides vegetales
US5993858A (en) * 1996-06-14 1999-11-30 Port Systems L.L.C. Method and formulation for increasing the bioavailability of poorly water-soluble drugs
FR2756736B1 (fr) 1996-12-05 1999-03-05 Sanofi Sa Compositions pharmaceutiques contenant des derives de n-sulfonyl indoline
DK0996429T3 (da) * 1997-10-27 2003-05-26 Merck Patent Gmbh Faste opløsninger og faste dispersioner i vand tungtopløselige lægemidler
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
PT1318791E (pt) * 2000-09-22 2004-11-30 Galephar M F Composicao farmaceutica semi-solida de isotretinoina

Also Published As

Publication number Publication date
US7867517B2 (en) 2011-01-11
DE60205905T2 (de) 2006-02-16
US20040247666A1 (en) 2004-12-09
ES2247362T3 (es) 2006-03-01
ITMI20011338A1 (it) 2002-12-26
AU2002321081B2 (en) 2006-11-16
EP1401405A1 (en) 2004-03-31
JP4509552B2 (ja) 2010-07-21
DK1401405T3 (da) 2006-01-16
CA2451377A1 (en) 2003-01-09
EP1401405B1 (en) 2005-08-31
CA2451377C (en) 2011-08-09
ATE303137T1 (de) 2005-09-15
DE60205905D1 (de) 2005-10-06
PT1401405E (pt) 2005-11-30
JP2004534832A (ja) 2004-11-18
WO2003002101A1 (en) 2003-01-09

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