ITAN20120101A1 - COMPOSITION AS A TOPICAL USE, BASED ON GOAT COLOSTRO. - Google Patents
COMPOSITION AS A TOPICAL USE, BASED ON GOAT COLOSTRO. Download PDFInfo
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- ITAN20120101A1 ITAN20120101A1 IT000101A ITAN20120101A ITAN20120101A1 IT AN20120101 A1 ITAN20120101 A1 IT AN20120101A1 IT 000101 A IT000101 A IT 000101A IT AN20120101 A ITAN20120101 A IT AN20120101A IT AN20120101 A1 ITAN20120101 A1 IT AN20120101A1
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- 230000000699 topical effect Effects 0.000 title claims description 9
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- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 3
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- 235000008397 ginger Nutrition 0.000 claims description 3
- 235000002532 grape seed extract Nutrition 0.000 claims description 3
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- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 description 2
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- 230000000844 anti-bacterial effect Effects 0.000 description 2
- KZNIFHPLKGYRTM-UHFFFAOYSA-N apigenin Chemical compound C1=CC(O)=CC=C1C1=CC(=O)C2=C(O)C=C(O)C=C2O1 KZNIFHPLKGYRTM-UHFFFAOYSA-N 0.000 description 2
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- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Description
DESCRIZIONE DESCRIPTION
a corredo di una domanda di brevetto per invenzione industriale avente per titolo: accompanying a patent application for an industrial invention entitled:
"COMPOSIZIONE A USO TOPICO, A BASE DI COLOSTRO DI CAPRA" "COMPOSITION FOR TOPICAL USE, BASED ON GOAT COLOSTRUM"
TESTO DELLA DESCRIZIONE TEXT OF THE DESCRIPTION
La presente domanda di brevetto per invenzione industriale ha per oggetto una composizione a uso topico a base di colostro di capra, in particolare come disinfettante, reidratante e antiossidante. The present patent application for industrial invention relates to a composition for topical use based on goat colostrum, in particular as a disinfectant, rehydrator and antioxidant.
Sono noti in commercio integratori in capsule o spray a base di colostro bovino o caprino. Supplements in capsules or sprays based on bovine or goat colostrum are known on the market.
Inoltre esistono in commercio estratti di mirtillo rosso, proponibili come estratti in granulato, tintura madre, maceratoglicerico, estratto secco o creme o spray per uso locale, che sono utilizzati come coadiuvanti per il microcircolo del sangue e per l'apparato vascolare. In addition, there are extracts of cranberry on the market, which can be proposed as granulated extracts, mother tincture, maceratoglycerine, dry extract or creams or sprays for local use, which are used as adjuvants for the microcirculation of the blood and for the vascular system.
Sono altresì noti in commercio prodotti fitoterapici a base di Matricaria Romana, che offrono benefici grazie alla titolazione in apigenina o in bisabololo e camazolene in estratto secco, MG, tintura madre, capolini utilizzabili in decotto tisana. Phytotherapeutic products based on Matricaria Romana are also known on the market, which offer benefits thanks to the titration in apigenin or bisabolol and chamazolene in dry extract, MG, mother tincture, flower heads that can be used in herbal tea decoction.
Scopo della presente invenzione à ̈ di fornire una composizione a uso topico sia più efficiente e versatile, come disinfettante, reidratante e antiossidante, rispetto alle composizioni topiche esistenti in commercio. The purpose of the present invention is to provide a composition for topical use that is more efficient and versatile, as a disinfectant, rehydrator and antioxidant, than the topical compositions available on the market.
Questo scopo à ̈ raggiunto in accordo all’invenzione, con le caratteristiche elencate nell’annessa rivendicazione indipendente 1. This object is achieved in accordance with the invention, with the characteristics listed in the attached independent claim 1.
Realizzazioni vantaggiose appaiono dalle rivendicazioni dipendenti. Advantageous embodiments appear from the dependent claims.
La composizione topica secondo l’invenzione comprende: colostro di capra (A), matricaria (B) e mirtillo rosso (C). The topical composition according to the invention includes: goat colostrum (A), matricaria (B) and cranberry (C).
Preferibilmente il colostro di capra (A) à ̈ liofilizzato e la matricaria (B) e il mirtillo rosso (C) sono in estratto secco. Il colostro caprino à ̈ liofilizzato per mantenere le sue proprietà organolettiche, l'estratto secco di matricaria (B) e mirtillo rosso (C) à ̈ consigliabile per non alterare termogenicamente il colostro liofilizzato ed implementarne le proprietà . Goat colostrum (A) is preferably freeze-dried and matricaria (B) and cranberry (C) are in dry extract. Goat colostrum is freeze-dried to maintain its organoleptic properties, the dry extract of matricaria (B) and cranberry (C) is recommended in order not to thermogenically alter the freeze-dried colostrum and to implement its properties.
Vantaggiosamente il rapporto ponderale della matricaria (B) e del mirtillo rosso (C) rispetto al colostro di capra (A) Ã ̈ il seguente: Advantageously, the weight ratio of matricaria (B) and cranberry (C) with respect to goat colostrum (A) is the following:
B = 25-35% A B = 25-35% A
C = 20 – 20% A C = 20 - 20% A
La composizione secondo l’invenzione può essere Crema, Gel, Cerotto o Spray. The composition according to the invention can be Cream, Gel, Patch or Spray.
La matricaia (B) comprende le seguenti sostanze: The matrix (B) includes the following substances:
• Apigenina avente attività antinfiammatoria e spasmolitica, antiossidante e antistaminica; â € ¢ Apigenin with anti-inflammatory and spasmolytic, antioxidant and antihistamine activity;
• Camazulene avente attività antibatterica; e â € ¢ Camazulene having antibacterial activity; And
• Bisabololo avente attività antinfiammatoria. â € ¢ Bisabolol with anti-inflammatory activity.
La combinazione colostro di capra (A), matricaria (B) e mirtillo rosso (C) crea un effetto sinergico per l’assorbimento del colostro di capra da parte delle cellule dell’organismo umano.. The combination of goat colostrum (A), matricaria (B) and cranberry (C) creates a synergistic effect for the absorption of goat colostrum by the cells of the human organism.
Sorprendentemente tutto l'agglomerato liofilizzato del colostro caprino, viene assorbito completamente dall'organismo, senza disperderne alcun microgrammo, poiché al livello del mesenchima sia i fitoattivi della matricaria romana che quelli del mirtillo rosso supportano e favoriscono con un'azione preliminare e sinergica tale compito, garantendone infine un'azione cellulare superlativa, anche nel suo assorbimento. L'azione diretta dei fitocomposti di matricaria e mirtillo rosso apre la via di assorbimento al colostro, che sostiene un'azione di supporto al sistema immunitario nel suo complesso. Surprisingly, all the lyophilized agglomerate of goat colostrum is completely absorbed by the body, without wasting any micrograms, since at the level of the mesenchyme both the phytoactives of Roman matricaria and those of cranberry support and favor this with a preliminary and synergistic action. task, finally guaranteeing a superlative cellular action, even in its absorption. The direct action of the phytocompounds of matricaria and cranberry opens the path of absorption to the colostrum, which supports an action to support the immune system as a whole.
Tale composizione per uso topico offre un'attività disinfettante, reidratante con potente azione antiossidante, con effetto anti-ageing sugli stati infiammatori della cute, come ulcerazioni, ferite di vario tipo, piaghe, peeling, atopie, macchie pigmentarie e ragadi. This composition for topical use offers a disinfectant, rehydrating activity with a powerful antioxidant action, with an anti-aging effect on inflammatory conditions of the skin, such as ulcerations, wounds of various types, sores, peeling, atopias, pigment spots and fissures.
Vantaggiosamente alla composizione per uso topico possono essere aggiunte una o più delle seguenti sostanze: Calendula Officinalis, Resvetrarolo da semi d'uva, Acido ialuronico, Picnogenolo. Advantageously, one or more of the following substances can be added to the composition for topical use: Calendula Officinalis, Resvetrarolo from grape seeds, Hyaluronic acid, Pycnogenol.
La Calendula Officinalis ha un’azione cicatrizzante e batteriostatica arricchisce le proprietà già esplicate nelle sostanze (A, B C) summenzionate. Calendula Officinalis has a healing and bacteriostatic action enriches the properties already explained in the substances (A, B C) mentioned above.
Il Resvetrarolo da semi d'uva ha un’azione rivitalizzante del microcircolo e vasoprotettrice, sostiene ulteriormente l'apparato strutturale del derma. Resvetrarolo from grape seeds has a revitalizing action on the microcirculation and vasoprotective, further supports the structural apparatus of the dermis.
L’Acido Ialuronico implementa l'attività del collagene, garantendo un suo sostegno importante nell'apparato selettivo del collagene. Hyaluronic Acid implements the activity of collagen, ensuring its important support in the selective collagen system.
Il Picnogenolo à ̈ un estratto da corteccia di pino marittimo che esplica un'importante attività antinfiammatoria, dimostrando un'eccellente penetrazione cutanea dopo meno di un ora dall'assunzione, mantenendo le sue attività sull'organismo per diverse ore. Il Picnogenolo si lega in modo selettivo a collagene ed elastina proteggendole dalla degradazione enzimatica, favorisce la vasodilatazione, rilassando la muscolatura liscia, prevenendo l'aggregazione delle piastrine, accelera anche i tempi di guarigione delle ferite della cute, diminuendo la formazione di tessuto cicatriziale; Pertanto il Picnogenolo costituisce con A B C un elemento fondamentale, solo se ad essi associato, per la riparazione e rigenerazione della cute. Pycnogenol is an extract from maritime pine bark that performs an important anti-inflammatory activity, demonstrating excellent skin penetration less than an hour after taking it, maintaining its activities on the body for several hours. Pycnogenol binds selectively to collagen and elastin protecting them from enzymatic degradation, promotes vasodilation, relaxing smooth muscle, preventing platelet aggregation, also accelerates the healing time of skin wounds, decreasing the formation of scar tissue; Therefore Pycnogenol constitutes with A B C a fundamental element, only if associated with them, for the repair and regeneration of the skin.
La composizione di base comprende solo colostro di capra (A), matricaria (B) e mirtillo rosso (C). La composizione di base vantaggiosamente può essere arricchita con opportune sostanze per migliorane gli effetti. In seguito sono descritti diversi utilizzi della composizione di base secondo l’invenzione e soluzioni vantaggiose della composizione di base arricchito. The basic composition includes only goat colostrum (A), matricaria (B) and cranberry (C). The basic composition can advantageously be enriched with suitable substances to improve its effects. Hereinafter various uses of the basic composition according to the invention and advantageous solutions of the enriched basic composition are described.
1) Trattamento di patologie infiammatorie e dolorose La composizione di base si à ̈ dimostrato un coadiuvante per il trattamento di infiammazioni di origine muscolare e per alleviare il dolore provocato da tali infiammazioni. 1) Treatment of inflammatory and painful pathologies The basic composition has proved to be an adjuvant for the treatment of inflammations of muscular origin and to relieve the pain caused by such inflammations.
Vantaggiosamente, per migliorare l’efficienza del trattamento delle patologie infiammatorie e dolorose, alla composizione di base possono essere aggiunte una o più delle seguenti sostanze, in percentuale peso rispetto al colostro di capra (A): Advantageously, to improve the efficiency of the treatment of inflammatory and painful pathologies, one or more of the following substances can be added to the basic composition, in percentage by weight with respect to goat colostrum (A):
equisetum arvensis estratto secco 20 %, harpagophytum estratto secco 10 %, equisetum arvensis dry extract 20%, harpagophytum dry extract 10%,
vitis vinifera estratto secco 5 %, vitis vinifera dry extract 5%,
boswelia serrata estratto secco 5 %, boswelia serrata dry extract 5%,
zenzero estratto secco 5 %, ginger dry extract 5%,
magnesio pidolinato 5 %. magnesium pidolinate 5%.
L’Equisetum Arvensis esplica un'attività mineralizzante del tessuto osseo, atta a coadiuvare un'azione di sostegno dell'apparato scheletrico. Equisetum Arvensis performs a mineralizing activity of the bone tissue, capable of assisting a supporting action of the skeletal system.
L'Harpagophytum offre un'attività antiflogistica, antinfiammatoria, antigottosa e antireumatica in modo da aumentare l’attività antiinfiammatoria della composizione di base. Harpagophytum offers anti-inflammatory, anti-inflammatory, anti-gout and anti-rheumatic activity in order to increase the anti-inflammatory activity of the basic composition.
La Vitis Vinifera à ̈ ricca di flavonoidi, migliora la qualità del microcircolo esprimendo contestualmente un miglioramento negli edemi ed ematomi presenti nelle aree contuse, pertanto va ulteriormente a sostenere eventi traumatici di qualsiasi tipo. Vitis Vinifera is rich in flavonoids, it improves the quality of the microcirculation by expressing at the same time an improvement in the edema and hematomas present in the bruised areas, therefore it further supports traumatic events of any kind.
La Boswelia Serrata à ̈ un antinfiammatorio che crea un effetto sinergico con le qualità antinfiammatorie delle altre sostanze della composizione. Boswelia Serrata is an anti-inflammatory that creates a synergistic effect with the anti-inflammatory qualities of the other substances in the composition.
Lo Zenzero contiene zingiberina che genera un’azione rigeneratrice del drenaggio epatico, garantendo una risposta ottimale a tutto il circuito metabolico, favorendo la liberazione di radicali liberi; causa spesso di impregnazione e conseguente algie di focus nei distretti muscolari; à ̈ pertanto importante la sua presenza perché coadiuva e sinergizza in maniera esemplare i precedenti fitoattivi citati. Ginger contains zingiberin which generates a regenerating action of the hepatic drainage, guaranteeing an optimal response to the entire metabolic circuit, favoring the release of free radicals; it often causes impregnation and consequent focus pain in the muscle areas; Its presence is therefore important because it assists and synergizes in an exemplary way the previous phytoactives mentioned.
2) Trattamento delle patologie dentali 2) Treatment of dental pathologies
Esperimenti clinici hanno mostrato che pazienti che hanno utilizzato la composizione di base secondo l’invenzione, mediante spruzzi nel cavo orale, hanno migliorato la riparazione del tessuto per l'impiantistica dentale, coadiuvando pertanto la cicatrizzazione delle mucose dentali, rispetto a pazienti che non hanno utilizzato tale composizione. Clinical experiments have shown that patients who used the basic composition according to the invention, by means of sprays in the oral cavity, have improved the repair of the tissue for dental implants, thus assisting the healing of the dental mucosa, compared to patients who do not they used this composition.
Vantaggiosamente, per migliore le prestazioni nel trattamento di patologie dentali, la composizione secondo l’invenzione può comprendere inoltre uno o più delle seguenti sostanze: Calendula Officinalis, Timo, Arnica. Advantageously, for better performance in the treatment of dental pathologies, the composition according to the invention can also comprise one or more of the following substances: Calendula Officinalis, Thyme, Arnica.
La Calendula Officinalis ha azione antinfiammatoria, antibatterica e cicatrizzante, quindi consente in tempi più rapidi la cicatrizzazione delle mucose dentali. Calendula Officinalis has an anti-inflammatory, antibacterial and healing action, therefore it allows the healing of the dental mucous membranes in a faster time.
Il Timo à ̈ un disinfettante e antisettico del cavo orale e garantisce un'ulteriore qualità per le mucose della bocca. L’effetto sinergico del Timo con gli altri ingredienti della composizione implementa le proprietà di far regredire le flogosi della mucosa orale in tempi più brevi. Thyme is a disinfectant and antiseptic of the oral cavity and guarantees an additional quality for the mucous membranes of the mouth. The synergistic effect of Thyme with the other ingredients of the composition implements the properties of regressing the inflammation of the oral mucosa in a shorter time.
L'Arnica in maniera stereotopica viene definita a livello internazionale la pianta che “risolve il trauma†. Pertanto l’arnica assieme agli altri componenti contribuisce al trattamento delle patologie dell’apparato dentale e velocizza gli effetti curativi degli altri ingredienti della composizione secondo l’invenzione. Arnica is stereotopically defined internationally as the plant that â € œresolves traumaâ €. Therefore, Arnica together with the other components contributes to the treatment of the pathologies of the dental apparatus and speeds up the healing effects of the other ingredients of the composition according to the invention.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000101A ITAN20120101A1 (en) | 2012-08-06 | 2012-08-06 | COMPOSITION AS A TOPICAL USE, BASED ON GOAT COLOSTRO. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000101A ITAN20120101A1 (en) | 2012-08-06 | 2012-08-06 | COMPOSITION AS A TOPICAL USE, BASED ON GOAT COLOSTRO. |
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| ITAN20120101A1 true ITAN20120101A1 (en) | 2014-02-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000101A ITAN20120101A1 (en) | 2012-08-06 | 2012-08-06 | COMPOSITION AS A TOPICAL USE, BASED ON GOAT COLOSTRO. |
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| IT (1) | ITAN20120101A1 (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6258383B1 (en) * | 1998-08-14 | 2001-07-10 | Lactoferrin Products Company | Dietary supplement combining colostrum and lactoferrin in a mucosal delivery format |
| WO2008122286A1 (en) * | 2007-04-04 | 2008-10-16 | Gumlink A/S | Center-filled chewing gum product for dental care |
| WO2012116445A1 (en) * | 2011-02-28 | 2012-09-07 | Technologies Khlôros Inc. | Chewable vehicle for mouth absorption |
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2012
- 2012-08-06 IT IT000101A patent/ITAN20120101A1/en unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6258383B1 (en) * | 1998-08-14 | 2001-07-10 | Lactoferrin Products Company | Dietary supplement combining colostrum and lactoferrin in a mucosal delivery format |
| WO2008122286A1 (en) * | 2007-04-04 | 2008-10-16 | Gumlink A/S | Center-filled chewing gum product for dental care |
| WO2012116445A1 (en) * | 2011-02-28 | 2012-09-07 | Technologies Khlôros Inc. | Chewable vehicle for mouth absorption |
Non-Patent Citations (1)
| Title |
|---|
| FERNANDEZ A ET AL: "Influence of colostrum treated by heat on immunity function in goat kids", COMPARATIVE IMMUNOLOGY, MICROBIOLOGY AND INFECTIOUS DISEASES, PERGAMON PRESS, OXFORD, GB, vol. 29, no. 5-6, 15 September 2006 (2006-09-15), pages 353 - 364, XP027906487, ISSN: 0147-9571, [retrieved on 20060901] * |
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