IT8821719A0 - PIPERIDINE PONTATE, THEIR PREPARATION AND THEIR USE AS MEDICINES. - Google Patents

PIPERIDINE PONTATE, THEIR PREPARATION AND THEIR USE AS MEDICINES.

Info

Publication number
IT8821719A0
IT8821719A0 IT8821719A IT2171988A IT8821719A0 IT 8821719 A0 IT8821719 A0 IT 8821719A0 IT 8821719 A IT8821719 A IT 8821719A IT 2171988 A IT2171988 A IT 2171988A IT 8821719 A0 IT8821719 A0 IT 8821719A0
Authority
IT
Italy
Prior art keywords
pontate
piperidine
medicines
preparation
piperidine pontate
Prior art date
Application number
IT8821719A
Other languages
Italian (it)
Other versions
IT1226742B (en
Inventor
Laszlo Revesz
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT8821719A0 publication Critical patent/IT8821719A0/en
Application granted granted Critical
Publication of IT1226742B publication Critical patent/IT1226742B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT8821719A 1987-08-20 1988-08-19 BRIDGE PIPERIDINS, THEIR PREPARATION AND THEIR USE AS MEDICATIONS. IT1226742B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3727733 1987-08-20

Publications (2)

Publication Number Publication Date
IT8821719A0 true IT8821719A0 (en) 1988-08-19
IT1226742B IT1226742B (en) 1991-02-05

Family

ID=6334102

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8821719A IT1226742B (en) 1987-08-20 1988-08-19 BRIDGE PIPERIDINS, THEIR PREPARATION AND THEIR USE AS MEDICATIONS.

Country Status (17)

Country Link
JP (1) JPS6471874A (en)
KR (1) KR950000509B1 (en)
AU (1) AU2110588A (en)
DE (1) DE3827253A1 (en)
DK (1) DK465188A (en)
FI (1) FI883838A (en)
FR (1) FR2619565A1 (en)
GB (1) GB2208862A (en)
GR (1) GR880100538A (en)
IL (1) IL87489A0 (en)
IT (1) IT1226742B (en)
LU (1) LU87314A1 (en)
NL (1) NL8802059A (en)
PL (1) PL274318A1 (en)
PT (1) PT88296B (en)
SE (1) SE8802926L (en)
ZA (1) ZA886180B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69004924T2 (en) 1989-04-21 1994-05-19 Sandoz Ag THERAPEUTIC USE OF 5-HT3 RECEPTOR ANTAGONISTS.
GB2236751B (en) * 1989-10-14 1993-04-28 Wyeth John & Brother Ltd Heterocyclic compounds
US5225419A (en) * 1989-10-14 1993-07-06 John Wyeth & Brother, Limited Certain 1,8-ethano or propano-1,4-dihydro-4-oxo-quinoline-3-carboxamides and derivatives thereof
US5187166A (en) * 1990-07-31 1993-02-16 Nisshin Flour Milling Co., Ltd. Azabicyclo derivatives and their use as antiemetics
US5225412A (en) * 1991-04-29 1993-07-06 Hoechst-Roussel Pharmaceuticals Incorporated Benzoisothiazole-and benzisoxazole-3-carboxamides
US5143923B1 (en) * 1991-04-29 1993-11-02 Hoechst-Roussel Pharmaceuticals Incorporated Benzoisothiazole-and benzisoxazole-3-carboxamides
DE4126999A1 (en) * 1991-08-16 1993-02-18 Basf Ag HERBICIDE AGENT, CONTAINING 3-AMINOBENZO (B) THIOPHENE AS ANTIDOTS
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
DE10164139A1 (en) 2001-12-27 2003-07-10 Bayer Ag 2-heteroaryl carboxamides
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
NZ587551A (en) 2004-06-24 2012-01-12 Vertex Pharma 5-Amino-phenol derivatives such as 5-amino-2,4-di-tert-butyl-phenol
US7592461B2 (en) 2005-12-21 2009-09-22 Bristol-Myers Squibb Company Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
SI3219705T1 (en) 2005-12-28 2020-08-31 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions of the amorphous form of n-(2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl)-1,4-dihydro-4-oxoquinoline-3-carboxamide
EP2046753A2 (en) 2006-07-06 2009-04-15 Brystol-Myers Squibb Company Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type i inhibitors
AU2008210455A1 (en) 2007-01-31 2008-08-07 Vertex Pharmaceuticals Incorporated 2-aminopyridine derivatives useful as kinase inhibitors
CA2731451A1 (en) 2008-07-23 2010-01-28 Vertex Pharmaceuticals Incorporated Pyrazolopyridine kinase inhibitors
MX2011000837A (en) 2008-07-23 2011-04-05 Vertex Pharma Tri-cyclic pyrazolopyridine kinase inhibitors.
US8569337B2 (en) 2008-07-23 2013-10-29 Vertex Pharmaceuticals Incorporated Tri-cyclic pyrazolopyridine kinase inhibitors
AU2009279611A1 (en) 2008-08-06 2010-02-11 Vertex Pharmaceuticals Incorporated Aminopyridine kinase inhibitors
ES2396300T3 (en) 2008-11-19 2013-02-20 Envivo Pharmaceuticals, Inc. Treatment of cognitive disorders with (R) -7-chloro-N- (quinuclidin-3-yl) benzo [b] thiophene-2-carboxamide and pharmaceutically acceptable salts thereof
RU2543714C2 (en) 2009-03-20 2015-03-10 Вертекс Фармасьютикалз Инкорпорейтед Method of obtaining modulators of cystic fibrousis transmembrane conductance regulator
WO2010129668A1 (en) 2009-05-06 2010-11-11 Vertex Pharmaceuticals Incorporated Pyrazolopyridines
MX2012008643A (en) 2010-01-27 2013-02-26 Vertex Pharma Pyrazolopyrimidine kinase inhibitors.
CN102869663A (en) 2010-01-27 2013-01-09 沃泰克斯药物股份有限公司 Pyrazolopyrazine kinase inhibitors
JP5769733B2 (en) 2010-01-27 2015-08-26 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ Pyrazolopyridine kinase inhibitor
WO2011146511A1 (en) 2010-05-17 2011-11-24 Envivo Pharmaceuticals, Inc. A crystalline form of (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride monohydrate
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
BR112014021090B1 (en) 2012-02-27 2023-01-24 Vertex Pharmaceuticals Incorporated PHARMACEUTICAL COMPOSITION AND USE OF N-[2,4-BIS(1,1-DIMETHYLethyl)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE3-CARBOXAMIDE IN THE PREPARATION OF THE SAME
AU2013259871A1 (en) 2012-05-08 2014-11-20 Forum Pharmaceuticals Inc. Methods of maintaining, treating or improving cognitive function
RU2749213C2 (en) 2014-10-07 2021-06-07 Вертекс Фармасьютикалз Инкорпорейтед Co-crystals of transmembrane conduction regulator modulators in cystic fibrosis
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy
JP2022552019A (en) 2019-10-18 2022-12-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 3-Phenylsulfonyl-quinoline derivatives as agents for the treatment of pathological vascular disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0095262B1 (en) * 1982-05-11 1986-12-03 Beecham Group Plc Azabicycloalkane derivatives, their preparation and medicaments containing them
FR2531083B1 (en) * 1982-06-29 1986-11-28 Sandoz Sa NOVEL PIPERIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES
CH664567A5 (en) * 1983-08-26 1988-03-15 Sandoz Ag AROMATIC CARBONIC ACID AND SULPHONIC ACID ESTERS OR AMIDES.

Also Published As

Publication number Publication date
KR950000509B1 (en) 1995-01-24
SE8802926D0 (en) 1988-08-18
PT88296A (en) 1989-06-30
DK465188D0 (en) 1988-08-18
IT1226742B (en) 1991-02-05
SE8802926L (en) 1989-02-21
GB2208862A (en) 1989-04-19
FI883838A0 (en) 1988-08-18
JPS6471874A (en) 1989-03-16
GB8819438D0 (en) 1988-09-21
GR880100538A (en) 1989-05-25
IL87489A0 (en) 1989-01-31
DE3827253A1 (en) 1989-03-02
FI883838A (en) 1989-02-21
PT88296B (en) 1995-03-31
NL8802059A (en) 1989-03-16
PL274318A1 (en) 1989-04-17
KR890003679A (en) 1989-04-17
AU2110588A (en) 1989-03-23
ZA886180B (en) 1990-07-25
LU87314A1 (en) 1989-03-08
FR2619565A1 (en) 1989-02-24
DK465188A (en) 1989-02-21

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