IT8449028A1 - Complessi di platino - diammina dotati di attivita' antitumorale e bassa tossicita' renale - Google Patents
Complessi di platino - diammina dotati di attivita' antitumorale e bassa tossicita' renaleInfo
- Publication number
- IT8449028A1 IT8449028A1 IT1984A49028A IT4902884A IT8449028A1 IT 8449028 A1 IT8449028 A1 IT 8449028A1 IT 1984A49028 A IT1984A49028 A IT 1984A49028A IT 4902884 A IT4902884 A IT 4902884A IT 8449028 A1 IT8449028 A1 IT 8449028A1
- Authority
- IT
- Italy
- Prior art keywords
- platinum
- tumor activity
- kidney toxicity
- diamine complexes
- low kidney
- Prior art date
Links
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 title 2
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 231100000417 nephrotoxicity Toxicity 0.000 title 1
- 229910052697 platinum Inorganic materials 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP58194358A JPS6087295A (ja) | 1983-10-19 | 1983-10-19 | 新規白金錯体 |
Publications (3)
Publication Number | Publication Date |
---|---|
IT8449028A0 IT8449028A0 (it) | 1984-10-18 |
IT8449028A1 true IT8449028A1 (it) | 1986-05-05 |
IT1178151B IT1178151B (it) | 1987-09-09 |
Family
ID=16323246
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT49028/84A IT1178151B (it) | 1983-10-19 | 1984-11-05 | Complessi di platino-diammina dotati di attivita' antitumorale e bassa tossicita' renale |
Country Status (13)
Country | Link |
---|---|
US (1) | US4607114A (it) |
JP (1) | JPS6087295A (it) |
KR (1) | KR850003408A (it) |
BE (1) | BE900842A (it) |
DE (1) | DE3438440A1 (it) |
DK (1) | DK499584A (it) |
ES (1) | ES8604985A1 (it) |
FR (1) | FR2553777B1 (it) |
GB (1) | GB2148891B (it) |
HU (1) | HUT37627A (it) |
IT (1) | IT1178151B (it) |
NL (1) | NL8403087A (it) |
SE (1) | SE8405188L (it) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4952676A (en) * | 1984-06-27 | 1990-08-28 | Johnson Matthey Plc | Monoclonal antibody-platinum co-ordination compound complex |
ATE63919T1 (de) * | 1984-06-27 | 1991-06-15 | Johnson Matthey Plc | Platinkoordinationsverbindungen. |
EP0169645A1 (en) * | 1984-06-27 | 1986-01-29 | Johnson Matthey Public Limited Company | Platinum co-ordination compounds |
HU193809B (en) * | 1984-09-12 | 1987-12-28 | Chugai Pharmaceutical Co Ltd | Process for producing new platinum complexes |
US4737589A (en) * | 1985-08-27 | 1988-04-12 | Nippon Kayaku Kabushiki Kaisha | Platinum Complexes |
ES8606204A1 (es) * | 1985-09-05 | 1986-04-01 | Ferrer Int | Procedimiento de obtencion de nuevos complejos de platino (ii) derivados del 1,1-ciclobutanodicarboxilato |
JPS6259289A (ja) * | 1985-09-07 | 1987-03-14 | Yoshinori Kitani | 新規な白金(2)錯体 |
JPS62207283A (ja) * | 1986-03-07 | 1987-09-11 | Yoshinori Kitani | 新規な白金錯体 |
JPS63203692A (ja) * | 1987-02-19 | 1988-08-23 | Nippon Kayaku Co Ltd | 新規白金錯体 |
JPS63303988A (ja) * | 1987-06-02 | 1988-12-12 | Toray Ind Inc | 新規白金(2)錯体および悪性腫瘍治療剤 |
US5072011A (en) * | 1988-02-02 | 1991-12-10 | Johnson Matthey, Inc. | Pt(IV) complexes |
ES2063119T3 (es) * | 1988-02-02 | 1995-01-01 | Johnson Matthey Inc | Complejos de pt (iv). |
FR2644458B1 (fr) * | 1989-03-17 | 1991-07-05 | Bellon Labor Sa Roger | Nouveaux complexes derives du platine, leur preparation et les compositions pharmaceutiques qui les contiennent |
US5196555A (en) * | 1989-10-17 | 1993-03-23 | Bristol-Myers Squibb Company | Water and solvent soluble axial hydroxy and mono- and di- carboxylic acid derivatives having high tumor activity |
FR2691151A1 (fr) * | 1992-05-14 | 1993-11-19 | Bellon Labor Sa Roger | Nouveaux dérivés du platine (IV), leur préparation et les compositions pharmaceutiques qui les contiennent. |
EP1019420B1 (en) * | 1995-05-09 | 2003-08-06 | Kreatech Biotechnology B.V. | Methods for the production of platinum-based linkers between labels and bio-organic molecules, for labelling bio-organic molecules, for detecting biological substances of interest |
US6338943B1 (en) | 1996-10-08 | 2002-01-15 | Kreatech Biotechnology B.V. | Methods for labeling nucleotides, labeled nucleotides and useful intermediates |
AUPQ641100A0 (en) * | 2000-03-23 | 2000-04-15 | Australia Nuclear Science & Technology Organisation | Methods of synthesis and use of radiolabelled platinum chemotherapeutic ag ents |
DE10141528B4 (de) * | 2001-08-24 | 2006-08-10 | Faustus Forschungs Cie. Translational Cancer Research Gmbh | Platin(II)- und Platin(IV)-Komplexe und ihre Verwendung |
KR100663887B1 (ko) * | 2004-05-18 | 2007-01-03 | 광주과학기술원 | 수용성 초고분자 백금 착화합물 및 그 제조방법 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6034958B2 (ja) * | 1978-09-02 | 1985-08-12 | 喜徳 喜谷 | 新規白金錯体 |
NL181434C (nl) * | 1980-01-03 | 1987-08-17 | Tno | Platina(iv)-diamine-complexen, alsmede hun bereiding en toepassing. |
JPS5716895A (en) * | 1980-07-05 | 1982-01-28 | Otsuka Chem Co Ltd | Platinum 2 complex and antitumor agent containing the same as active principle |
NL8101026A (nl) * | 1981-03-03 | 1982-10-01 | Tno | Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel. |
JPS6034983A (ja) * | 1983-08-05 | 1985-02-22 | Yoshinori Kitani | 新規な白金錯体 |
-
1983
- 1983-10-19 JP JP58194358A patent/JPS6087295A/ja active Granted
-
1984
- 1984-10-10 NL NL8403087A patent/NL8403087A/nl not_active Application Discontinuation
- 1984-10-12 KR KR1019840006312A patent/KR850003408A/ko not_active Application Discontinuation
- 1984-10-16 FR FR8415848A patent/FR2553777B1/fr not_active Expired
- 1984-10-16 US US06/661,433 patent/US4607114A/en not_active Expired - Fee Related
- 1984-10-17 SE SE8405188A patent/SE8405188L/ not_active Application Discontinuation
- 1984-10-18 ES ES536865A patent/ES8604985A1/es not_active Expired
- 1984-10-18 HU HU843905A patent/HUT37627A/hu unknown
- 1984-10-18 DK DK499584A patent/DK499584A/da not_active Application Discontinuation
- 1984-10-18 BE BE0/213848A patent/BE900842A/fr not_active IP Right Cessation
- 1984-10-19 GB GB08426539A patent/GB2148891B/en not_active Expired
- 1984-10-19 DE DE19843438440 patent/DE3438440A1/de not_active Ceased
- 1984-11-05 IT IT49028/84A patent/IT1178151B/it active
Also Published As
Publication number | Publication date |
---|---|
DE3438440A1 (de) | 1985-05-02 |
GB2148891A (en) | 1985-06-05 |
DK499584D0 (da) | 1984-10-18 |
ES536865A0 (es) | 1986-02-16 |
BE900842A (fr) | 1985-04-18 |
ES8604985A1 (es) | 1986-02-16 |
FR2553777B1 (fr) | 1988-02-19 |
GB8426539D0 (en) | 1984-11-28 |
SE8405188L (sv) | 1985-04-20 |
HUT37627A (en) | 1986-01-23 |
JPS6087295A (ja) | 1985-05-16 |
NL8403087A (nl) | 1985-05-17 |
SE8405188D0 (sv) | 1984-10-17 |
FR2553777A1 (fr) | 1985-04-26 |
GB2148891B (en) | 1987-01-14 |
US4607114A (en) | 1986-08-19 |
IT1178151B (it) | 1987-09-09 |
KR850003408A (ko) | 1985-06-17 |
JPH0412277B2 (it) | 1992-03-04 |
DK499584A (da) | 1985-04-20 |
IT8449028A0 (it) | 1984-10-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IT8449028A1 (it) | Complessi di platino - diammina dotati di attivita' antitumorale e bassa tossicita' renale | |
IT1178947B (it) | Preparazioni farmaceutiche aventi ridotta tossicita | |
DK60691A (da) | Cyclodextrin-peptidkomplekser | |
DK459185A (da) | Lukket blodposesystem | |
DE3472881D1 (de) | N-phenylsulfonyl-n'-pyrimidinyl- and -triazinyl urea | |
BR8401023A (pt) | Trator de cabine inclinavel | |
FI865260A0 (fi) | Eetteri-isonitriilejä ja niiden radiomerkattuja komplekseja | |
FR2600103B1 (fr) | Structure d'habitation multi-familiale | |
IT1178243B (it) | Composti 5-eteroarilimidazol-2-onici dotati di attivita' cardiotonica | |
IT8323422A0 (it) | Glicosaminoglicani modificati dotati di attivita' antitrombotica. | |
FI932114A0 (fi) | Maolspecifika erytrocyter och tromboerytrocyter | |
NO932212D0 (no) | Polyaminmedikament-harpikskomplekser | |
DE3888541D1 (de) | Verbesserung der toxizitätskurven in der chemotherapie. | |
ATE92334T1 (de) | Stabilisierte leukocyten-interferone. | |
IT1178792B (it) | Acilammino mitosani ad attivita'antitumorale e relativo procedimento di preparazione | |
DE69128695T2 (de) | Verbesserung in mikroprozessorbetriebenen Systemen | |
IT1209576B (it) | 4'-alo-antracicline glicosidi. | |
IT8420928A1 (it) | "complesso antibiotico antitumorale bbm-1675" | |
IT8349442A0 (it) | Derivati etendiamminici e guanidinici dotati di attivita' farmacologica | |
BG95488A (bg) | Комплекси съдържащи s+/+/-фенилалканови киселини и алфа-хидроксиалканови киселини | |
FR2539602B3 (fr) | Meuble modulaire convertible | |
ITMI910572A0 (it) | Oligopeptidi eterociclici dotati di attivita' antitumorale | |
DK108885A (da) | Reol | |
IT8449192A1 (it) | Derivati butanolici dotati di attivita' antiaritmica e procedimento di preparazione | |
IT8333804V0 (it) | Mobile componibile per l'arredamento |