IT8348747A0 - Derivati amminometil-benzenici eteroaril-sostituiti ad attivita' regolatrice del ritmo cardiaco e composizioni farmaceutiche che li contengono - Google Patents
Derivati amminometil-benzenici eteroaril-sostituiti ad attivita' regolatrice del ritmo cardiaco e composizioni farmaceutiche che li contengonoInfo
- Publication number
- IT8348747A0 IT8348747A0 IT8348747A IT4874783A IT8348747A0 IT 8348747 A0 IT8348747 A0 IT 8348747A0 IT 8348747 A IT8348747 A IT 8348747A IT 4874783 A IT4874783 A IT 4874783A IT 8348747 A0 IT8348747 A0 IT 8348747A0
- Authority
- IT
- Italy
- Prior art keywords
- aminiomethyl
- heteroaryl
- substituted
- contain
- pharmaceutical compositions
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000001105 regulatory effect Effects 0.000 title 1
- 230000033764 rhythmic process Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/401,752 US4466965A (en) | 1982-07-26 | 1982-07-26 | Phthalazine compounds, compositions and use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8348747A0 true IT8348747A0 (it) | 1983-07-26 |
| IT1205337B IT1205337B (it) | 1989-03-15 |
Family
ID=23589090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT48747/83A IT1205337B (it) | 1982-07-26 | 1983-07-26 | Derivati amminometil-benzenici eteroaril-sostituiti ad attivita' regolatrice del ritmo cardiaco e composizioni farmaceutiche che li contengono |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4466965A (it) |
| EP (2) | EP0114878B1 (it) |
| AU (1) | AU568087B2 (it) |
| CA (1) | CA1240996A (it) |
| DE (1) | DE3381909D1 (it) |
| EG (1) | EG16482A (it) |
| ES (1) | ES524447A0 (it) |
| GR (1) | GR77583B (it) |
| IT (1) | IT1205337B (it) |
| NZ (1) | NZ204885A (it) |
| PH (1) | PH18846A (it) |
| WO (1) | WO1984000489A1 (it) |
| ZA (1) | ZA835224B (it) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4666924A (en) * | 1982-07-26 | 1987-05-19 | E. I. Du Pont De Nemours & Co. | Certain pyridyl substituted aminomethyl benzene derivatives having anti-arrhythmic activity |
| US4923873A (en) * | 1982-07-26 | 1990-05-08 | E. I. Du Pont De Nemours And Company | Quinazoline substituted aminomethyl benzene derivatives |
| FR2567887B1 (fr) * | 1984-07-19 | 1986-12-19 | Rhone Poulenc Sante | Nouveaux amides substitues, leur preparation et les medicaments qui les contiennent |
| EP0222839A4 (en) * | 1985-05-17 | 1988-11-09 | Univ Australian | ANTI-MALARIA COMPOUNDS. |
| US5059620A (en) * | 1985-12-27 | 1991-10-22 | The Du Pont Merck Pharmaceutical Company | Aryl substituted aminomethyl benzene derivatives |
| US4781707A (en) * | 1986-02-18 | 1988-11-01 | Boehringer Laboratories | Process and apparatus for collecting blood from a body cavity for autotransfusion |
| FR2680510B1 (fr) * | 1991-08-20 | 1995-06-23 | Roussel Uclaf | Nouveaux derives bicycliques azotes, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
| FR2672596B1 (fr) * | 1991-02-07 | 1995-07-13 | Roussel Uclaf | Nouveaux derives bicycliques azotes, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
| MX9200299A (es) * | 1991-02-07 | 1992-12-01 | Roussel Uclaf | Nuevos derivados biciclicos nitrogenados, su procedimiento de preparacion los nuevos compuestos intermedios obtenidos su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen. |
| GB9127252D0 (en) * | 1991-12-23 | 1992-02-19 | Boots Co Plc | Therapeutic agents |
| GB9312891D0 (en) * | 1993-06-22 | 1993-08-04 | Boots Co Plc | Therapeutic agents |
| IL112248A0 (en) | 1994-01-25 | 1995-03-30 | Warner Lambert Co | Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them |
| IL112249A (en) | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
| US7067539B2 (en) * | 2001-02-08 | 2006-06-27 | Schering Corporation | Cannabinoid receptor ligands |
| US7507767B2 (en) | 2001-02-08 | 2009-03-24 | Schering Corporation | Cannabinoid receptor ligands |
| TW200302088A (en) | 2001-11-14 | 2003-08-01 | Schering Corp | Cannabinoid receptor ligands |
| CN1662496A (zh) | 2002-06-19 | 2005-08-31 | 先灵公司 | 大麻素受体激动剂 |
| TW200505902A (en) * | 2003-03-20 | 2005-02-16 | Schering Corp | Cannabinoid receptor ligands |
| EP2465502A1 (en) * | 2010-12-15 | 2012-06-20 | Société Splicos | Compounds useful for treating AIDS |
| SG11201510584WA (en) | 2013-06-24 | 2016-01-28 | Merck Patent Gmbh | Phthalazine derivatives |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2474818A (en) * | 1944-09-29 | 1949-07-05 | Parke Davis & Co | Quinoline compounds and process of making same |
| US2474820A (en) * | 1945-02-08 | 1949-07-05 | Parke Davis & Co | Quinoline compounds and process of making same |
| US2419199A (en) * | 1945-02-09 | 1947-04-22 | Parke Davis & Co | Quinoline compounds and process of making same |
| US2474822A (en) * | 1945-11-05 | 1949-07-05 | Parke Davis & Co | Quinoline compounds and process of making same |
| US2474821A (en) * | 1945-11-05 | 1949-07-05 | Parke Davis & Co | Quinoline compounds and process of making same |
| US2474931A (en) * | 1947-01-16 | 1949-07-05 | Parke Davis & Co | Quinoline compounds and process of making same |
| GB750925A (en) * | 1953-10-26 | 1956-06-20 | Wellcome Found | Improvements in and relating to pyridine derivatives and the manufacture thereof |
| US2883382A (en) * | 1957-08-29 | 1959-04-21 | Parke Davis & Co | Benzo-quinolylamino-2-[di(beta-chloroethyl)aminomethyl]-phenols |
| GB974348A (en) * | 1961-01-25 | 1964-11-04 | Parke Davis & Co | Basic 7-chloroquinoline-1-oxide derivatives and methods for their production |
| US3240781A (en) * | 1965-01-06 | 1966-03-15 | Vantorex Ltd | 1-lower alkyl-4-anilinophthalazines |
| NL6707290A (it) * | 1966-05-28 | 1967-11-29 | ||
| US3450707A (en) * | 1966-12-13 | 1969-06-17 | Sterling Drug Inc | Certain 2-anilino-pyridine derivatives |
| CH593266A5 (it) * | 1973-09-20 | 1977-11-30 | Delalande Sa | |
| DE2606592A1 (de) * | 1976-02-19 | 1977-08-25 | Boehringer Sohn Ingelheim | Pyridinderivate |
| FI791727A (fi) * | 1978-06-05 | 1979-12-06 | Ciba Geigy Ag | Foerfarande foer framstaellning av n-alkylerade aminoalkoholer |
| GR71929B (it) * | 1979-11-13 | 1983-08-19 | Ici Ltd | |
| SE1000012A1 (sv) * | 2010-01-08 | 2010-11-09 | Sven A Swallert | Anordning vid en hopfällbar och uppresbar husstomme |
-
1982
- 1982-07-26 US US06/401,752 patent/US4466965A/en not_active Expired - Lifetime
-
1983
- 1983-07-13 NZ NZ204885A patent/NZ204885A/en unknown
- 1983-07-18 AU AU18299/83A patent/AU568087B2/en not_active Ceased
- 1983-07-18 EP EP83902608A patent/EP0114878B1/en not_active Expired - Lifetime
- 1983-07-18 ZA ZA835224A patent/ZA835224B/xx unknown
- 1983-07-18 WO PCT/US1983/001103 patent/WO1984000489A1/en active IP Right Grant
- 1983-07-18 DE DE8383902608T patent/DE3381909D1/de not_active Expired - Lifetime
- 1983-07-18 EP EP88201796A patent/EP0310155A1/en not_active Withdrawn
- 1983-07-22 PH PH29273A patent/PH18846A/en unknown
- 1983-07-25 GR GR72021A patent/GR77583B/el unknown
- 1983-07-26 ES ES524447A patent/ES524447A0/es active Granted
- 1983-07-26 EG EG452/83A patent/EG16482A/xx active
- 1983-07-26 CA CA000433226A patent/CA1240996A/en not_active Expired
- 1983-07-26 IT IT48747/83A patent/IT1205337B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| US4466965A (en) | 1984-08-21 |
| CA1240996A (en) | 1988-08-23 |
| EP0114878A1 (en) | 1984-08-08 |
| ES8501362A1 (es) | 1984-12-01 |
| AU1829983A (en) | 1984-02-23 |
| WO1984000489A1 (en) | 1984-02-16 |
| EP0114878A4 (en) | 1986-03-18 |
| AU568087B2 (en) | 1987-12-17 |
| DE3381909D1 (de) | 1990-10-31 |
| PH18846A (en) | 1985-10-14 |
| GR77583B (it) | 1984-09-24 |
| EG16482A (en) | 1991-12-30 |
| NZ204885A (en) | 1986-01-24 |
| ES524447A0 (es) | 1984-12-01 |
| EP0114878B1 (en) | 1990-09-26 |
| EP0310155A1 (en) | 1989-04-05 |
| ZA835224B (en) | 1984-03-28 |
| IT1205337B (it) | 1989-03-15 |
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