GR77583B - - Google Patents

Info

Publication number
GR77583B
GR77583B GR72021A GR830172021A GR77583B GR 77583 B GR77583 B GR 77583B GR 72021 A GR72021 A GR 72021A GR 830172021 A GR830172021 A GR 830172021A GR 77583 B GR77583 B GR 77583B
Authority
GR
Greece
Application number
GR72021A
Inventor
David M Stout
William L Matier
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of GR77583B publication Critical patent/GR77583B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • C07D215/44Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • C07D237/34Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GR72021A 1982-07-26 1983-07-25 GR77583B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/401,752 US4466965A (en) 1982-07-26 1982-07-26 Phthalazine compounds, compositions and use

Publications (1)

Publication Number Publication Date
GR77583B true GR77583B (el) 1984-09-24

Family

ID=23589090

Family Applications (1)

Application Number Title Priority Date Filing Date
GR72021A GR77583B (el) 1982-07-26 1983-07-25

Country Status (13)

Country Link
US (1) US4466965A (el)
EP (2) EP0310155A1 (el)
AU (1) AU568087B2 (el)
CA (1) CA1240996A (el)
DE (1) DE3381909D1 (el)
EG (1) EG16482A (el)
ES (1) ES524447A0 (el)
GR (1) GR77583B (el)
IT (1) IT1205337B (el)
NZ (1) NZ204885A (el)
PH (1) PH18846A (el)
WO (1) WO1984000489A1 (el)
ZA (1) ZA835224B (el)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666924A (en) * 1982-07-26 1987-05-19 E. I. Du Pont De Nemours & Co. Certain pyridyl substituted aminomethyl benzene derivatives having anti-arrhythmic activity
US4923873A (en) * 1982-07-26 1990-05-08 E. I. Du Pont De Nemours And Company Quinazoline substituted aminomethyl benzene derivatives
FR2567887B1 (fr) * 1984-07-19 1986-12-19 Rhone Poulenc Sante Nouveaux amides substitues, leur preparation et les medicaments qui les contiennent
EP0222839A4 (en) * 1985-05-17 1988-11-09 Univ Australian ANTI-MALARIA COMPOUNDS.
US5059620A (en) * 1985-12-27 1991-10-22 The Du Pont Merck Pharmaceutical Company Aryl substituted aminomethyl benzene derivatives
US4781707A (en) * 1986-02-18 1988-11-01 Boehringer Laboratories Process and apparatus for collecting blood from a body cavity for autotransfusion
FR2672596B1 (fr) * 1991-02-07 1995-07-13 Roussel Uclaf Nouveaux derives bicycliques azotes, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
FR2680510B1 (fr) * 1991-08-20 1995-06-23 Roussel Uclaf Nouveaux derives bicycliques azotes, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
MX9200299A (es) * 1991-02-07 1992-12-01 Roussel Uclaf Nuevos derivados biciclicos nitrogenados, su procedimiento de preparacion los nuevos compuestos intermedios obtenidos su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen.
GB9127252D0 (en) * 1991-12-23 1992-02-19 Boots Co Plc Therapeutic agents
GB9312891D0 (en) * 1993-06-22 1993-08-04 Boots Co Plc Therapeutic agents
IL112248A0 (en) 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
IL112249A (en) 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
US7067539B2 (en) * 2001-02-08 2006-06-27 Schering Corporation Cannabinoid receptor ligands
US7507767B2 (en) * 2001-02-08 2009-03-24 Schering Corporation Cannabinoid receptor ligands
EP1444203A1 (en) * 2001-11-14 2004-08-11 Schering Corporation Cannabinoid receptor ligands
MXPA04012704A (es) 2002-06-19 2005-03-23 Schering Corp Agonistas de los receptores canabinoides.
TW200505902A (en) * 2003-03-20 2005-02-16 Schering Corp Cannabinoid receptor ligands
EP2465502A1 (en) * 2010-12-15 2012-06-20 Société Splicos Compounds useful for treating AIDS
DK3013804T3 (en) * 2013-06-24 2017-04-10 Merck Patent Gmbh phthalazine

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2474818A (en) * 1944-09-29 1949-07-05 Parke Davis & Co Quinoline compounds and process of making same
US2474820A (en) * 1945-02-08 1949-07-05 Parke Davis & Co Quinoline compounds and process of making same
US2419199A (en) * 1945-02-09 1947-04-22 Parke Davis & Co Quinoline compounds and process of making same
US2474821A (en) * 1945-11-05 1949-07-05 Parke Davis & Co Quinoline compounds and process of making same
US2474822A (en) * 1945-11-05 1949-07-05 Parke Davis & Co Quinoline compounds and process of making same
US2474931A (en) * 1947-01-16 1949-07-05 Parke Davis & Co Quinoline compounds and process of making same
GB750925A (en) * 1953-10-26 1956-06-20 Wellcome Found Improvements in and relating to pyridine derivatives and the manufacture thereof
US2883382A (en) * 1957-08-29 1959-04-21 Parke Davis & Co Benzo-quinolylamino-2-[di(beta-chloroethyl)aminomethyl]-phenols
GB974348A (en) * 1961-01-25 1964-11-04 Parke Davis & Co Basic 7-chloroquinoline-1-oxide derivatives and methods for their production
US3240781A (en) * 1965-01-06 1966-03-15 Vantorex Ltd 1-lower alkyl-4-anilinophthalazines
NL6707290A (el) * 1966-05-28 1967-11-29
US3450707A (en) * 1966-12-13 1969-06-17 Sterling Drug Inc Certain 2-anilino-pyridine derivatives
CH593266A5 (el) * 1973-09-20 1977-11-30 Delalande Sa
DE2606592A1 (de) * 1976-02-19 1977-08-25 Boehringer Sohn Ingelheim Pyridinderivate
FI791727A (fi) * 1978-06-05 1979-12-06 Ciba Geigy Ag Foerfarande foer framstaellning av n-alkylerade aminoalkoholer
GR71929B (el) * 1979-11-13 1983-08-19 Ici Ltd
SE1000012A1 (sv) * 2010-01-08 2010-11-09 Sven A Swallert Anordning vid en hopfällbar och uppresbar husstomme

Also Published As

Publication number Publication date
EP0114878A1 (en) 1984-08-08
AU1829983A (en) 1984-02-23
US4466965A (en) 1984-08-21
EP0310155A1 (en) 1989-04-05
WO1984000489A1 (en) 1984-02-16
CA1240996A (en) 1988-08-23
EP0114878B1 (en) 1990-09-26
IT8348747A0 (it) 1983-07-26
PH18846A (en) 1985-10-14
IT1205337B (it) 1989-03-15
EP0114878A4 (en) 1986-03-18
DE3381909D1 (de) 1990-10-31
ES8501362A1 (es) 1984-12-01
ES524447A0 (es) 1984-12-01
AU568087B2 (en) 1987-12-17
NZ204885A (en) 1986-01-24
ZA835224B (en) 1984-03-28
EG16482A (en) 1991-12-30

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