IT8249476A0 - Esteri di derivati della arilossipropanolammina aventi attivita'beta-bloccante - Google Patents

Esteri di derivati della arilossipropanolammina aventi attivita'beta-bloccante

Info

Publication number
IT8249476A0
IT8249476A0 IT8249476A IT4947682A IT8249476A0 IT 8249476 A0 IT8249476 A0 IT 8249476A0 IT 8249476 A IT8249476 A IT 8249476A IT 4947682 A IT4947682 A IT 4947682A IT 8249476 A0 IT8249476 A0 IT 8249476A0
Authority
IT
Italy
Prior art keywords
beta
esters
blocking activity
aryloxypropanolamine derivatives
aryloxypropanolamine
Prior art date
Application number
IT8249476A
Other languages
English (en)
Other versions
IT1149117B (it
Inventor
Paul W Erhardt
William L Matier
Original Assignee
American Hospital Supply Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Hospital Supply Corp filed Critical American Hospital Supply Corp
Publication of IT8249476A0 publication Critical patent/IT8249476A0/it
Application granted granted Critical
Publication of IT1149117B publication Critical patent/IT1149117B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/101,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/14Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/34Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT49476/82A 1981-11-12 1982-11-12 Esteri di derivati della arilossi-propanolammina aventi attivita' beta-bloccante IT1149117B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32077281A 1981-01-12 1981-01-12

Publications (2)

Publication Number Publication Date
IT8249476A0 true IT8249476A0 (it) 1982-11-12
IT1149117B IT1149117B (it) 1986-12-03

Family

ID=23247810

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49476/82A IT1149117B (it) 1981-11-12 1982-11-12 Esteri di derivati della arilossi-propanolammina aventi attivita' beta-bloccante

Country Status (13)

Country Link
EP (1) EP0093155B1 (it)
JP (1) JPS58501725A (it)
AU (1) AU555517B2 (it)
CA (1) CA1201437A (it)
DE (1) DE3272925D1 (it)
EG (1) EG17255A (it)
ES (2) ES517295A0 (it)
GR (1) GR78295B (it)
IL (1) IL67242A0 (it)
IT (1) IT1149117B (it)
NZ (1) NZ202229A (it)
WO (1) WO1983001772A1 (it)
ZA (1) ZA827646B (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56108B1 (en) * 1982-07-16 1991-04-24 Carpibem 1-(2-carbalkoxy-4-(thienylcarboxamido)phenoxy)-3-amino 2-propanols,their preparation and applications thereof in therapeutics
US4508725A (en) * 1982-12-22 1985-04-02 American Hospital Supply Corporation Esters of 3-(3-substituted-amino-2-hydroxypropoxy)-4-substituted-1,2,5-thiadiazole derivatives
US5202347A (en) * 1984-03-14 1993-04-13 Bodor Nicholas S Soft β-adrenergic blocking agents
US4829086A (en) * 1984-03-14 1989-05-09 Bodor Nicholas S Soft β-adrenergic blocking agents
US5334601A (en) * 1984-03-14 1994-08-02 Bodor Nicholas S Soft β-adrenergic blocking agents
US5135926A (en) * 1984-03-14 1992-08-04 Bodor Nicholas S Soft β-adrenergic blocking agents
US4593039A (en) * 1984-04-02 1986-06-03 Merck & Co., Inc. 1-aryloxy-3-(substituted aminoalkylamino)-2-propanols
US4605513A (en) * 1984-08-08 1986-08-12 Eli Lilly And Company Process for inhibiting peptide carbamylation
AU2061588A (en) * 1987-09-07 1989-03-09 Imperial Chemical Industries Plc Phenol ester of xamoterol
US5229412A (en) * 1988-03-25 1993-07-20 The Board Of Trustees Of The Leland Stanford Junior University Method for relieving anxiety using 5-hydroxytryptamine-1a-receptor-binding compounds
US4935422A (en) * 1988-12-15 1990-06-19 E. I. Du Pont De Nemours And Company Acyloxypropanolamines
CA2015730C (en) * 1989-05-12 1997-10-07 Sadahiko Iguchi Esters of phenylalkanoic acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2132570B1 (it) * 1971-04-09 1974-08-02 Lipha
US3729477A (en) * 1971-09-09 1973-04-24 Frosst & Co Charles E Certain 4-(3-amino-2-hydroxypropoxy)-1,2,5-thiadiazole-3-carboxamides
US4083992A (en) * 1972-12-15 1978-04-11 Imperial Chemical Industries Limited Alkanolamine derivatives

Also Published As

Publication number Publication date
ZA827646B (en) 1983-08-31
CA1201437A (en) 1986-03-04
ES8401012A1 (es) 1983-12-01
ES523878A0 (es) 1984-11-01
EP0093155B1 (en) 1986-08-27
EP0093155A1 (en) 1983-11-09
IL67242A0 (en) 1983-03-31
ES517295A0 (es) 1983-12-01
WO1983001772A1 (en) 1983-05-26
ES8500884A1 (es) 1984-11-01
DE3272925D1 (en) 1986-10-02
JPS58501725A (ja) 1983-10-13
GR78295B (it) 1984-09-26
AU555517B2 (en) 1986-09-25
IT1149117B (it) 1986-12-03
EP0093155A4 (en) 1984-04-24
EG17255A (en) 1990-08-30
NZ202229A (en) 1985-11-08

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Effective date: 19941027