IT8121137A0 - Processo per la preparazione di acido ursodeossicolico ad alta purezza. - Google Patents
Processo per la preparazione di acido ursodeossicolico ad alta purezza.Info
- Publication number
- IT8121137A0 IT8121137A0 IT8121137A IT2113781A IT8121137A0 IT 8121137 A0 IT8121137 A0 IT 8121137A0 IT 8121137 A IT8121137 A IT 8121137A IT 2113781 A IT2113781 A IT 2113781A IT 8121137 A0 IT8121137 A0 IT 8121137A0
- Authority
- IT
- Italy
- Prior art keywords
- preparation
- high purity
- ursodeoxycholic acid
- purity ursodeoxycholic
- acid
- Prior art date
Links
- RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 title 1
- RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 title 1
- 229960001661 ursodiol Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21137/81A IT1137459B (it) | 1981-04-14 | 1981-04-14 | Prodesso per la preparazione di acido ursodeossicolico ad alta purezza |
US06/277,005 US4379093A (en) | 1981-04-14 | 1981-06-24 | Process for preparing high purity ursodeoxycholic acid |
AT82830083T ATE15207T1 (de) | 1981-04-14 | 1982-04-05 | Verfahren zur herstellung von ursodeoxycholsaeure hoher reinheit. |
DE8282830083T DE3265743D1 (en) | 1981-04-14 | 1982-04-05 | Process for preparing high purity ursodeoxycholic acid |
IE803/82A IE53198B1 (en) | 1981-04-14 | 1982-04-05 | Process for preparing highly pure ursodeoxycholic acid |
EP82830083A EP0063106B1 (en) | 1981-04-14 | 1982-04-05 | Process for preparing high purity ursodeoxycholic acid |
YU802/82A YU43074B (en) | 1981-04-14 | 1982-04-13 | Process for obtaining ursodeoxy cholic acid of high purity |
CA000400880A CA1185233A (en) | 1981-04-14 | 1982-04-13 | Process for preparing high purity ursodeoxycholic acid |
NO821194A NO162665C (no) | 1981-04-14 | 1982-04-13 | Fremgangsmaate ved fremstilling av ursodeoxycholsyre av hoey renhet. |
DK164882A DK164882A (da) | 1981-04-14 | 1982-04-13 | Fremgangsmaade til fremstilling af 3-alfa-7-beta-dihydrocholansyre |
ES511382A ES8307835A1 (es) | 1981-04-14 | 1982-04-13 | "un procedimiento para la preparacion de acido ursodeoxicolico de alta pureza". |
JP57061161A JPS57203097A (en) | 1981-04-14 | 1982-04-14 | Manufacture of high purity ulsodeoxycholic acid |
PT74749A PT74749B (en) | 1981-04-14 | 1982-04-14 | Process for preparing high purity ursodeoxycholic acid |
NO853328A NO162562C (no) | 1981-04-14 | 1985-08-23 | 3-alfa,-7beta-dihydroxy-12-keto-5beta-cholansyre og dennes tris-trimethylsilynderivat. |
JP61308927A JPS62161798A (ja) | 1981-04-14 | 1986-12-26 | 3α,7β−ジヒドロキシ−12−ケトコラン酸系化合物及びその製造方法 |
JP2234631A JPH03128392A (ja) | 1981-04-14 | 1990-09-06 | 3α,7β―ジヒドロキシ―12―ケト―5β―コラン酸の精製方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21137/81A IT1137459B (it) | 1981-04-14 | 1981-04-14 | Prodesso per la preparazione di acido ursodeossicolico ad alta purezza |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8121137A0 true IT8121137A0 (it) | 1981-04-14 |
IT1137459B IT1137459B (it) | 1986-09-10 |
Family
ID=11177288
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT21137/81A IT1137459B (it) | 1981-04-14 | 1981-04-14 | Prodesso per la preparazione di acido ursodeossicolico ad alta purezza |
Country Status (13)
Country | Link |
---|---|
US (1) | US4379093A (it) |
EP (1) | EP0063106B1 (it) |
JP (3) | JPS57203097A (it) |
AT (1) | ATE15207T1 (it) |
CA (1) | CA1185233A (it) |
DE (1) | DE3265743D1 (it) |
DK (1) | DK164882A (it) |
ES (1) | ES8307835A1 (it) |
IE (1) | IE53198B1 (it) |
IT (1) | IT1137459B (it) |
NO (1) | NO162665C (it) |
PT (1) | PT74749B (it) |
YU (1) | YU43074B (it) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2511007A1 (fr) * | 1981-08-07 | 1983-02-11 | Roussel Uclaf | Procede de preparation de l'acide ursodesoxycholique a partir de l'acide 3a, 7b, 12a-trihydroxycholanique et produit intermediaire utilises |
IT1150756B (it) * | 1982-04-02 | 1986-12-17 | Zambon Spa | Procedimento per preparare l'acido 3alfa, 7beta-diidrossi-5beta-colanico |
FR2653128B1 (fr) * | 1989-10-17 | 1995-03-17 | Sanofi Sa | Procede pour la preparation de l'acide chenodesoxycholique. |
FR2653129B1 (fr) * | 1989-10-17 | 1995-03-17 | Sanofi Sa | Procede pour la preparation de 7-oxocholanates. |
EP0424232B1 (fr) * | 1989-10-17 | 1996-02-21 | Sanofi | Procédé de préparation de l'acide |
FR2653127B1 (fr) * | 1989-10-17 | 1994-12-09 | Sanofi Sa | Procede pour la preparation de 12-oxocholanates. |
JPH04152543A (ja) * | 1990-10-16 | 1992-05-26 | Agency Of Ind Science & Technol | 自己検査機能を有する集積回路構造体、及びこれを用いた集積回路良品チップの選別方法 |
NZ245504A (en) * | 1991-12-20 | 1995-08-28 | Hoechst Ag | Bile acid derivatives containing an ethylenically unsaturated grouping |
DE4432708A1 (de) * | 1994-09-14 | 1996-03-21 | Hoechst Ag | Modifizierte Gallensäuren, Verfahren zu ihrer Herstellung und ihre Verwendung |
KR20010043558A (ko) * | 1998-05-13 | 2001-05-25 | 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 | 감수분열 조절 화합물 |
CA2440680C (en) | 2001-03-12 | 2010-06-01 | Roberto Pellicciari | Steroids as agonists for fxr |
BRPI0418963A (pt) * | 2004-07-20 | 2007-12-04 | Libbs Farmaceutica Ltda | composição para redução de gordura localizada, uso de compostos tensoativos farmceuticamente aceitáveis e métodos para redução de gordura localizada |
AU2013277429B2 (en) * | 2012-06-19 | 2016-01-14 | Intercept Pharmaceuticals, Inc. | Preparation, uses and solid forms of obeticholic acid |
CN114195852A (zh) * | 2021-12-28 | 2022-03-18 | 中山百灵生物技术股份有限公司 | 一种3β,7β-二羟基-5β-胆烷酸的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5012434A (it) * | 1973-06-04 | 1975-02-08 | ||
JPS5233638A (en) * | 1975-09-08 | 1977-03-14 | Mitsui Petrochem Ind Ltd | Process for preparation of aromatic alcohols |
JPS5323302A (en) * | 1976-08-18 | 1978-03-03 | Mitsui Petrochem Ind Ltd | Thermal cracking of hydrocarbons |
JPS5536680A (en) * | 1978-09-08 | 1980-03-14 | Jidosha Kiki Co Ltd | Flow control valve |
FR2446293A1 (fr) * | 1978-12-11 | 1980-08-08 | Roussel Uclaf | Procede de purification de l'acide chenodesoxycholique |
FR2444048B1 (it) * | 1978-12-15 | 1981-08-14 | Roussel Uclaf | |
IT1165252B (it) * | 1979-07-12 | 1987-04-22 | Blasinachim Spa | Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati |
-
1981
- 1981-04-14 IT IT21137/81A patent/IT1137459B/it active
- 1981-06-24 US US06/277,005 patent/US4379093A/en not_active Expired - Fee Related
-
1982
- 1982-04-05 IE IE803/82A patent/IE53198B1/en not_active IP Right Cessation
- 1982-04-05 EP EP82830083A patent/EP0063106B1/en not_active Expired
- 1982-04-05 AT AT82830083T patent/ATE15207T1/de not_active IP Right Cessation
- 1982-04-05 DE DE8282830083T patent/DE3265743D1/de not_active Expired
- 1982-04-13 CA CA000400880A patent/CA1185233A/en not_active Expired
- 1982-04-13 DK DK164882A patent/DK164882A/da not_active Application Discontinuation
- 1982-04-13 YU YU802/82A patent/YU43074B/xx unknown
- 1982-04-13 ES ES511382A patent/ES8307835A1/es not_active Expired
- 1982-04-13 NO NO821194A patent/NO162665C/no unknown
- 1982-04-14 PT PT74749A patent/PT74749B/pt not_active IP Right Cessation
- 1982-04-14 JP JP57061161A patent/JPS57203097A/ja active Granted
-
1986
- 1986-12-26 JP JP61308927A patent/JPS62161798A/ja active Granted
-
1990
- 1990-09-06 JP JP2234631A patent/JPH03128392A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS62161798A (ja) | 1987-07-17 |
CA1185233A (en) | 1985-04-09 |
DK164882A (da) | 1982-10-15 |
JPS57203097A (en) | 1982-12-13 |
DE3265743D1 (en) | 1985-10-03 |
NO821194L (no) | 1982-10-15 |
NO162665C (no) | 1990-01-31 |
ES511382A0 (es) | 1983-09-01 |
JPH0132238B2 (it) | 1989-06-29 |
ATE15207T1 (de) | 1985-09-15 |
US4379093A (en) | 1983-04-05 |
IT1137459B (it) | 1986-09-10 |
YU80282A (en) | 1985-04-30 |
JPS6320439B2 (it) | 1988-04-27 |
IE820803L (en) | 1982-10-14 |
IE53198B1 (en) | 1988-08-31 |
NO162665B (no) | 1989-10-23 |
YU43074B (en) | 1989-02-28 |
EP0063106A1 (en) | 1982-10-20 |
JPH045680B2 (it) | 1992-02-03 |
ES8307835A1 (es) | 1983-09-01 |
PT74749A (en) | 1982-05-01 |
PT74749B (en) | 1983-11-08 |
EP0063106B1 (en) | 1985-08-28 |
JPH03128392A (ja) | 1991-05-31 |
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Legal Events
Date | Code | Title | Description |
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TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19940428 |